Jiaying Mo
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View article: The Leucine-mTOR-Autophagy Axis in Granulosa Cells Mediates Circadian Disruption-Induced Anovulation
The Leucine-mTOR-Autophagy Axis in Granulosa Cells Mediates Circadian Disruption-Induced Anovulation Open
Background: Ovulation disorders represent the most common cause of infertility in women. Previous studies have reported that continuous light exposure can induce anovulation. However, the underlying mechanisms remain unclear. Methods: We a…
View article: Gestational diabetes induces autistic-like behaviors in offspring by disrupting the GABAergic system
Gestational diabetes induces autistic-like behaviors in offspring by disrupting the GABAergic system Open
Background Increasing evidence have shown that gestational diabetes mellitus (GDM) is associated with the risk of autism in offspring. However, the underlying mechanisms have not yet been fully elucidated. Methods A mouse model of gestatio…
View article: Intrauterine hyperglycemia during late gestation caused mitochondrial dysfunction in skeletal muscle of male offspring through CREB/PGC1A signaling
Intrauterine hyperglycemia during late gestation caused mitochondrial dysfunction in skeletal muscle of male offspring through CREB/PGC1A signaling Open
Background: Maternal diabetes mellitus can influence the development of offspring. Gestational diabetes mellitus (GDM) creates short-term intrauterine hyperglycemic environment for offspring, leading to insulin resistance in skeletal muscl…
View article: Glymphatic system impairment contributes to the formation of brain edema after ischemic stroke
Glymphatic system impairment contributes to the formation of brain edema after ischemic stroke Open
The blood-brain barrier (BBB) damage has traditionally been considered to determine the occurrence and development of post-stroke brain edema, a devastating and life-threatening complication. However, no treatment strategy targeting BBB da…
View article: Bisphenols and Leydig Cell Development and Function
Bisphenols and Leydig Cell Development and Function Open
Bisphenol A (BPA) is a ubiquitous environmental pollutant, mainly from the production and use of plastics and the degradation of wastes related to industrial plastics. Evidence from laboratory animal and human studies supports the view tha…
View article: Fibroblast growth factor homologous factor 1 stimulates Leydig cell regeneration from stem cells in male rats
Fibroblast growth factor homologous factor 1 stimulates Leydig cell regeneration from stem cells in male rats Open
Fibroblast growth factor homologous factor 1 (FHF1) is an intracellular protein that does not bind to cell surface fibroblast growth factor receptor. Here, we report that FHF1 is abundantly present in Leydig cells with up‐regulation during…