Jie Xu
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View article: Rationale and design of a PROBE trial comparing continuous enteral nutrition to time-restricted enteral nutrition in severe stroke
Rationale and design of a PROBE trial comparing continuous enteral nutrition to time-restricted enteral nutrition in severe stroke Open
Background and purpose Continuous enteral nutrition treatment is routinely provided in the intensive care unit (ICU) for patients with critically ill stroke and contributes to circadian rhythm disruption because a time-limited diet is part…
View article: Lp(a) levels and ischemic stroke recurrence in type 2 diabetes mellitus
Lp(a) levels and ischemic stroke recurrence in type 2 diabetes mellitus Open
Both low and high levels of Lp(a) are associated with an increased risk of stroke recurrence in T2DM patients with a recent history of acute ischemic stroke or TIA, demonstrating a U-shaped relationship.
View article: Hesperetin as a potent antiviral agent against channel catfish virus by interfering with viral internalization and early replication
Hesperetin as a potent antiviral agent against channel catfish virus by interfering with viral internalization and early replication Open
View article: Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis
Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis Open
Carotid atherosclerosis (CAS) is a major contributor to ischemic stroke, with vascular calcification driving disease progression. However, the molecular mechanisms driving vascular calcification in CAS remain unelucidated. Previous studies…
View article: Therapeutic efficacy of acupuncture on motor dysfunction in ischemic stroke patients with hemiplegia and its EEG characteristics: protocol for a randomized, sham-acupuncture controlled, assessor-and-statistician-blinded trial
Therapeutic efficacy of acupuncture on motor dysfunction in ischemic stroke patients with hemiplegia and its EEG characteristics: protocol for a randomized, sham-acupuncture controlled, assessor-and-statistician-blinded trial Open
Background Stroke is the second leading cause of death in the world, with high disability rate in survivors, among which ischemic stroke accounts for over 80% of the total. Limb dysfunction is a common neurological deficit symptom left by …
View article: Association between A Body Shape Index and Frailty in Older US Adults: The Mediating Role of Physical Activity and Machine Learning-Based Prediction
Association between A Body Shape Index and Frailty in Older US Adults: The Mediating Role of Physical Activity and Machine Learning-Based Prediction Open
Background Frailty is a common syndrome in the elderly population, significantly impacting their quality of life and prognosis. A Body Shape Index (ABSI), as a novel body shape index reflecting body fat distribution, has recently gained at…
View article: Glia maturation factor-β deficiency improves insulin resistance by promoting CARM1-mediated lipid turnover
Glia maturation factor-β deficiency improves insulin resistance by promoting CARM1-mediated lipid turnover Open
View article: Algebras, Entanglement Islands, and Observers
Algebras, Entanglement Islands, and Observers Open
Some recent work has postulated the existence of an "observer" for a consistent definition of subregion algebras in gravitational universes. The subregion algebras consist of operators dressed to this "observer" and are typically Type II v…
View article: Correction: Endovascular Treatment in Patients with Large Vessel Occlusion Stroke of Different Mechanisms
Correction: Endovascular Treatment in Patients with Large Vessel Occlusion Stroke of Different Mechanisms Open
View article: Axial length as a predictor of myopic macular degeneration: a meta-analysis and clinical study
Axial length as a predictor of myopic macular degeneration: a meta-analysis and clinical study Open
Purpose This study aims to investigate the relationship between axial length (AL) and the severity of myopic macular degeneration (MMD). Methods We conducted a comprehensive search of PubMed, Web of Science, and China National Knowledge In…
View article: Endovascular Treatment in Patients with Large Vessel Occlusion Stroke of Different Mechanisms
Endovascular Treatment in Patients with Large Vessel Occlusion Stroke of Different Mechanisms Open
The functional outcomes of patients with AIS-LVO were similar among different mechanisms, despite the sICH being much higher in patients with AAE. The optimal management for AIS-LVO with different mechanisms requires further research.
View article: Association between body roundness index and frailty in older Americans: a cross-sectional study of NHANES 2007–2018
Association between body roundness index and frailty in older Americans: a cross-sectional study of NHANES 2007–2018 Open
This study used NHANES data from 2007 to 2018 to examine the relationship between frailty and the Body Roundness Index (BRI) in U.S. people 60 years of age and older. BRI = 364.2–365.5 × sqrt [1–(wc/2π) 2 /(Height/2) 2 ]. The degree of fra…
View article: Dose–response relationship and predictive value of soluble <scp>B7</scp>‐<scp>DC</scp> in bronchoalveolar lavage fluid and risk of refractory Mycoplasma pneumoniae pneumonia in children
Dose–response relationship and predictive value of soluble <span>B7</span>‐<span>DC</span> in bronchoalveolar lavage fluid and risk of refractory Mycoplasma pneumoniae pneumonia in children Open
This study was to investigate the clinical significance of soluble B7‐dendritic cell (sB7‐DC) concentration in bronchoalveolar lavage fluid (BALF) of children with Refractory Mycoplasma pneumoniae pneumonia (RMPP). A total of 298 patients …
View article: Edaravone Dexborneol vs Placebo on Functional Outcomes in Patients with Acute Ischaemic Stroke Who Underwent Endovascular Thrombectomy (Taste-2): A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial
Edaravone Dexborneol vs Placebo on Functional Outcomes in Patients with Acute Ischaemic Stroke Who Underwent Endovascular Thrombectomy (Taste-2): A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Open
View article: Development of an Improved Stacked U-Net Model for Cuffless Blood Pressure Estimation Based on PPG Signals
Development of an Improved Stacked U-Net Model for Cuffless Blood Pressure Estimation Based on PPG Signals Open
Goal: This study presents an enhanced stacked U-Net deep learning model for cuffless blood pressure estimation using only photoplethysmogram signals, aiming to improve the accuracy of non-invasive measurements. Methods: To ad…
View article: Association between trimethylamine N-oxide and prognosis of patients with myocardial infarction: a meta-analysis
Association between trimethylamine N-oxide and prognosis of patients with myocardial infarction: a meta-analysis Open
Background Trimethylamine N-oxide (TMAO) has been widely explored and considered as a biomarker for adverse cardiovascular events. However, the relationships between TMAO adverse cardiovascular events are inconsistent in patients. Therefor…
View article: Adhesive chitosan-based hybrid biohydrogels for peripheral nerve injury repair
Adhesive chitosan-based hybrid biohydrogels for peripheral nerve injury repair Open
With the rapid progress of industrialization, the incidence of peripheral nerve injuries caused by trauma has been continuously increasing. These injuries result in a significant number of disabilities and irreversible functional impairmen…
View article: Beyond low-density lipoprotein cholesterol levels: Impact of prior statin treatment on ischemic stroke outcomes
Beyond low-density lipoprotein cholesterol levels: Impact of prior statin treatment on ischemic stroke outcomes Open
View article: Molecular mechanism of the influence of related genes expression in synoviumtissue around shoulder joint of secondary frozen shoulder model rats onangiogenesis
Molecular mechanism of the influence of related genes expression in synoviumtissue around shoulder joint of secondary frozen shoulder model rats onangiogenesis Open
The study aimed to explore the pathogenesis of secondary frozen shoulder and its influence on synovium tissue and angiogenesis by constructing a rat secondary frozen shoulder model along with transforming growth factor. 40 healthy male rat…
View article: The association between dietary vitamin B1 intake and constipation: a population-based study
The association between dietary vitamin B1 intake and constipation: a population-based study Open
Background Numerous researches have indicated a correlation between the intake of dietary micronutrients and the occurrence of constipation. Nevertheless, the correlation between constipation and vitamin B1 remains uninvestigated. The main…
View article: LDL-C Levels and Bleeding Risk in Patients Taking DAPT After Minor Ischemic Stroke or TIA
LDL-C Levels and Bleeding Risk in Patients Taking DAPT After Minor Ischemic Stroke or TIA Open
Importance Evidence on the bleeding risk associated with low-density lipoprotein cholesterol (LDL-C) levels in patients receiving dual antiplatelet therapy (DAPT) remains sparse. Objective To investigate the association of LDL-C levels wit…
View article: The next‐generation therapies in ophthalmology for blindness worldwide
The next‐generation therapies in ophthalmology for blindness worldwide Open
With the rapid and groundbreaking development in 21st century medicine on a global scale, new possibilities have emerged for addressing eye diseases, that can be blindness, and that conventional pharmaceuticals and surgical interventions h…
View article: Hemodynamic changes in progressive cerebral infarction: An observational study based on blood pressure monitoring
Hemodynamic changes in progressive cerebral infarction: An observational study based on blood pressure monitoring Open
Progressive cerebral infarction (PCI) is a common complication in patients with ischemic stroke that leads to poor prognosis. Blood pressure (BP) can indicate post‐stroke hemodynamic changes which play a key role in the development of PCI.…
View article: Kaempferol is a novel antiviral agent against channel catfish virus infection through blocking viral attachment and penetration in vitro
Kaempferol is a novel antiviral agent against channel catfish virus infection through blocking viral attachment and penetration in vitro Open
Channel catfish virus (CCV, Ictalurid herpesvirus 1) is the causative pathogen of channel catfish virus disease, which has caused high mortality and substantial economic losses in the catfish aquaculture industry. Due to the lack of licens…
View article: Predictive Value of Lipoprotein(a) for Stroke Recurrence Risk in Embolic Stroke Patients with Different Pathogenesis
Predictive Value of Lipoprotein(a) for Stroke Recurrence Risk in Embolic Stroke Patients with Different Pathogenesis Open
Background Acute embolic stroke has a high risk of recurrence, including artery-to-artery embolic, cardioembolism, and embolic stroke of undetermined source. Whether lipoprotein(a) contributes to stroke recurrence risk in embolic stroke pa…
View article: Microbiology and Clinical Outcome of Bloodstream Infections in Patients After Hematopoietic Stem Cell Transplantation
Microbiology and Clinical Outcome of Bloodstream Infections in Patients After Hematopoietic Stem Cell Transplantation Open
Our study reveals the microbiological characteristics and 30-day all-cause mortality in patients with bloodstream infections after HSCT. Our data provides strong support for empirical antimicrobial therapy and infection prevention strategi…
View article: Uhthoff’s phenomenon as the initial symptom in neuromyelitis optica spectrum disorders: a case report
Uhthoff’s phenomenon as the initial symptom in neuromyelitis optica spectrum disorders: a case report Open
View article: U-shaped association between low-density lipoprotein cholesterol levels and risk of all-cause mortality mediated by post-stroke infection in acute ischemic stroke
U-shaped association between low-density lipoprotein cholesterol levels and risk of all-cause mortality mediated by post-stroke infection in acute ischemic stroke Open
During the acute stage of ischemic stroke, it remains unclear how to interpret the low low-density lipoprotein cholesterol (LDL-C) level. We aimed to evaluate the association between LDL-C levels, post-stroke infection, and all-cause morta…
View article: Ginsenoside Rb1 Interfered with Macrophage Activation by Activating PPARγ to Inhibit Insulin Resistance in Obesity
Ginsenoside Rb1 Interfered with Macrophage Activation by Activating PPARγ to Inhibit Insulin Resistance in Obesity Open
Type 2 diabetes (T2D) is characterized by insulin resistance (IR), often accompanied by inflammation. Macrophage activation acts as an inflammatory response, which is characterized by macrophage recruitment in the initial stage. Ginsenosid…
View article: Elevated Homocysteine Intensify the Effect of Lipoprotein(a) on Stroke Recurrence
Elevated Homocysteine Intensify the Effect of Lipoprotein(a) on Stroke Recurrence Open