Jianhua Wang
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View article: Unravelling the Role of PIEZO1 in Adipogenesis of Fibrogenic/Adipogenic Progenitors for Muscle Fat Infiltration After Rotator Cuff Tear
Unravelling the Role of PIEZO1 in Adipogenesis of Fibrogenic/Adipogenic Progenitors for Muscle Fat Infiltration After Rotator Cuff Tear Open
Background Muscular fatty infiltration originated from fibrogenic/adipogenic progenitors (FAPs) is a common issue following rotator cuff tear (RCT) that impairs shoulder function. RCT disrupted the biomechanical equilibrium of the shoulder…
View article: Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids
Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids Open
Background Cartilage repair remains a considerable challenge in regenerative medicine. Despite extensive research on biomaterials for cartilage repair in recent years, issues such as prolonged repair cycles and suboptimal outcomes persist.…
View article: Research on a Detailed Drilling Condition Identification Method Based on the KOA-RF Model
Research on a Detailed Drilling Condition Identification Method Based on the KOA-RF Model Open
The accurate identification of drilling conditions is pivotal for optimizing drilling operations. Detailed condition identification enables refined management of the drilling process, facilitates the detection of non-productive time (NPT),…
View article: Physiological factors affecting purple passion fruit (<i>Passiflora edulis</i> f. <i>edulis</i>) post-storage seed germination
Physiological factors affecting purple passion fruit (<i>Passiflora edulis</i> f. <i>edulis</i>) post-storage seed germination Open
Passiflora edulis f. edulis is recognised as an important tropical and subtropical fruit with cold resistance and desirable flavor. The relationship between seed storage and germination remains unclear. This study evaluated the germination…
View article: Leveraging adenosine triphosphate for cancer theranostics
Leveraging adenosine triphosphate for cancer theranostics Open
Manipulation of the biochemical composition of the tumor microenvironment (TME) is a thriving research area in cancer treatment. Adenosine triphosphate (ATP), a key biochemical component, serves as an energy source for cancer cell prolifer…
View article: Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems
Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems Open
Formononetin (FMN) is a common natural metabolite that can be extracted and isolated from some common botanical drugs. In recent years, FMN has garnered increasing attention due to its beneficial biological activities. In this paper, we sy…
View article: Synchronized capture of 3D shape and color texture based on phase-shifting profilometry
Synchronized capture of 3D shape and color texture based on phase-shifting profilometry Open
View article: Low-Rank EM-Based Imaging for Large-Scale Switched Interferometric Arrays
Low-Rank EM-Based Imaging for Large-Scale Switched Interferometric Arrays Open
International audience
View article: Development of Zalfermin, a Long-Acting Proteolytically Stabilized FGF21 Analog
Development of Zalfermin, a Long-Acting Proteolytically Stabilized FGF21 Analog Open
Here, we describe the development of the FGF21 analog zalfermin (NNC0194-0499, 15), intended for once-weekly sc dosing. Protein engineering was needed to address inherent druggability issues of the natural FGF21 hormone. Thus, deami…
View article: Trajectory Planning for Cooperative Double Unmanned Surface Vehicles Connected with a Floating Rope for Floating Garbage Cleaning
Trajectory Planning for Cooperative Double Unmanned Surface Vehicles Connected with a Floating Rope for Floating Garbage Cleaning Open
Double unmanned surface vehicles (DUSVs) towing a floating rope are more effective at removing large floating garbage on the water’s surface than a single USV. This paper proposes a comprehensive trajectory planner for DUSVs connected with…
View article: Overview of Research Progress on Numerical Simulation Methods for Turbulent Flows Around Underwater Vehicles
Overview of Research Progress on Numerical Simulation Methods for Turbulent Flows Around Underwater Vehicles Open
In this paper, we present an overview of numerical simulation methods for the flow around typical underwater vehicles at high Reynolds numbers, which highlights the dominant flow structures in different regions of interest. This overview c…
View article: Analysis of uneven density of oil-based drilling fluid caused by shale respiration
Analysis of uneven density of oil-based drilling fluid caused by shale respiration Open
Longmaxi shale formation has developed beddings and fractures in southern Sichuan, which is prone to well leakage and wellbore instability. In the drilling process of horizontal section of Ning 209H58-2 well, drilling fluid would loss duri…
View article: Numerical investigations of dam-break flow impacting on an elastic beam using various FSI coupling algorithms
Numerical investigations of dam-break flow impacting on an elastic beam using various FSI coupling algorithms Open
The occurrence of green water and slamming in severe sea conditions can often be simplified as a dam-break problem. The flow characteristics of dam-break are similar with those on a ship’s deck and can result in structural damage. In this …
View article: Evaluation of Geometrical Influence on the Hydrodynamic Characteristics and Power Absorption of Vertical Axisymmetric Wave Energy Converters in Irregular Waves
Evaluation of Geometrical Influence on the Hydrodynamic Characteristics and Power Absorption of Vertical Axisymmetric Wave Energy Converters in Irregular Waves Open
To obtain the mechanical energy of waves from arbitrary directions, the vibration absorbers of wave energy converters (WEC) are usually vertically axisymmetric. In such case, the wave-body interaction hydrodynamics is an essential research…
View article: A Study on the Evacuation of an Extra-Long Highway Tunnel Fire—A Case Study of Chengkai Tunnel
A Study on the Evacuation of an Extra-Long Highway Tunnel Fire—A Case Study of Chengkai Tunnel Open
The smoke from tunnel fires spreads over long distances and is difficult to vent. Smoke accumulation leads to high temperatures, low visibility, and high concentrations of toxic gases, which greatly hinders the evacuation of people inside …
View article: Clay-free biodiesel-based drilling fluid suitable for high temperature
Clay-free biodiesel-based drilling fluid suitable for high temperature Open
This paper introduces the formation of a clay-free biodiesel-based drilling fluid system. The system uses the biodiesel derived from the transesterification between soybean oil and methanol as the continuous phase, which is environmentally…
View article: A Measure of Efl Argumentative Writing Cognitive Load: Scale Development and Validation
A Measure of Efl Argumentative Writing Cognitive Load: Scale Development and Validation Open
View article: 普萘洛尔在精神科治疗的临床应用效果分析
普萘洛尔在精神科治疗的临床应用效果分析 Open
Advanced Materials Science and Technology is a peer-reviewed open access journal published semi-annual online by Omniscient Pte. Ltd. The journal covers the properties, applications and synthesis of new materials related to energy, environ…
View article: A Portfolio Model with Risk Control Policy Based on Deep Reinforcement Learning
A Portfolio Model with Risk Control Policy Based on Deep Reinforcement Learning Open
It was shown that deep reinforcement learning (DRL) has the potential to solve portfolio management problems in recent years. The Twin Delayed Deep Deterministic policy gradient algorithm (TD3) is an actor-critic method, a typical DRL meth…
View article: Implementation of Artificial Compressibility Method for Steady and Unsteady Incompressible Flows Based on Finite Volume Method of Unstructured Grids
Implementation of Artificial Compressibility Method for Steady and Unsteady Incompressible Flows Based on Finite Volume Method of Unstructured Grids Open
The development of a new computational fluid dynamics solver for simulating incompressible flows is described. Unlike traditional pressure-based solvers, the artificial compressibility method simulates both steady and unsteady states. Some…
View article: Application of the 3-dimensional printing images of vertebral body in Anterior Cervical Corpectomy and Fusion (ACCF): A report of 25 case series
Application of the 3-dimensional printing images of vertebral body in Anterior Cervical Corpectomy and Fusion (ACCF): A report of 25 case series Open
View article: Translation Model and Dissemination of Contemporary Chinese Ethnic Literal Works Into the World: An Analysis on English Translation of The Last Quarter of the Moon by American Translator Bruce Humes
Translation Model and Dissemination of Contemporary Chinese Ethnic Literal Works Into the World: An Analysis on English Translation of The Last Quarter of the Moon by American Translator Bruce Humes Open
This study aims to investigate the English translation model and strategy of contemporary Chinese literary masterpiece The Last Quarter of the Moon (2005), taking Nord’s translation-oriented text analysis as a theoretical tool. The paper i…
View article: Multi-state luxury cruise ship seakeeping based on overlapping grids
Multi-state luxury cruise ship seakeeping based on overlapping grids Open
ObjectiveIn the design stage of a luxury cruise ship, in order to save costs, it is necessary to use the computational fluid dynamics (CFD) method to predict the seakeeping performance of the cruise ship under design. MethodThe research ob…
View article: Extraction of incoherent linear structured light stripe center on metal surface
Extraction of incoherent linear structured light stripe center on metal surface Open
采用线结构光法测量金属表面形貌时,由于受到金属表面光学特性和散斑噪声的影响,条纹中心的提取误差往往较大。为此,提出了一种非相干线结构光形貌测量方法,避免了散斑噪声的影响。通过分析该方法测量金属表面形貌时的条纹图像特点,提出一种适合非相干线结构光条纹的中心提取方法。该方法首先采用结合积分图像原理的自适应阈值分割算法,对原条纹图像进行分割。采用灰度重心法粗提取原条纹中心坐标,以该坐标为基准向条纹宽度方向延伸,从而确定阈值分割后条纹图的感兴趣区和背景区,并去除背景区的噪声。经中值…
View article: The Safety Automatic Monitoring System of Ancient Seawall Based on Vibration Control
The Safety Automatic Monitoring System of Ancient Seawall Based on Vibration Control Open
With the development of Chinese economy and society, infrastructure and engineering construction projects continue to increase. There are often construction projects such as wharfs, bridges and houses in the areas near the ancient seawall,…
View article: Uncertainty Analysis Applied to Predicting Water Inflow in Confined Water
Uncertainty Analysis Applied to Predicting Water Inflow in Confined Water Open
In order to predict the amount of water inflow accurately, define the corresponding water influx response quantitatively in the parameter variation interval, this paper used the interval uncertainty analysis method, combined with the non-p…
View article: Investigation of the Flow Field of a Ship in Planar Motion Mechanism Tests by the Vortex Identification Method
Investigation of the Flow Field of a Ship in Planar Motion Mechanism Tests by the Vortex Identification Method Open
Planar motion mechanism (PMM) tests provide a means of obtaining the hydrodynamic derivatives needed to assess ship maneuverability properties. In this paper, the self-developed computational fluid dynamic (CFD) solver based on the open so…
View article: Longitudinal peripheral blood transcriptional analysis of COVID-19 patients captures disease progression and reveals potential biomarkers
Longitudinal peripheral blood transcriptional analysis of COVID-19 patients captures disease progression and reveals potential biomarkers Open
COVID-19, caused by SARS-CoV-2, is an acute self-resolving disease in most of the patients, but some patients can develop a severe illness or even death. To characterize the host responses and identify potential biomarkers during disease p…
View article: Virtual Water Flow in the West–east Electricity Transmission Project in China
Virtual Water Flow in the West–east Electricity Transmission Project in China Open
Owing to the rapid development of the global economy, the demand for energy and water resources is the main global challenge in the 21 st century.This article focuses on the consumption and transfer of the water resources in China's West-E…
View article: Application Progress of Computational Fluid Dynamic Techniques for Complex Viscous Flows in Ship and Ocean Engineering
Application Progress of Computational Fluid Dynamic Techniques for Complex Viscous Flows in Ship and Ocean Engineering Open
Complex flow around floating structures is a highly nonlinear problem, and it is a typical feature in ship and ocean engineering. Traditional experimental methods and potential flow theory have limitations in predicting complex viscous flo…