Jianqiao Ruan
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View article: Huangqi fuling decoction inhibits the invasion and metastasis of gastric cancer via the TNF signaling pathway
Huangqi fuling decoction inhibits the invasion and metastasis of gastric cancer via the TNF signaling pathway Open
Gastric cancer (GC) is a prevalent digestive tract malignancy, and Huangqi Fuling decoction (HF) has shown potential in enhancing immune function and exhibiting anti-GC activity. However, its mechanisms remain unclear. This study utilized …
View article: Huangqi fuling decoction inhibits the invasion and metastasis of gastric cancer via the TNF signaling pathway
Huangqi fuling decoction inhibits the invasion and metastasis of gastric cancer via the TNF signaling pathway Open
Gastric cancer (GC) is a prevalent digestive tract malignancy, and Huangqi Fuling decoction (HF) has shown potential in enhancing immune function and exhibiting anti-GC activity. However, its mechanisms remain unclear. This study utilized …
View article: The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells
The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells Open
Mutation of isocitrate dehydrogenase 1 promotes the migration, invasion, and angiogenesis of glioma cells, through its effects on the BMP2-driven Smad signaling pathway. In addition, BMP2 altered the transcriptional patterns of mutIDH1 gli…
View article: The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells
The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells Open
Purpose This study investigated the effect of an isocitrate dehydrogenase 1 (IDH1) mutation (mutIDH1) on the invasion and angiogenesis of human glioma U87 cells. Methods Doxycycline was used to induce the expression of mutIDH1 in U87 cells…