Jialin Ye
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View article: A neural circuit for female-specific defensive homeostasis in risk assessment
A neural circuit for female-specific defensive homeostasis in risk assessment Open
SUMMARY Risk assessment in defensive behavior is an adaptive mechanism shaped by natural selection, enabling individuals to evaluate potential threats and thereby maintain defensive homeostasis. Although risk assessment is essential for su…
View article: Hierarchical behavioral analysis framework as a platform for standardized quantitative identification of behaviors
Hierarchical behavioral analysis framework as a platform for standardized quantitative identification of behaviors Open
View article: Hierarchical behavioral analysis framework as a platform for standardized quantitative identification of behaviors
Hierarchical behavioral analysis framework as a platform for standardized quantitative identification of behaviors Open
Behavior is composed of modules that operate based on inherent logic. Understanding behavior and its neural mechanisms is facilitated by clear structural behavioral analysis. Here, we developed a hierarchical behavioral analysis framework …
View article: Ginkgetin Alleviates Inflammation and Senescence by Targeting STING
Ginkgetin Alleviates Inflammation and Senescence by Targeting STING Open
Ginkgo biloba extract is reported to have therapeutic effects on aging‐related disorders. However, the specific component responsible for this biological function and its mechanism of action remain largely unknown. This study finds that Gi…
View article: Chemoradiotherapy-induced ACKR2+ tumor cells drive CD8+ T cell senescence and cervical cancer recurrence
Chemoradiotherapy-induced ACKR2+ tumor cells drive CD8+ T cell senescence and cervical cancer recurrence Open
Tumor recurrence after chemoradiotherapy is challenging to overcome, and approaches to predict the recurrence remain elusive. Here, human cervical cancer tissues before and after concurrent chemoradiotherapy (CCRT) analyzed by single-cell …
View article: Research Progress of Triage Standard for Pediatric
Research Progress of Triage Standard for Pediatric Open
Pediatric emergency pre-examination triage plays a vital role in pediatric emergency treatment. At present, many international emergency triage systems have been standardized, but there is still a lack of unified standard emergency pediatr…
View article: Hierarchical Behavioral Analysis Framework (HBAF) as a Platform for Standardized Quantitative Identification of Behaviors
Hierarchical Behavioral Analysis Framework (HBAF) as a Platform for Standardized Quantitative Identification of Behaviors Open
View article: Cytoplasmic DNA sensing boosts CD4+ T cell metabolism for inflammatory induction
Cytoplasmic DNA sensing boosts CD4+ T cell metabolism for inflammatory induction Open
DNA accumulation is associated with the development of autoimmune inflammatory diseases. However, the pathological role and underlying mechanism of cytoplasmic DNA accumulation in CD4+ T cells have not been well established. Here, we show …
View article: Goliath induces inflammation in obese mice by linking fatty acid β‐oxidation to glycolysis
Goliath induces inflammation in obese mice by linking fatty acid β‐oxidation to glycolysis Open
Obesity is associated with metabolic disorders and chronic inflammation. However, the obesity‐associated metabolic contribution to inflammatory induction remains elusive. Here, we show that, compared with lean mice, CD4 + T cells from obes…
View article: Connectivity Map of Subthalamic Corticotropin-releasing Hormone Neurons in the Mouse Brain
Connectivity Map of Subthalamic Corticotropin-releasing Hormone Neurons in the Mouse Brain Open
View article: Cytoplasmic DNA sensing by KU complex in aged CD4+ T cell potentiates T cell activation and aging-related autoimmune inflammation
Cytoplasmic DNA sensing by KU complex in aged CD4+ T cell potentiates T cell activation and aging-related autoimmune inflammation Open
View article: Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation
Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation Open
Amyloid-β (Aβ) accumulation in the brain is a hallmark of Alzheimer's disease (AD) pathology. However, the molecular mechanism controlling microglial Aβ phagocytosis is poorly understood. Here we found that the E3 ubiquitin ligase Pellino …
View article: 3D-Finite Element Analysis for Influences of PCM Inserted in Garment on Body Temperature Responses
3D-Finite Element Analysis for Influences of PCM Inserted in Garment on Body Temperature Responses Open
To investigate the influences of the PCM micro-capsules in the garment on the body temperature responses, a mathematical model of heat and moisture transfer in garments inserted PCM micro-capsules is developed. The model is solved by the f…