Jianxiong Xu
YOU?
Author Swipe
View article: Influence of the safety technical specification for electric bicycles on consumer purchase behavior: evidence from social media analysis
Influence of the safety technical specification for electric bicycles on consumer purchase behavior: evidence from social media analysis Open
The ‘Safety Technical Specification for Electric Bicycles’ (GB 17761-2018) has been in effect for over six years, yet its influence on consumer purchase behavior remains unclear. This study examines public perceptions of the specification …
View article: Correction: Effects of microbe-derived antioxidants on growth performance, hepatic oxidative stress, mitochondrial function and cell apoptosis in weaning piglets
Correction: Effects of microbe-derived antioxidants on growth performance, hepatic oxidative stress, mitochondrial function and cell apoptosis in weaning piglets Open
View article: Integrated multi-omics reveals the ITGB2-IL2RB-NK axis in promoting papillary thyroid carcinoma progression and immune microenvironment crosstalk
Integrated multi-omics reveals the ITGB2-IL2RB-NK axis in promoting papillary thyroid carcinoma progression and immune microenvironment crosstalk Open
Introduction: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, with some cases exhibiting aggressive features and therapeutic resistance. Although dysregulated protein interaction networks and immune microenvironmen…
View article: New therapeutic targets and mechanisms of papillary thyroid carcinoma identified by multi-omics analysis
New therapeutic targets and mechanisms of papillary thyroid carcinoma identified by multi-omics analysis Open
Through multi-omics analysis, we identified new potential therapeutic targets for papillary thyroid carcinoma and investigated their possible underlying mechanisms affecting PTC.
View article: Parity-Associated Differences in the Antioxidants and Fecal Microbiota of Bactrian Camels
Parity-Associated Differences in the Antioxidants and Fecal Microbiota of Bactrian Camels Open
Camels survive in deserts through unique, adapted metabolic and immunological processes that are normally lethal to other species. Antioxidants and the gastrointestinal microbiota play major roles in redox homeostasis, yet they remain unex…
View article: Evaluation of the enzymatic hydrolysis of sargassum mixed with fish protein hydrolysis product as an alternative protein source in shrimp feed, from the perspectives of growth performance, amino acid composition, antioxidant capacity and endoplasmic reticulum stress
Evaluation of the enzymatic hydrolysis of sargassum mixed with fish protein hydrolysis product as an alternative protein source in shrimp feed, from the perspectives of growth performance, amino acid composition, antioxidant capacity and endoplasmic reticulum stress Open
View article: Effect of microbe‐derived antioxidants on intestinal oxidative stress, NLRP3 inflammasome, morphologic structure, and growth performance in weanling piglets
Effect of microbe‐derived antioxidants on intestinal oxidative stress, NLRP3 inflammasome, morphologic structure, and growth performance in weanling piglets Open
Weaning stress induces pigs oxidative stress, which decreases growth performance, causes intestinal damage, and increases diarrhea and death in piglets. Microbe‐derived antioxidants (MA) have an antioxidant and immune‐modulatory role, but …
View article: N-Acetyl Cysteine Inhibits Weaning Stress-Induced Intestinal Cell Cycle Arrest in Piglets through Decreasing ERK, JNK, and p38 Phosphorylation
N-Acetyl Cysteine Inhibits Weaning Stress-Induced Intestinal Cell Cycle Arrest in Piglets through Decreasing ERK, JNK, and p38 Phosphorylation Open
View article: Correction: Effects of microbe-derived antioxidants on growth performance, hepatic oxidative stress, mitochondrial function and cell apoptosis in weaning piglets
Correction: Effects of microbe-derived antioxidants on growth performance, hepatic oxidative stress, mitochondrial function and cell apoptosis in weaning piglets Open
View article: Transcriptome and targeted metabolome analysis of lipid profiles, nutrients compositions and volatile compounds in longissimus dorsi of different pig breeds
Transcriptome and targeted metabolome analysis of lipid profiles, nutrients compositions and volatile compounds in longissimus dorsi of different pig breeds Open
Objective: Improving meat quality is important for commercial production and breeding. The molecular mechanism of intramuscular fat (IMF) deposition and meat characteristics require further study.Methods: This study aimed to study the mech…
View article: Effects of microbe-derived antioxidants on growth performance, hepatic oxidative stress, mitochondrial function and cell apoptosis in weaning piglets
Effects of microbe-derived antioxidants on growth performance, hepatic oxidative stress, mitochondrial function and cell apoptosis in weaning piglets Open
View article: Regulatory Effects of Maternal Intake of Microbial-Derived Antioxidants on Colonization of Microbiota in Breastmilk and That of Intestinal Microbiota in Offspring
Regulatory Effects of Maternal Intake of Microbial-Derived Antioxidants on Colonization of Microbiota in Breastmilk and That of Intestinal Microbiota in Offspring Open
In this study, sixteen Sprague Dawley (SD) female rats and eight SD male rats were co-housed to mate. Pregnant SD female rats were fed with a control diet or an MA diet. Breast milk, maternal ileum, and intestinal samples of the offspring …
View article: Correlation between genotypes of Orientia tsutsugamushi and clinical characteristics of patients with scrub typhus in Guangzhou, China
Correlation between genotypes of Orientia tsutsugamushi and clinical characteristics of patients with scrub typhus in Guangzhou, China Open
Objective: To explore the correlation between genotypes of Orientia ( O. ) tsutsugamushi and clinical characteristics of scrub typhus patients. Methods: Clinical data of patients with scrub typhus admitted to different types of medical ins…
View article: Genetically predicted 91 circulating inflammatory proteins in relation to risk of urological malignancies: a Mendelian randomization study
Genetically predicted 91 circulating inflammatory proteins in relation to risk of urological malignancies: a Mendelian randomization study Open
Our findings suggest that certain plasma proteins may be involved in the development of urological malignancies. Mendelian randomization provides a useful framework for investigating causal relationships between inflammatory proteins and u…
View article: Microbe-Derived Antioxidants Protect IPEC-1 Cells from H2O2-Induced Oxidative Stress, Inflammation and Tight Junction Protein Disruption via Activating the Nrf2 Pathway to Inhibit the ROS/NLRP3/IL-1β Signaling Pathway
Microbe-Derived Antioxidants Protect IPEC-1 Cells from H2O2-Induced Oxidative Stress, Inflammation and Tight Junction Protein Disruption via Activating the Nrf2 Pathway to Inhibit the ROS/NLRP3/IL-1β Signaling Pathway Open
Oxidative stress can induce inflammation and tight junction disruption in enterocytes. The initiation of inflammation is thought to commence with the activation of the ROS/NLRP3/IL-1β signaling pathway, marking a crucial starting point in …
View article: Changes in Fecal Microbiome Associated with Parity in Lactating Bactrian Camels
Changes in Fecal Microbiome Associated with Parity in Lactating Bactrian Camels Open
To characterize the fecal microbiota of lactating Bactrian camels, this study employed a random selection of camels, assigning them to three groups: the first parity group, the third parity group, and the fifth parity group. The fecal micr…
View article: Biomechanics-mediated endocytosis in atherosclerosis
Biomechanics-mediated endocytosis in atherosclerosis Open
Biomechanical forces, including vascular shear stress, cyclic stretching, and extracellular matrix stiffness, which influence mechanosensitive channels in the plasma membrane, determine cell function in atherosclerosis. Being highly associ…
View article: Coupled single-cell and bulk RNA-seq analysis reveals the engulfment role of endothelial cells in atherosclerosis
Coupled single-cell and bulk RNA-seq analysis reveals the engulfment role of endothelial cells in atherosclerosis Open
View article: Remodeling of Hepatic Glucose Metabolism in Response to Early Weaning in Piglets
Remodeling of Hepatic Glucose Metabolism in Response to Early Weaning in Piglets Open
This study aimed to investigate the dynamic changes in hepatic glucose metabolism in response to early weaning. A total of 60 piglets were randomly selected and weaned at 21 days old. Six piglets were slaughtered on the weaning day (d0) an…
View article: Epidemiology and characteristics of identified early mpox cases in Guangdong Province, China: Implications for prevention and control
Epidemiology and characteristics of identified early mpox cases in Guangdong Province, China: Implications for prevention and control Open
In June 2023, the 2022 global mpox (monkeypox) outbreak began to affect Guangdong Province, one of the first regions in mainland China to report mpox cases. By July 10, 2023, 93 mpox cases had been reported in Guangdong Province. This stud…
View article: Mitochondria in endothelial cells angiogenesis and function: current understanding and future perspectives
Mitochondria in endothelial cells angiogenesis and function: current understanding and future perspectives Open
View article: A novel role for YPEL2 in mediating endothelial cellular senescence via the p53/p21 pathway
A novel role for YPEL2 in mediating endothelial cellular senescence via the p53/p21 pathway Open
Yippee-like 2 (YPEL2) is expressed in tissues and organs enriched in vascular networks, such as heart, kidney, and lung. However, the roles of YPEL2 in endothelial cell senescence and the expression of YPEL2 in atherosclerotic plaques have…
View article: Microbe-Derived Antioxidants Alleviate Liver and Adipose Tissue Lipid Disorders and Metabolic Inflammation Induced by High Fat Diet in Mice
Microbe-Derived Antioxidants Alleviate Liver and Adipose Tissue Lipid Disorders and Metabolic Inflammation Induced by High Fat Diet in Mice Open
Obesity induces lipodystrophy and metabolic inflammation. Microbe-derived antioxidants (MA) are novel small-molecule nutrients obtained from microbial fermentation, and have anti-oxidation, lipid-lowering and anti-inflammatory effects. Whe…
View article: Research on the Sustainable Development of Enterprises That Evoke Industrial Heritage—A Case Study of Taoxichuan
Research on the Sustainable Development of Enterprises That Evoke Industrial Heritage—A Case Study of Taoxichuan Open
This paper takes Taoxichuan Cultural and Creative Street as a case study. It explores how enterprises activate the value of “industrial heritage” resources and achieve sustainable development from the perspective of affordance theory. Rese…
View article: Exploring the Characteristics of Burkholderia Gladioli Pathovar Cocovenenans: Growth, Bongkrekic Acid Production, and Potential Risks of Food Contamination in Wet Rice Noodles and Vermicelli
Exploring the Characteristics of Burkholderia Gladioli Pathovar Cocovenenans: Growth, Bongkrekic Acid Production, and Potential Risks of Food Contamination in Wet Rice Noodles and Vermicelli Open
View article: Surveillance of Vaccination Coverage of Inactivated Influenza Vaccines and Allergic Rash Adverse Events Following Immunization for Children From 6 Manufacturers
Surveillance of Vaccination Coverage of Inactivated Influenza Vaccines and Allergic Rash Adverse Events Following Immunization for Children From 6 Manufacturers Open
The composition of influenza vaccines is updated annually. To ensure vaccine safety, the coverage and adverse events following immunization (AEFI) of 6 manufacturers of trivalent inactivated influenza vaccine (TIV3) need to be evaluated. I…
View article: Shear stress regulation of nanoparticle uptake in vascular endothelial cells
Shear stress regulation of nanoparticle uptake in vascular endothelial cells Open
Nanoparticles (NPs) hold tremendous targeting potential in cardiovascular disease and regenerative medicine, and exciting clinical applications are coming into light. Vascular endothelial cells (ECs) exposure to different magnitudes and pa…
View article: Berberine Regulation of Cellular Oxidative Stress, Apoptosis and Autophagy by Modulation of m6A mRNA Methylation through Targeting the Camk1db/ERK Pathway in Zebrafish-Hepatocytes
Berberine Regulation of Cellular Oxidative Stress, Apoptosis and Autophagy by Modulation of m6A mRNA Methylation through Targeting the Camk1db/ERK Pathway in Zebrafish-Hepatocytes Open
Berberine (BBR) ameliorates cellular oxidative stress, apoptosis and autophagy induced by lipid metabolism disorder, however, the molecular mechanism associated with it is not well known. To study the mechanism, we started with m6A methyla…
View article: Microbe-Derived Antioxidants Reduce Lipopolysaccharide-Induced Inflammatory Responses by Activating the Nrf2 Pathway to Inhibit the ROS/NLRP3/IL-1β Signaling Pathway
Microbe-Derived Antioxidants Reduce Lipopolysaccharide-Induced Inflammatory Responses by Activating the Nrf2 Pathway to Inhibit the ROS/NLRP3/IL-1β Signaling Pathway Open
Inflammation plays an important role in the innate immune response, yet overproduction of inflammation can lead to a variety of chronic diseases associated with the innate immune system; therefore, modulation of the excessive inflammatory …
View article: Flammulina velutipes Mycorrhizae Attenuate High Fat Diet-Induced Lipid Disorder, Oxidative Stress and Inflammation in the Liver and Perirenal Adipose Tissue of Mice
Flammulina velutipes Mycorrhizae Attenuate High Fat Diet-Induced Lipid Disorder, Oxidative Stress and Inflammation in the Liver and Perirenal Adipose Tissue of Mice Open
Flammulina velutipes (FV) is edible mushroom that has nutritional and medicinal values. FV mycorrhizae, the by-products of FV, are an abundant source and receive less attention. The objective of this study was to investigate the compositio…