Jianyong Han
YOU?
Author Swipe
View article: Performance of anticorrosive coatings for photovoltaic PHC pipe piles in brine environments of saline-alkali tidal flats
Performance of anticorrosive coatings for photovoltaic PHC pipe piles in brine environments of saline-alkali tidal flats Open
This study was conducted on an integrated wind-solar-storage-transmission base project located in a saline-alkali tidal flat area. The brine formation mechanism in saline-alkali tidal flats was revealed, and the chemical composition of the…
View article: Tracing and Capturing the Epiblast Pluripotency of Sheep Preimplantation Embryos
Tracing and Capturing the Epiblast Pluripotency of Sheep Preimplantation Embryos Open
Capturing different pluripotent state stem cells from epiblast in vitro helps understand embryonic development and provides invaluable cell sources for basic research and regenerative medicine. Sheep are not only one of the most important …
View article: Growing meat on autoclaved vegetables with biomimetic stiffness and micro-patterns
Growing meat on autoclaved vegetables with biomimetic stiffness and micro-patterns Open
View article: Elucidation of the pluripotent potential of bovine embryonic lineages facilitates the establishment of formative stem cell lines
Elucidation of the pluripotent potential of bovine embryonic lineages facilitates the establishment of formative stem cell lines Open
The establishment of epiblast-derived pluripotent stem cells (PSCs) from cattle, which are important domestic animals that provide humans with milk and meat while also serving as bioreactors for producing valuable proteins, poses a challen…
View article: Elucidation of the pluripotent potential of bovine embryonic lineages facilitates the establishment of formative stem cell lines
Elucidation of the pluripotent potential of bovine embryonic lineages facilitates the establishment of formative stem cell lines Open
The establishment of epiblast-derived pluripotent stem cells (PSCs) from cattle, which are important domestic animals that provide humans with milk and meat while also serving as bioreactors for producing valuable proteins, poses a challen…
View article: Growing meat on vegetables: plants with natural biomimetic micro-patterns as edible meat-engineering scaffolds
Growing meat on vegetables: plants with natural biomimetic micro-patterns as edible meat-engineering scaffolds Open
Cultured meat needs edible bio-scaffolds that provide not only an appropriate growth milieu for muscle and adipose cells, but also biomimetic microstructures to sculpt tissue architecture. Current meat-engineering technologies struggle to …
View article: Characteristics and control techniques of soft rock tunnel lining cracks in high geo-stress environments: Case study of Wushaoling tunnel group
Characteristics and control techniques of soft rock tunnel lining cracks in high geo-stress environments: Case study of Wushaoling tunnel group Open
A high geo-stress environment severely damages tunnel structures owing to the large deformation of the surrounding rock, thereby threatening their safety. In this study, the Wushaoling highway tunnel group, which passes through a high geo-…
View article: Generation of three-dimensional meat-like tissue from stable pig epiblast stem cells
Generation of three-dimensional meat-like tissue from stable pig epiblast stem cells Open
Cultured meat production has emerged as a breakthrough technology for the global food industry with the potential to reduce challenges associated with environmental sustainability, global public health, animal welfare, and competition for …
View article: Generation of three-dimensional skeletal muscle tissue as cultured meat from stable pig epiblast stem cells
Generation of three-dimensional skeletal muscle tissue as cultured meat from stable pig epiblast stem cells Open
Cultured meat (CM) production has emerged as a breakthrough technology for the global food industry, with the potential to reduce challenges associated with environmental sustainability, global public health, animal welfare, and competitio…
View article: Generation of stable integration‐free pig induced pluripotent stem cells under chemically defined culture condition
Generation of stable integration‐free pig induced pluripotent stem cells under chemically defined culture condition Open
Genome integration‐free pig induced pluripotent stem cells (iPSCs) bring tremendous value in pre‐clinical testing of regenerative medicine, as well as conservation and exploitation of endangered or rare local pig idioplasmatic resources. H…
View article: <i>Nanos3</i> knockout pigs to model transplantation and reconstruction of the germline
<i>Nanos3</i> knockout pigs to model transplantation and reconstruction of the germline Open
The anatomy and physiological characteristics of pigs are closer to those of humans than those of other non-primate animals. Therefore, pigs are considered excellent models for xenotransplantation and disease modelling.1 Several pig models…
View article: scm6A-seq reveals single-cell landscapes of the dynamic m6A during oocyte maturation and early embryonic development
scm6A-seq reveals single-cell landscapes of the dynamic m6A during oocyte maturation and early embryonic development Open
View article: Bearing capacity of driven pile and determination of inhomogeneous mudstone around the pile
Bearing capacity of driven pile and determination of inhomogeneous mudstone around the pile Open
Whether the inhomogeneity of mudstone foundation leads to abnormal bearing capacity of the driven pile remains controversial. This study introduces the standard penetration test hammering number and needle penetration strength for quantita…
View article: Construction Technology of Pipe Jacking Method through Underground Obstacles
Construction Technology of Pipe Jacking Method through Underground Obstacles Open
View article: Generation and characterization of stable pig pregastrulation epiblast stem cell lines
Generation and characterization of stable pig pregastrulation epiblast stem cell lines Open
Pig epiblast-derived pluripotent stem cells are considered to have great potential and broad prospects for human therapeutic model development and livestock breeding. Despite ongoing attempts since the 1990s, no stably defined pig epiblast…
View article: METTL3-mediated mRNA N6-methyladenosine is required for oocyte and follicle development in mice
METTL3-mediated mRNA N6-methyladenosine is required for oocyte and follicle development in mice Open
View article: XLOC-040580, a Novel lncRNA, Modulates Porcine Zygote Activation Progress
XLOC-040580, a Novel lncRNA, Modulates Porcine Zygote Activation Progress Open
Background: Long noncoding RNAs (lncRNAs) play an important role in porcine preimplantation embryonic development, but the regulatory mechanism of lncRNAs during zygote activation (ZGA) remains unclear.Methods: We analyzed the transcriptom…
View article: Mthfd2 Modulates Mitochondrial Function and DNA Repair to Maintain the Pluripotency of Mouse Stem Cells
Mthfd2 Modulates Mitochondrial Function and DNA Repair to Maintain the Pluripotency of Mouse Stem Cells Open
The pluripotency of stem cells determines their developmental potential. While the pluripotency states of pluripotent stem cells are variable and interconvertible, the mechanisms underlying the acquisition and maintenance of pluripotency r…
View article: A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG
A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG Open
View article: Additional file 6 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG
Additional file 6 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG Open
: Table S3. Differentially expressed genes (DEGs) identified using RNA-Seq data obtained from NANOG tdTomato knock-in positive PC-iPS cells vs. WT PC-iPS cells. (log2[fold-change ≥1]; adjusted p-value ≤0.05).
View article: Additional file 10 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG
Additional file 10 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG Open
: Table S6. KEGG pathway enrichment analysis for differentially expressed genes (DEGs) identified using RNA-Seq data obtained from NANOG tdTomato knock-in positive PC-iPS cells treated with Activin A or SB431542.
View article: Additional file 7 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG
Additional file 7 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG Open
: Table S4. KEGG pathway enrichment analysis for differentially expressed genes identified using RNA-Seq data obtained from NANOG tdTomato knock-in positive PC-iPS cells vs. WT PC-iPS cells.
View article: Additional file 9 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG
Additional file 9 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG Open
: Table S5. Differentially expressed genes (DEGs) identified using RNA-Seq data obtained from NANOG tdTomato knock-in positive PC-iPS cells treated with Activin A or SB431542. (log2[fold-change ≥1]; adjusted p-value ≤0.05).
View article: Additional file 4 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG
Additional file 4 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG Open
: Table S2. Detail of genes expression of clustering Nanog, pEPS and embryos.
View article: Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells
Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells Open
View article: Highlights for special issue on &#8220;Large Animal Stem Cells&#8221;
Highlights for special issue on “Large Animal Stem Cells” Open
Biological techniques such as stem cell culture, somatic cell reprogramming and gene editing are important for the large animal breeding.Also, these techniques can produce large animal models, which hold great potential for developing dise…
View article: Additional file 6: of Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system
Additional file 6: of Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system Open
Table S4. GO enrichment of differentially expressed genes. (XLS 1166 kb)
View article: Additional file 7: of Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system
Additional file 7: of Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system Open
Table S5. KEGG enrichment of differentially expressed genes. (XLS 25 kb)
View article: Additional file 4: of Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system
Additional file 4: of Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system Open
Table S2. The expression levels (RPKM) from RNAseq analysis of PC-iPS and PEF-iPS cells. (XLS 1109 kb)
View article: Additional file 5: of Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system
Additional file 5: of Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system Open
Table S3. Differential expression genes between PC-iPS and PEF-iPS cells. (XLS 2135 kb)