Jiani Dong
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View article: CPSF3 Promotes Pre-mRNA Splicing and Prevents CircRNA Cyclization in Hepatocellular Carcinoma
CPSF3 Promotes Pre-mRNA Splicing and Prevents CircRNA Cyclization in Hepatocellular Carcinoma Open
CircRNAs are crucial in tumorigenesis and metastasis, and are comprehensively downregulated in hepatocellular carcinoma (HCC). Previous studies demonstrated that the back-splicing of circRNAs was closely related to 3′-end splicing. As a co…
View article: A DNAzyme-enhanced nonlinear hybridization chain reaction for sensitive detection of microRNA
A DNAzyme-enhanced nonlinear hybridization chain reaction for sensitive detection of microRNA Open
As a typical biomarker, the expression of microRNA is closely related to the occurrence of cancer. However, in recent years, the detection methods have had some limitations in the research and application of microRNAs. In this paper, an au…
View article: CPSF3 modulates the balance of circular and linear transcripts in hepatocellular carcinoma
CPSF3 modulates the balance of circular and linear transcripts in hepatocellular carcinoma Open
Background: CircRNAs play an important role in tumorigenesis and metastasis, and their expression is comprehensively downregulated in hepatocellular carcinoma (HCC). Previous studies have shown that the polyadenylation signal 1 is critical…
View article: Natural deep eutectic solvents as tailored and sustainable media for the extraction of five compounds from compound liquorice tablets and their comparison with conventional organic solvents
Natural deep eutectic solvents as tailored and sustainable media for the extraction of five compounds from compound liquorice tablets and their comparison with conventional organic solvents Open
A 1,4-butanediol–levulinic acid system was selected as a topgallant solvent and extraction parameters were optimized. NADES extracts exhibited higher extraction efficiency and in vitro antioxidant activities than conventional solvent extra…
View article: Effects of mongolian medicine <i>Terminalia chebula</i> Retz. on 6 CYP450 enzymes in rats.
Effects of mongolian medicine <i>Terminalia chebula</i> Retz. on 6 CYP450 enzymes in rats. Open
Terminalia chebula Retz. (TCR) is a medicinal material commonly used in Mongolian medicine. After consulting the literature at home and abroad, current research on TCR focuses on chemical composition, pharmacodynamics, and fingerpri…