Jianqiang Tang
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View article: Highly dispersed tetragonal zirconia nanoparticles: Facile hydrothermal synthesis and their photocatalytic property
Highly dispersed tetragonal zirconia nanoparticles: Facile hydrothermal synthesis and their photocatalytic property Open
View article: Neoadjuvant combination immunotherapy for colorectal cancer: clinical and molecular predictors of pathological complete response and safety assessment
Neoadjuvant combination immunotherapy for colorectal cancer: clinical and molecular predictors of pathological complete response and safety assessment Open
Neoadjuvant combination immunotherapy resulted in a favorable pCR rate in patients with CRC. Young age, pretreatment CEA level, TMB level, clinical stage, lymph node metastasis, MSI, MMR, and pole status can be used as indicators of the ef…
View article: Clinical value of fluorescence laparoscopic surgery on anastomotic leakage prevention in ultra-low rectal cancer: real-world multicenter retrospective evidence with neoadjuvant chemoradiotherapy stratification
Clinical value of fluorescence laparoscopic surgery on anastomotic leakage prevention in ultra-low rectal cancer: real-world multicenter retrospective evidence with neoadjuvant chemoradiotherapy stratification Open
Fluorescence-guided laparoscopic surgery reduces anastomotic leakage and improves outcomes in low rectal cancer, especially after chemoradiotherapy, by enhancing surgical precision and recovery.
View article: Fluorescence lymph node mapping using ICG improves lateral lymph node dissection for mid-low rectal cancer: a propensity score-matched cohort
Fluorescence lymph node mapping using ICG improves lateral lymph node dissection for mid-low rectal cancer: a propensity score-matched cohort Open
ICG-LLND improved lateral lymph node harvest, particularly obturator lymph nodes, and shortened postoperative hospital stay without increasing complications. This technique may enhance surgical outcomes in patients requiring lymph node dis…
View article: Comprehensive fragmentation of cell-free repetitive DNA for enhanced cancer detection in plasma
Comprehensive fragmentation of cell-free repetitive DNA for enhanced cancer detection in plasma Open
Background Repetitive elements account for a large proportion of the human genome and undergo alterations during early tumorigenesis. However, the exclusive fragmentation pattern of DNA-derived cell-free repetitive elements (cfREs) remains…
View article: A new EGFR and c-Met bispecific NIR-II fluorescent probe for visualising colorectal cancer and metastatic lymph nodes
A new EGFR and c-Met bispecific NIR-II fluorescent probe for visualising colorectal cancer and metastatic lymph nodes Open
View article: Fluorescence Lymph Node Mapping Using ICG Improves Lateral Lymph Node Dissection for Mid-Low Rectal Cancer: A Propensity Score-Matched Cohort
Fluorescence Lymph Node Mapping Using ICG Improves Lateral Lymph Node Dissection for Mid-Low Rectal Cancer: A Propensity Score-Matched Cohort Open
Background: Patients with lateral lymph node metastasis (LLNM) present particular challenges for both diagnosis and treatment. This study aimed to assess whether indocyanine green (ICG) assisted lymph node mapping with near-infrared imagin…
View article: PAR2 deficiency impairs antitumor immunity and attenuates anti-PD1 efficacy in colorectal cancer
PAR2 deficiency impairs antitumor immunity and attenuates anti-PD1 efficacy in colorectal cancer Open
A T cell-inflamed tumor microenvironment is predictive of better prognosis and clinical response to immunotherapy. Proteinase-activated receptor 2 (PAR2), a member of G-protein coupled receptors is involved in inflammatory process and the …
View article: Gut microbiota, immune cell, colorectal cancer association mediators: a Mendelian randomization study
Gut microbiota, immune cell, colorectal cancer association mediators: a Mendelian randomization study Open
View article: Patient selection and operative strategies for laparoscopic intersphincteric resection without diverting stoma
Patient selection and operative strategies for laparoscopic intersphincteric resection without diverting stoma Open
BACKGROUND Diverting stoma (DS) is routinely proposed in intersphincteric resection for ultralow rectal cancer, but it is associated with increased stoma-related complications and economic burden. Appropriate patient selection and operativ…
View article: Cryopreservation Strategies for Poultry Semen: A Comprehensive Review of Techniques and Applications
Cryopreservation Strategies for Poultry Semen: A Comprehensive Review of Techniques and Applications Open
Poultry semen preservation is crucial for sustaining genetic diversity, improving production efficiency, and facilitating various breeding initiatives. This review underscores the importance and challenges associated with different preserv…
View article: Evaluating the predictive value of endoscopic findings for residual colorectal cancer following neoadjuvant combination immunotherapy
Evaluating the predictive value of endoscopic findings for residual colorectal cancer following neoadjuvant combination immunotherapy Open
BACKGROUND Endoscopy allows for the direct observation of primary tumor characteristics and responses after neoadjuvant treatment. However, reports on endoscopic evaluation following neoadjuvant immunotherapy remain limited. AIM To examine…
View article: Prediction of Lymph Node Metastasis in Colorectal Cancer Using Intraoperative Fluorescence Multi-Modal Imaging
Prediction of Lymph Node Metastasis in Colorectal Cancer Using Intraoperative Fluorescence Multi-Modal Imaging Open
The diagnosis of lymph node metastasis (LNM) is essential for colorectal cancer (CRC) treatment. The primary method of identifying LNM is to perform frozen sections and pathologic analysis, but this method is labor-intensive and time-consu…
View article: Endoscopic and imaging evaluations of the primary tumor response in patients with proficient mismatch repair colorectal cancer treated with neoadjuvant combination immunotherapy
Endoscopic and imaging evaluations of the primary tumor response in patients with proficient mismatch repair colorectal cancer treated with neoadjuvant combination immunotherapy Open
Background Neoadjuvant combination immunotherapy is a potential treatment option for patients with proficient mismatch repair/microsatellite stable colorectal cancer. Preoperative screening via endoscopy and imaging exams could help identi…
View article: A Comparison of the Cecal Microbiota between the Infection and Recovery Periods in Chickens with Different Susceptibilities to Eimeria tenella
A Comparison of the Cecal Microbiota between the Infection and Recovery Periods in Chickens with Different Susceptibilities to Eimeria tenella Open
To investigate the effect of Eimeria tenella (E. tenella) infection on the cecal microbiota, resistant and susceptible families were screened out based on the coccidiosis resistance evaluation indexes after E. tenella infection. Subsequent…
View article: Chinese expert consensus on the pelvic exenteration for primary rectal cancer beyond total mesorectal excision planes and locally recurrent rectal cancer
Chinese expert consensus on the pelvic exenteration for primary rectal cancer beyond total mesorectal excision planes and locally recurrent rectal cancer Open
Pelvic exenteration is often required for primary rectal cancer beyond total mesorectal excision (PRC-bTME) and locally recurrent rectal cancer (LRRC). Some patients with radical resection can achieve long-term survival, but they need to f…
View article: Nomogram for predicting the probability of rectal anastomotic re-leakage after stoma closure: a retrospective study
Nomogram for predicting the probability of rectal anastomotic re-leakage after stoma closure: a retrospective study Open
Background In this study, we aimed to identify the risk factors in patients with rectal anastomotic re-leakage and develop a prediction model to predict the probability of rectal anastomotic re-leakage after stoma closure. Methods This stu…
View article: Prognostic stratification of patients with pT4bN0M0 colorectal cancer following multivisceral resection: a multi-institutional case series analysis
Prognostic stratification of patients with pT4bN0M0 colorectal cancer following multivisceral resection: a multi-institutional case series analysis Open
Background: Colorectal cancer (CRC) patients with stage pT4b are a complex group as they show differences in tumor-infiltrated organs. Patients with the same stage often exhibit differences in prognosis after multivisceral resection (MVR).…
View article: Nomogram for predicting the probability of rectal anastomotic re-leakage after diverting stoma: A retrospective study
Nomogram for predicting the probability of rectal anastomotic re-leakage after diverting stoma: A retrospective study Open
Background: In this study, we aimed to identify the risk factors in patients with rectal anastomotic re-leakage and develop a prediction model to predict the probability of rectal anastomotic re-leakage after diverting stoma. Methods: This…
View article: A novel classification of posterior pelvic exenteration to assess prognosis in female patients with locally advanced primary rectal cancer: a retrospective cohort study from China PelvEx collaborative
A novel classification of posterior pelvic exenteration to assess prognosis in female patients with locally advanced primary rectal cancer: a retrospective cohort study from China PelvEx collaborative Open
Purpose Surgical techniques and the prognosis of posterior pelvic exenteration for locally advanced primary rectal cancer in female patients pose challenges that need to be addressed. Therefore, we investigated the short-term and survival …
View article: Neoadjuvant Combination Immunotherapy for Colorectal Cancer: Clinical and Molecular Predictors of Pathological Complete Response and Safety Assessment
Neoadjuvant Combination Immunotherapy for Colorectal Cancer: Clinical and Molecular Predictors of Pathological Complete Response and Safety Assessment Open
Purpose To identify the clinical and molecular factors that effectively predict pathological complete response (pCR) and assess the safety of patients receiving neoadjuvant combination immunotherapy. Materials and Methods This retrospectiv…
View article: A Novel Classification of Posterior Pelvic Exenteration to Assess Prognosis in Female Patients with Locally Advanced Primary Rectal Cancer: A Retrospective Cohort Study from China PelvEx Collaborative
A Novel Classification of Posterior Pelvic Exenteration to Assess Prognosis in Female Patients with Locally Advanced Primary Rectal Cancer: A Retrospective Cohort Study from China PelvEx Collaborative Open
Purpose Surgical techniques and the prognosis of posterior pelvic exenteration for locally advanced primary rectal cancer in female patients pose challenges that warrant additional assessment. Therefore, we compared short-term and survival…
View article: Short-term and long-term outcomes of Laparoscopic surgery for locally recurrent rectal cancer: A propensity score-matched cohort study
Short-term and long-term outcomes of Laparoscopic surgery for locally recurrent rectal cancer: A propensity score-matched cohort study Open
Background Radical surgery remains the primary option for locally recurrent rectal cancer (LRRC) as it has the potential to considerably extend the patient's lifespan. At present, the effectiveness of laparoscopic surgery for LRRC remains …
View article: Short-term and long-term outcomes of intracorporeal anastomosis in laparoscopic segmental left colectomy for splenic flexure cancer – a multicenter retrospective cohort study of 342 cases
Short-term and long-term outcomes of intracorporeal anastomosis in laparoscopic segmental left colectomy for splenic flexure cancer – a multicenter retrospective cohort study of 342 cases Open
Introduction: While intracorporeal anastomosis (IA) has been widely used in totally laparoscopic right colectomy, its application in laparoscopic segmental left colectomy for splenic flexure cancer remains underexplored, particularly in la…
View article: Short- and long-term results of open <i>vs</i> laparoscopic multisegmental resection and anastomosis for synchronous colorectal cancer located in separate segments
Short- and long-term results of open <i>vs</i> laparoscopic multisegmental resection and anastomosis for synchronous colorectal cancer located in separate segments Open
Indocyanine green (ICG) is a water-soluble fluorescent dye that is minimally toxic and widely used in gastrointestinal surgery. ICG facilitates anatomical identification of structures (e.g., ureters), assessment of lymph nodes, biliary map…
View article: Persistent descending mesocolon as a vital risk factor for anastomotic failure and prolonged operative time for sigmoid colon and rectal cancers
Persistent descending mesocolon as a vital risk factor for anastomotic failure and prolonged operative time for sigmoid colon and rectal cancers Open
Background The diagnostic criteria and effect of persistent descending mesocolon (PDM) on sigmoid and rectal cancers (SRCs) remain controversial. This study aims to clarify PDM patients' radiological features and short-term surgical result…
View article: Long-term outcomes and failure patterns after laparoscopic intersphincteric resection in ultralow rectal cancers
Long-term outcomes and failure patterns after laparoscopic intersphincteric resection in ultralow rectal cancers Open
This study confirmed the oncological safety of LsISR for ultralow rectal cancer. Poor differentiation, (y)pT3 stage, and lymph node metastasis are independent risk factors for treatment failure after LsISR, and thus patients with these fac…
View article: Comprehensive analysis of gut microbiome and host transcriptome in chickens after Eimeria tenella infection
Comprehensive analysis of gut microbiome and host transcriptome in chickens after Eimeria tenella infection Open
Background Coccidiosis is an intestinal parasitic disease caused by Eimeria protozoa, which endangers the health and growth of animals, and causes huge economic losses to the poultry industry worldwide every year. Studies have shown that p…
View article: Persistent descending mesocolon as a vital risk factor for anastomotic failure and prolonged operative time for sigmoid colon and rectal cancers
Persistent descending mesocolon as a vital risk factor for anastomotic failure and prolonged operative time for sigmoid colon and rectal cancers Open
Background The diagnostic criteria and effect of persistent descending mesocolon (PDM) on sigmoid and rectal cancers (SRCs) remain controversial. This study aims to clarify PDM patients' radiological features and short-term surgical result…
View article: Surgical outcomes of left hemicolon sparing resection versus extensive resection in treating synchronous colorectal cancer involving the right-sided colon and sigmoid colon or rectum
Surgical outcomes of left hemicolon sparing resection versus extensive resection in treating synchronous colorectal cancer involving the right-sided colon and sigmoid colon or rectum Open