Jiatao Liu
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View article: SLC25A39 regulates Hedgehog signaling to promote tumor progression and sorafenib resistance in hepatocellular carcinoma
SLC25A39 regulates Hedgehog signaling to promote tumor progression and sorafenib resistance in hepatocellular carcinoma Open
Sorafenib is the standard treatment for advanced hepatocellular carcinoma (HCC), yet resistance limits its efficacy. The Hedgehog (HH) signaling pathway contributes to drug resistance by maintaining HCC stem cell characteristics, but its r…
View article: Melatonin Prevents the Progression of MASLD via Inhibiting FFAs-Induced Ferroptosis through KEAP1/NRF2/HO-1 Pathway
Melatonin Prevents the Progression of MASLD via Inhibiting FFAs-Induced Ferroptosis through KEAP1/NRF2/HO-1 Pathway Open
The accumulation of free fatty acids (FFAs) in hepatocytes is a key characteristic of metabolic dysfunction-associated steatotic liver disease (MASLD), which leads to lipid peroxidation and ultimately results in ferroptosis. Currently, the…
View article: Screening for lipid metabolism-related genes and identifying the therapeutic potential of ACACA for ER stress-related progression in hepatocellular carcinoma
Screening for lipid metabolism-related genes and identifying the therapeutic potential of ACACA for ER stress-related progression in hepatocellular carcinoma Open
Aim: The reprogramming of lipid metabolism can markedly enhance the nutritional adaptability of tumor cells to the glucose-deficient and hypoxic tumor microenvironment, which holds profound significance for the development and metastasis o…
View article: Insulin resistance related indices are associated with the presence of Cardiorenal syndrome: insights from NHANES 2005-2020
Insulin resistance related indices are associated with the presence of Cardiorenal syndrome: insights from NHANES 2005-2020 Open
Background Cardiorenal syndrome (CRS) is a complex and severe clinical condition that is gaining increasing attention. Previous studies indicate that insulin resistance (IR) strongly correlates with cardiac diseases (e.g., coronary artery …
View article: Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis
Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis Open
View article: Endoplasmic reticulum stress-related super enhancer promotes epithelial-mesenchymal transformation in hepatocellular carcinoma through CREB5 mediated activation of TNC
Endoplasmic reticulum stress-related super enhancer promotes epithelial-mesenchymal transformation in hepatocellular carcinoma through CREB5 mediated activation of TNC Open
Super-enhancers (SEs) are associated with key genes that control cellular state and cell identity. Endoplasmic reticulum stress (ERS) regulates epithelial-mesenchymal transformation (EMT). However, whether SEs are involved in ERS-related a…
View article: Dynamic Momentum Strategies: Return Dispersion and Predictability
Dynamic Momentum Strategies: Return Dispersion and Predictability Open
View article: By integrating single-cell RNA sequencing and bulk RNA sequencing, plasma cells signature and tertiary lymphoid structures were verified to contribute to outcome in lung adenocarcinoma
By integrating single-cell RNA sequencing and bulk RNA sequencing, plasma cells signature and tertiary lymphoid structures were verified to contribute to outcome in lung adenocarcinoma Open
Plasma cells and TLS can effectively predict the prognosis of LUAD. In the tumor microenvironment (TME) of advanced tumors, plasma cells might be in a state of functional exhaustion. Comprehensive characterization of TLS and corresponding …
View article: Preparation and property study of sawdust-modified cement mortar
Preparation and property study of sawdust-modified cement mortar Open
Sawdust, a solid waste generated during stone processing, poses a serious threat to the environment with its untreated accumulation. This paper first analyzes the chemical composition and physical properties of sawdust, and discusses its m…
View article: The Forces Associated with Bolus Injection and Continuous Infusion Techniques during Ultrasound-Targeted Nerve Contact: An Ex Vivo Study
The Forces Associated with Bolus Injection and Continuous Infusion Techniques during Ultrasound-Targeted Nerve Contact: An Ex Vivo Study Open
Ultrasound-guided regional anaesthesia with real-time visualization of anatomical structures and needle trajectory has become the standard method for accurately achieving nerve block procedures. Nevertheless, ultrasound is particularly lim…
View article: Nanoparticles alleviate non-alcoholic steatohepatitis via ER stress sensor-mediated intestinal barrier damage and gut dysbiosis
Nanoparticles alleviate non-alcoholic steatohepatitis via ER stress sensor-mediated intestinal barrier damage and gut dysbiosis Open
Introduction The gut microbiota plays an important role in the development of non-alcoholic steatohepatitis (NASH), but the underlying mechanism is unclear. It has been found that the transcription factor XBP1s plays an important role in r…
View article: Navigating Digital Frontiers: The Impact of China's Cybersecurity Law on Corporate Digital Innovation
Navigating Digital Frontiers: The Impact of China's Cybersecurity Law on Corporate Digital Innovation Open
View article: Lmnet: A Learnable Multi-Scale Cost Volume for Stereo Matching
Lmnet: A Learnable Multi-Scale Cost Volume for Stereo Matching Open
View article: The Impact of Data Privacy Misconduct: Evidence from Firms' Malpractice via APPs 
The Impact of Data Privacy Misconduct: Evidence from Firms' Malpractice via APPs Open
View article: siRNA-loaded folic acid-modified TPGS alleviate MASH <i>via</i> targeting ER stress sensor XBP1 and reprogramming macrophages
siRNA-loaded folic acid-modified TPGS alleviate MASH <i>via</i> targeting ER stress sensor XBP1 and reprogramming macrophages Open
Macrophages show high plasticity and play a vital role in the progression of metabolic dysfunction-associated steatohepatitis (MASH). X-box binding protein 1 (XBP1), a key sensor of the unfolded protein response, can modulate macrophage-me…
View article: GTMNet: a vision transformer with guided transmission map for single remote sensing image dehazing
GTMNet: a vision transformer with guided transmission map for single remote sensing image dehazing Open
Existing dehazing algorithms are not effective for remote sensing images (RSIs) with dense haze, and dehazed results are prone to over-enhancement, color distortion, and artifacts. To tackle these problems, we propose a model GTMNet based …
View article: miR-143-null Is against Diet-Induced Obesity by Promoting BAT Thermogenesis and Inhibiting WAT Adipogenesis
miR-143-null Is against Diet-Induced Obesity by Promoting BAT Thermogenesis and Inhibiting WAT Adipogenesis Open
Excessive energy intake is the main cause of obesity, and stimulation of brown adipose tissue (BAT) thermogenesis has emerged as an attractive tool for anti-obesity. Although miR-143 has been reported to promote white adipocyte differentia…
View article: High quality monocular depth estimation with parallel decoder
High quality monocular depth estimation with parallel decoder Open
View article: ARHGEF2/EDN1 pathway participates in ER stress-related drug resistance of hepatocellular carcinoma by promoting angiogenesis and malignant proliferation
ARHGEF2/EDN1 pathway participates in ER stress-related drug resistance of hepatocellular carcinoma by promoting angiogenesis and malignant proliferation Open
Endoplasmic reticulum (ER) stress is widely involved in the drug resistance of hepatocellular carcinoma (HCC), but the mechanism of ER stress-induced drug resistance involves multiple signaling pathways that cannot be fully explained. Expl…
View article: High expressions of PKM2 protein cause decreased apoptosis rate and radiosensitivity in hepatocellular carcinoma cells
High expressions of PKM2 protein cause decreased apoptosis rate and radiosensitivity in hepatocellular carcinoma cells Open
Background: The expression of PKM2 and radiation sensitivity of three HCC cell lines were tested to observe the effects of PKM2 on apoptosis and radiation sensitivity of HCC cells. Methods: PKM2 proteins in the three cell lines were tested…
View article: Cost–Effectiveness Analysis of Dapagliflozin Plus Standard Treatment for Patients With Type 2 Diabetes and High Risk of Cardiovascular Disease in China
Cost–Effectiveness Analysis of Dapagliflozin Plus Standard Treatment for Patients With Type 2 Diabetes and High Risk of Cardiovascular Disease in China Open
Purpose To evaluate the long-term cost-effectiveness of dapagliflozin, in addition to standard treatment, for the treatment of adult patients with type 2 diabetes (T2DM) at high cardiovascular risk from the Chinese healthcare system perspe…
View article: Increased Serum Trimethylamine N-Oxide Level in Type 2 Diabetic Patients with Mild Cognitive Impairment
Increased Serum Trimethylamine N-Oxide Level in Type 2 Diabetic Patients with Mild Cognitive Impairment Open
Our study showed that T2DM patients with MCI have elevated serum TMAO levels.
View article: Cybercrime and the Cross-Section of Equity Returns
Cybercrime and the Cross-Section of Equity Returns Open
View article: Spillovers from the oil market to other financial markets in the frequency domain: How important is quantitative easing?
Spillovers from the oil market to other financial markets in the frequency domain: How important is quantitative easing? Open
View article: Endoplasmic reticulum stress promotes sorafenib resistance via miR-188-5p/hnRNPA2B1-mediated upregulation of PKM2 in hepatocellular carcinoma
Endoplasmic reticulum stress promotes sorafenib resistance via miR-188-5p/hnRNPA2B1-mediated upregulation of PKM2 in hepatocellular carcinoma Open
View article: A zinc finger family protein, ZNF263, promotes hepatocellular carcinoma resistance to apoptosis via activation of ER stress-dependent autophagy
A zinc finger family protein, ZNF263, promotes hepatocellular carcinoma resistance to apoptosis via activation of ER stress-dependent autophagy Open
View article: FGL1 regulates acquired resistance to Gefitinib by inhibiting apoptosis in non-small cell lung cancer
FGL1 regulates acquired resistance to Gefitinib by inhibiting apoptosis in non-small cell lung cancer Open
Background This study investigated the role of fibrinogen-like protein 1 (FGL1) in regulating gefitinib resistance of PC9/GR non-small cell lung cancer (NSCLC). Methods The effect of different concentrations of gefitinib on cell proliferat…
View article: FGL1 Regulates Acquired Resistance to Gefitinib by Inhibiting Apoptosis in Non-small Cell Lung Cancer
FGL1 Regulates Acquired Resistance to Gefitinib by Inhibiting Apoptosis in Non-small Cell Lung Cancer Open
Background: This study investigated the role of fibrinogen-like protein 1 (FGL1) in regulating gefitinib resistance of PC9/GR non-small cell lung cancer (NSCLC). Methods : The effect of different concentrations of gefitinib on cell prolife…
View article: Overexpression of Rictor protein and Rictor-H. pylori interaction has impact on tumor progression and prognosis in patients with gastric cancer
Overexpression of Rictor protein and Rictor-H. pylori interaction has impact on tumor progression and prognosis in patients with gastric cancer Open
Our results demonstrate that Rictor, acting as an oncogene, might be a potential prognostic biomarker and therapeutic target in GC. We suggest that Rictor expression and H. pylori status may be a prognostic marker in gastric cancer.
View article: FGL1 Regulates Acquired Resistance to Gefitinib by Inhibiting Apoptosis in Non-small Cell Lung Cancer
FGL1 Regulates Acquired Resistance to Gefitinib by Inhibiting Apoptosis in Non-small Cell Lung Cancer Open
Background: This study investigated the role of fibrinogen-like protein 1 (FGL1) in regulating gefitinib resistance of PC9/GR non-small cell lung cancer (NSCLC). Methods : The effect of different concentrations of gefitinib on cell prolife…