Junyu Pei
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View article: Associations and predictive value of weight-adjusted waist index for cardiovascular outcomes in type 2 diabetes: evidence from the ACCORD study
Associations and predictive value of weight-adjusted waist index for cardiovascular outcomes in type 2 diabetes: evidence from the ACCORD study Open
WWI is closely associated with future cardiovascular outcomes and TM in patients with T2DM.WWI serves as an autonomous predictor of both future cardiovascular events and TM among patients with T2DM, outperforming traditional obesity indice…
View article: BRI shows stronger association than BMI for MACE in patients with T2DM: insights from the ACCORD study
BRI shows stronger association than BMI for MACE in patients with T2DM: insights from the ACCORD study Open
Objective This study investigated the associations of the body roundness index (BRI) with major adverse cardiovascular events (MACEs, including non-fatal myocardial infarction, non-fatal stroke, and cardiovascular death) and total mortalit…
View article: Association between estimated glucose disposal rate and major adverse cardiovascular events in patients with type 2 diabetes.
Association between estimated glucose disposal rate and major adverse cardiovascular events in patients with type 2 diabetes. Open
In type 2 diabetes patients with high cardiovascular risk, lower eGDR was associated with higher risk of MACEs and all-cause mortality, with HbA1c variability playing an important mediating role in this relationship.
View article: The effect of <scp>HbA1c</scp> variability on the efficacy of intensive blood pressure control in patients with type 2 diabetes
The effect of <span>HbA1c</span> variability on the efficacy of intensive blood pressure control in patients with type 2 diabetes Open
Aims The efficacy of intensive blood pressure (BP) control remains controversial, and the variability of HbA1c was a risk factor for macrovascular events in patients with type 2 diabetes. We investigated whether the HbA1c variability modif…
View article: Association of non‐high‐density lipoprotein cholesterol/high‐density lipoprotein cholesterol ratio with cardiovascular outcomes in patients with type 2 diabetes mellitus: Evidence from the <scp>ACCORD</scp> cohort
Association of non‐high‐density lipoprotein cholesterol/high‐density lipoprotein cholesterol ratio with cardiovascular outcomes in patients with type 2 diabetes mellitus: Evidence from the <span>ACCORD</span> cohort Open
Aim To explore the association between the non‐high‐density lipoprotein cholesterol (HDL‐C)/HDL‐C ratio (NHHR) and the risk of major adverse cardiovascular events (MACEs) and overall mortality in patients with type 2 diabetes mellitus (T2D…
View article: HbA1c variability and macrovascular benefits of intensive blood pressure control in patients with type 2 diabetes
HbA1c variability and macrovascular benefits of intensive blood pressure control in patients with type 2 diabetes Open
Background Hypertension is the most common and manageable cardiovascular risk factor in patients with type 2 diabetes. However, the optimal target for blood pressure (BP) control in patients with type 2 diabetes remains a subject of debate…
View article: Dissecting the role of cannabinoids in vascular health and disease
Dissecting the role of cannabinoids in vascular health and disease Open
Cannabis, often recognized as the most widely used illegal psychoactive substance globally, has seen a shift in its legal status in several countries and regions for both recreational and medicinal uses. This change has brought to light ne…
View article: Elevated Glucose on Admission Was an Independent Risk Factor for 30-Day Major Adverse Cardiovascular Events in Patients with STEMI but Not NSTEMI
Elevated Glucose on Admission Was an Independent Risk Factor for 30-Day Major Adverse Cardiovascular Events in Patients with STEMI but Not NSTEMI Open
Background: The purpose of this study was to evaluate the impact of glucose levels on admission, on the risk of 30-day major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI), and to assess the differ…
View article: Association Between the Frailty and Cognitive Impairment Among Patients With Hypertension—A Post Hoc Analysis of the SPRINT Trial
Association Between the Frailty and Cognitive Impairment Among Patients With Hypertension—A Post Hoc Analysis of the SPRINT Trial Open
Background Frailty and cognitive impairment are common in the elderly, with various shared risk factors like hypertension. Frailty is a marker for future cognitive function. Moreover, whether intensive blood pressure interacted with frailt…
View article: Elevated Glucose on Admission Was an Independent Risk Factor For 30-Day Major Adverse Cardiovascular Events in Patients with STEMI But Not NSTEMI
Elevated Glucose on Admission Was an Independent Risk Factor For 30-Day Major Adverse Cardiovascular Events in Patients with STEMI But Not NSTEMI Open
Objectives The purpose of this study was to evaluate the impact of glucose levels on admission on the risk of 30-day major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI), and to assess the differen…
View article: Elevated admission blood glucose is an independent risk factor for 30-Day major adverse cardiovascular events in STEMI patients, but not in NSTEMI patients
Elevated admission blood glucose is an independent risk factor for 30-Day major adverse cardiovascular events in STEMI patients, but not in NSTEMI patients Open
Background Elevated admission blood glucose was associated with adverse outcomes in patients with acute myocardial infarction (AMI). However, no further studies investigated the association between admission blood glucose and 30-day major …
View article: Gut bacterial metabolite Urolithin A inhibits myocardial fibrosis through activation of Nrf2 pathway in vitro and in vivo
Gut bacterial metabolite Urolithin A inhibits myocardial fibrosis through activation of Nrf2 pathway in vitro and in vivo Open
Background Myocardial fibrosis after myocardial infarction (MI) is one of the leading causes of cardiovascular diseases. Cardiac fibroblasts (CFs) are activated and promoted by MI to undergo myofibroblast transformation (CMT). Urolithin A …
View article: Traditional Cardiovascular Risk Factors and Coronary Collateral Circulation: A Meta-Analysis
Traditional Cardiovascular Risk Factors and Coronary Collateral Circulation: A Meta-Analysis Open
Objective: Patients with well-developed coronary collateral circulation (CC) usually have low mortality, improved cardiac function, and reduced infarct size. Currently, there is conflicting evidence on the association between traditional c…
View article: The association of interferon‐alpha with development of collateral circulation after artery occlusion
The association of interferon‐alpha with development of collateral circulation after artery occlusion Open
Background Previous studies have demonstrated that interferon (IFN) signaling is enhanced in patients with poor collateral circulation (CC). However, the role and mechanisms of IFN‐alpha in the development of CC remain unknown. Methods We …
View article: Hb Levels and Sex Differences in Relation to Short-Term Outcomes in Patients With Acute Myocardial Infarction
Hb Levels and Sex Differences in Relation to Short-Term Outcomes in Patients With Acute Myocardial Infarction Open
Background: Women had worse outcomes after acute myocardial infarction (AMI), and physiologically, women had lower hemoglobin values. We examined whether there were sex-related differences in the relationship between hemoglobin levels and …
View article: High‐density lipoprotein cholesterol levels are associated with major adverse cardiovascular events in male but not female patients with hypertension
High‐density lipoprotein cholesterol levels are associated with major adverse cardiovascular events in male but not female patients with hypertension Open
Background The relationship between high‐density lipoprotein cholesterol (HDL‐C) levels and major adverse cardiovascular events (MACEs) in hypertensive patients of different sexes is unclear. Hypothesis Sex differences in the relationship …
View article: Short‐term and long‐term outcomes of revascularization interventions for patients with severely reduced left ventricular ejection fraction: a meta‐analysis
Short‐term and long‐term outcomes of revascularization interventions for patients with severely reduced left ventricular ejection fraction: a meta‐analysis Open
Aims This meta‐analysis aimed to determine whether coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) should be preferred in patients with severely reduced left ventricular (LV) ejection fraction. Methods an…
View article: Post-Procedural Anticoagulation After Primary Percutaneous Coronary Intervention for Anterior Acute Myocardial Infarction With Severe Left Ventricular Dysfunction
Post-Procedural Anticoagulation After Primary Percutaneous Coronary Intervention for Anterior Acute Myocardial Infarction With Severe Left Ventricular Dysfunction Open
Short-term PPAC using enoxaparin after primary PCI may be an effective and safe way to prevent LVT in patients with anterior AMI and LV dysfunction.
View article: Association between admission systolic blood pressure and major adverse cardiovascular events in patients with acute myocardial infarction
Association between admission systolic blood pressure and major adverse cardiovascular events in patients with acute myocardial infarction Open
URL: http://www.clinicaltrials.gov. Unique identifier: NCT02256657.
View article: Pulmonary artery sarcoma feigning pulmonary thromboembolism
Pulmonary artery sarcoma feigning pulmonary thromboembolism Open
A 53-year-old man presented with exertional dyspnea and chest pain over 6 months, and suddenly developed hemoptysis 10 days ago.Contrast-enhanced computed tomography (CT) showed three filling defects in the main pulmonary artery, right pul…
View article: The Brain-Heart Connection in Takotsubo Syndrome: The Central Nervous System, Sympathetic Nervous System, and Catecholamine Overload
The Brain-Heart Connection in Takotsubo Syndrome: The Central Nervous System, Sympathetic Nervous System, and Catecholamine Overload Open
Takotsubo syndrome (TTS), also known as stress cardiomyopathy, is a type of acute heart failure syndrome triggered by intense psychological or physiological stress. TTS typically manifests as acute chest pain, dyspnea or syncope that mimic…
View article: Prognostic value of admission electrocardiographic findings in non‐ST‐segment elevation myocardial infarction
Prognostic value of admission electrocardiographic findings in non‐ST‐segment elevation myocardial infarction Open
Background Admission electrocardiographic (ECG) findings of non‐ST‐segment elevation myocardial infarction (NSTEMI) include transient ST‐segment elevation (TSTE), ST‐segment depression (STD), T‐wave inversion (TWI), and no ischemic changes…
View article: Association of predicted lean body mass and fat mass with cardiovascular events in patients with type 2 diabetes mellitus
Association of predicted lean body mass and fat mass with cardiovascular events in patients with type 2 diabetes mellitus Open
In patients with T2DM, we found that predicted fat mass had a strong positive association with a higher risk of a major adverse cardiovascular event. Increasing lean body mass did not have a protective role. Trial registration: ClinicalTri…