Jinlin Du
YOU?
Author Swipe
View article: Efficacy and liver function preservation with donafenib combined with transarterial chemoembolization in unresectable hepatocellular carcinoma: An ALBI grade analysis
Efficacy and liver function preservation with donafenib combined with transarterial chemoembolization in unresectable hepatocellular carcinoma: An ALBI grade analysis Open
Purpose This study evaluated the hepatoprotective effects and safety profile of donafenib combined with transarterial chemoembolization (TACE) in unresectable hepatocellular carcinoma (HCC) through analysis of albumin-bilirubin (ALBI) scor…
View article: Correction: Triple therapy revolutionizes treatment paradigms for previously untreatable HCC complicated by high-flow hepatic arteriovenous fistulas
Correction: Triple therapy revolutionizes treatment paradigms for previously untreatable HCC complicated by high-flow hepatic arteriovenous fistulas Open
[This corrects the article DOI: 10.3389/fimmu.2025.1643290.].
View article: Triple therapy revolutionizes treatment paradigms for previously untreatable HCC complicated by high-flow hepatic arteriovenous fistulas
Triple therapy revolutionizes treatment paradigms for previously untreatable HCC complicated by high-flow hepatic arteriovenous fistulas Open
Purpose To evaluate the short-term efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) combined with immune checkpoint inhibitors (ICIs) and tyrosine kinase inhibitors (TKIs) in patients with hepatocellular carcinoma (HCC)…
View article: Risk Factors and Predictive Analysis of Acute Severe Abdominal Pain After Hepatic Artery Infusion Chemotherapy in Patients with Hepatocellular Carcinoma
Risk Factors and Predictive Analysis of Acute Severe Abdominal Pain After Hepatic Artery Infusion Chemotherapy in Patients with Hepatocellular Carcinoma Open
The model developed in this study effectively predicted the risk of acute moderate to severe abdominal pain following HAIC and may provide a basis for more precise prevention and intervention strategies in clinical practice.
View article: Integrative metabolome and transcriptome analyses provide insights into PHGDH in colon cancer organoids
Integrative metabolome and transcriptome analyses provide insights into PHGDH in colon cancer organoids Open
As a rate-limiting enzyme in the endogenous serine de novo synthesis pathway, 3-Phosphoglycerate dehydrogenase (PHGDH) has been widely concerned about its role in a variety of tumors including colon cancer and the development of inhibitors…
View article: Node-sparing modified short-course Radiotherapy Combined with CAPOX and Tislelizumab for locally Advanced MSS of Middle and low rectal Cancer (mRCAT): an open-label, single-arm, prospective, multicentre clinical trial
Node-sparing modified short-course Radiotherapy Combined with CAPOX and Tislelizumab for locally Advanced MSS of Middle and low rectal Cancer (mRCAT): an open-label, single-arm, prospective, multicentre clinical trial Open
NCT05972655. Date of registration: 31 July 2023.
View article: Identification and prognostic analysis of candidate biomarkers for lung metastasis in colorectal cancer
Identification and prognostic analysis of candidate biomarkers for lung metastasis in colorectal cancer Open
Colorectal cancer (CRC) is one of the most prevalent types of malignant tumors. It’s vital to explore new biomarkers and potential therapeutic targets in CRC lung metastasis through adopting integrated bioinformatics tools. Multiple cohort…
View article: Node-Sparing Modified Short-Course Radiotherapy Combined with CAPOX and Tislelizumab for Locally Advanced MSS of Middle and Low Rectal Cancer (mRCAT): An open-label, single-arm, prospective, multicentre clinical trial
Node-Sparing Modified Short-Course Radiotherapy Combined with CAPOX and Tislelizumab for Locally Advanced MSS of Middle and Low Rectal Cancer (mRCAT): An open-label, single-arm, prospective, multicentre clinical trial Open
Background Neoadjuvant chemoradiotherapy followed by total mesorectal excision is a standard treatment for locally advanced rectal cancer. Mismatch repair-deficient locally advanced rectal cancer was highly sensitive to PD-1 blockade. Howe…
View article: Influence of hypoxia on retinal progenitor and ganglion cells in human induced pluripotent stem cell-derived retinal organoids
Influence of hypoxia on retinal progenitor and ganglion cells in human induced pluripotent stem cell-derived retinal organoids Open
AIM: To observe the effect of low oxygen concentration on the neural retina in human induced pluripotent stem cell (hiPSC)-derived retinal organoids (ROs). METHODS: The hiPSC and a three-dimensional culture method were used for the experim…
View article: The effect of radiotherapy and surgery on stage IIIA/B NSCLC patients treated with chemotherapy
The effect of radiotherapy and surgery on stage IIIA/B NSCLC patients treated with chemotherapy Open
Background: The combination of radiotherapy and surgery is used to treat locally advanced non-small cell lung cancer (NSCLC). The aim of this study was to analyze IIIA/B NSCLC patients treated with chemotherapy from the Surveillance, Epide…
View article: Data from Hepatitis B Virus Infection and Risk of Nasopharyngeal Carcinoma in Southern China
Data from Hepatitis B Virus Infection and Risk of Nasopharyngeal Carcinoma in Southern China Open
Background: Whether or not hepatitis B virus (HBV) infection plays a role in the development of nasopharyngeal carcinoma (NPC) is largely unknown. Our study aimed to assess the association between HBV infection and the risk of NPC in South…
View article: Data from Hepatitis B Virus Infection and Risk of Nasopharyngeal Carcinoma in Southern China
Data from Hepatitis B Virus Infection and Risk of Nasopharyngeal Carcinoma in Southern China Open
Background: Whether or not hepatitis B virus (HBV) infection plays a role in the development of nasopharyngeal carcinoma (NPC) is largely unknown. Our study aimed to assess the association between HBV infection and the risk of NPC in South…
View article: The impact of age on outcomes of breast cancer in different hormone receptor and HER2 groups
The impact of age on outcomes of breast cancer in different hormone receptor and HER2 groups Open
Objective The aim of the current study was to explore the association between age and outcomes in breast cancer. Methods Patients during 2010–2015 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. Overal…
View article: Phase II study of anlotinib in combination with oxaliplatin and capecitabine for patients with RAS/BRAF wild-type metastatic colorectal adenocarcinoma as the first-line therapy
Phase II study of anlotinib in combination with oxaliplatin and capecitabine for patients with RAS/BRAF wild-type metastatic colorectal adenocarcinoma as the first-line therapy Open
Background Anlotinib, an oral small molecule tyrosine kinase inhibitor targeting VEGFR 1/2/3, FGFR 1-4, PDGFR a/β, and c-kit, had demonstrated prolonged progression-free survival (PFS) in refractory metastatic colorectal cancer (mCRC). Thi…
View article: [Retracted] Exosomal miRNA Expression Profiling and the Roles of Exosomal miR‐4741, miR‐32, miR‐3149, and miR‐6727 on Gastric Cancer Progression
[Retracted] Exosomal miRNA Expression Profiling and the Roles of Exosomal miR‐4741, miR‐32, miR‐3149, and miR‐6727 on Gastric Cancer Progression Open
Objective . Accumulated evidence highlights the biological implications of exosomes in gastric cancer. Herein, we conducted the exosomal miRNA expression profiling and identified potential diagnostic markers for gastric cancer. Methods . P…
View article: Adiponectin Suppresses Tumor Growth of Nasopharyngeal Carcinoma Through Activating AMPK Signaling Pathway
Adiponectin Suppresses Tumor Growth of Nasopharyngeal Carcinoma Through Activating AMPK Signaling Pathway Open
BackgroundAdiponectin is an adipocyte-secreted cytokine that enhances insulin sensitivity and attenuates inflammation. Although circulating adiponectin level is often inversely associated with several malignancies, its role in the developm…
View article: Factors Influencing Quality of Life in Patients with Nasopharyngeal Cancer Based on QLICP-NA (Version 2.0)
Factors Influencing Quality of Life in Patients with Nasopharyngeal Cancer Based on QLICP-NA (Version 2.0) Open
Objective To determine the quality of life (QoL) of patients with nasopharyngeal carcinoma (NPC) and the clinical factors that influence QoL. Methods Multiple linear regression, simple and canonical correlation analyses were used to analyz…
View article: Adverse Histological Features Alone Was Not Sufficient for Decision of Adjuvant Chemotherapy in T3N0M0 colonic cancer: A Propensity Score Matching Study Based on Population Analysis
Adverse Histological Features Alone Was Not Sufficient for Decision of Adjuvant Chemotherapy in T3N0M0 colonic cancer: A Propensity Score Matching Study Based on Population Analysis Open
Purpose: Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Approximately 25% of patients with AJCC stage II suffered recurrence after radical surgery, but the role of adjuvant chemotherapy in Stage II…
View article: Estrogen Receptor-negative/progesterone Receptor-positive and Her-2 Negative Breast Cancer Might No Longer Be Classified as Hormone Receptor Positive Breast Cancer
Estrogen Receptor-negative/progesterone Receptor-positive and Her-2 Negative Breast Cancer Might No Longer Be Classified as Hormone Receptor Positive Breast Cancer Open
Background: The estrogen receptor (ER)-negative/progesterone receptor (PR)-positive (sPR positive) phenotype is an infrequent and independent biological entity. However, the prognosis of patients with sPR positive and her-2 negative phenot…
View article: What factors are associated with the poor prognosis of anal adenocarcinoma compared with low-lying rectal adenocarcinoma based on a population analysis: A propensity score matching study
What factors are associated with the poor prognosis of anal adenocarcinoma compared with low-lying rectal adenocarcinoma based on a population analysis: A propensity score matching study Open
AA confers a worse prognosis than RA does. The T staging criteria of anal carcinoma, dominated by tumor size, seem to be invalid for AA, while the number of positive lymph nodes is a prognostic factor.
View article: <p>Association between potentially functional polymorphisms of chemokine family members and the survival of esophageal cancer patients in a Chinese population</p>
Association between potentially functional polymorphisms of chemokine family members and the survival of esophageal cancer patients in a Chinese population Open
Background: The chemokine family plays an important role in the growth, invasion, and metastasis of tumors. However, most studies have only focused on a few genes or a few gene loci, and thus could not reveal the associations between funct…
View article: Peer Review #3 of "Impact of old age on resectable colorectal cancer outcomes (v0.1)"
Peer Review #3 of "Impact of old age on resectable colorectal cancer outcomes (v0.1)" Open
Objective: This study was performed to identify a reasonable cutoff age for defining older patients with colorectal cancer (CRC) and to examine whether old age was related with increased colorectal cancerspecific death (CSD) and poor color…