Jiani Lu
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View article: Effects of Kinesio taping and extracorporeal shock wave therapy in combination with exercise in sarcopenic older adults: a study protocol of a double-blinded, randomized controlled trial
Effects of Kinesio taping and extracorporeal shock wave therapy in combination with exercise in sarcopenic older adults: a study protocol of a double-blinded, randomized controlled trial Open
Chinese Clinical Trial Registry (http//www.chictr.org.cn) register number ChiCTR2200064269.
View article: Exploring anti-SARS-CoV-2 natural products: dual-viral target inhibition by delphinidin and the anti-coronaviral efficacy of deapio platycodin D
Exploring anti-SARS-CoV-2 natural products: dual-viral target inhibition by delphinidin and the anti-coronaviral efficacy of deapio platycodin D Open
Qingfei Paidu decoction (QFPDD) has been extensively used in clinical treatments during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic. SARS-CoV-2 primarily invades host cells via its spike (S) protein binding to…
View article: Identifying Exifone as a Dual-Target Agent Targeting Both SARS-CoV-2 3CL Protease and the ACE2/S-RBD Interaction Among Clinical Polyphenolic Compounds
Identifying Exifone as a Dual-Target Agent Targeting Both SARS-CoV-2 3CL Protease and the ACE2/S-RBD Interaction Among Clinical Polyphenolic Compounds Open
The ongoing emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has led to resistance against multiple coronavirus disease 2019 (COVID-19) vaccines and therapeutic medications, making the development of effec…
View article: Exploring bifunctional molecules for anti-SARS-CoV-2 and anti-inflammatory activity through structure-based virtual screening, SAR investigation, and biological evaluation
Exploring bifunctional molecules for anti-SARS-CoV-2 and anti-inflammatory activity through structure-based virtual screening, SAR investigation, and biological evaluation Open
As new variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue to emerge, they raise increasing concerns about the efficacy of neutralizing antibodies and vaccines. This situation underscores the urgent need f…
View article: Joint Learning of Volume Scheduling and Order Placement Policies for Optimal Order Execution
Joint Learning of Volume Scheduling and Order Placement Policies for Optimal Order Execution Open
Order execution is an extremely important problem in the financial domain, and recently, more and more researchers have tried to employ reinforcement learning (RL) techniques to solve this challenging problem. There are a lot of difficulti…
View article: Novel Alkynylamide-Based Nonpeptidic Allosteric Inhibitors for SARS-CoV-2 3-Chymotrypsin-like Protease
Novel Alkynylamide-Based Nonpeptidic Allosteric Inhibitors for SARS-CoV-2 3-Chymotrypsin-like Protease Open
Although the coronavirus disease 2019 (COVID-19) crisis has passed, there remains a necessity for continuous efforts toward developing more targeted drugs and preparing for potential future virus attacks. Currently, most of the drugs recei…
View article: Longitudinal Dynamics of Immune Response in Occupational Populations Post COVID-19 Infection in the Changning District of Shanghai, China
Longitudinal Dynamics of Immune Response in Occupational Populations Post COVID-19 Infection in the Changning District of Shanghai, China Open
Monitoring the long-term changes in antibody and cellular immunity following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is crucial for understanding immune mechanisms that prevent reinfection. In March 2023, we …
View article: Promising natural products targeting protein tyrosine phosphatase <scp>SHP2</scp> for cancer therapy
Promising natural products targeting protein tyrosine phosphatase <span>SHP2</span> for cancer therapy Open
The development of Src homology‐2 domain containing protein tyrosine phosphatase‐2 (SHP2) inhibitors is a hot spot in the research and development of antitumor drugs, which may induce immunomodulatory effects in the tumor microenvironment …
View article: Methyl rosmarinate is an allosteric inhibitor of SARS-CoV-2 3 CL protease as a potential candidate against SARS-cov-2 infection
Methyl rosmarinate is an allosteric inhibitor of SARS-CoV-2 3 CL protease as a potential candidate against SARS-cov-2 infection Open
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been ongoing for more than three years and urgently needs to be addressed. Traditional Chinese medicine (TCM) presc…
View article: Priming transcranial direct current stimulation for improving hemiparetic upper limb in patients with subacute stroke: study protocol for a randomised controlled trial
Priming transcranial direct current stimulation for improving hemiparetic upper limb in patients with subacute stroke: study protocol for a randomised controlled trial Open
Introduction Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that modulates brain states by applying a weak electrical current to the brain cortex. Several studies have shown that anodal stimula…
View article: Selective photosynthesis of Z‐olefins through crystalline metal–organic cage‐initiated expeditious cascade reactions
Selective photosynthesis of Z‐olefins through crystalline metal–organic cage‐initiated expeditious cascade reactions Open
The semi‐hydrogenation of alkyne to form Z‐olefins with high conversion and high selectivity is still a huge challenge in the chemical industry. Moreover, flammable and explosive hydrogen as the common hydrogen source of this reaction incr…
View article: Examining the impact of perceived stress, anxiety, and resilience on depression among medical staff after COVID-19 quarantine: a chain mediation analysis
Examining the impact of perceived stress, anxiety, and resilience on depression among medical staff after COVID-19 quarantine: a chain mediation analysis Open
Introduction The COVID-19 pandemic and subsequent quarantine measures have led to a significant impact on mental health worldwide. Medical staff, in particular, have been exposed to high levels of stress due to their frontline work during …
View article: Synergistic Metal‐Nonmetal Active Sites in a Metal‐Organic Cage for Efficient Photocatalytic Synthesis of Hydrogen Peroxide in Pure Water
Synergistic Metal‐Nonmetal Active Sites in a Metal‐Organic Cage for Efficient Photocatalytic Synthesis of Hydrogen Peroxide in Pure Water Open
Photocatalytic synthesis of hydrogen peroxide (H 2 O 2 ) is a potential clean method, but the long distance between the oxidation and reduction sites in photocatalysts hinders the rapid transfer of photogenerated charges, limiting the impr…
View article: Genetic insight into population structure of Sino-Tibetan-speaking Yi People in Guizhou, Southwest China
Genetic insight into population structure of Sino-Tibetan-speaking Yi People in Guizhou, Southwest China Open
We collected 18 samples from 6 tribes of the Yi population (including 6 individuals with unknown tribes) from the Wumeng Mountain, Guizhou province. All participants gave informed consent and have a long-term resident history in the region…
View article: PLGA-PEG-fucoxanthin nanoparticles protect against ischemic stroke in vivo
PLGA-PEG-fucoxanthin nanoparticles protect against ischemic stroke in vivo Open
Fucoxanthin is the most abundant marine carotenoid derived from edible brown seaweeds and has been used as a functional ingredient for the treatment of obesity. However, poor brain bioavailability of fucoxanthin has limited its application…
View article: Design, synthesis and application of two-dimensional metal tellurides as high-performance electrode materials
Design, synthesis and application of two-dimensional metal tellurides as high-performance electrode materials Open
Multifunctional electrode materials with inherent conductivity have attracted extensive attention in recent years. Two-dimensional (2D) metal telluride nanomaterials are more promising owing to their strong metallic properties and unique p…
View article: Return-to-Work Predictions for Chinese Patients With Occupational Upper Extremity Injury: A Prospective Cohort Study
Return-to-Work Predictions for Chinese Patients With Occupational Upper Extremity Injury: A Prospective Cohort Study Open
Objective We created predictive models using machine learning algorithms for return-to-work (RTW) in patients with traumatic upper extremity injuries. Methods Data were obtained immediately before patient discharge and patients were follow…
View article: Optimization of onion Juice inhibiting white-blush in fresh-cutcarrots by response surface methodology
Optimization of onion Juice inhibiting white-blush in fresh-cutcarrots by response surface methodology Open
The effect of onion juice on the whitening of fresh-cut carrots during storage was explored to optimize the processing technology of fresh-cut carrots. Using fresh carrot and onion as raw materials and whiteness value as reference index, t…
View article: Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese
Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese Open
Chuanqing is an unrecognised ethnic group in Guizhou, southwest China. The genetic history of the Chuanqing people is hotly debated due to a lack of available genetic data. To infer the genetic structure and population history of the Chuan…
View article: The effect of inclination on lower extremity inter-joint coordination during treadmill walking
The effect of inclination on lower extremity inter-joint coordination during treadmill walking Open
Purpose/Hypothesis: Inclined walking is a challenging daily task in comparison with level walking. It requires specific control from central nervous system and exhibits increases in muscle activities and alternations of joint kinematics in…