Jiangwei Yan
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View article: Proteomic signature of aging in bloodstain samples: a preliminary study
Proteomic signature of aging in bloodstain samples: a preliminary study Open
Background Age estimation from biological samples remains a critical challenge in forensic investigations, particularly when analyzing trace or degraded biological stains recovered from crime scenes. While DNA methylation has gained attent…
View article: Integrated genetic and geographic ancestry prediction via large-scale genomic data and machine learning
Integrated genetic and geographic ancestry prediction via large-scale genomic data and machine learning Open
View article: Largest-Scale Genomic Resource Reconstructing the Genetic Origin, Population Structure, and Biological Adaptations of the Hui People
Largest-Scale Genomic Resource Reconstructing the Genetic Origin, Population Structure, and Biological Adaptations of the Hui People Open
Historical and archaeological records indicate that the Maritime and Land Silk Roads played a pivotal role in facilitating Trans-Eurasian migrations and cultural exchanges. However, the extent to which population movements or the spread of…
View article: Viral community succession during cadaver decomposition and its potential for estimating postmortem intervals
Viral community succession during cadaver decomposition and its potential for estimating postmortem intervals Open
Microbial communities play a vital role in cadaver decomposition and serve as reliable tools for postmortem interval (PMI) estimation. However, current research focuses primarily on bacterial/fungal communities, though viruses—as Earth’s m…
View article: YanHuang Paternal Genomic Resource Suggested A Weakly-Differentiated Multi-Source Admixture Model for the Formation of Han’s Founding Ancestral Lineages
YanHuang Paternal Genomic Resource Suggested A Weakly-Differentiated Multi-Source Admixture Model for the Formation of Han’s Founding Ancestral Lineages Open
The revolution in large-scale human genomics and advancements in statistical methods have profoundly refined our understanding of genetic diversity and structure within human populations. Y-chromosome variations, with their distinct evolut…
View article: The mechanisms and application prospects of exosomes in acute myocardial infarction
The mechanisms and application prospects of exosomes in acute myocardial infarction Open
Acute myocardial infarction (AMI) is a significant cause of death in cardiovascular diseases and an important topic in forensic pathology. It triggers various cellular pathological changes, leading to ventricular remodeling, changes in car…
View article: Identification of enterotype for patients with Alzheimer’s disease
Identification of enterotype for patients with Alzheimer’s disease Open
Analysis of three 16 S rRNA gut microbiome datasets identified three distinct enterotypes: Escherichia_Shigella (ET-E), Faecalibacterium (ET-F), and Bacteroides (ET-B). The ET-E is mainly characterized by the absence of Akkermansia in AD g…
View article: Publisher Correction: Transcriptomic profiling and machine learning reveal novel RNA signatures for enhanced molecular characterization of Hashimoto’s thyroiditis
Publisher Correction: Transcriptomic profiling and machine learning reveal novel RNA signatures for enhanced molecular characterization of Hashimoto’s thyroiditis Open
View article: YHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database
YHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database Open
This work successfully integrated Y-chromosome-related basic genomic science with forensic and anthropological translational applications, emphasizing the necessity of comprehensively characterizing Y-chromosome genomic diversity from geno…
View article: AI-driven Streaming Customer Churn Prediction and Management Research
AI-driven Streaming Customer Churn Prediction and Management Research Open
Against the backdrop of increasingly fierce competition in the streaming media field, how to prevent customer churn has become a severe test faced by major operating platforms. The use of artificial intelligence technology, especially in-d…
View article: Transcriptomic profiling and machine learning reveal novel RNA signatures for enhanced molecular characterization of Hashimoto’s thyroiditis
Transcriptomic profiling and machine learning reveal novel RNA signatures for enhanced molecular characterization of Hashimoto’s thyroiditis Open
View article: Integrated Genetic and Geographic Ancestry Prediction Using Large-Scale Genomic Data and Machine Learning
Integrated Genetic and Geographic Ancestry Prediction Using Large-Scale Genomic Data and Machine Learning Open
View article: Non-Destructive Identification of Forensically Relevant Body Fluid Stains Using a Portable Electronic Nose: A Pilot Study
Non-Destructive Identification of Forensically Relevant Body Fluid Stains Using a Portable Electronic Nose: A Pilot Study Open
View article: Rapid sequencing and identification for 18-STRs long amplicon panel using portable devices and nanopore sequencer
Rapid sequencing and identification for 18-STRs long amplicon panel using portable devices and nanopore sequencer Open
STRs are the most commonly used forensic genetic markers for human identification. Nanopore sequencing has shown the advantages of high portability and large data throughput. Previous studies indicate it has great potential for profiling S…
View article: Integrative analysis of gut microbiome and host transcriptome reveal novel molecular signatures in Hashimoto's thyroiditis
Integrative analysis of gut microbiome and host transcriptome reveal novel molecular signatures in Hashimoto's thyroiditis Open
Our study reveals novel molecular signatures linking gut microbiome and host transcriptome in HT, providing new insights into the disease pathogenesis. These findings not only enhance our understanding of the gut-thyroid axis but also sugg…
View article: Forensic STR and SNP Genotyping of Formalin‐Fixed Skeleton Samples With Illumina's ForenSeq System
Forensic STR and SNP Genotyping of Formalin‐Fixed Skeleton Samples With Illumina's ForenSeq System Open
Formalin fixatives are widely used in forensics to preserve tissues. However, extracting high‐quality genomic DNA from formalin‐fixed samples is challenging. Traditional short tandem repeat (STR) analysis using capillary electrophoresis (C…
View article: NASTRA: accurate analysis of short tandem repeat markers by nanopore sequencing with repeat-structure-aware algorithm
NASTRA: accurate analysis of short tandem repeat markers by nanopore sequencing with repeat-structure-aware algorithm Open
Short-tandem repeats (STRs) are the type of genetic markers extensively utilized in biomedical and forensic applications. Due to sequencing noise in nanopore sequencing, accurate analysis methods are lacking. We developed NASTRA, an innova…
View article: Multiple Human Population Movements and Cultural Dispersal Events Shaped the Landscape of Chinese Paternal Heritage
Multiple Human Population Movements and Cultural Dispersal Events Shaped the Landscape of Chinese Paternal Heritage Open
Large-scale genomic projects and ancient DNA innovations have ushered in a new paradigm for exploring human evolutionary history. However, the genetic legacy of spatiotemporally diverse ancient Eurasians within Chinese paternal lineages re…
View article: Editorial: Artificial intelligence in forensic microbiology, volume II
Editorial: Artificial intelligence in forensic microbiology, volume II Open
Keywords: artificial intelligence, pattern recognition, machine learning, forensic microbiology, medical information
View article: Case reports on uniparental disomy of chromosomes 6 and 3 in paternity testing
Case reports on uniparental disomy of chromosomes 6 and 3 in paternity testing Open
In paternity testing, when there are Mendelian errors in the alleles between the child and the parents, a slippage mutation, or silent allele may not fully explain the phenomenon. Sometimes, it is attributed to chromosomal abnormalities, s…
View article: Malaria resistance-related biological adaptation and complex evolutionary footprints inferred from one integrative Tai-Kadai-related genomic resource
Malaria resistance-related biological adaptation and complex evolutionary footprints inferred from one integrative Tai-Kadai-related genomic resource Open
Pathogen‒host adaptative interactions and complex population demographical processes, including admixture, drift, and Darwen selection, have considerably shaped the Neolithic-to-Modern Western Eurasian population structure and genetic susc…
View article: Effectiveness Evaluation of the Novel miRNA-based Forensic Age Estimation Strategy for Blood Samples in Forensic Science
Effectiveness Evaluation of the Novel miRNA-based Forensic Age Estimation Strategy for Blood Samples in Forensic Science Open
Age estimation has always been an important issue in forensic science, which is of great significance in narrowing the scope of suspects and sentencing in the judiciary.
View article: Body fluids should be identified before estimating the time since deposition (TsD) in microbiome-based stain analyses for forensics
Body fluids should be identified before estimating the time since deposition (TsD) in microbiome-based stain analyses for forensics Open
Identification and the time since deposition (TsD) estimation of body fluid stains from a crime scene could provide valuable information for solving the cases and are always difficult for forensics. Microbial characteristics were considere…
View article: Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations
Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations Open
View article: Roles of Myokines and Muscle-Derived Extracellular Vesicles in Musculoskeletal Deterioration under Disuse Conditions
Roles of Myokines and Muscle-Derived Extracellular Vesicles in Musculoskeletal Deterioration under Disuse Conditions Open
Prolonged inactivity and disuse conditions, such as those experienced during spaceflight and prolonged bedrest, are frequently accompanied by detrimental effects on the motor system, including skeletal muscle atrophy and bone loss, which g…
View article: Differentiated genomic footprints suggest isolation and long-distance migration of Hmong-Mien populations
Differentiated genomic footprints suggest isolation and long-distance migration of Hmong-Mien populations Open
Background The underrepresentation of Hmong-Mien (HM) people in Asian genomic studies has hindered our comprehensive understanding of the full landscape of their evolutionary history and complex trait architecture. South China is a multi-e…
View article: Development and Validation of a Multiplex Panel with 232 Microhaplotypes for Forensic Kinship Analysis
Development and Validation of a Multiplex Panel with 232 Microhaplotypes for Forensic Kinship Analysis Open
View article: Enhancing Testing Efficacy of High-Density Snp Microarrays to Distinguish Pedigrees Belonging to the Same Kinship Class
Enhancing Testing Efficacy of High-Density Snp Microarrays to Distinguish Pedigrees Belonging to the Same Kinship Class Open
View article: Male-Specific Age Prediction Based on Y-Chromosome DNA Methylation with Blood Using Pyrosequencing
Male-Specific Age Prediction Based on Y-Chromosome DNA Methylation with Blood Using Pyrosequencing Open
View article: Long Amplicon Panel of Short Tandem Repeats Enables Rapid Library Preparation and Nanopore Sequencing with Portable Devices
Long Amplicon Panel of Short Tandem Repeats Enables Rapid Library Preparation and Nanopore Sequencing with Portable Devices Open