Jiayan Fang
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View article: SR‐717, a Non‐Nucleotide STING Agonist, Displayed Anti‐Radiation Activity in a IL‐6 Dependent Manner
SR‐717, a Non‐Nucleotide STING Agonist, Displayed Anti‐Radiation Activity in a IL‐6 Dependent Manner Open
Ionizing radiation (IR) induced damages are common complications of radiotherapy for tumors, severely limiting the intensity and therapeutic efficacy of the radiotherapy program. Emerging data indicated that the cGAS‐STING pathway has para…
View article: Visual Outcomes and IOL Stability After Panoptix Trifocal Intraocular Lens Implantation in Eyes With High Myopia
Visual Outcomes and IOL Stability After Panoptix Trifocal Intraocular Lens Implantation in Eyes With High Myopia Open
Purpose To observe and explore the correlation between visual outcomes and intraocular lens (IOL) stability after tri-focal IOL implantation in eyes with high myopia. Methods Patients with highly myopic cataract (axial length > 26 mm) were…
View article: A Fuzzy Reinforcement LSTM-based Long-term Prediction Model for Fault Conditions in Nuclear Power Plants
A Fuzzy Reinforcement LSTM-based Long-term Prediction Model for Fault Conditions in Nuclear Power Plants Open
Early fault detection and timely maintenance scheduling can significantly mitigate operational risks in NPPs and enhance the reliability of operator decision-making. Therefore, it is necessary to develop an efficient Prognostics and Health…
View article: Research on an intelligent fault diagnosis method for nuclear power plants based on ETCN-SSA combined algorithm
Research on an intelligent fault diagnosis method for nuclear power plants based on ETCN-SSA combined algorithm Open
Utilizing fault diagnosis methods is crucial for nuclear power professionals to achieve efficient and accurate fault diagnosis for nuclear power plants (NPPs). The performance of traditional methods is limited by their dependence on comple…
View article: Myricetin ameliorates airway inflammation and remodeling in asthma by activating Sirt1 to regulate the JNK/Smad3 pathway
Myricetin ameliorates airway inflammation and remodeling in asthma by activating Sirt1 to regulate the JNK/Smad3 pathway Open
Myricetin ameliorates airway inflammation and remodeling in asthma by activating Sirt1 to regulate the JNK/Smad3 pathway.
View article: Ferroptosis-related genes DUOX1 and HSD17B11 affect tumor microenvironment and predict overall survival of lung adenocarcinoma patients
Ferroptosis-related genes DUOX1 and HSD17B11 affect tumor microenvironment and predict overall survival of lung adenocarcinoma patients Open
Background: Recent studies have found that ferroptosis-related genes (FRGs) have broad applications in tumor therapy. However, the predictive potential of these genes in lung adenocarcinoma (LUAD) remains to be fully characterized. We aime…
View article: Prognostic model for unresectable hepatocellular carcinoma treated with dual PD-1 and angiogenesis blockade therapy
Prognostic model for unresectable hepatocellular carcinoma treated with dual PD-1 and angiogenesis blockade therapy Open
Background and aims Dual programmed death 1 (PD-1) and angiogenesis blockade therapy is a frontline treatment for hepatocellular carcinoma (HCC). An accepted model for survival prediction and risk stratification in individual patients rece…
View article: Emetine dihydrochloride alleviated radiation‐induced lung injury through inhibiting EMT
Emetine dihydrochloride alleviated radiation‐induced lung injury through inhibiting EMT Open
Radiation‐induced lung injury (RILI), divided into early radiation pneumonia (RP) and late radiation‐induced pulmonary fibrosis (RIPF), is a common serious disease after clinical chest radiotherapy or nuclear accident, which seriously thre…
View article: Evaluation of optic nerve head vessels density changes after phacoemulsification cataract surgery using optical coherence tomography angiography
Evaluation of optic nerve head vessels density changes after phacoemulsification cataract surgery using optical coherence tomography angiography Open
AIM: To evaluate optic nerve head (ONH) vessel density (VD) changes after cataract surgery using optical coherence tomography angiography (OCTA). METHODS: This was a prospective observational study. Thirty-four eyes with mild/moderate cata…
View article: PBK/TOPK promotes chemoresistance to oxaliplatin in hepatocellular carcinoma cells by regulating PTEN
PBK/TOPK promotes chemoresistance to oxaliplatin in hepatocellular carcinoma cells by regulating PTEN Open
Oxaliplatin (OXA) resistance limits the efficiency of treatment for hepatocellular carcinoma (HCC). Studies have shown that the PDZ-binding kinase (PBK) plays important roles in tumors. However, the role of PBK in HCC is still a problem. I…
View article: A Generic Block-Level Error Confinement Technique for Memory Based on Principal Component Analysis
A Generic Block-Level Error Confinement Technique for Memory Based on Principal Component Analysis Open
Nanoscale CMOS technology has encountered severe reliability issues especially in on-chip memory. Conventional word-level error resilience techniques such as Error Correcting Codes (ECC) suffer from high physical overhead and inability to …