Jie Chen
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View article: NAD <sup>+</sup> Enhanced Mesenchymal Stromal Cells Effect on Muscle Atrophy by Improving SIRT1‐Mediated Mitochondrial Function via NAMPT
NAD <sup>+</sup> Enhanced Mesenchymal Stromal Cells Effect on Muscle Atrophy by Improving SIRT1‐Mediated Mitochondrial Function via NAMPT Open
Background Sarcopenia contributes to all‐cause mortality in the elderly; however, there is no specific treatment. Mesenchymal stromal cells (MSCs) ameliorate age‐related muscle loss and dysfunction and are potential therapeutic candidates …
View article: Identification and validation of key mitophagy-related biomarkers in the pathogenesis of proliferative diabetic retinopathy
Identification and validation of key mitophagy-related biomarkers in the pathogenesis of proliferative diabetic retinopathy Open
Introduction Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus, and proliferative diabetic retinopathy (PDR) represents its advanced stage. The etiology of PDR is complex. Mitophagy, the s…
View article: Plant-derived extracellular vesicles: composition, function and clinical potential
Plant-derived extracellular vesicles: composition, function and clinical potential Open
As membrane structural bodies secreted by cells, extracellular vesicles (EVs) have become a hot topic in the field of plant science in recent years. Plant-derived extracellular vesicles (PDEVs) play a key role in both plant physiological a…
View article: Magnetic Seizure Therapy vs Electroconvulsive Therapy in Schizophrenia: Prefrontal-Amygdala Plasticity and Cognitive Safety
Magnetic Seizure Therapy vs Electroconvulsive Therapy in Schizophrenia: Prefrontal-Amygdala Plasticity and Cognitive Safety Open
As the first RCT mapping neuroanatomical changes of convulsive therapies in schizophrenia, we establish MST's cognitive safety via prefrontal-amygdala plasticity-a novel mechanism preserving language and memory functions.
View article: Ferric Oxide Nanoparticles Foliar Application Effectively Enhanced Iron Bioavailability and Rice Quality in Rice (Oryza sativa L.) Grains
Ferric Oxide Nanoparticles Foliar Application Effectively Enhanced Iron Bioavailability and Rice Quality in Rice (Oryza sativa L.) Grains Open
Synergizing iron nutrition and rice quality is essential for the development of integrated high-quality rice. In this study, a two-year field experiment was conducted to investigate the influence of ferric oxide nanoparticles (Fe2O3 NPs) f…
View article: Zinc Oxide Nanoparticles Enhance Grain Yield and Nutritional Quality in Rice via Improved Photosynthesis and Zinc Bioavailability
Zinc Oxide Nanoparticles Enhance Grain Yield and Nutritional Quality in Rice via Improved Photosynthesis and Zinc Bioavailability Open
Improving rice yield, eating quality, and zinc (Zn) nutrition is crucial to meet the growing demand for high-quality and nutritious food, while zinc itself plays a pivotal role in rice growth and quality formation. In this two-year field s…
View article: Optimally integrating a reservoirs group and a flood detention basin for improving their flood control performance
Optimally integrating a reservoirs group and a flood detention basin for improving their flood control performance Open
Study region: Jingjiang flood detention basin and Three gorges (TG), Shuibuya (SBY) and Geheyan (GHY) reservoirs are located in the midstream and downstream of Changjiang River Basin. These reservoirs as a group and the flood detention bas…
View article: An efficient harvesting strategy for agarwood based on the correlation analysis of resin formation and leaves dynamic changes induced by integrated induction method
An efficient harvesting strategy for agarwood based on the correlation analysis of resin formation and leaves dynamic changes induced by integrated induction method Open
Agarwood is a resin produced by wounded Aquilaria plants. Aquilaria sinensis (Lour.) Gilg is the original plant source of agarwood in China. Formic acid combined with Botryosphaeria rhodina A13 (FAA13) induces the formation of artificial a…
View article: BRD4 Signaling Maintains the Differentiated State of β Cells
BRD4 Signaling Maintains the Differentiated State of β Cells Open
In diabetes, pancreatic β cells degenerate from their mature differentiated state to a dedifferentiated state. BRD4 plays a pivotal role during embryogenesis and cancer development, but its function in modulating β‐cell differentiation rem…
View article: Dietary canthaxanthin improves egg production rate through regulating hepatic lipid metabolism and redox status in indigenous chickens
Dietary canthaxanthin improves egg production rate through regulating hepatic lipid metabolism and redox status in indigenous chickens Open
Oxidative stress during egg production disrupts hepatic lipid metabolism and impairs laying performance in hens. This study investigated the effects of dietary canthaxanthin (CX) supplementation (0, 4, 6, 8, 10 mg/kg) on hepatic histomorph…
View article: Biohacking agarwood: the impact of fire drills and brine on endophytes and metabolites of Aquilaria sinensis
Biohacking agarwood: the impact of fire drills and brine on endophytes and metabolites of Aquilaria sinensis Open
Agarwood is a valuable resinous aromatic substance known to have healing properties. Only plants in the Thymelaeace family, specifically the genera Aquilaria and Gyrinops, produce it to defend themselves from insect, bacterial, and fungal …
View article: Integrated metabolomic and transcriptomic insights into the role of anthocyanin and flavonoid biosynthesis in the pulp coloration mechanisms of Baccaurea ramiflora Lour. (Burmese grape)
Integrated metabolomic and transcriptomic insights into the role of anthocyanin and flavonoid biosynthesis in the pulp coloration mechanisms of Baccaurea ramiflora Lour. (Burmese grape) Open
View article: Presence of Aminoglycoside and β-Lactam-Resistant Pseudomonas aeruginosa in Raw Milk of Cows
Presence of Aminoglycoside and β-Lactam-Resistant Pseudomonas aeruginosa in Raw Milk of Cows Open
Pseudomonas aeruginosa is a ubiquitous environmental bacterium that causes a variety of infections in humans and animals. Although antibiotic resistance in livestock has been extensively documented, continuous surveillance remains crucial …
View article: Ene‐Reductases‐Catalyzed Non‐Natural Reactions
Ene‐Reductases‐Catalyzed Non‐Natural Reactions Open
Flavin‐dependent ene‐reductases (EREDs), members of the Old Yellow Enzyme (OYE) superfamily, are highly efficient biocatalysts primarily known for catalyzing the asymmetric reduction of activated alkenes. Beyond this native function, the c…
View article: Modification of essential factors mediating post-translational processing for high-quality protein expression in Penicillium
Modification of essential factors mediating post-translational processing for high-quality protein expression in Penicillium Open
View article: IDENTIFICACIÓN MOLECULAR Y CULTIVO DE CEPAS SILVESTRES DE Pleurotus spp. DE VERACRUZ, MÉXICO
IDENTIFICACIÓN MOLECULAR Y CULTIVO DE CEPAS SILVESTRES DE Pleurotus spp. DE VERACRUZ, MÉXICO Open
Las especies del género Pleurotus tienen un gran potencial para el cultivo comercial en México; sin embargo, los recursos genéticos de este género aún no se han estudiado de manera integral en el país. Los objetivos del presente estudio fu…
View article: A Nir Fluorescent Probe for Detecting Hg2+ and its Multiple Application in Biological Systems and Environmental Media
A Nir Fluorescent Probe for Detecting Hg2+ and its Multiple Application in Biological Systems and Environmental Media Open
View article: Elucidating the Fundamental Process of Methyl-(5hydroxymethyl) Furan-2-Carboxylate Toxin Biosynthesis in Curvularia lunata Causing Maize Leaf Spot
Elucidating the Fundamental Process of Methyl-(5hydroxymethyl) Furan-2-Carboxylate Toxin Biosynthesis in Curvularia lunata Causing Maize Leaf Spot Open
Maize leaf spot, which is caused by Curvularia lunata (Wakkre) Boedijn, was epidemic in the maize-growing regions of northeastern and northern China in the mid-1990s, where it led to large yield losses. Since then, the epidemic has evolved…
View article: Kinesin‐7 <scp>CENP</scp>‐E mediates centrosome organization and spindle assembly to regulate chromosome alignment and genome stability
Kinesin‐7 <span>CENP</span>‐E mediates centrosome organization and spindle assembly to regulate chromosome alignment and genome stability Open
Chromosome congression and alignment are essential for cell cycle progression and genomic stability. Kinesin‐7 CENP‐E, a plus‐end‐directed kinesin motor, is required for chromosome biorientation, congression and alignment in cell division.…
View article: Metabolomics combined with transcriptomics reveals the accumulation mechanism of the fruit pulp colour of Baccaurea ramiflora Lour
Metabolomics combined with transcriptomics reveals the accumulation mechanism of the fruit pulp colour of Baccaurea ramiflora Lour Open
Baccaurea ramiflora Lour., a wild fruit tree with edible, ornamental, and medicinal qualities. The mechanism behind the color accumulation in its fruit pulp, which can be either pink or milky-white, remains unclear. This study investigates…
View article: The jet-like chromatin structure defines active secondary metabolism in fungi
The jet-like chromatin structure defines active secondary metabolism in fungi Open
Eukaryotic genomes are spatially organized within the nucleus in a nonrandom manner. However, fungal genome arrangement and its function in development and adaptation remain largely unexplored. Here, we show that the high-order chromosome …
View article: Integrated Metabolomic and Transcriptomic Insights into the Role of Anthocyanin and Flavonoid Biosynthesis in the Pulp Coloration Mechanisms of Baccaurea Ramiflora Lour. (Burmese Grape)
Integrated Metabolomic and Transcriptomic Insights into the Role of Anthocyanin and Flavonoid Biosynthesis in the Pulp Coloration Mechanisms of Baccaurea Ramiflora Lour. (Burmese Grape) Open
View article: <i>Trichoderma</i>‐derived emodin competes with <scp>ExpR</scp> and <scp>ExpI</scp> of <i>Pectobacterium carotovorum</i> subsp. <i>carotovorum</i> to biocontrol bacterial soft rot
<i>Trichoderma</i>‐derived emodin competes with <span>ExpR</span> and <span>ExpI</span> of <i>Pectobacterium carotovorum</i> subsp. <i>carotovorum</i> to biocontrol bacterial soft rot Open
BACKGROUND Quorum sensing inhibitors (QSIs) are an emerging control tool that inhibits the quorum sensing (QS) system of pathogenic bacteria. We aimed to screen for potential QSIs in the metabolites of Trichoderma and to explore their inhi…
View article: Foliar Spraying of ZnO Nanoparticles Enhanced the Yield, Quality, and Zinc Enrichment of Rice Grains
Foliar Spraying of ZnO Nanoparticles Enhanced the Yield, Quality, and Zinc Enrichment of Rice Grains Open
Zinc deficiency in rice can lead to reduced nutritional value and taste. This study investigates the potential of zinc oxide nanoparticles (ZnO NPs) as a foliar fertilizer during the jointing stage to improve rice yield, quality, and grain…
View article: Zinc Oxide Nanoparticles Foliar Application Effectively Enhanced Zinc and Aroma Content in Rice (Oryza sativa L.) Grains
Zinc Oxide Nanoparticles Foliar Application Effectively Enhanced Zinc and Aroma Content in Rice (Oryza sativa L.) Grains Open
The search for an effective zinc fertilizer and its application method to effectively increase zinc content and enhance aroma in rice grains is a crucial objective. In this study, a 2-year field plot experiment was conducted to investigate…
View article: Fused expression of Sm1-Chit42 proteins for synergistic mycoparasitic response of Trichoderma afroharzianum on Botrytis cinerea
Fused expression of Sm1-Chit42 proteins for synergistic mycoparasitic response of Trichoderma afroharzianum on Botrytis cinerea Open
View article: Prenatal exposure to organophosphorus pesticides and childhood neurodevelopmental phenotypes
Prenatal exposure to organophosphorus pesticides and childhood neurodevelopmental phenotypes Open
Prenatal exposure to organophosphorus pesticides (OPs) has been associated with different neurodevelopmental outcomes across different cohorts. A phenotypic approach may address some of these differences by incorporating information across…
View article: Preparation of High Water-Soluble Trichoderma Co-Culture Metabolite Powder and Its Effects on Seedling Emergence Rate and Growth of Crops
Preparation of High Water-Soluble Trichoderma Co-Culture Metabolite Powder and Its Effects on Seedling Emergence Rate and Growth of Crops Open
Trichoderma spp. are widely used beneficial microbes in agricultural production; however, the improper carrier choice for Trichoderma agent preparation can alter the effectiveness of Trichoderma fungicides. In this study, the co-culture of…
View article: Nitrogen addition influences fine root growth and mycorrhizal symbiosis formation in trees with contrasting root morphology
Nitrogen addition influences fine root growth and mycorrhizal symbiosis formation in trees with contrasting root morphology Open
Funder: \n http://dx.doi.org/10.13039/501100018647\n RUDN University
View article: Trichoderma and its role in biological control of plant fungal and nematode disease
Trichoderma and its role in biological control of plant fungal and nematode disease Open
Trichoderma is mainly used to control soil-borne diseases as well as some leaf and panicle diseases of various plants. Trichoderma can not only prevent diseases but also promotes plant growth, improves nutrient utilization efficiency, enha…