Junping Wen
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View article: Clinical Features of Chinese Patients with Thyroid Eye Disease: A Multicenter Retrospective Study
Clinical Features of Chinese Patients with Thyroid Eye Disease: A Multicenter Retrospective Study Open
Background: Thyroid eye disease (TED) is a debilitating autoimmune disorder linked to thyroid dysfunction. There is limited knowledge of TED in Asian populations. This multicenter study characterizes the clinical features and treatment res…
View article: Identification of crosstalk genes and diagnostic biomarkers in systemic sclerosis associated sarcopenia through integrative analysis and machine learning
Identification of crosstalk genes and diagnostic biomarkers in systemic sclerosis associated sarcopenia through integrative analysis and machine learning Open
Background Sarcopenia associated with systemic sclerosis (SSc) significantly compromises patient prognosis and quality of life. However, reliable diagnostic biomarkers remain lacking. This study aimed to identify molecular markers for earl…
View article: Metabolic complications and clinical outcomes of non-functioning adrenal incidentalomas: a systematic review and meta-analysis
Metabolic complications and clinical outcomes of non-functioning adrenal incidentalomas: a systematic review and meta-analysis Open
In patients with NFAI, subtle hormone secretion may exist despite current diagnostic criteria suggesting non-functionality. Such tumors show significant associations with metabolic disorders, particularly diabetes mellitus and dyslipidemia…
View article: Weight-adjusted-waist index is associated with increased risk of sleep disturbances in the U.S. adult population: an analysis of NHANES 2007–2012
Weight-adjusted-waist index is associated with increased risk of sleep disturbances in the U.S. adult population: an analysis of NHANES 2007–2012 Open
Level III: Evidence obtained from well-designed cohort or case-control analytic studies.
View article: Metaverse Clinic for Pregnant Women With Subclinical Hypothyroidism: Prospective Randomized Study
Metaverse Clinic for Pregnant Women With Subclinical Hypothyroidism: Prospective Randomized Study Open
Background Health care is experiencing new opportunities in the emerging digital landscape. The metaverse, a shared virtual space, integrates technologies such as augmented reality, virtual reality, blockchain, and artificial intelligence.…
View article: Causal association between thyroid function and the risk of infertility: a Mendelian randomization study
Causal association between thyroid function and the risk of infertility: a Mendelian randomization study Open
Objectives Thyroid dysfunction is commonly associated with the risk of infertility in both females and males. However, recent randomized controlled trials have demonstrated that thyroid function levels in females are not significantly rela…
View article: 5045 The Effects Of Non-functioning Adrenal Incidentalomas On Metabolic Comorbidities And Clinical Characteristics Changes: A Systematic Review And Meta-Analysis
5045 The Effects Of Non-functioning Adrenal Incidentalomas On Metabolic Comorbidities And Clinical Characteristics Changes: A Systematic Review And Meta-Analysis Open
Disclosure: X. Li: None. H. Lan: None. J. Wen: None. G. Chen: None. W. Lin: None. The Effects of Non-functioning Adrenal Incidentalomas on Metabolic Comorbidities and Clinical Characteristics Changes: A Systematic Review and Meta-analysis.…
View article: Survival benefit of postoperative radioiodine therapy among patients with intermediate-risk differentiated thyroid carcinoma
Survival benefit of postoperative radioiodine therapy among patients with intermediate-risk differentiated thyroid carcinoma Open
Background The 2015 American Thyroid Association (ATA) guidelines proposed the ATA Risk Stratification System and American Joint Committee on Cancer Tumor-Node-Metastasis (AJCC/TNM) Staging System for postoperative radioiodine decision-mak…
View article: Socioeconomic disparities and regional environment are associated with cervical lymph node metastases in children and adolescents with differentiated thyroid cancer: developing a web-based predictive model
Socioeconomic disparities and regional environment are associated with cervical lymph node metastases in children and adolescents with differentiated thyroid cancer: developing a web-based predictive model Open
Purpose To establish an online predictive model for the prediction of cervical lymph node metastasis (CLNM) in children and adolescents with differentiated thyroid cancer (caDTC). And analyze the impact between socioeconomic disparities, r…
View article: Effect of hemoglobin A1c management levels on coronary physiology evaluated by quantitative flow ratio in patients who underwent percutaneous coronary intervention
Effect of hemoglobin A1c management levels on coronary physiology evaluated by quantitative flow ratio in patients who underwent percutaneous coronary intervention Open
Aims/Introduction The coronary physiology and prognosis of patients with different hemoglobin A1c (HbA1c) levels after percutaneous coronary intervention (PCI) are currently unknown. The aim of this study was to assess the effect of differ…
View article: Klotho Reduces the Risk of Osteoporosis in Postmenopausal Women: A cross-sectional Study of the National Health and Nutrition Examination Survey (NHANES)
Klotho Reduces the Risk of Osteoporosis in Postmenopausal Women: A cross-sectional Study of the National Health and Nutrition Examination Survey (NHANES) Open
Background: We explored a convenient and accurate factor to predict the risk factors of osteoporosis (OP) in postmenopausal women based on the study of the database. Methods: This is a retrospective study. We searched and collected the dat…
View article: Supplementary Material for: Eyelid metastasis cervical cancer: a case report
Supplementary Material for: Eyelid metastasis cervical cancer: a case report Open
Metastatic malignant lesions of the eyelids are less than 1% of all eyelid tumors. Eyelid metastasis from the cervix, particularly the first sign of metastasis, has not been reported. A female presented to an ophthalmologist with a gradual…
View article: Supplementary Material for: The Effect of Preoperative Tamsulosin on Ureteral Navigation, Operation, and Safety: A Systematic Review and Meta-Analysis
Supplementary Material for: The Effect of Preoperative Tamsulosin on Ureteral Navigation, Operation, and Safety: A Systematic Review and Meta-Analysis Open
Introduction: Urolithiasis is one of the most common diseases in the world, and at present, ureteroscopy (URS) is the first choice for its treatment. Although the effect is good, there is a risk of insertion failure of ureteroscope. Tamsul…
View article: Antibody responses to COVID‐19 vaccination in people with obesity: A systematic review and meta‐analysis
Antibody responses to COVID‐19 vaccination in people with obesity: A systematic review and meta‐analysis Open
COVID‐19 vaccine is critical in preventing SARS‐CoV‐2 infection and transmission. However, obesity's effect on immune responses to COVID‐19 vaccines is still unknown. We performed a meta‐analysis of the literature and compared antibody res…
View article: Value of machine learning algorithms for predicting diabetes risk: A subset analysis from a real‐world retrospective cohort study
Value of machine learning algorithms for predicting diabetes risk: A subset analysis from a real‐world retrospective cohort study Open
Aims/Introduction To compare the application value of different machine learning (ML) algorithms for diabetes risk prediction. Materials and Methods This is a 3‐year retrospective cohort study with a total of 3,687 participants being inclu…
View article: Exploring risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: construction of a novel population-based predictive model
Exploring risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: construction of a novel population-based predictive model Open
Background Machine learning was a highly effective tool in model construction. We aim to establish a machine learning-based predictive model for predicting the cervical lymph node metastasis (LNM) in papillary thyroid microcarcinoma (PTMC)…
View article: Changes in bone mineral density after bariatric surgery in patients of different ages or patients with different postoperative periods: a systematic review and meta-analysis
Changes in bone mineral density after bariatric surgery in patients of different ages or patients with different postoperative periods: a systematic review and meta-analysis Open
To assess changes in bone mineral density (BMD) following bariatric surgery (BS) in patients with different bone sites, postoperative periods and ages. Twenty-two studies were included. Femoral neck (FN) BMD decreased after surgery (MD, − …
View article: Surgical Methods and Social Factors Are Associated With Long-Term Survival in Follicular Thyroid Carcinoma: Construction and Validation of a Prognostic Model Based on Machine Learning Algorithms
Surgical Methods and Social Factors Are Associated With Long-Term Survival in Follicular Thyroid Carcinoma: Construction and Validation of a Prognostic Model Based on Machine Learning Algorithms Open
Background This study aimed to establish and verify an effective machine learning (ML) model to predict the prognosis of follicular thyroid cancer (FTC), and compare it with the eighth edition of the American Joint Committee on Cancer (AJC…
View article: Hypothalamic Kisspeptin Neurons Regulates Energy Metabolism and Reproduction Under Chronic Stress
Hypothalamic Kisspeptin Neurons Regulates Energy Metabolism and Reproduction Under Chronic Stress Open
Background Stress activates the hypothalamic-pituitary-adrenal (HPA) axis, affecting energy homeostasis and reproduction. The aim of this study was to investigate whether stress affected energy metabolism and reproduction through the gluco…
View article: Association between sleep duration and incidence of type 2 diabetes in China: the REACTION study
Association between sleep duration and incidence of type 2 diabetes in China: the REACTION study Open
Backgrounds: Inadequate sleep duration is associated with a higher risk of type 2 diabetes and the relationship is nonlinear. We aim to assess the curve relationship between night sleep duration and the incidence of type 2 diabetes in Chin…
View article: Combined T4 + T3 therapy versus T4 monotherapy effect on psychological health in hypothyroidism: A systematic review and meta‐analysis
Combined T4 + T3 therapy versus T4 monotherapy effect on psychological health in hypothyroidism: A systematic review and meta‐analysis Open
Purpose To evaluate whether T4 + T3 combination therapy had advantages in improving psychological health compared with T4 monotherapy. Methods We searched PubMed, Embase, Cochrane Library, and Web of Science from January 2000 to March 2021…
View article: Development of a Risk Model for Predicting Microalbuminuria in the Chinese Population Using Machine Learning Algorithms
Development of a Risk Model for Predicting Microalbuminuria in the Chinese Population Using Machine Learning Algorithms Open
Objective Microalbuminuria (MAU) occurs due to universal endothelial damage, which is strongly associated with kidney disease, stroke, myocardial infarction, and coronary artery disease. Screening patients at high risk for MAU may aid in t…
View article: Association of soy food with cardiovascular outcomes and all-cause mortality in a Chinese population: a nationwide prospective cohort study
Association of soy food with cardiovascular outcomes and all-cause mortality in a Chinese population: a nationwide prospective cohort study Open
High soy intake was associated with a reduced risk of total CVD events and all-cause mortality among a Chinese population.