Linghuo Jiang
YOU?
Author Swipe
View article: Expression of CMK2 is controlled by the general stress-response transcriptional factor Msn2 through a single STRE site in budding yeast
Expression of CMK2 is controlled by the general stress-response transcriptional factor Msn2 through a single STRE site in budding yeast Open
Mammalian calcium/calmodulin-dependent protein kinase II (CaMKII) is a memory molecule in the brain, and regulates fatty acids and lipid metabolism. As a yeast homolog of CaMKII, Cmk2 is a negative feed-back regulator of calcium signaling …
View article: The calcineurin-responsive transcription factor Crz1 regulates the expression of CMK2 via a sole CDRE site in its promoter in budding yeast
The calcineurin-responsive transcription factor Crz1 regulates the expression of CMK2 via a sole CDRE site in its promoter in budding yeast Open
As a yeast homolog of mammalian calcium/calmodulin-dependent protein kinase II (CaMKII), Cmk2 functions as a negative regulator of calcium signaling in Saccharomyces cerevisiae. We show here that the transcription expression of CMK2 is con…
View article: Amino acid metabolism and MAP kinase signaling pathway play opposite roles in the regulation of ethanol production during fermentation of sugarcane molasses in budding yeast
Amino acid metabolism and MAP kinase signaling pathway play opposite roles in the regulation of ethanol production during fermentation of sugarcane molasses in budding yeast Open
Sugarcane molasses is one of the main raw materials for bioethanol production, and Saccharomyces cerevisiae is the major biofuel-producing organism. In this study, a batch fermentation model has been used to examine ethanol titers of delet…
View article: Transcriptional expression of <i>PHR2</i> is positively controlled by the calcium signaling transcription factor Crz1 through its binding motif in the promoter
Transcriptional expression of <i>PHR2</i> is positively controlled by the calcium signaling transcription factor Crz1 through its binding motif in the promoter Open
GH72 family of β-(1,3)-glucanosyltransferases is required for cell wall biogenesis, morphogenesis, and virulence of fungi. Candida albicans PHR2 is an acidic pH-induced gene that encodes a GH72 enzyme involved in cross-linking of β−1,3- an…
View article: Additional file 1 of A glycosylated Phr1 protein is induced by calcium stress and its expression is positively controlled by the calcium/calcineurin signaling transcription factor Crz1 in Candida albicans
Additional file 1 of A glycosylated Phr1 protein is induced by calcium stress and its expression is positively controlled by the calcium/calcineurin signaling transcription factor Crz1 in Candida albicans Open
Additional file 1: Figure S1. Transcript levels of PHR1genein the wild type SN148 and its isogenic mutant crz1/crz1cells growing in log phase in the presence or absence of0.2M CaCl2for 2 hours. Figure S2. Knockoutstrategy of two alleles of…
View article: Corrigendum to &lt;‘CaTip41 regulates protein phosphatase 2A activity, CaRad53 deactivation and the recovery of DNA damage-induced filamentation to yeast form in <i>Candida albicans</i>’&gt;
Corrigendum to <‘CaTip41 regulates protein phosphatase 2A activity, CaRad53 deactivation and the recovery of DNA damage-induced filamentation to yeast form in <i>Candida albicans</i>’> Open
The authors r egr et that the ima ge showing the interaction between CaTip41and CaTap42 in Figure 2 was inadv ertentl y switched for a different image .T herefore , the mistaken image was replaced with the correct image to show the interac…
View article: Fabrication of Silver Nanoparticles Against Fungal Pathogens
Fabrication of Silver Nanoparticles Against Fungal Pathogens Open
The use of silver nanoparticles (AgNPs) against various pathogens is now being well recognized in the agriculture and health sector. Nanoparticles have been shown to exhibit various novel properties and these properties, on other hand, rel…
View article: RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans
RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans Open
Background The calcium/calcineurin signaling pathway is mediated by the transcription factors NFAT (nuclear factor of activated T cells) in mammals and Crz1 (calcineurin-responsive zinc finger 1) in yeasts and other lower eukaryotes. A pre…
View article: MOESM3 of RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans
MOESM3 of RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans Open
Additional file 3. Promoter analysis of 219 genes whose expression is positively regulated by CaCrz1#
View article: MOESM4 of RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans
MOESM4 of RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans Open
Additional file 4. Comparison of calcium-specific and Crz1-dependent genes in Saccharomyces cerevisiae and Candida albicans.
View article: The lipid flippase subunit Cdc50 is required for antifungal drug resistance, endocytosis, hyphal development and virulence in<i>Candida albicans</i>
The lipid flippase subunit Cdc50 is required for antifungal drug resistance, endocytosis, hyphal development and virulence in<i>Candida albicans</i> Open
Cdc50 is the non-catalytic subunit of the flippase that establishes phospholipid asymmetry in membranes and functions in vesicle-mediated trafficking in Saccharomyces cerevisiae. Here, we have identified the homologous gene CaCDC50 that en…
View article: CaGdt1 plays a compensatory role for the calcium pump CaPmr1 in the regulation of calcium signaling and cell wall integrity signaling in Candida albicans
CaGdt1 plays a compensatory role for the calcium pump CaPmr1 in the regulation of calcium signaling and cell wall integrity signaling in Candida albicans Open
CaPmr1 is the major player in the regulation of calcium homeostasis and cell wall stress, while CaGdt1 plays a compensatory role for CaPmr1 in the Golgi compartment in C. albicans.
View article: The putative transcription factor CaMaf1 controls the sensitivity to lithium and rapamycin and represses RNA polymerase III transcription in Candida albicans
The putative transcription factor CaMaf1 controls the sensitivity to lithium and rapamycin and represses RNA polymerase III transcription in Candida albicans Open
Maf1 is a repressor of RNA polymerase (Pol) III transcription for tRNA. Nutrient deprivation and environmental stress repress Pol III transcription through Maf1 in Saccharomyces cerevisiae. The sole Candida albicans homolog CaMaf1 is a pro…
View article: The endosomal sorting complex required for transport (ESCRT) is required for the sensitivity of yeast cells to nickel ions in<i>Saccharomyces cerevisiae</i>
The endosomal sorting complex required for transport (ESCRT) is required for the sensitivity of yeast cells to nickel ions in<i>Saccharomyces cerevisiae</i> Open
Nickel is one of the toxic environment metal pollutants and is linked to various human diseases. In this study, through a functional genomics approach we have identified 16 nickel-sensitive and 22 nickel-tolerant diploid deletion mutants o…
View article: The transcription factor Ace2 and its paralog Swi5 regulate ethanol production during static fermentation through their targets Cts1 and Rps4a in<i>Saccharomyces cerevisiae</i>
The transcription factor Ace2 and its paralog Swi5 regulate ethanol production during static fermentation through their targets Cts1 and Rps4a in<i>Saccharomyces cerevisiae</i> Open
Saccharomyces cerevisiae is the most widely used fermentation organism for ethanol production. However, the gene expression regulatory networks behind the ethanol fermentation are still not fully understood. Using a static fermentation mod…
View article: CaTip41 regulates protein phosphatase 2A activity, CaRad53 deactivation and the recovery of DNA damage-induced filamentation to yeast form in<i>Candida albicans</i>
CaTip41 regulates protein phosphatase 2A activity, CaRad53 deactivation and the recovery of DNA damage-induced filamentation to yeast form in<i>Candida albicans</i> Open
Phosphorylation and dephosphorylation of the checkpoint kinase CaRad53 is crucial for fungal cells in response to genotoxic stresses. The protein phosphatase 2A (PP2A) CaPph3/CaPsy2 phosphatase complex is involved in CaRad53 dephosphorylat…
View article: Vcx1-D1 (M383I), the Vcx1 mutant with a calcineurin-independent vacuolar Ca<sup>2+</sup>/H<sup>+</sup> exchanger activity, confers calcineurin-independent Mn<sup>2+</sup> tolerance in <i>Saccharomyces cerevisiae</i>
Vcx1-D1 (M383I), the Vcx1 mutant with a calcineurin-independent vacuolar Ca<sup>2+</sup>/H<sup>+</sup> exchanger activity, confers calcineurin-independent Mn<sup>2+</sup> tolerance in <i>Saccharomyces cerevisiae</i> Open
The Vcx1-M1 mutant is known to confer calcineurin-dependent Mn 2+ tolerance in budding yeast. Here, we demonstrate that another Vcx1 mutant, Vcx1-D1 with calcineurin-independent vacuolar Ca 2+ /H + exchanger activity, confers calcineurin-i…