Jianxiang Zhang
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View article: Author correction to “Self-illuminating liposome-derived in situ triggerable photodynamic therapy combining radionuclide therapy for synergistic treatment of lung cancer” [Acta Pharm Sin B 15 (2025) 4973–4994]
Author correction to “Self-illuminating liposome-derived in situ triggerable photodynamic therapy combining radionuclide therapy for synergistic treatment of lung cancer” [Acta Pharm Sin B 15 (2025) 4973–4994] Open
View article: The H3K4 methyltransferase KMT2D is an essential cofactor for GATA1 at erythroid gene enhancers
The H3K4 methyltransferase KMT2D is an essential cofactor for GATA1 at erythroid gene enhancers Open
Gene expression during cellular differentiation is coordinated by combinatorial interactions between transcription factors (TFs) and cofactors at promoters and enhancers. The “master TF” GATA1 coordinates gene transcription in a subset of …
View article: Optimized fertilization and fruit load regulate yield, quality, and nutrient uptake in pomelo trees
Optimized fertilization and fruit load regulate yield, quality, and nutrient uptake in pomelo trees Open
View article: Targeting neutrophil factor NCF1 with multi-bioactive conjugate therapy: a breakthrough in preventing preterm birth
Targeting neutrophil factor NCF1 with multi-bioactive conjugate therapy: a breakthrough in preventing preterm birth Open
View article: Orally deliverable biomimetic nucleic acid therapies for targeted treatment of atherosclerosis
Orally deliverable biomimetic nucleic acid therapies for targeted treatment of atherosclerosis Open
Accumulating evidence has demonstrated that nucleic acid-based therapies are promising for atherosclerosis. However, nearly all nucleic acid delivery systems developed for atherosclerosis necessitate injection, which results in rapid elimi…
View article: Identifying fibroblast-derived sFRP2 as a therapeutic target and engineering siRNA therapy for uterine scarring
Identifying fibroblast-derived sFRP2 as a therapeutic target and engineering siRNA therapy for uterine scarring Open
View article: Advanced nanotherapies for precision treatment of inflammatory lung diseases
Advanced nanotherapies for precision treatment of inflammatory lung diseases Open
View article: Self-illuminating liposome-derived in situ triggerable photodynamic therapy combining radionuclide therapy for synergistic treatment of lung cancer
Self-illuminating liposome-derived in situ triggerable photodynamic therapy combining radionuclide therapy for synergistic treatment of lung cancer Open
View article: Development and validation of a risk nomogram predicting pneumothorax requiring chest tube placement post-percutaneous CT-guided lung biopsy
Development and validation of a risk nomogram predicting pneumothorax requiring chest tube placement post-percutaneous CT-guided lung biopsy Open
View article: Single-cell RNA sequencing-guided engineering of mitochondrial therapies for intervertebral disc degeneration by regulating mtDNA/SPARC-STING signaling
Single-cell RNA sequencing-guided engineering of mitochondrial therapies for intervertebral disc degeneration by regulating mtDNA/SPARC-STING signaling Open
View article: CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis
CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis Open
Background CTCF is considered as the most essential transcription factor regulating chromatin architecture and gene expression. However, genome-wide impact of CTCF on erythropoiesis has not been extensively investigated. Results Using a st…
View article: Pathophysiology‐Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain (Adv. Sci. 8/2025)
Pathophysiology‐Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain (Adv. Sci. 8/2025) Open
Combination Nanoanalgesic for Neuropathic Pain In article number 2405483, Yue Zhou, Jianxiang Zhang, and co‐workers report a combination nanoanalgesic composed of inflammation‐resolving nanomicelles and an analgesic peptide targeting the c…
View article: Study on the Chemical Composition and Multidrug Resistance Reversal Activity of Euphorbia uralensis (Euphorbiaceae)
Study on the Chemical Composition and Multidrug Resistance Reversal Activity of Euphorbia uralensis (Euphorbiaceae) Open
Euphorbia uralensis belongs to the family Euphorbiaceae and is widely distributed in northern Xinjiang, making it a characteristic plant of the region in Xinjiang, China. The chemical composition and biological activity of Euphorbia uralen…
View article: Pathophysiology‐Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain
Pathophysiology‐Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain Open
Neuropathic pain, one of the most refractory pain diseases, remains a formidable medical challenge. There is still an unmet demand for effective and safe therapies to address this condition. Herein, a rat model of nerve injury‐induced neur…
View article: An Osteoimmunomodulatory Biopatch Potentiates Stem Cell Therapies for Bone Regeneration by Simultaneously Regulating IL‐17/Ferroptosis Signaling Pathways
An Osteoimmunomodulatory Biopatch Potentiates Stem Cell Therapies for Bone Regeneration by Simultaneously Regulating IL‐17/Ferroptosis Signaling Pathways Open
Currently, there are still great challenges in promoting bone defect healing, a common health problem affecting millions of people. Herein an osteoimmunity‐regulating biopatch capable of promoting stem cell‐based therapies for bone regener…
View article: Immune Dysregulation in SARS-CoV-2 patients coinfected with Mycobacterium tuberculosis (Mtb) or HIV in China
Immune Dysregulation in SARS-CoV-2 patients coinfected with Mycobacterium tuberculosis (Mtb) or HIV in China Open
Background SARS-CoV-2 infections usually cause immune dysregulation in the human body. Studies of immunological changes resulting from coinfections with Mycobacterium tuberculosis ( Mtb ) or HIV are limited. Methods We conducted a retrospe…
View article: A Nomogram to Predict Pneumothorax Requiring Chest Tube Placement following Percutaneous CT-guided Lung Biopsy
A Nomogram to Predict Pneumothorax Requiring Chest Tube Placement following Percutaneous CT-guided Lung Biopsy Open
Background Pneumothorax requiring chest tube after CT-guided transthoracic lung biopsy is one of the common complications, and the required hospital stay after chest tube placement represents an added clinical risk to patients and cost to …
View article: RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein HOXA9
RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein HOXA9 Open
Background The oncogenic protein HOXA9 plays a critical role in leukemia transformation and maintenance, and its aberrant expression is a hallmark of most aggressive acute leukemia. Although inhibiting the upstream regulators of HOXA9 has …
View article: Enhanced thermal conductivity and reduced thermal resistance in carbon fiber-based thermal interface materials with vertically aligned structure
Enhanced thermal conductivity and reduced thermal resistance in carbon fiber-based thermal interface materials with vertically aligned structure Open
A sandwich-structured thermal interface material featuring vertically aligned carbon fibers and liquid metal-modified layers for enhanced thermal conductivity and reduced contact resistance in electronic devices.
View article: Anti‐Inflammatory Nanotherapies Based on Bioactive Cyclodextrin Materials
Anti‐Inflammatory Nanotherapies Based on Bioactive Cyclodextrin Materials Open
Despite remarkable advances in understanding the mechanisms underlying inflammation, the currently available anti‐inflammatory therapies have many limitations, such as poor efficacies, low selectivity, and severe adverse effects. Bioactive…
View article: Trade-offs and synergies of ecosystem services and their threshold effects in the largest tableland of the Loess Plateau
Trade-offs and synergies of ecosystem services and their threshold effects in the largest tableland of the Loess Plateau Open
Trade-offs and synergies in ecosystem services (ESs) are subject to considerable uncertainty due to different spatial and temporal scales. Smooth changes in ESs at different scales may cause discontinuous changes in trade-offs and synergie…
View article: Simultaneous percutaneous microwave ablation and biopsy for highly suspected malignant pulmonary nodules: a retrospective cohort study
Simultaneous percutaneous microwave ablation and biopsy for highly suspected malignant pulmonary nodules: a retrospective cohort study Open
Synchronous PB and MWA for PNs is a safe and effective strategy that can decrease bleeding, PED, the hospitalization stay, and costs.
View article: Functional Microgel Enables Effective Delivery and Colonization of Probiotics for Treating Colitis
Functional Microgel Enables Effective Delivery and Colonization of Probiotics for Treating Colitis Open
ADVERTISEMENT RETURN TO ARTICLES ASAPPREVFirst ReactionsNEXTFunctional Microgel Enables Effective Delivery and Colonization of Probiotics for Treating ColitisBingyu ChenBingyu ChenWomen and Children's Hospital, Chongqing Medical University…
View article: POS1164 CLINICAL OUTCOMES OF ANCA-ASSOCIATED VASCULITIS PATIENTS RECEIVING RITUXIMAB INDUCTION AND MAINTENANCE THERAPY: SYSTEMATIC REVIEW AND META-ANALYSIS OF LARGE OBSERVATIONAL STUDIES
POS1164 CLINICAL OUTCOMES OF ANCA-ASSOCIATED VASCULITIS PATIENTS RECEIVING RITUXIMAB INDUCTION AND MAINTENANCE THERAPY: SYSTEMATIC REVIEW AND META-ANALYSIS OF LARGE OBSERVATIONAL STUDIES Open
View article: Luminescence Nanoprobes for Drug Screening, Pharmaceutical Analysis, and Therapeutic Evaluations
Luminescence Nanoprobes for Drug Screening, Pharmaceutical Analysis, and Therapeutic Evaluations Open
Luminescence nanoprobes have been extensively investigated for many biomedical applications, ranging from cell/tissue imaging, real‐time monitoring pathophysiological changes, drug discovery, bioassays, image‐guided surgery, and therapeuti…
View article: Intrinsically bioactive and biomimetic nanoparticle-derived therapies alleviate asthma by regulating multiple pathological cells
Intrinsically bioactive and biomimetic nanoparticle-derived therapies alleviate asthma by regulating multiple pathological cells Open
View article: Iterative learning tracking control for second‐order nonlinear hyperbolic impulsive partial differential systems
Iterative learning tracking control for second‐order nonlinear hyperbolic impulsive partial differential systems Open
This paper studies the iterative learning control (ILC) for a class of second‐order nonlinear hyperbolic impulsive partial differential systems. Firstly, to follow the discontinuous desired output, a P‐type learning law is adopted, and suf…
View article: Cold-induced inhibition of photosynthesis-related genes integrated by a TOP6 complex in rice mesophyll cells
Cold-induced inhibition of photosynthesis-related genes integrated by a TOP6 complex in rice mesophyll cells Open
Photosynthesis is the most temperature-sensitive process in the plant kingdom, but how the photosynthetic pathway responds during low-temperature exposure remains unclear. Herein, cold stress (4°C) induced widespread damage in the form DNA…
View article: Large-Scale Production of Boron Nitride Nanosheets for Flexible Thermal Interface Materials with Highly Thermally Conductive and Low Dielectric Constant
Large-Scale Production of Boron Nitride Nanosheets for Flexible Thermal Interface Materials with Highly Thermally Conductive and Low Dielectric Constant Open
View article: Sandwich Structured Thermal Interface Materials with High Thermal Conductivity
Sandwich Structured Thermal Interface Materials with High Thermal Conductivity Open