Jiaxin Fan
YOU?
Author Swipe
View article: Exosomal circ_0093708 as a potential ferroptosis biomarker in cerebral ischemia–reperfusion injury
Exosomal circ_0093708 as a potential ferroptosis biomarker in cerebral ischemia–reperfusion injury Open
Background Ferroptosis plays a critical role in neuronal injury following cerebral infarction. However, effective therapeutic strategies targeting ferroptosis after cerebral ischemia–reperfusion injury (CI/RI) remain limited. Exosome-based…
View article: Explainable machine learning-driven models for predicting Parkinson’s disease and its prognosis: obesity patterns associations and models development using NHANES 1999–2018 data
Explainable machine learning-driven models for predicting Parkinson’s disease and its prognosis: obesity patterns associations and models development using NHANES 1999–2018 data Open
View article: NMB promotes the progression of colorectal cancer by regulating the NF-κB/P65 signaling pathway
NMB promotes the progression of colorectal cancer by regulating the NF-κB/P65 signaling pathway Open
Background Colorectal carcinoma (CRC) ranks as the fourth most prevalent malignancy globally. Neuromedin B (NMB) and its corresponding receptor have been implicated in the pathogenesis of multiple neoplastic conditions. Nevertheless, the s…
View article: Association between life's essential 8 and Parkinson's disease: a case–control study
Association between life's essential 8 and Parkinson's disease: a case–control study Open
Objectives Life's essential 8 (LE8) is an emerging approach for accessing and quantifying cardiovascular health (CVH), but the effect on Parkinson's disease (PD) is still unclear. This study aimed to elucidate the association between LE8 m…
View article: Calcium-sensing receptors promoted Homer1 expression and osteogenic differentiation in bone marrow mesenchymal stem cells
Calcium-sensing receptors promoted Homer1 expression and osteogenic differentiation in bone marrow mesenchymal stem cells Open
Homer1 interacts with calcium-sensing receptors (CaSRs) in osteoblasts (OBs), with both CaSR and Homer1 playing essential roles in AKT phosphorylation. This study investigated the impact of CaSR on Homer1 expression during the differentiat…
View article: Dimensional Engineering of Mn(Ii) Complexes Via Single-Crystal to Single-Crystal Transformation for Efficient Photoelectrocatalytic Water Oxidation
Dimensional Engineering of Mn(Ii) Complexes Via Single-Crystal to Single-Crystal Transformation for Efficient Photoelectrocatalytic Water Oxidation Open
View article: Dimensional Engineering of Mn(Ii) Complexes Via Single-Crystal to Single-Crystal Transformation for Efficient Photoelectrocatalytic Water Oxidation
Dimensional Engineering of Mn(Ii) Complexes Via Single-Crystal to Single-Crystal Transformation for Efficient Photoelectrocatalytic Water Oxidation Open
View article: Catestatin Attenuates Cerebral Ischemia/Reperfusion Injury and Suppresses Endoplasmic Reticulum Stress
Catestatin Attenuates Cerebral Ischemia/Reperfusion Injury and Suppresses Endoplasmic Reticulum Stress Open
View article: Pyridazine-Based Hydrogen-Bond Engineered Lanthanide Hofs for Dual-Function Ratiometric Sensing and High Proton Conduction
Pyridazine-Based Hydrogen-Bond Engineered Lanthanide Hofs for Dual-Function Ratiometric Sensing and High Proton Conduction Open
View article: The effects of coagulation factors on the risk of Alzheimer’s disease: A Mendelian randomization study
The effects of coagulation factors on the risk of Alzheimer’s disease: A Mendelian randomization study Open
Background Observational studies indicate a complex relationship between coagulation factors and Alzheimer's disease (AD). However, the current findings are inconsistent, and it remains uncertain whether a causal relationship exists. Objec…
View article: A Data-Enhanced Deep Learning Approach for Emergency Domain Question Intention Recognition in Urban Rail Transit
A Data-Enhanced Deep Learning Approach for Emergency Domain Question Intention Recognition in Urban Rail Transit Open
View article: Spermine Alleviates Hippocampal Neuronal Aging by Targeting Tlr4 Receptors to Regulate Erk1/Mek5 Expression
Spermine Alleviates Hippocampal Neuronal Aging by Targeting Tlr4 Receptors to Regulate Erk1/Mek5 Expression Open
View article: Metal-Center Engineering in Mn(Ii)/Zn(Ii) Hydrogen-Bonded Frameworks for Enhanced Photoelectrocatalytic Water Oxidation
Metal-Center Engineering in Mn(Ii)/Zn(Ii) Hydrogen-Bonded Frameworks for Enhanced Photoelectrocatalytic Water Oxidation Open
View article: Multi-Stage Deep Learning-Enabled Flexible Physiological Signal Fusion Modeling for Non-Destructive Stress Detection of Live Fish
Multi-Stage Deep Learning-Enabled Flexible Physiological Signal Fusion Modeling for Non-Destructive Stress Detection of Live Fish Open
View article: Ph/Solvent Induced Single-Crystal-To-Single-Crystal Transformation from 0d Mn(Ii) Monomer to 1d Chain and 2d Layer for Boosting Photoelectrocatalytic Water-Splitting
Ph/Solvent Induced Single-Crystal-To-Single-Crystal Transformation from 0d Mn(Ii) Monomer to 1d Chain and 2d Layer for Boosting Photoelectrocatalytic Water-Splitting Open
View article: Metformin mitigates osteoarthritis progression by modulating the PI3K/AKT/mTOR signaling pathway and enhancing chondrocyte autophagy
Metformin mitigates osteoarthritis progression by modulating the PI3K/AKT/mTOR signaling pathway and enhancing chondrocyte autophagy Open
Osteoarthritis (OA) is a chronic degenerative disease characterized by overall joint tissue damage. Metformin (Met) has been shown to inhibit inflammatory reactions, though its potential protective mechanism on cartilage remains unclear. T…
View article: Two-Stream Networks for Contrastive Learning in Hyperspectral Image Classification
Two-Stream Networks for Contrastive Learning in Hyperspectral Image Classification Open
In the domain of hyperspectral image (HSI) classification, the majority of deep learning methods have necessitated a substantial number of manually annotated samples to achieve outstanding results. However, the process of annotating HSI is…
View article: Magnetocardiography-based coronary artery disease severity assessment and localization using spatiotemporal features
Magnetocardiography-based coronary artery disease severity assessment and localization using spatiotemporal features Open
Objective. This study aimed to develop an automatic and accurate method for severity assessment and localization of coronary artery disease (CAD) based on an optically pumped magnetometer magnetocardiography (MCG) system. Approach. We prop…
View article: Elevated systemic immune-inflammation index is associated with a high risk of stroke in patients with internal carotid artery stenosis
Elevated systemic immune-inflammation index is associated with a high risk of stroke in patients with internal carotid artery stenosis Open
Background: Systemic immune-inflammation index (SII) is currently considered as a potential new inflammatory marker, but its association with internal carotid artery (ICA) stenosis has been poorly studied. Therefore, the purpose of this st…
View article: Classification of hyperspectral image by preprocessing method based relation network
Classification of hyperspectral image by preprocessing method based relation network Open
Hyperspectral image classification involves assigning a land cover class to each pixel of a hyperspectral image (HSI). Recently, several classification methods based on deep learning with spatial information from HSI have been proposed. Th…
View article: Boosting Chinese ASR Error Correction with Dynamic Error Scaling Mechanism
Boosting Chinese ASR Error Correction with Dynamic Error Scaling Mechanism Open
Chinese Automatic Speech Recognition (ASR) error correction presents significant challenges due to the Chinese language's unique features, including a large character set and borderless, morpheme-based structure. Current mainstream models …
View article: A nonclassically secreted effector of <i>Magnaporthe oryzae</i> targets host nuclei and plays important roles in fungal growth and plant infection
A nonclassically secreted effector of <i>Magnaporthe oryzae</i> targets host nuclei and plays important roles in fungal growth and plant infection Open
Rice blast caused by Magnaporthe oryzae is one of the most destructive diseases and poses a growing threat to food security worldwide. Like many other filamentous pathogens, rice blast fungus releases multiple types of effector proteins to…
View article: Hierarchical contribution of individual lifestyle factors and their interactions on adenomatous and serrated polyp risk
Hierarchical contribution of individual lifestyle factors and their interactions on adenomatous and serrated polyp risk Open
View article: A crucial exosome-related gene pair (AAMP and ABAT) is associated with inflammatory cells in intervertebral disc degeneration
A crucial exosome-related gene pair (AAMP and ABAT) is associated with inflammatory cells in intervertebral disc degeneration Open
Identification of exosome-related genes (ERGs) and competing endogenous RNAs (ceRNAs) associated with intervertebral disc degeneration (IDD) may improve its diagnosis and reveal its underlying mechanisms. We downloaded 49 samples from Gene…
View article: Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysis
Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysis Open
Background This study aimed to evaluate the diagnostic accuracy of magnetocardiograph, a relatively new noninvasive device, in patients with myocardial infarction (MI). Methods To identify studies assessing the diagnostic accuracy of magne…
View article: Nighttime sleep duration and variability in children with obstructive sleep apnea syndrome: Sociodemographic disparities and neurobehavioral outcomes
Nighttime sleep duration and variability in children with obstructive sleep apnea syndrome: Sociodemographic disparities and neurobehavioral outcomes Open
View article: Citronellal Attenuates Oxidative Stress–Induced Mitochondrial Damage through TRPM2/NHE1 Pathway and Effectively Inhibits Endothelial Dysfunction in Type 2 Diabetes Mellitus
Citronellal Attenuates Oxidative Stress–Induced Mitochondrial Damage through TRPM2/NHE1 Pathway and Effectively Inhibits Endothelial Dysfunction in Type 2 Diabetes Mellitus Open
In type 2 diabetes mellitus (T2DM), oxidative stress induces endothelial dysfunction (ED), which is closely related to the formation of atherosclerosis. However, there are few effective drugs to prevent and cure it. Citronellal (CT) is an …
View article: The relationship between serum cystatin C levels and Hughes motor scale in Guillain-Barré syndrome
The relationship between serum cystatin C levels and Hughes motor scale in Guillain-Barré syndrome Open
OBJECTIVES: To study the clinical features of Guillain–Barré syndrome (GBS) and the relationship between serum cystatin C (cysC) levels and Hughes motor scale (HMS) in GBS. METHODS: One hundred and one GBS patients between January 2017 and…
View article: PVT-COV19D: Pyramid Vision Transformer for COVID-19 Diagnosis
PVT-COV19D: Pyramid Vision Transformer for COVID-19 Diagnosis Open
With the outbreak of COVID-19, a large number of relevant studies have emerged in recent years. We propose an automatic COVID-19 diagnosis framework based on lung CT scan images, the PVT-COV19D. In order to accommodate the different dimens…
View article: Identification and Validation of a Pyroptosis-Related Prognostic Model for Gastric Cancer
Identification and Validation of a Pyroptosis-Related Prognostic Model for Gastric Cancer Open
Pyroptosis is an inflammatory form of programmed cell death triggered by caspase-1/4/5/11 that plays an important role in the occurrence and development of gastric cancer (GC). We investigated the prognostic value of pyroptosis-related gen…