Yang Wang
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View article: Overcoming Challenges in AAV Plasmid Preparation: Advanced Solutions for Superior ITR Integrity and High-Yield Production 9427
Overcoming Challenges in AAV Plasmid Preparation: Advanced Solutions for Superior ITR Integrity and High-Yield Production 9427 Open
Description AAV-based gene therapies are transforming treatments for genetic disorders, cancer, and rare diseases. However, preparing high-quality AAV plasmids is challenging, particularly in maintaining ITR integrity due to its repetitive…
View article: Overcoming challenges in mRNA plasmid preparation: advanced solutions for Poly(A) tail integrity and high-yield production 9428
Overcoming challenges in mRNA plasmid preparation: advanced solutions for Poly(A) tail integrity and high-yield production 9428 Open
Description The rapid growth of mRNA research is driving breakthroughs in vaccine development, cancer immunotherapy, and regenerative medicine, increasing the demand for high-quality plasmid DNA templates. These templates are crucial for i…
View article: Ultrasensitive and Ultrafast Self‐Powered Ultraviolet Photodetector Array for Solar‐Blind and Weak‐Light Imaging
Ultrasensitive and Ultrafast Self‐Powered Ultraviolet Photodetector Array for Solar‐Blind and Weak‐Light Imaging Open
Self‐powered ultraviolet (UV) photodetectors (PDs) based on wide bandgap semiconductors (WBGSs) and their heterostructures face challenges in ultrasensitive and ultrafast weak‐light detection capabilities. In this work, an 8 × 8 UV photode…
View article: A facile construction of LiF interlayer and F-doping via PECVD for LATP-based hybrid electrolytes: Enhanced Li-ion transport kinetics and superior lithium metal compatibility
A facile construction of LiF interlayer and F-doping via PECVD for LATP-based hybrid electrolytes: Enhanced Li-ion transport kinetics and superior lithium metal compatibility Open
View article: Unlocking azobenzene isomerization mechanisms via an LLM agent-driven workflow integrating simulation, experiment, and machine learning
Unlocking azobenzene isomerization mechanisms via an LLM agent-driven workflow integrating simulation, experiment, and machine learning Open
Bridged azobenzene derivatives are important photo-responsive molecular switches with wide-ranging applications in optoelectronics and information storage, owing to their reversible isomerization around the –N=N– bond. However, elucidating…
View article: Constructing vertical Li+ transport “Highways” and interface regulation of composite solid electrolytes for ultra-stable lithium metal batteries
Constructing vertical Li+ transport “Highways” and interface regulation of composite solid electrolytes for ultra-stable lithium metal batteries Open
View article: Development of a magnesium silicate nanotube coating for enhanced zinc-ion transport in dendrite-free zinc anodes
Development of a magnesium silicate nanotube coating for enhanced zinc-ion transport in dendrite-free zinc anodes Open
View article: Pharmacological mechanisms of Nelumbinis plumula for insomnia: validation of key active ingredients and target pathways
Pharmacological mechanisms of Nelumbinis plumula for insomnia: validation of key active ingredients and target pathways Open
Background Nelumbinis plumula (Lianzixin) is a traditional Chinese medicine with sedative and hypnotic properties. Our previous study discovered that natural bisbenzylisoquinoline alkaloids from Nelumbinis plumula exhibit good binding affi…
View article: Unconventional Topological Weyl Dipole Phonon
Unconventional Topological Weyl Dipole Phonon Open
A pair of Weyl points (WPs) with opposite topological charges can exhibit an additional higher‐order Z 2 topological charge, giving rise to the formation of a Z 2 Weyl dipole (WD). Owing to the nontrivial topological charge, Z 2 WDs should…
View article: Association between exposure to blood heavy metal mixtures and overactive bladder risk among U.S. adults: a cross-sectional study
Association between exposure to blood heavy metal mixtures and overactive bladder risk among U.S. adults: a cross-sectional study Open
Background Increasing evidence has demonstrated that exposure to environmental heavy metals harms human health. However, information regarding the impact of co-exposure to metal mixtures on the risk of overactive bladder (OAB) was limited.…
View article: Metal-like behavior of a 2D molecular catalyst enables redox-decoupled electrocatalysis
Metal-like behavior of a 2D molecular catalyst enables redox-decoupled electrocatalysis Open
Molecular catalysts facilitate electrochemical conversion by changing their oxidation states to transfer electrons. However, this redox-mediated mechanism features stepwise electron transfer and substrate activation in separate elementary …
View article: A Ba<sub>0.5</sub>Sr<sub>0.5</sub>TiO<sub>3</sub> Interlayer Enabling Ultra‐Stable Performance in Hybrid Solid–Liquid Lithium Metal Batteries
A Ba<sub>0.5</sub>Sr<sub>0.5</sub>TiO<sub>3</sub> Interlayer Enabling Ultra‐Stable Performance in Hybrid Solid–Liquid Lithium Metal Batteries Open
Li 1.3 Al 0.3 Ti 1.7 (PO 4 ) 3 (LATP) is a promising solid‐state electrolyte for next‐generation solid‐state lithium metal batteries, offering high ionic conductivity, superior air stability, and low cost. However, its practical applicatio…
View article: Prism: Unleashing GPU Sharing for Cost-Efficient Multi-LLM Serving
Prism: Unleashing GPU Sharing for Cost-Efficient Multi-LLM Serving Open
Serving large language models (LLMs) is expensive, especially for providers hosting many models, making cost reduction essential. The unique workload patterns of serving multiple LLMs (i.e., multi-LLM serving) create new opportunities and …
View article: Flexible Gas Sensor Based on PANI/WO3/CuO for Room-Temperature Detection of H2S
Flexible Gas Sensor Based on PANI/WO3/CuO for Room-Temperature Detection of H2S Open
Polyaniline (PANI) is currently one of the most extensively studied conductive polymers in the field of flexible gas sensors. However, sensors based on pure PANI generally suffer from problems such as low sensitivity and poor stability. To…
View article: Structural Insights into an Antiparallel Chair‐Type G‐Quadruplex From the Intron of <i>NOP56</i> Oncogene
Structural Insights into an Antiparallel Chair‐Type G‐Quadruplex From the Intron of <i>NOP56</i> Oncogene Open
G‐quadruplex (G4) structures play important roles in various biological processes, especially the gene regulation. Nucleolar protein 56 (NOP56) is an essential component in ribosome biogenesis while its overexpression associates with vario…
View article: Facile fabrication of Cu single atoms by utilizing nano-constrained environment
Facile fabrication of Cu single atoms by utilizing nano-constrained environment Open
View article: Unconventional topological Weyl-dipole phonon
Unconventional topological Weyl-dipole phonon Open
A pair of Weyl points (WPs) with opposite Chern numbers ${\cal{C}}$ can exhibit an additional higher-order $Z_2$ topological charge, giving rise to the formation of a $Z_2$ Weyl dipole. Owing to the nontrivial topological charge, $Z_2$ Wey…
View article: Resveratrol-loaded metal-organic framework for mitochondria-targeted amplified CO gas therapy
Resveratrol-loaded metal-organic framework for mitochondria-targeted amplified CO gas therapy Open
Carbon monoxide (CO) based gas therapy has recently garnered significant attention due to its remarkable therapeutic effects for various major diseases. However, the primary challenge in gas therapy is the effective delivery of gas prodrug…
View article: Study on the Mechanism of Photocatalytic Degradation of Tetracycline Hydrochloride by Zr-Doped Bi24o31cl10
Study on the Mechanism of Photocatalytic Degradation of Tetracycline Hydrochloride by Zr-Doped Bi24o31cl10 Open
View article: Cobalt-Aluminum Layered Double Hydroxides Activated Sodium Percarbonate for Efficient Degradation of Tetracycline Hydrochloride: Performance, Mechanism, and Stability
Cobalt-Aluminum Layered Double Hydroxides Activated Sodium Percarbonate for Efficient Degradation of Tetracycline Hydrochloride: Performance, Mechanism, and Stability Open
View article: Study on the Mechanism of Bi2wo6/ Nixmo1-Xs2 Heterojunction Photocatalysis for Efficient Degradation of Tch
Study on the Mechanism of Bi2wo6/ Nixmo1-Xs2 Heterojunction Photocatalysis for Efficient Degradation of Tch Open
View article: Study on the Mechanism of Bi2wo6/ Nixmo1-Xs2 Heterojunction Photocatalysis for Efficient Degradation of Tch
Study on the Mechanism of Bi2wo6/ Nixmo1-Xs2 Heterojunction Photocatalysis for Efficient Degradation of Tch Open
View article: Study on the Effects of Pyrolysis Temperature and Feedstock Ratio on the Performance and Mechanism of Pine Sawdust–Lignin Derived Bio-Coke
Study on the Effects of Pyrolysis Temperature and Feedstock Ratio on the Performance and Mechanism of Pine Sawdust–Lignin Derived Bio-Coke Open
View article: Enhanced Photocatalytic Degradation of Tetracycline Hydrochloride by Zr-Doped Bi24O31Cl10: Synthesis, Characterization, and Reaction Mechanism
Enhanced Photocatalytic Degradation of Tetracycline Hydrochloride by Zr-Doped Bi24O31Cl10: Synthesis, Characterization, and Reaction Mechanism Open
View article: Cobalt-Aluminum Layered Double Hydroxides Activated Sodium Percarbonate for Efficient Degradation of Tetracycline Hydrochloride: Performance, Mechanism, and Stability
Cobalt-Aluminum Layered Double Hydroxides Activated Sodium Percarbonate for Efficient Degradation of Tetracycline Hydrochloride: Performance, Mechanism, and Stability Open
View article: Study on the mechanism of Bi2WO6/ NixMo1-xS2 heterojunction photocatalysis for efficient degradation of TCH
Study on the mechanism of Bi2WO6/ NixMo1-xS2 heterojunction photocatalysis for efficient degradation of TCH Open
View article: One-Step Hard-Templated Synthesis of Ordered Mesoporous Carbon/WO3 Composites with Synergistically Enhanced Photocatalytic Activity for Efficient Rhodamine B Degradation
One-Step Hard-Templated Synthesis of Ordered Mesoporous Carbon/WO3 Composites with Synergistically Enhanced Photocatalytic Activity for Efficient Rhodamine B Degradation Open
View article: DNA methylation confers a cerebellum-specific identity in non-human primates
DNA methylation confers a cerebellum-specific identity in non-human primates Open
Selective regulation of gene expression across distinct brain regions is crucial for establishing and maintaining subdivision identities. DNA methylation, a key regulator of gene transcription, modulates transcriptional activity through th…
View article: Spatial distribution characteristics, ecological risk assessment, and source analysis of heavy metal(loid)s in surface sediments of the nearshore area of Qionghai
Spatial distribution characteristics, ecological risk assessment, and source analysis of heavy metal(loid)s in surface sediments of the nearshore area of Qionghai Open
To understand the pollution characteristics and potential sources of heavy metal(loid)s in the nearshore sediments of Qionghai, 93 surface sediment samples were collected from the region. The concentrations of 20 elements, including Fe, Mg…
View article: Study on Evaluation of Fruit Aroma of Plum Variety Resources Based on Headspace Solid-Phase Microextraction Combined with Gas Chromatography–Mass Spectrometry
Study on Evaluation of Fruit Aroma of Plum Variety Resources Based on Headspace Solid-Phase Microextraction Combined with Gas Chromatography–Mass Spectrometry Open
To explore the characteristics of and variations in aroma components across different plum varieties and maturity stages, this study employed headspace solid-phase microextraction combined with gas chromatography–mass spectrometry (HS-SPME…