Jianhan Ren
YOU?
Author Swipe
View article: CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis
CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis Open
Diabetes exacerbates the development and progression of periodontitis through the aggravation of persistent inflammation and tissue destruction. While the impact of diabetes on peripheral sensory nerves is well‐documented, little is known …
View article: The effects of clinical crown length on the sagittal movement of maxillary central incisor in clear aligner treatment: a finite element exploration
The effects of clinical crown length on the sagittal movement of maxillary central incisor in clear aligner treatment: a finite element exploration Open
View article: The 100 Most-Cited Randomised Controlled Trials in Orthodontics: A Bibliometric Study
The 100 Most-Cited Randomised Controlled Trials in Orthodontics: A Bibliometric Study Open
View article: Aging-related decrease of histone methyltransferase SUV39H1 in adipose-derived stem cells enhanced SASP
Aging-related decrease of histone methyltransferase SUV39H1 in adipose-derived stem cells enhanced SASP Open
Aging-related diseases are closely associated with the state of inflammation, which is known as "inflammaging." Senescent cells are metabolically active, as exemplified by the secretion of inflammatory cytokines, chemokines, and growth fac…
View article: Effects of probiotics on the oral health of patients undergoing orthodontic treatment: a systematic review and meta-analysis
Effects of probiotics on the oral health of patients undergoing orthodontic treatment: a systematic review and meta-analysis Open
Background and objective The effect of probiotics on oral health maintenance in orthodontic patients remains controversial. The aim of the study is to systematically review and assess the effects of probiotics on the oral health and microb…
View article: The role of non-steroidal anti-inflammatory drugs as adjuncts to periodontal treatment and in periodontal regeneration
The role of non-steroidal anti-inflammatory drugs as adjuncts to periodontal treatment and in periodontal regeneration Open
View article: Effects of Two-Phase Treatment with Functional Appliances Followed by Extraction versus One-Phase Treatment with Extraction in Class II Growing Patients: A Case–Control Study
Effects of Two-Phase Treatment with Functional Appliances Followed by Extraction versus One-Phase Treatment with Extraction in Class II Growing Patients: A Case–Control Study Open
Objectives: Fixed appliance treatment with premolar extraction is often required after functional appliance treatment to relieve crowding and improve facial aesthetics in the Asian population. This study compared the treatment efficacy of …
View article: Mechanosensitive Piezo1 and Piezo2 ion channels in craniofacial development and dentistry: Recent advances and prospects
Mechanosensitive Piezo1 and Piezo2 ion channels in craniofacial development and dentistry: Recent advances and prospects Open
Mechanical forces play important roles in many biological processes and there is increasing interest and understanding of these roles. Mechanotransduction is the process by which mechanical stimuli are converted to biochemical signals thro…
View article: Temporal induction of Lhx8 by optogenetic control system for efficient bone regeneration
Temporal induction of Lhx8 by optogenetic control system for efficient bone regeneration Open
Background The spatiotemporal regulation of essential genes is crucial for controlling the growth and differentiation of cells in a precise manner during regeneration. Recently, optogenetics was considered as a potent technology for sophis…
View article: FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex
FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex Open
The homeobox gene, LIM‐homeobox 8 (Lhx8), has previously been identified as an essential transcription factor for dental mesenchymal development. However, how Lhx8 itself is regulated and regulates odontogenesis remains poorly understood. …
View article: Control of mesenchymal stem cell biology by histone modifications
Control of mesenchymal stem cell biology by histone modifications Open
Mesenchymal stem cells (MSCs) are considered the most promising seed cells for regenerative medicine because of their considerable therapeutic properties and accessibility. Fine-tuning of cell biological processes, including differentiatio…
View article: Tooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release
Tooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release Open
Tooth defect and tooth loss are common clinical diseases in stomatology. Compared with the traditional oral restoration treatment, tooth regeneration has unique advantages and is currently the focus of oral biomedical research. It is known…
View article: Optogenetic control of mesenchymal cell fate towards precise bone regeneration
Optogenetic control of mesenchymal cell fate towards precise bone regeneration Open
Rationale: Spatial-temporal control of cell fate in vivo is of great importance for regenerative medicine. Currently, there remain no practical strategies to tune cell-fate spatial-temporally. Optogenetics is a biological tec…