Jianbo An
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View article: ACE2-like enzyme B38-CAP suppresses abdominal sepsis and severe acute lung injury
ACE2-like enzyme B38-CAP suppresses abdominal sepsis and severe acute lung injury Open
Angiotensin-converting enzyme 2 (ACE2) is the carboxypeptidase to degrade angiotensin II (Ang II) to angiotensin 1–7 (Ang 1–7) and improves the pathologies of cardiovascular disease and acute respiratory distress syndrome (ARDS)/acute lung…
View article: Peritumoral CD16b positive-neutrophil accumulation strongly correlates with regional lymph node metastasis in thoracic esophageal squamous cell cancer
Peritumoral CD16b positive-neutrophil accumulation strongly correlates with regional lymph node metastasis in thoracic esophageal squamous cell cancer Open
Peritumoral accumulation of CD16b-positive neutrophils is an independent factor strongly correlated with lymph node metastasis in thoracic esophageal squamous cell cancer.
View article: Therapeutic effects of angiotensin converting enzyme 2 (ACE2) enzyme activity on acute lung injury in COVID-19
Therapeutic effects of angiotensin converting enzyme 2 (ACE2) enzyme activity on acute lung injury in COVID-19 Open
Angiotensin-converting enzyme 2 (ACE2) is a receptor for cell entry of SARS-CoV-2, and recombinant soluble ACE2 protein inhibits SARS-CoV-2 infection as a decoy. ACE2 is a carboxypeptidase that degrades angiotensin II (Ang II) and thereby …
View article: Upregulation of Galectin-7 in specific tumor microenvironment contributes to squamous cell carcinoma metastasis
Upregulation of Galectin-7 in specific tumor microenvironment contributes to squamous cell carcinoma metastasis Open
Metastasis predicts poor prognosis in patients with esophageal squamous cell carcinoma, whereas the regulatory mechanism of metastasis remains largely unknown. In this study, by using murine tumor metastasis model and spatial transcriptome…
View article: Spatial transcriptome analysis revealed novel regulatory mechanism of tumor metastasis
Spatial transcriptome analysis revealed novel regulatory mechanism of tumor metastasis Open
Metastasis predicts poor prognosis in patients with esophageal squamous cell carcinoma, whereas the regulatory mechanism of metastasis remains largely unknown. In this study, by using murine tumor metastasis model and spatial transcriptome…
View article: ACE2-like carboxypeptidase B38-CAP suppresses severe acute lung injury induced by aspiration pneumonia and abdominal sepsis as well as SARS-CoV-2 infection
ACE2-like carboxypeptidase B38-CAP suppresses severe acute lung injury induced by aspiration pneumonia and abdominal sepsis as well as SARS-CoV-2 infection Open
Angiotensin-converting enzyme 2 (ACE2) is the carboxypeptidase to degrade angiotensin II (Ang II) to angiotensin 1–7 (Ang 1–7) and improves the pathologies of cardiovascular disease and acute respiratory distress syndrome (ARDS) / acute lu…
View article: ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury
ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury Open
View article: ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury
ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury Open
Angiotensin-converting enzyme 2 (ACE2) is a receptor for cell entry of SARS-CoV-2, and recombinant soluble ACE2 protein inhibits SARS-CoV-2 infection as a decoy. ACE2 is a carboxypeptidase that degrades angiotensin II (Ang II) to angiotens…
View article: Suppression of SARS-CoV-2-induced lung injury by ACE2-like carboxypeptidase B38-CAP in COVID-19 mouse model
Suppression of SARS-CoV-2-induced lung injury by ACE2-like carboxypeptidase B38-CAP in COVID-19 mouse model Open
Angiotensin-converting enzyme 2 (ACE2) is a receptor for cell entry of SARS-CoV-2, and recombinant soluble ACE2 protein inhibits SARS-CoV-2 infection as a decoy. ACE2 is the carboxypeptidase to degrade angiotensin II (Ang II) to angiotensi…
View article: ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury
ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury Open
Angiotensin-converting enzyme 2 (ACE2) is a receptor for cell entry of SARS-CoV-2, and recombinant soluble ACE2 protein inhibits SARS-CoV-2 infection as a decoy. ACE2 is the carboxypeptidase to degrade angiotensin II (Ang II) to angiotensi…
View article: Dissecting the role of CNOT6L deadenylase in pressure overload-induced cardiac fibrosis
Dissecting the role of CNOT6L deadenylase in pressure overload-induced cardiac fibrosis Open
Heart failure is a leading cause of death in developed countries. The role of mRNA regulation in the pathology of heart failure remains elusive. CCR4-NOT complex is a multi-subunit protein complex constituting exonuclease-mediated degradat…
View article: MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages
MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages Open
Atherosclerosis often results in high incidence of vascular occlusion and has been recognized as the major cause of coronary artery disease. We had previously reported that promoter polymorphism of myocardin-related transcription factor A …
View article: Probiotic Bacillus amyloliquefaciens C-1 Improves Growth Performance, Stimulates GH/IGF-1, and Regulates the Gut Microbiota of Growth-Retarded Beef Calves
Probiotic Bacillus amyloliquefaciens C-1 Improves Growth Performance, Stimulates GH/IGF-1, and Regulates the Gut Microbiota of Growth-Retarded Beef Calves Open
Growth retardation of calves is defined as a symptom of impaired growth and development, probably due to growth hormone disorder as well as natural and environmental factors in livestock. The growth-promoting effects of probiotics were det…
View article: MKL1 expressed in macrophages contributes to the development of murine colitis
MKL1 expressed in macrophages contributes to the development of murine colitis Open
View article: Pre-miR-149 rs71428439 polymorphism is associated with increased cancer risk and AKT1/cyclinD1 signaling in hepatocellular carcinoma.
Pre-miR-149 rs71428439 polymorphism is associated with increased cancer risk and AKT1/cyclinD1 signaling in hepatocellular carcinoma. Open
Hepatocellular carcinoma (HCC) is one of the most common lethal malignancies in the world, and the current knowledge on the molecular and genetic basis of HCC is still limited. Previous study has shown miR-149 plays a tumor suppressive rol…