Jun Lin
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View article: Virtual feasts and their impact: A pilot study on the influence of mukbang videos on eating behaviours, body image, and emotional wellbeing
Virtual feasts and their impact: A pilot study on the influence of mukbang videos on eating behaviours, body image, and emotional wellbeing Open
Mukbangs (i.e., 'eating broadcast') is a food-related social media trend often featuring a host consuming large amounts of food. This pilot study used the first pre-post experimental design to examine the immediate effects of watching a mu…
View article: Sequencing and bioinformatics analysis of exosome-derived miRNAs in mouse models of pancreatic injury induced by OSA
Sequencing and bioinformatics analysis of exosome-derived miRNAs in mouse models of pancreatic injury induced by OSA Open
Introduction The role of exosomal miRNAs involved in the pathogenesis and development of pancreatic injury caused by obstructive sleep apnea (OSA) remains unclear. Here, miRNA sequencing (miRNA-seq) was used to investigate the expression p…
View article: Systemic inflammatory indexes as predictors of 18-month mortality among cirrhotic patients receiving transjugular intrahepatic portosystemic shunt
Systemic inflammatory indexes as predictors of 18-month mortality among cirrhotic patients receiving transjugular intrahepatic portosystemic shunt Open
We identified systemic inflammatory indexes as significant prognostic biomarkers for disease-specific mortality post-TIPS. A predictive nomogram was constructed and validated with strong discriminative efficacy for risk stratification of d…
View article: Research on Constructing a prognosis prediction Model of Breast Cancer LncRNA Based on the TCGA Database
Research on Constructing a prognosis prediction Model of Breast Cancer LncRNA Based on the TCGA Database Open
Breast cancer remains a leading cause of cancer-related mortality in women, with challenges in prognosis prediction and therapeutic resistance. This study aimed to identify long non-coding RNAs (lncRNAs) associated with breast cancer progn…
View article: Electroacupuncture ameliorates cognitive dysfunction in T2DM rats by modulating astrocytic polarization and aberrant energy metabolism in the hippocampus via the Wnt/β-catenin pathway
Electroacupuncture ameliorates cognitive dysfunction in T2DM rats by modulating astrocytic polarization and aberrant energy metabolism in the hippocampus via the Wnt/β-catenin pathway Open
View article: Advancements in research leveraging phage display technology for gastric cancer diagnosis and treatment
Advancements in research leveraging phage display technology for gastric cancer diagnosis and treatment Open
Gastric cancer persists as a major global health challenge, ranking among the leading causes of cancer-related deaths worldwide. The high mortality rate primarily stems from difficulties in early detection, often resulting in late-stage di…
View article: Screening and Stability Analysis of Reference Genes in Pastor roseus
Screening and Stability Analysis of Reference Genes in Pastor roseus Open
Background/Objectives: Optimal reference genes for normalizing RT-qPCR data depend on the species, treatments, developmental stages, and other conditions. Pastor roseus is a long-distance migratory bird with potential applications in locus…
View article: 0961 Exploring mitochondrial dysfunction in miniaturized hair follicles: Insights into androgenetic alopecia
0961 Exploring mitochondrial dysfunction in miniaturized hair follicles: Insights into androgenetic alopecia Open
View article: Diversity of grasshoppers in different grassland types in the Western Tianshan Mountains of China and influencing factors
Diversity of grasshoppers in different grassland types in the Western Tianshan Mountains of China and influencing factors Open
Grasshoppers, as important primary consumers in grasslands, play a crucial role in maintaining the balance of grassland ecosystems. However, patterns of change in grasshopper diversity and their influencing factors vary with regions and gr…
View article: Multimodal AI diagnostic system for neuromyelitis optica based on ultrawide-field fundus photography
Multimodal AI diagnostic system for neuromyelitis optica based on ultrawide-field fundus photography Open
Purpose While deep learning (DL) has demonstrated significant utility in ocular diseases, no clinically validated algorithm currently exists for diagnosing neuromyelitis optica (NMO). This study aimed to develop a proof-of-concept multimod…
View article: Global Burden of Kidney Cancer Attributable to High Body Mass Index in Adults Aged 60 and Older from 1990 to 2021 and Projections to 2040: A Systematic Analysis for the Global Burden of Disease Study
Global Burden of Kidney Cancer Attributable to High Body Mass Index in Adults Aged 60 and Older from 1990 to 2021 and Projections to 2040: A Systematic Analysis for the Global Burden of Disease Study Open
This study shows a significant increase in kidney cancer burden due to high BMI in those aged ≥60 over 32 years, driven by population growth. Disparities across regions, genders, and age groups highlight the need for targeted prevention an…
View article: Research Progress on Cangfu Daotan Pills in the Treatment of Polycystic Ovary Syndrome
Research Progress on Cangfu Daotan Pills in the Treatment of Polycystic Ovary Syndrome Open
Polycystic ovary syndrome (PCOS) is a heterogeneous disease characterized clinically by high androgen levels, persistent anovulation, and polycystic ovarian changes, whose incidence has been on the rise, becoming a major factor in anovulat…
View article: Precision medicine in the prediction of metachronous liver metastasis in rectal cancer: Applications and challenges
Precision medicine in the prediction of metachronous liver metastasis in rectal cancer: Applications and challenges Open
Rectal cancer is a major global health concern, and metachronous liver metastasis (MLM) significantly worsens patient prognosis. Advances in imaging and machine learning have led to the development of radiomics models, particularly those u…
View article: Inhibitory effect on endometrial cancer: Collagen type XII α1 chain
Inhibitory effect on endometrial cancer: Collagen type XII α1 chain Open
Objective Endometrial cancer (EC) is one of the most common gynecological malignancies, and it poses a considerable threat to women’s lives. Therefore, searching for EC inhibitors and exploring the potential mechanism of action is particul…
View article: Risk factors for surgical site infection after general surgery in HIV-infected patients: a retrospective study
Risk factors for surgical site infection after general surgery in HIV-infected patients: a retrospective study Open
View article: Transcriptomic analysis of the gonads of <i>Locusta migratoria</i> (Orthoptera: Acrididae) following infection with <i>Paranosema locustae</i>
Transcriptomic analysis of the gonads of <i>Locusta migratoria</i> (Orthoptera: Acrididae) following infection with <i>Paranosema locustae</i> Open
Paranosema locustae is an environmentally friendly parasitic predator with promising applications in locust control. In this study, transcriptome sequencing was conducted on gonadal tissues of Locusta migratoria males and females infected …
View article: Multiple cell-death patterns predict the prognosis and drug sensitivity of melanoma patients
Multiple cell-death patterns predict the prognosis and drug sensitivity of melanoma patients Open
Background Melanoma, a malignant tumor of the skin, presents challenges in its treatment process involving modalities such as surgery, chemotherapy, and targeted therapy. However, there is a need for an ideal model to assess prognosis and …
View article: Causal relationship between systemic circulatory inflammatory regulators and intervertebral disc degeneration: A bidirectional 2-sample Mendelian randomization study
Causal relationship between systemic circulatory inflammatory regulators and intervertebral disc degeneration: A bidirectional 2-sample Mendelian randomization study Open
In the context of the development of intervertebral disc degeneration (IDD), inflammatory mediators play a pivotal role. Nevertheless, due to the influence of the inflammatory microenvironment, the causal relationship between specific infl…
View article: <i>Inonotus obliquus</i> polysaccharides prevent UVB-induced skin photodamage by modulating Sirt3-activated Foxo3a/PINK1-Parkin pathway: an <i>in vitro</i> and <i>in vivo</i> study
<i>Inonotus obliquus</i> polysaccharides prevent UVB-induced skin photodamage by modulating Sirt3-activated Foxo3a/PINK1-Parkin pathway: an <i>in vitro</i> and <i>in vivo</i> study Open
Inonotus obliquus, an edible and medicinal fungus, has proven to be beneficial for relieving body aging. Previous research has shown that I. obliquus polysaccharide (IOP) can effectively reduce oxidative stress and alleviate photoaging in …
View article: Causal Relationship Between Systemic Circulatory Inflammatory Regulators and Intervertebral Disc Degeneration: A Bidirectional Two-Sample Mendelian Randomization Study
Causal Relationship Between Systemic Circulatory Inflammatory Regulators and Intervertebral Disc Degeneration: A Bidirectional Two-Sample Mendelian Randomization Study Open
Background In the context of the development of Intervertebral Disc Degeneration (IDD), inflammatory mediators play a pivotal role. Nevertheless, due to the influence of the inflammatory microenvironment, the causal relationship between sp…
View article: P1025 Analysis of the Clinical Characteristics of Elderly-onset Crohn's Disease
P1025 Analysis of the Clinical Characteristics of Elderly-onset Crohn's Disease Open
Background The prevalence of Crohn's disease in the elderly is increasing today. The purpose of this study was to analyze the clinical characteristics of elderly-onset patients with Crohn's disease and compare with non-elderly-onset adult …
View article: Causal Relationship Between Systemic Circulatory Inflammatory Regulators and Intervertebral Disc Degeneration: A Bidirectional Two-Sample Mendelian Randomization Study
Causal Relationship Between Systemic Circulatory Inflammatory Regulators and Intervertebral Disc Degeneration: A Bidirectional Two-Sample Mendelian Randomization Study Open
Background In the context of the development of Intervertebral Disc Degeneration (IDD), inflammatory mediators play a pivotal role. Nevertheless, due to the influence of the inflammatory microenvironment, the causal relationship between sp…
View article: Correlation between the risk of lymph node metastasis and the expression of GBP1 in breast cancer patients
Correlation between the risk of lymph node metastasis and the expression of GBP1 in breast cancer patients Open
Objective: To explore the prognostic value and correlation between the risk of lymph node metastasis (LNM) and Guanylate-binding Protein 1 (GBP1) in breast cancer (BC) patients.
Methods: In this retrospective study, the clinical data of 1…
View article: The efficacy and safety of vonoprazan–amoxicillin dual therapy in eradicating Helicobacter pylori: a systematic review and meta-analysis
The efficacy and safety of vonoprazan–amoxicillin dual therapy in eradicating Helicobacter pylori: a systematic review and meta-analysis Open
View article: P-417 Biovular follicles are commonly found in prepubertal but not adult ovaries
P-417 Biovular follicles are commonly found in prepubertal but not adult ovaries Open
Study question Is the morphology of ovarian tissue from paediatric and adolescent girls similar to that from adults? Summary answer The presence of biovular follicles was more frequently observed in paediatric ovary than in the adult ovary…
View article: Effects of Different Ratios of BMP2 and VEGFA on the Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells
Effects of Different Ratios of BMP2 and VEGFA on the Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells Open
Bone morphogenetic protein-2 (BMP2) and vascular endothelial growth factor (VEGF) have been shown to synergistically promote bone formation via cell-based gene therapy. However, the optimal ratio of BMP2 to VEGFA required to enhance the be…
View article: Molecular and Clinical Characteristics of Carbapenem-Resistant Klebsiella pneumoniae Isolates at a Tertiary Hospital in Wuhan, China
Molecular and Clinical Characteristics of Carbapenem-Resistant Klebsiella pneumoniae Isolates at a Tertiary Hospital in Wuhan, China Open
Through whole genome sequencing (WGS), we found multiple drug-resistant genes and virulence factors, and there was obvious dominant microbiota. The source was mainly related to nosocomial infection. The ST11-KPC Klebsiella pneumoniae was t…
View article: MFG-E8 has guiding significance for the prognosis and treatment of sepsis
MFG-E8 has guiding significance for the prognosis and treatment of sepsis Open
View article: The third inactivated vaccine booster dramatically enhanced SARS‐CoV‐2 antibody responses and did not influence the profile of prothrombotic antibody
The third inactivated vaccine booster dramatically enhanced SARS‐CoV‐2 antibody responses and did not influence the profile of prothrombotic antibody Open
The purpose of this study is to investigate the production of both severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2)‐specific antibodies and autoantibodies in serum following the third booster vaccination of the inactivated COVI…
View article: Predicting Distant Metastasis in Young-Onset Colorectal Cancer After Surgery: A Retrospective Study
Predicting Distant Metastasis in Young-Onset Colorectal Cancer After Surgery: A Retrospective Study Open
Background Although overall colorectal cancer (CRC) cases have been declining worldwide, there has been an increase in the incidence of the CRC among individuals younger than 50 years old, which is associated with distant metastasis (DM) a…