Jianping Qian
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View article: Prospective multicenter validation of preoperative plasma ceramides as novel predictive biomarkers for clinically relevant post-hepatectomy liver failure
Prospective multicenter validation of preoperative plasma ceramides as novel predictive biomarkers for clinically relevant post-hepatectomy liver failure Open
Background: Circulating ceramides (CERs) are associated with liver diseases and dysfunction. The utility of plasma CERs in predicting post-hepatectomy liver failure (PHLF) remains unclear. This study aimed to evaluate the clinical utility …
View article: Targeting the ceramidase ACER3 attenuates cholestasis in mice by mitigating bile acid overload via unsaturated ceramide-mediated LXRβ signaling transduction
Targeting the ceramidase ACER3 attenuates cholestasis in mice by mitigating bile acid overload via unsaturated ceramide-mediated LXRβ signaling transduction Open
View article: Seasonal Dynamics and Source Apportionment of Heavy Metals in Road Dust: A Case Study of Liuzhou, China
Seasonal Dynamics and Source Apportionment of Heavy Metals in Road Dust: A Case Study of Liuzhou, China Open
The spatial distribution and seasonal variation in heavy metal pollution in road dust in Liuzhou, China, were investigated. Road dust samples were collected during both drought and wet periods, and the concentrations of nine heavy metals—C…
View article: Fruits hidden by green: an improved YOLOV8n for detection of young citrus in lush citrus trees
Fruits hidden by green: an improved YOLOV8n for detection of young citrus in lush citrus trees Open
In order to address the challenges of inefficiency and insufficient accuracy in the manual identification of young citrus fruits during thinning processes, this study proposes a detection methodology using the you only look once for comple…
View article: Activation of Sphingomyelin Phosphodiesterase 3 in Liver Regeneration Impedes the Progression of Colorectal Cancer Liver Metastasis Via Exosome-Bound Intercellular Transfer of Ceramides
Activation of Sphingomyelin Phosphodiesterase 3 in Liver Regeneration Impedes the Progression of Colorectal Cancer Liver Metastasis Via Exosome-Bound Intercellular Transfer of Ceramides Open
SMPD3-produced exosomal CER constitutes a critical anti-CRLM mechanism in LR to impede CRLM, offering the promise of using CER as a therapeutic agent to prevent the recurrence of CRLM after PH.
View article: Dynamic Nomogram for predicting the severity of acute pancreatitis in adults and Decision Curve analysis: a single-center retrospective study
Dynamic Nomogram for predicting the severity of acute pancreatitis in adults and Decision Curve analysis: a single-center retrospective study Open
Objective Acute pancreatitis (AP) is a common and unpredictable disease. Severity stratification and prognostic prediction play an important role in reducing the mortality of AP and improving its prognosis in the early stage. We aimed to e…
View article: Strategic Issues of Monitoring and Information Services of Agricultural Water and Land Resources in China
Strategic Issues of Monitoring and Information Services of Agricultural Water and Land Resources in China Open
As cropland and water resources are most valuable, the rational development and utilization of agricultural water and land resources are crucial for national food, ecological, and resource security. Therefore, obtaining timely and accurate…
View article: Spatial and temporal distribution and utilization of water resources in Guangxi and suggestions for their protection
Spatial and temporal distribution and utilization of water resources in Guangxi and suggestions for their protection Open
The spatial distribution characteristics of surface water and underground water resources in Guangxi were discussed. The temporal variation trend of surface water and groundwater resources and the present situation of water resources explo…
View article: Nonalcoholic steatohepatitis critically rewires the ischemia/reperfusion-induced dysregulation of cardiolipins and sphingolipids in mice
Nonalcoholic steatohepatitis critically rewires the ischemia/reperfusion-induced dysregulation of cardiolipins and sphingolipids in mice Open
The I/R-induced dysregulation of CL and SL were critically rewired by NASH, which might potentially mediate the aggressive I/R injury in NASH livers.
View article: Ceramides and sphingosine-1-phosphate mediate the distinct effects of M1/M2-macrophage infusion on liver recovery after hepatectomy
Ceramides and sphingosine-1-phosphate mediate the distinct effects of M1/M2-macrophage infusion on liver recovery after hepatectomy Open
Post-hepatectomy liver dysfunction is a life-threatening morbidity that lacks efficient therapy. Bioactive lipids involved in macrophage polarization crucially regulate tissue injury and regeneration. Herein, we investigate the key bioacti…
View article: Integrated Proteomics and Bioinformatics to Identify Potential Prognostic Biomarkers in Hepatocellular Carcinoma
Integrated Proteomics and Bioinformatics to Identify Potential Prognostic Biomarkers in Hepatocellular Carcinoma Open
All in all, we found that these eight genes might be the novel potential prognostic biomarkers for HCC and also provide promising insights into the pathogenesis of HCC at the molecular level.
View article: ACOX2 is a prognostic marker and impedes the progression of hepatocellular carcinoma via PPARα pathway
ACOX2 is a prognostic marker and impedes the progression of hepatocellular carcinoma via PPARα pathway Open
View article: Correction: Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress
Correction: Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress Open
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View article: Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress
Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress Open
View article: Activation of Sphingosine Kinase 1/Sphingosine-1-Phosphate Pathway Protects Nonalcoholic Fatty Liver from Ischemia/Reperfusion Injury by Alleviating Oxidative Stress in Hepatocytes
Activation of Sphingosine Kinase 1/Sphingosine-1-Phosphate Pathway Protects Nonalcoholic Fatty Liver from Ischemia/Reperfusion Injury by Alleviating Oxidative Stress in Hepatocytes Open
View article: <p>miR-942 promotes proliferation and metastasis of hepatocellular carcinoma cells by inhibiting RRM2B</p>
miR-942 promotes proliferation and metastasis of hepatocellular carcinoma cells by inhibiting RRM2B Open
miR-942 may serve as a potential biomarker for HCC and its inhibitor may be a therapeutic agent for the treatment of this deadly disease.
View article: Expression of microRNA-30c via lentivirus vector inhibits the proliferation and enhances the sensitivity of highly aggressive ccRCC Caki-1 cells to anticancer agents
Expression of microRNA-30c via lentivirus vector inhibits the proliferation and enhances the sensitivity of highly aggressive ccRCC Caki-1 cells to anticancer agents Open
The clear cell renal cell carcinoma (ccRCC) is one of the most fatal urologic tumors, and the prognosis remains very poor for advanced or metastatic ccRCC. This study reveals the roles of microRNA (miR)-30c in regulating a highly aggressiv…
View article: Apple Fruit Diameter and Length Estimation by Using the Thermal and Sunshine Hours Approach and Its Application to the Digital Orchard Management Information System
Apple Fruit Diameter and Length Estimation by Using the Thermal and Sunshine Hours Approach and Its Application to the Digital Orchard Management Information System Open
In apple cultivation, simulation models may be used to monitor fruit size during the growth and development process to predict production levels and to optimize fruit quality. Here, Fuji apples cultivated in spindle-type systems were used …