Jianmin Huang
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View article: Liraglutide in Acute Minor Ischemic Stroke or High-Risk Transient Ischemic Attack With Type 2 Diabetes
Liraglutide in Acute Minor Ischemic Stroke or High-Risk Transient Ischemic Attack With Type 2 Diabetes Open
Importance Glucagon-like peptide–1 receptor agonists can reduce the risk of cardiovascular events in patients with high-risk type 2 diabetes (T2D). However, dedicated randomized clinical trials that evaluate their efficacy in acute ischemi…
View article: Case Report: Maribavir for refractory cytomegalovirus viremia after renal transplantation in a child with Schimke’s immune-osseous dysplasia
Case Report: Maribavir for refractory cytomegalovirus viremia after renal transplantation in a child with Schimke’s immune-osseous dysplasia Open
Cytomegalovirus (CMV) is a major opportunistic pathogen in recipients of solid organ transplantation. Maribavir, a pUL97 protein kinase inhibitor, was approved for the treatment of refractory post-transplant CMV infection in the US in 2021…
View article: Correction: Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression
Correction: Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression Open
View article: Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression
Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression Open
View article: Plasma fibronectin is a prognostic biomarker of disability in Parkinson’s disease: a prospective, multicenter cohort study
Plasma fibronectin is a prognostic biomarker of disability in Parkinson’s disease: a prospective, multicenter cohort study Open
View article: Identification of serum N-glycans signatures in three major gastrointestinal cancers by high-throughput N-glycome profiling
Identification of serum N-glycans signatures in three major gastrointestinal cancers by high-throughput N-glycome profiling Open
Serum N-glycome profile was differentially expressed in three major gastrointestinal cancers, providing a new clinical tool for cancer diagnosis and throwing a light upon the disease-specific molecular signatures.
View article: Identification of serum glycan signatures in three major gastrointestinal cancers by high-throughput N-glycome profiling
Identification of serum glycan signatures in three major gastrointestinal cancers by high-throughput N-glycome profiling Open
Background Alternative N-glycosylation of serum proteins has been observed in colorectal cancer (CRC), esophageal squamous cell carcinoma (ESCC) and gastric cancer (GC), while comparative study among those three major gastrointestinal canc…
View article: The impact and pathways of virtual faculty on the implementation behaviour of change in the physical education and health curriculum
The impact and pathways of virtual faculty on the implementation behaviour of change in the physical education and health curriculum Open
View article: Plasma Fibronectin is a Prognostic Biomarker of Disability in Parkinson's Disease: A Prospective, Multicenter Cohort Study
Plasma Fibronectin is a Prognostic Biomarker of Disability in Parkinson's Disease: A Prospective, Multicenter Cohort Study Open
View article: Theoretical logic, realistic review and promotion of physical education meta-verse teaching mode of co-construction, co-governance and sharing
Theoretical logic, realistic review and promotion of physical education meta-verse teaching mode of co-construction, co-governance and sharing Open
View article: S234: UPDATED CLINICAL RESULTS OF FIRST-IN-HUMAN STUDY OF CD19/BCMA DUAL-TARGETING FAST CAR-T GC012F FOR PATIENTS WITH RELAPSED/REFRACTORY B-CELL NON-HODGKIN’S LYMPHOMA
S234: UPDATED CLINICAL RESULTS OF FIRST-IN-HUMAN STUDY OF CD19/BCMA DUAL-TARGETING FAST CAR-T GC012F FOR PATIENTS WITH RELAPSED/REFRACTORY B-CELL NON-HODGKIN’S LYMPHOMA Open
Background: CD19-directed CAR-T cell therapy has been demonstrated to be a valuable treatment option for relapsed/refractory B-cell non-Hodgkin’s lymphoma (r/r B-NHL). It has been shown that 39% to 97% of clinical B-NHL samples also expres…
View article: CCR Translation on this Article from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer
CCR Translation on this Article from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer Open
CCR Translation on this Article from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer
View article: Data from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer
Data from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer Open
Purpose: Aberrant promoter methylation and genomic instability occur frequently during colorectal cancer development. CpG island methylator phenotype (CIMP) has been shown to associate with microsatellite instability, and BRAF
View article: CCR Translation on this Article from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer
CCR Translation on this Article from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer Open
CCR Translation on this Article from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer
View article: Data from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer
Data from CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer Open
Purpose: Aberrant promoter methylation and genomic instability occur frequently during colorectal cancer development. CpG island methylator phenotype (CIMP) has been shown to associate with microsatellite instability, and BRAF
View article: Validation of the EKFC equation for glomerular filtration rate estimation and comparison with the Asian-modified CKD-EPI equation in Chinese chronic kidney disease patients in an external study
Validation of the EKFC equation for glomerular filtration rate estimation and comparison with the Asian-modified CKD-EPI equation in Chinese chronic kidney disease patients in an external study Open
The overall performance of EKFC equation is acceptable. There is no clinically meaningful difference in the performance of the Asian-modified CKD-EPI and EKFC equations within the limits imposed by the small sample size.
View article: A 5-Year Longitudinal, Multicentre Validation Study Assessing the Prognostic Value of Plasma Fibronectin in a Cohort of Parkinson's Disease Participants
A 5-Year Longitudinal, Multicentre Validation Study Assessing the Prognostic Value of Plasma Fibronectin in a Cohort of Parkinson's Disease Participants Open
View article: Small noncoding RNA dysregulation is implicated in manganism in a rat model of methylcyclopentadienyl manganese tricarbonyl-induced unrepaired striatum damage
Small noncoding RNA dysregulation is implicated in manganism in a rat model of methylcyclopentadienyl manganese tricarbonyl-induced unrepaired striatum damage Open
The accumulation of excessively high manganese levels within the brain can contribute to a series of Parkinsonian symptoms referred to as manganism. The gasoline antiknock additive Methylcyclopentadienyl Manganese Tricarbonyl (MMT) is an e…
View article: Same-day single-dose <i>vs</i> large-volume split-dose regimens of polyethylene glycol for bowel preparation: A systematic review and meta-analysis
Same-day single-dose <i>vs</i> large-volume split-dose regimens of polyethylene glycol for bowel preparation: A systematic review and meta-analysis Open
Regardless of adjuvant laxative use, the (2 L/4 L) SSD PEG-based arm was considered equal or better than the large-volume (≥ 3 L) SpDs PEG regimen in terms of bowel cleanliness and tolerability. Patients that received low-volume (2 L) SSDs…
View article: Clinical and immunological characteristics of vaccinated patients with COVID-19
Clinical and immunological characteristics of vaccinated patients with COVID-19 Open
To the Editor: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a serious public health crisis threatening human health and survival worldwide.[1] Reportedly, laboratory charac…
View article: Retinoic acid induces differentiation of cochlear neural progenitor cells into hair cells
Retinoic acid induces differentiation of cochlear neural progenitor cells into hair cells Open
Introduction: Inner ear progenitor cells have the potential for multi-directional differentiation. Retinoic acid is an important requirement for the development of the inner ear. Blocking the Curtyr’s retinoic acid signaling pathway can si…
View article: The ensemble learning model is not better than the Asian modified CKD-EPI equation for glomerular filtration rate estimation in Chinese CKD patients in the external validation study
The ensemble learning model is not better than the Asian modified CKD-EPI equation for glomerular filtration rate estimation in Chinese CKD patients in the external validation study Open
View article: Retinoic acid induces differentiation of cochlear neural progenitor cells into hair cells
Retinoic acid induces differentiation of cochlear neural progenitor cells into hair cells Open
Retinoic acid can promote cochlear neural progenitor cells to differentiate into the hair cells.
View article: Comparative performance of FAS equation and Asian modified CKD-EPI in the determination of GFR in Chinese patients with CKD with the 99mTc-DTPA plasma clearance as the reference method
Comparative performance of FAS equation and Asian modified CKD-EPI in the determination of GFR in Chinese patients with CKD with the 99mTc-DTPA plasma clearance as the reference method Open
The FAS equation and the Asian modified CKD-EPI equation had similar performance in determining the glomerular filtration rate in the Chinese patients with chronic kidney disease. Both the FAS equation and Asian modified CKD-EPI can be a s…
View article: Comparative performance of FAS equation and Asian modified CKD-EPI in the determination of GFR in Chinese patients with CKD with the 99mTc-DTPA plasma clearance as the reference method
Comparative performance of FAS equation and Asian modified CKD-EPI in the determination of GFR in Chinese patients with CKD with the 99mTc-DTPA plasma clearance as the reference method Open
View article: Application of Multiplex Bisulfite PCR–Ligase Detection Reaction–Real-Time Quantitative PCR Assay in Interrogating Bioinformatically Identified, Blood-Based Methylation Markers for Colorectal Cancer
Application of Multiplex Bisulfite PCR–Ligase Detection Reaction–Real-Time Quantitative PCR Assay in Interrogating Bioinformatically Identified, Blood-Based Methylation Markers for Colorectal Cancer Open
View article: Prediction of blood-based biomarkers and subsequent design of bisulfite PCR-LDR-qPCR assay for breast cancer detection
Prediction of blood-based biomarkers and subsequent design of bisulfite PCR-LDR-qPCR assay for breast cancer detection Open
View article: Single‐molecule detection of cancer mutations using a novel PCR‐LDR‐qPCR assay
Single‐molecule detection of cancer mutations using a novel PCR‐LDR‐qPCR assay Open
Detection of low-abundance mutations in cell-free DNA is being used to identify early cancer and early cancer recurrence. Here, we report a new PCR-LDR-qPCR assay capable of detecting point mutations at a single-molecule resolution in the …
View article: A PHASE I STUDY OF THE BTK INHIBITOR ABIVERTINIB (AC0010) IN PATIENTS WITH RELAPSED OR REFRACTORY B-CELL LYMPHOMA
A PHASE I STUDY OF THE BTK INHIBITOR ABIVERTINIB (AC0010) IN PATIENTS WITH RELAPSED OR REFRACTORY B-CELL LYMPHOMA Open
View article: PF515 A PHASE I STUDY OF THE BTK INHIBITOR ABIVERTINIB (AC0010) IN PATIENTS WITH RELAPSED OR REFRACTORY B‐CELL LYMPHOMA
PF515 A PHASE I STUDY OF THE BTK INHIBITOR ABIVERTINIB (AC0010) IN PATIENTS WITH RELAPSED OR REFRACTORY B‐CELL LYMPHOMA Open
Background: Bruton's tyrosine kinase (BTK) is a clinically validated target for the treatment of B‐cell malignancies, including relapsed/refractory (R/R) mantle cell lymphoma (MCL), marginal zone lymphoma (MZL), chronic lymphocytic leukemi…