Jianling Wang
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View article: Penfluridol enhances anti-tumor immunity in colorectal cancer by inducing proteasome-mediated degradation of PD-L1 via the activation of AMPK
Penfluridol enhances anti-tumor immunity in colorectal cancer by inducing proteasome-mediated degradation of PD-L1 via the activation of AMPK Open
View article: Ag2O-decorated poly(lanthanide–β-cyclodextrin) based on a silica microsphere with reversible photo-regeneration: Highly sensitive and broad-spectrum fluorescent sensing of tetracycline antibiotics
Ag2O-decorated poly(lanthanide–β-cyclodextrin) based on a silica microsphere with reversible photo-regeneration: Highly sensitive and broad-spectrum fluorescent sensing of tetracycline antibiotics Open
View article: Drought limits microplastic effects on soil greenhouse gas emissions by reducing microbial diversity
Drought limits microplastic effects on soil greenhouse gas emissions by reducing microbial diversity Open
Extreme droughts and microplastics (MPs) accumulation in agricultural soils threaten ecosystem sustainability. We examined the impact of MPs and drought stress on greenhouse gas (GHG) emissions, along with the transformation patterns of ca…
View article: Thyrotropin exacerbates insulin resistance by triggering macrophage inflammation in subclinical hypothyroidism
Thyrotropin exacerbates insulin resistance by triggering macrophage inflammation in subclinical hypothyroidism Open
View article: Serendipitous Recommendation with Multimodal LLM
Serendipitous Recommendation with Multimodal LLM Open
Conventional recommendation systems succeed in identifying relevant content but often fail to provide users with surprising or novel items. Multimodal Large Language Models (MLLMs) possess the world knowledge and multimodal understanding n…
View article: Genome-wide CRISPR screening identifies PHF8 as an effective therapeutic target for KRAS- or BRAF-mutant colorectal cancers
Genome-wide CRISPR screening identifies PHF8 as an effective therapeutic target for KRAS- or BRAF-mutant colorectal cancers Open
View article: Consolidation and Mechanical Properties of Continuous Carbon Fiber Reinforced Pa6 Rod Prepared Using a Novel Thermoplastic Pultrusion Technology with Prepreg Tapes
Consolidation and Mechanical Properties of Continuous Carbon Fiber Reinforced Pa6 Rod Prepared Using a Novel Thermoplastic Pultrusion Technology with Prepreg Tapes Open
View article: Hydrogen/solvent-free plastic valorization <i>via</i> loosely coordinated ruthenium sites steering selective aromatization
Hydrogen/solvent-free plastic valorization <i>via</i> loosely coordinated ruthenium sites steering selective aromatization Open
Ru atomic clusters optimize interactions with intermediates, lowering dehydrogenation and cyclization barriers, thereby enhancing catalytic efficiency and selectivity.
View article: SGSST: Scaling Gaussian Splatting StyleTransfer
SGSST: Scaling Gaussian Splatting StyleTransfer Open
Applying style transfer to a full 3D environment is a challenging task that has seen many developments since the advent of neural rendering. 3D Gaussian splatting (3DGS) has recently pushed further many limits of neural rendering in terms …
View article: Hygrothermal aging on the mechanical property and degradation mechanism of carbon fiber reinforced epoxy composites modified by nylon 6
Hygrothermal aging on the mechanical property and degradation mechanism of carbon fiber reinforced epoxy composites modified by nylon 6 Open
Nylon 6 (PA6) with excellent fracture toughness and hygrothermal resistance is added to the high-strength/modulus carbon fiber reinforced epoxy resin as a filler, which is expected to signally improve the thermal and mechanical properties.…
View article: Hygrothermal Aging on the Mechanical Property and Degradation Mechanism of Carbon Fiber Reinforced Epoxy Composites Modified by Nylon 6
Hygrothermal Aging on the Mechanical Property and Degradation Mechanism of Carbon Fiber Reinforced Epoxy Composites Modified by Nylon 6 Open
View article: Serum Amino Acids Changes in adolescent Diagnosed with Kashin-Beck Disease: A Study of Target Metabolomics
Serum Amino Acids Changes in adolescent Diagnosed with Kashin-Beck Disease: A Study of Target Metabolomics Open
Background Kashin-Beck disease ( KBD ) is a chronic degenerative osteoarthropathy with uncertain etiology. This study aims to identify variations in serum amino acids (AAs) between KBD adolescent and control adolescent and to investigate t…
View article: Feasibility Analysis of Polyurethane-Prepolymer-Modified Bitumen Used for Fully Reclaimed Asphalt Pavement (FRAP)
Feasibility Analysis of Polyurethane-Prepolymer-Modified Bitumen Used for Fully Reclaimed Asphalt Pavement (FRAP) Open
Asphalt pavement recycling technology with high reclaimed asphalt pavement (RAP) content has always been limited by unsatisfactory pavement performance and the rising cost of pavement materials. To address these challenges, polyurethane-pr…
View article: Promoting Residents’ Willingness to Recycle Electronic ICT Waste in China: An Empirical Study Using Conjoint Analysis
Promoting Residents’ Willingness to Recycle Electronic ICT Waste in China: An Empirical Study Using Conjoint Analysis Open
Initiated by the Chinese government to mitigate pollution arising from informal recycling, the Internet + Recycling model has been evolving and yielding significant results in China over the past few years. However, due to the large amount…
View article: The Optimized Catalytic Performance of Single‐Atom Catalysts by Incorporating Atomic Clusters or Nanoparticles: In‐Depth Understanding on Their Synergisms
The Optimized Catalytic Performance of Single‐Atom Catalysts by Incorporating Atomic Clusters or Nanoparticles: In‐Depth Understanding on Their Synergisms Open
The performance optimization of single‐atom catalysts (SACs) is important but remains challenging. Taking advantage of accompanying in situ formation of atomic clusters (ACs)/nanoparticles (NPs) during the preparation of SACs can be a prom…
View article: A primary research on male patients diagnosed as acute brucellosis with untargeted metabolomics technique
A primary research on male patients diagnosed as acute brucellosis with untargeted metabolomics technique Open
Background Brucellosis is a worldwide zoonotic disease through the consumption of unpasteurized dairy products, inhalation of infected aerosolized particles, and direct or indirect contact with infected animals. A timely and accurate diagn…
View article: The optimized Fenton-like activity of Fe single-atom sites by Fe atomic clusters–mediated electronic configuration modulation
The optimized Fenton-like activity of Fe single-atom sites by Fe atomic clusters–mediated electronic configuration modulation Open
The performance optimization of isolated atomically dispersed metal active sites is critical but challenging. Here, TiO 2 @Fe species-N-C catalysts with Fe atomic clusters (ACs) and satellite Fe-N 4 active sites were fabricated to initiate…
View article: The Value of Circulating Tumor Cells and Tumor Markers Detection in Lung Cancer Diagnosis
The Value of Circulating Tumor Cells and Tumor Markers Detection in Lung Cancer Diagnosis Open
Objective Circulating tumor cells are complete tumor cells with multi-scale analysis values that present a high potential for lung cancer diagnosis. To enhance the accuracy of lung cancer diagnosis, we detected circulating tumor cells by t…
View article: On Estimation of the Logarithm of the Mean Squared Prediction Error of A Mixed-effect Predictor
On Estimation of the Logarithm of the Mean Squared Prediction Error of A Mixed-effect Predictor Open
The mean squared prediction error (MSPE) has been used as an important measure of uncertainty in small area estimation.It is desirable to produce a second-order unbiased MSPE estimator, that is, the bias of the estimator is o(m -1 ), where…
View article: GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to paclitaxel by forming a vicious cycle with IGF1/IGF1R signaling pathway
GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to paclitaxel by forming a vicious cycle with IGF1/IGF1R signaling pathway Open
View article: Identification of SBP Gene Family and Analysis of Expression Patterns under salt stress in Quinoa 1
Identification of SBP Gene Family and Analysis of Expression Patterns under salt stress in Quinoa 1 Open
This study identified the SQUAMOSA Promoter Binding Proteins transcription factor SBP from the whole genome of Quinoa by analyzing the phylogenetic relationship, gene structure, chromosome location and gene replication, upstream cis-regula…
View article: Unraveling the Atomic-Level Vacancy Modulation in Cu9s5 for Nir-Driven Efficient Inhibition of Drug-Resistant Bacteria: Key Role of Cu Vacancy Position
Unraveling the Atomic-Level Vacancy Modulation in Cu9s5 for Nir-Driven Efficient Inhibition of Drug-Resistant Bacteria: Key Role of Cu Vacancy Position Open
View article: Chiral Squaramide Catalyzed Enantioselective Michael Addition of Cyclic 1,3-Diketones to <i>β</i>,<i>γ</i>-Unsaturated <i>α</i>-Keto Esters
Chiral Squaramide Catalyzed Enantioselective Michael Addition of Cyclic 1,3-Diketones to <i>β</i>,<i>γ</i>-Unsaturated <i>α</i>-Keto Esters Open
View article: Quantitative Evaluation of Emergency Shelters in Mountainous Areas Among Multiple Scenarios
Quantitative Evaluation of Emergency Shelters in Mountainous Areas Among Multiple Scenarios Open
View article: Single-atom doping in carbon black nanomaterials for photothermal antibacterial applications
Single-atom doping in carbon black nanomaterials for photothermal antibacterial applications Open
Summary: The growing problem of antimicrobial resistance has become a serious threat to human health. Loading single atoms onto carbon-based materials is a new strategy to develop environmentally friendly and stable photothermal antibacter…
View article: The 16S rRNA gene sequencing of gut microbiota in chickens infected with different virulent Newcastle disease virus
The 16S rRNA gene sequencing of gut microbiota in chickens infected with different virulent Newcastle disease virus Open
Background Newcastle disease virus (NDV) is pathogenic to chickens, which is characterized by dyspnea, diarrhea, nervous disorder and hemorrhages. However, the influence of different virulent NDV infection on the host gut microbiota compos…
View article: A New Product Development and Effect Analysis of Tinnitus Therapy Based on Pink Noise Tone
A New Product Development and Effect Analysis of Tinnitus Therapy Based on Pink Noise Tone Open
Sound therapy for tinnitus includes not only acclimatization therapy and masking therapy, but also music therapy. Traditional music therapy for tinnitus is mostly based on "white noise". This study attempts to introduce pink noise into the…
View article: ROS-Scavenging Nanomaterials to Treat Periodontitis
ROS-Scavenging Nanomaterials to Treat Periodontitis Open
The incidence of periodontitis is very high, and up to 45-50% of people are suffering from periodontitis. Periodontitis is caused by pathogens that invade teeth-supporting tissues such as gingiva, periodontal ligament, and alveolar bone. P…
View article: Cytochrome P450 2E1-deficient MRL+/+ mice are less susceptible to trichloroethene-mediated autoimmunity: Involvement of oxidative stress-responsive signaling pathways
Cytochrome P450 2E1-deficient MRL+/+ mice are less susceptible to trichloroethene-mediated autoimmunity: Involvement of oxidative stress-responsive signaling pathways Open
View article: Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer
Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer Open
In breast cancer, estrogen receptor alpha (ERα) positive cancer accounts for approximately 74% of all diagnoses, and in these settings, it is a primary driver of cell proliferation. Treatment of ERα positive breast cancer has long relied o…