Jianzheng Cen
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View article: 20 years of experience with the Fontan procedure: Risk factors for adverse outcomes
20 years of experience with the Fontan procedure: Risk factors for adverse outcomes Open
The staged Fontan strategy was associated with reduced early mortality but did not confer significant benefits on long-term outcomes. Patients with heterotaxy were at an increased risk of late Fontan failure, highlighting the need for tail…
View article: Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis
Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis Open
Considerable heterogeneity in inflammatory response phenotypes among individuals may lead to significant differences in the clinical effectiveness of prophylactic corticosteroid interventions. Thus, developing personalized treatment strate…
View article: Plasma thrombin-antithrombin complex as a candidate biomarker for coronary slow flow
Plasma thrombin-antithrombin complex as a candidate biomarker for coronary slow flow Open
Background Coronary slow flow (CSF), characterized by delayed coronary perfusion without significant coronary artery stenosis, remains a diagnostic challenge due to its elusive pathophysiology. This retrospective study aimed to evaluate th…
View article: An engineered hypoxia-response promoter for human umbilical cord-derived mesenchymal stem cell-based therapeutics
An engineered hypoxia-response promoter for human umbilical cord-derived mesenchymal stem cell-based therapeutics Open
Myocardial infarction, characterized by insufficient blood supply to the heart, leads to ischemia and hypoxia of myocardial tissues, causing injury and decreased cardiac function. Despite improvements in pharmaceutical and interventional t…
View article: Composite Additive Manufacturing for Suspended Microelectrode Arrays: Advancing Oriented Myocardial Tissue Culturing and Electrophysiological Sensing
Composite Additive Manufacturing for Suspended Microelectrode Arrays: Advancing Oriented Myocardial Tissue Culturing and Electrophysiological Sensing Open
View article: Research trends in vascular chips from 2012 to 2022: a bibliometrix and visualized analysis
Research trends in vascular chips from 2012 to 2022: a bibliometrix and visualized analysis Open
Objective The vascular chip has emerged as a significant research tool, garnering increasing interest and exploration. We utilize bibliometric techniques to analyze literature from the Web of Science (WOS) database, focusing on core journa…
View article: Architecture design and advanced manufacturing of heart-on-a-chip: scaffolds, stimulation and sensors
Architecture design and advanced manufacturing of heart-on-a-chip: scaffolds, stimulation and sensors Open
Heart-on-a-chip (HoC) has emerged as a highly efficient, cost-effective device for the development of engineered cardiac tissue, facilitating high-throughput testing in drug development and clinical treatment. HoC is primarily used to crea…
View article: Outcomes of Rehabilitation Strategies for Pulmonary Atresia with Ventricular Septal Defect: A Single Center’s Experience
Outcomes of Rehabilitation Strategies for Pulmonary Atresia with Ventricular Septal Defect: A Single Center’s Experience Open
Background: Both systemic-to-pulmonary shunt and right ventricle-pulmonary artery (RV-PA) connection are extensively applied to initially rehabilitate the pulmonary artery in pulmonary atresia with the ventricle septal defect (PA/VSD). How…
View article: Perioperative corticosteroids for reducing postoperative complications following esophagectomy: an updated systematic review and meta-analysis
Perioperative corticosteroids for reducing postoperative complications following esophagectomy: an updated systematic review and meta-analysis Open
View article: Myogenin Regulates DUSP13 to Inhibit Apoptosis Induced by Reactive Oxygen Species
Myogenin Regulates DUSP13 to Inhibit Apoptosis Induced by Reactive Oxygen Species Open
Background: Myogenin is well known as a crucial transcription factor in skeletal muscle development, yet its other biological functions remain unexplored. Previous research showed that myogenin suppresses apoptosis induced by angiotensin I…
View article: Bronchus compression is a predictor for reobstruction in coarctation with hypoplastic arch repair
Bronchus compression is a predictor for reobstruction in coarctation with hypoplastic arch repair Open
OBJECTIVES The surgical treatment of coarctation of aorta with hypoplastic aortic arch (CoA/HAA) was challenging to achieve long-lasting arch patency. We reviewed early and late outcomes in our centre and identified predictors for arch reo…
View article: Long-term outcomes of pulmonary atresia with ventricular septal defect by different initial rehabilitative surgical age
Long-term outcomes of pulmonary atresia with ventricular septal defect by different initial rehabilitative surgical age Open
Background There is a lack of evidence guiding the surgical timing selection in pulmonary atresia with ventricular septal defect. This study aims to compare the long-term outcomes of different initial rehabilitative surgical ages in patien…
View article: Characteristics and risk factors for postoperative mortality in children with congenital heart disease (CHD): a retrospective cross-sectional study
Characteristics and risk factors for postoperative mortality in children with congenital heart disease (CHD): a retrospective cross-sectional study Open
Objectives: We performed a retrospective cross-sectional study to determine the characteristics and risk factors for postoperative mortality in children who underwent CHD surgery. Design: A cross-sectional retrospective study. Setting: Gua…
View article: Surgical aortic valvuloplasty is a better primary intervention for isolated congenital aortic stenosis in children with bicuspid aortic valve than balloon aortic valvuloplasty
Surgical aortic valvuloplasty is a better primary intervention for isolated congenital aortic stenosis in children with bicuspid aortic valve than balloon aortic valvuloplasty Open
SAV and BAV achieved excellent survival and freedom from reintervention in patients with isolated CAS. SAV performed better in PAG reduction and maintenance. For patients with bicuspid AoV morphology, SAV was the preferred choice.
View article: Epidemiological characteristics and trends in postoperative death in children with congenital heart disease (CHD): a single-center retrospective study from 2005 to 2020
Epidemiological characteristics and trends in postoperative death in children with congenital heart disease (CHD): a single-center retrospective study from 2005 to 2020 Open
View article: A large ascending aortic aneurysm in a 2-year-old boy with Loeys-Dietz syndrome
A large ascending aortic aneurysm in a 2-year-old boy with Loeys-Dietz syndrome Open
View article: Surgical repair of unilateral absence of pulmonary artery in children with pulmonary hypertension: a single-center retrospective study
Surgical repair of unilateral absence of pulmonary artery in children with pulmonary hypertension: a single-center retrospective study Open
Early PA reconstruction may effectively alleviate pulmonary hypertension in children with UAPA. The "two-segment" technique is safe and can facilitate potential redo pulmonary arterioplasty. Anticoagulation and antiplatelet therapy, as wel…
View article: Long-term outcomes of primary aortic valve repair in children with congenital aortic stenosis – 15-year experience at a single center
Long-term outcomes of primary aortic valve repair in children with congenital aortic stenosis – 15-year experience at a single center Open
Background Studies on the long-term outcomes of children with congenital aortic stenosis who underwent primary aortic repair are limited. We reviewed the long-term outcomes of children who underwent aortic valve (AoV) repair at our center.…
View article: Anomalous left coronary artery from the pulmonary artery: Outcomes and management of mitral valve
Anomalous left coronary artery from the pulmonary artery: Outcomes and management of mitral valve Open
Objective Use of concomitant mitral valve repair remains controversial in the anomalous left coronary artery from the pulmonary artery (ALCAPA) with mitral regurgitation (MR). This study aimed to evaluate postoperative mitral valve functio…
View article: A Novel 3D Visualized Operative Procedure in the Single-Stage Complete Repair With Unifocalization of Pulmonary Atresia With Ventricular Septal Defect and Major Aortopulmonary Collateral Arteries
A Novel 3D Visualized Operative Procedure in the Single-Stage Complete Repair With Unifocalization of Pulmonary Atresia With Ventricular Septal Defect and Major Aortopulmonary Collateral Arteries Open
Objectives Pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries (PA/VSD/MAPCAs) is a relatively rare, complex, and heterogeneous congenital heart disease. As one of the effective treatments, the mid…
View article: Accumulated Epinephrine Dose is Associated With Acute Kidney Injury Following Resuscitation in Adult Cardiac Arrest Patients
Accumulated Epinephrine Dose is Associated With Acute Kidney Injury Following Resuscitation in Adult Cardiac Arrest Patients Open
The goal of this study was to investigate the association between total epinephrine dosage during resuscitation and acute kidney injury after return of spontaneous circulation in patients with cardiac arrest. We performed a secondary analy…
View article: 3D-bioprinted vascular scaffold with tunable mechanical properties for simulating and promoting neo-vascularization
3D-bioprinted vascular scaffold with tunable mechanical properties for simulating and promoting neo-vascularization Open
Alternative artificial vessels with tissue-matching mechanical and biological performance have been continuously taking great attention in bioengineering. However, it is challenging to take into account both mechanical and biological prope…
View article: Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience
Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience Open
View article: Bilateral Pulmonary Arteries Reconstruction for Correction of Tetralogy of Fallot with Unilateral Absence of the Pulmonary Artery
Bilateral Pulmonary Arteries Reconstruction for Correction of Tetralogy of Fallot with Unilateral Absence of the Pulmonary Artery Open
Background: Tetralogy of Fallot (TOF) is the most common combined the deformity of unilateral absence of the pulmonary artery (UAPA). The treatment strategy of TOF combined with UAPA is still very controversial. In this study, we analyzed …
View article: The Outcomes of Total Anomalous Pulmonary Venous Connection in Neonates−10-Year Experience at a Single Center
The Outcomes of Total Anomalous Pulmonary Venous Connection in Neonates−10-Year Experience at a Single Center Open
Background: Recent developments in surgical techniques and hospital care have led to improved outcomes following repair of total anomalous pulmonary venous connection (TAPVC). However, surgical repair of neonatal TAPVC remains associated w…
View article: Inflammatory indicator levels in patients undergoing aortic valve replacement via median sternotomy with preoperative anxiety and postoperative complications: a prospective cohort study
Inflammatory indicator levels in patients undergoing aortic valve replacement via median sternotomy with preoperative anxiety and postoperative complications: a prospective cohort study Open
Objective This study was performed to evaluate the association of preoperative anxiety with inflammatory indicators and postoperative complications in patients undergoing scheduled aortic valve replacement surgery. Methods A prospective co…
View article: ImageCHD: A 3D Computed Tomography Image Dataset for Classification of Congenital Heart Disease
ImageCHD: A 3D Computed Tomography Image Dataset for Classification of Congenital Heart Disease Open
Congenital heart disease (CHD) is the most common type of birth defect, which occurs 1 in every 110 births in the United States. CHD usually comes with severe variations in heart structure and great artery connections that can be classifie…
View article: Effect of Family Socioeconomic Status on the Prognosis of Children with Epicardial Permanent Pacemaker: A 16-Year Experience at a Single Center
Effect of Family Socioeconomic Status on the Prognosis of Children with Epicardial Permanent Pacemaker: A 16-Year Experience at a Single Center Open
View article: Primary sutureless repair for infracardiac total anomalous pulmonary venous connection
Primary sutureless repair for infracardiac total anomalous pulmonary venous connection Open
OBJECTIVES This study aimed to review surgical experiences in patients with infracardiac total anomalous pulmonary venous connection (TAPVC). METHODS This retrospective study included 63 infants who underwent conventional repair (n = 27) a…
View article: Angiotensin II induces apoptosis in human induced pluripotent stem cell-derived cardiomyocytes
Angiotensin II induces apoptosis in human induced pluripotent stem cell-derived cardiomyocytes Open
Background The renin-angiotensin system (RAS) functions fundamentally to regulate the pathological process of cardiovascular diseases, such as heart failure and hypertension. As the major effector in RAS, angiotensin II activates angiotens…