Explanipedia

Unsupervised clustering of RNA sequencing data identifies a novel XBP1-mutated subtype of B-cell acute lymphoblastic leukemia (B-ALL) Open

Qian Jiang, Jianfeng Yao, Jianfeng Zhou · 2025

1. Research Objectives :With the application of RNA sequencing (RNA-seq) in B-ALL, the diagnosis of B-ALL has entered the era of precision molecular diagnostics. Despite almost 90% of newly diagnosed B-ALL cases can be diagnosed as the def…

Placebo effect of sham acupuncture in patients with insomnia and influence of varying stimulation intensities and locations: A systematic review and meta-analysis Open

Junpeng Chi, Ruixin Zhu, Cheng Chen, Rui‐Hua Xu, Cuicui Lyu , et al. · 2025

Sham acupuncture produces a measurable and relatively stable placebo effect in insomnia patients. The effectiveness varied across different sham protocols, with low-intensity stimulation and medium-frequency regimens (13-20 sessions) showi…

Dry period heat tolerance affects placental efficiency, apoptosis, and protein expression in Holstein cows Open

Xiaoli Chen, Chun Li, Ting Fang, Jianfeng Yao, Xiaowei Gu · 2025

The placenta plays a key role in fetal growth and functions to transport nutrients that are vital to the fetus. Heat stress (HS) impairs placental function in cows, affecting fetal development. There is limited information on the effects o…

Association between the neutrophil-to-high-density lipoprotein cholesterol ratio with kidney stone risk: a cross-sectional study Open

Yuan-Zhuo Du, Jian Yang, Jianfeng Yao, Chi-Teng Zhang, Yifu Liu · 2025

Objective Kidney stones are a major issue for public health worldwide. Discovering potential clues in identifying at-risk individuals is essential for early detection and timely treatment. This study explores the relationship of the neutro…

Is Parameter Collision Hindering Continual Learning in LLMs? Open

Shuo Yang, Kun-Peng Ning, Yuyang Liu, Jianfeng Yao, Y. Tian , et al. · 2024

Large Language Models (LLMs) often suffer from catastrophic forgetting when learning multiple tasks sequentially, making continual learning (CL) essential for their dynamic deployment. Existing state-of-the-art (SOTA) methods, such as O-Lo…

Microbial Disruptions in Inflammatory Bowel Disease: A Comparative Analysis Open

Jianxia Ma, Ke Wang, Jun Wang, Qinlian Zeng, Kangwei Liu , et al. · 2024

There is intestinal microbiota imbalance in IBD patients, and the abundance of Roseburia, Coprococcus and Ruminiclostridium is reduced significantly in the active period of IBD, which may be related to the active IBD.

A Swarm Intelligence Enabled Reinforcement Learning Approach for Computational Task Offloading in Internet of Things Blockchain Open

Zhuo Chen, Jiahuan Yi, Xiaofei Zhu, Qingyang Wang, Jianfeng Yao , et al. · 2024

DAG-based swarm learning: A secure asynchronous learning framework for Internet of Vehicles Open

Xiaoge Huang, Hongbo Yin, Qianbin Chen, Yu Zeng, Jianfeng Yao · 2023

To provide diversified services in the intelligent transportation systems, smart vehicles will generate unprecedented amounts of data every day. Due to data security and user privacy issues, Federated Learning (FL) is considered a potentia…

A Design of Tree Micro Drill Instrument to Improve the Accuracy of Wood Density Measurement Open

Jianfeng Yao, Zhenyang Wu, Yili Zheng, Benqiang Rao, Zhuofan Li , et al. · 2023

To improve the measurement accuracy of wood density and study the linear correlation between the drill feed resistance and wood density, a new micro drill instrument that can can simultaneously measure the rotation resistance and feed resi…

Investigating the Resistance Expression Method of Wood Resistance Drill Instruments Open

Jianfeng Yao, Jun Lü, Xilong Ding · 2023

Wood density is an important attribute that is positively correlated with many wood quality parameters. How to express wood density with drill resistance is a challenge. In this study, we determined the optimal resistance expression using …

Influence of Flax Seeds on the Gut Microbiota of Elderly Patients with Constipation Open

Jianxia Ma, Jianqin Sun, Huijing Bai, Houlian Ma, Ke Wang , et al. · 2022

Flax seeds may improve the defecation in elderly patients with chronic constipation and change intestinal microecological structure. Thus, flax seeds may serve as an effective diet supplement in the management of chronic constipation.

Table of Contents Open

Xiaoman Hu, Yonggang Peng, Haojie Mo, Tiantian Cai, Qingtang Deng , et al. · 2022

Is preterm donor milk better than preterm formula for very-low-birth-weight infants? Open

Lingyu Fang, Zhang Mei-li, Lianqiang Wu, Ruiquan Wang, Bangbang Lin , et al. · 2021

The study indicated that preterm DM does not affect the growth of very-low-birth-weight infants. Further, it significantly reduces feeding intolerance, helps achieve full enteral feeding early, and has protective effects against necrotizin…

Hypoxia-dependent expression of MAP17 coordinates the Warburg effect to tumor growth in hepatocellular carcinoma Open

Fangyuan Dong, Rongkun Li, Jiaofeng Wang, Yan Zhang, Jianfeng Yao , et al. · 2021

Effects of Danggui injection combined with sodium hyaluronate injection on expression of inflammatory factors and BC-L2 RNA and BaxRNA in chondrocytes of rabbit model of knee osteoarthritis Open

Ziyi Liang, Bo Dong, Z. Wang, P. Yuan, W. Kang , et al. · 2021

Observation on the therapeutic effect of kangshuqianggu prescription on mice with castrated osteoporosis Open

T. Wang, Bin Dong, Jianfeng Yao, P. Yuan, Z. Wang , et al. · 2021

Clinical efficacy of warm acupuncture in the treatment of knee osteoarthritis (cold-damp paralysis) and its effect on pain level Open

Bo Dong, Heng Yin, P. Yuan, Jianfeng Yao, Z. Wang , et al. · 2021

[Autologous versus unrelated donor stem cell transplantation for adults with primary acute myeloid leukemia in first remission]. Open

Jianfeng Yao, G X Zhang, Daiyu Yang, Yi He, Jialiu Wei , et al. · 2020

Objective: To compare differences of autologous and unrelated donor stem cell transplantation (auto-HSCT and URD-HSCT) for adults with primary acute myeloid leukemia (AML) in first complete remission (CR(1)) from a single center and…

The Composition of Intestinal Microbiota and its Association with Functional Constipation of the Elderly Patients Open

Mingquan Guo, Jianfeng Yao, Feng Yang, Wenjian Liu, Huijing Bai , et al. · 2020

Aim: To identify intestinal microbiota compositions in elderly functional constipation (FC) patients. Materials & methods: Fecal samples from 61 FC patients and 48 healthy age-matched volunteers were analyzed through 16S rRNA…

Effects of Vitrification on the Imprinted Gene Snrpn in Neonatal Placental Tissue Open

Jianfeng Yao, Yanfang Huang, Rongfu Huang, Suxia Lin, Cai-Qiong Guo , et al. · 2020

Objective: To investigate the effects of vitrification on the expression of the imprinted gene Snrpn in neonatal placental tissue.Methods: Neonatal placental tissue was collected from women with natural pregnancy (control group) and from w…

Pre-transplant cytoreductive therapy can improve overall survival of patients with MDS-AML but not MDS-EB2 receiving HLA-matched sibling donor peripheral blood stem cell transplantation. Open

Qianqian Wang, Xingli Zhao, Zixian Liu, Xiaoli Zhao, Guixin Zhang , et al. · 2020

To evaluate whether cytoreductive therapy is needed for myelodysplastic syndromes (MDS) patients with excess blasts type 2 (MDS-EB2) and acute myeloid leukemia derived from MDS (MDS-AML) before HLA-matched sibling donor peripheral blood st…

Bone Marrow-Derived Mesenchymal Stem Cells Modified with Akt1 Ameliorates Acute Liver GVHD Open

Lukun Zhou, Shuang Liu, Zhao Wang, Jianfeng Yao, Wenbin Cao , et al. · 2019

Graphical Abstract: Angew. Chem. Int. Ed. 39/2019 Open

David Chen, Yu-Kai David, Søbastien Vidal, Carolyn R. Bertozzi, Hongna Liu , et al. · 2019

from GDCh, Postfach 900440, D-60444 Frankfurt am Main, Germany.

Differential expression of miR‑4492 and IL‑10 is involved in chronic rhinosinusitis with nasal polyps Open

Linge Li, Juan Feng, Dinghao Zhang, Jun Yong, Yan Wang , et al. · 2019

Chronic rhinosinusitis (CRS) is one of the most common types of respiratory disease and affects a large proportion of the population worldwide. The clinical differences between CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (C…

[HLA-10/10 matched unrelated donor versus sibling donor hematopoietic stem cell transplantation for adult acute myeloid leukemia]. Open

Jianfeng Yao, G X Zhang, Y Y Shen, R L Zhang, Yi He , et al. · 2019

Objective: To evaluate the outcomes of human leukocyte antigen (HLA) matched unrelated donor hematopoietic stem cell transplantation (MUD-HSCT) for adult acute myeloid leukemia (AML) in a single center. Methods: Consecutive a…

Circadian Clock Genes in the Metabolism of Non-alcoholic Fatty Liver Disease Open

Dongmei Shi, Jie Chen, Jiaofeng Wang, Jianfeng Yao, Yiqin Huang , et al. · 2019

Non-alcoholic fatty liver disease (NAFLD) is a common disease, which is characterized by the accumulation of triglycerides in the hepatocytes without excess alcohol intake. Circadian rhythms can participate in lipid, glucose, and cholester…

To explore the molecular mechanism of kidney-tonifying and blood-activating method in the prevention and treatment of postmenopausal osteoporosis based on cAMP-PKA-CREB signaling pathway Open

R. Chen, Bin Dong, Jianfeng Yao, G. Ou, Mengyuan Li , et al. · 2019

Histomorphological observation of rat model of knee osteoarthritis by liuwei dihuang decoction Open

Gong Yang, Jianfeng Yao, Bo Dong, R. Chen · 2019

Experimental study on the intervention of renal tonifying and activating OPG/RANKL/RANK signaling pathway on steroid-induced femoral head necrosis Open

Bo Dong, Jianfeng Yao, X. Li, Hongbo Yu, W. Kang , et al. · 2019

Role of HGF/c‐Met in the treatment of colorectal cancer with liver metastasis Open

Jianfeng Yao, Xiaojun Li, Likun Yan, Sai He, Jianbao Zheng , et al. · 2019

The system of hepatocyte growth factor (HGF) and its receptor c‐Met plays a critical role in tumor invasive growth and metastasis. The mortality rate of colorectal cancer (CRC), one of the most commonly diagnosed malignancies, is increased…

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