Jing Du
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View article: Prolonged Crowding Initiates Tumor Invasion with Mechanomemory by Pressure-Sensation of Membrane Domains
Prolonged Crowding Initiates Tumor Invasion with Mechanomemory by Pressure-Sensation of Membrane Domains Open
During the progression from epithelial neoplasms to invasive carcinoma, cells are subjected to prolonged confinement. However, the response of cancer cells to such mild yet sustained compressive pressure during the initial stages of tumor …
View article: Case report: Preimplantation genetic testing for X-linked alport syndrome caused by variation in the COL4A5 gene
Case report: Preimplantation genetic testing for X-linked alport syndrome caused by variation in the COL4A5 gene Open
X-Linked Alport Syndrome (XLAS) is an X-linked, dominant, hereditary nephropathy mainly caused by mutations in the COL4A5 gene, found on chromosome Xq22. In this study, we reported a pedigree with XLAS caused by a COL4A5 mutation. This fam…
View article: P-708 Establishment of linkage phase, using Oxford Nanopore Technologies, for Preimplantation Genetic Testing of Coffin-Lowry syndrome with a de novo RPS6KA3 mutation
P-708 Establishment of linkage phase, using Oxford Nanopore Technologies, for Preimplantation Genetic Testing of Coffin-Lowry syndrome with a de novo RPS6KA3 mutation Open
Study question There was a challenge to establishing haplotype for PGT in the family with de novo mutation because of the lack of information from affected members. Summary answer The ONT platform combined with MARSALA method can be used t…
View article: The Impact of Floating Raft Aquaculture on the Hydrodynamic Environment of an Open Sea Area in Liaoning Province, China
The Impact of Floating Raft Aquaculture on the Hydrodynamic Environment of an Open Sea Area in Liaoning Province, China Open
The sea area of Changhai County in Dalian City is a typical floating raft aquaculture area, located in Liaoning Province, China, where a key issue in determining the scale and spatial layout of the floating raft aquaculture is the assessme…
View article: Integrated proteomics and metabolomics reveal the variations in the physiological state of spotted seal (Phoca largha) pups following artificial rescue
Integrated proteomics and metabolomics reveal the variations in the physiological state of spotted seal (Phoca largha) pups following artificial rescue Open
Spotted seals (Phoca largha) are a critically endangered pinniped in China. Artificial rescue of newborn pups is a conventional method to enhance their survival and maintain the population. However, little is known about the variations in …
View article: Preliminary construction of evaluation index system and method of regional suitability of straw storage and transportation mode
Preliminary construction of evaluation index system and method of regional suitability of straw storage and transportation mode Open
The industrial utilization of straw from the field is an important way to achieve its comprehensive utilization. Construction of an efficient collection system is the premise and foundation for the efficient utilization of straw resources.…
View article: Age‐associated variation in the gut microbiota of chinstrap penguins (<i>Pygoscelis antarctica</i>) reveals differences in food metabolism
Age‐associated variation in the gut microbiota of chinstrap penguins (<i>Pygoscelis antarctica</i>) reveals differences in food metabolism Open
Age is known to affect the gut microbiota in various animals; however, this relationship is poorly understood in seabirds. We investigated the temporal succession of gut microbiota in captive chinstrap penguins of different ages using high…
View article: Proteomics reveals the preliminary physiological states of the spotted seal (Phoca largha) pups
Proteomics reveals the preliminary physiological states of the spotted seal (Phoca largha) pups Open
Spotted seal ( Phoca largha ) is a critically endangered pinniped in China and South Korea. The conventional method to protect and maintain the P. largha population is to keep them captive in artificially controlled environments. However, …
View article: Distribution of microbiota across different intestinal tract segments of a stranded dwarf minke whale, <i>Balaenoptera acutorostrata</i>
Distribution of microbiota across different intestinal tract segments of a stranded dwarf minke whale, <i>Balaenoptera acutorostrata</i> Open
Marine mammals are an important part of ocean ecosystems, of which, whales play a vital role in the marine food chain. In this study, the mucosa and contents from different intestinal tract segments (ITSs) of a stranded dwarf minke whale (…
View article: Bibliometric Profile of Global Microplastics Research from 2004 to 2019
Bibliometric Profile of Global Microplastics Research from 2004 to 2019 Open
Microplastics (MPs) have generated worldwide attention due to their global distribution in the environment, and their potential harmful effects on human and animal health. To analyze MPs-related scientific publications from a global point …
View article: Gut microbiota variations in a rescued spotted seal Phoca largha pup
Gut microbiota variations in a rescued spotted seal Phoca largha pup Open
Rescuing seal pups is an important conservation action for spotted seals Phoca largha . Gut microbiota are directly associated with host health and diet metabolism. Therefore, knowledge gained from gut microbiota variations of spotted seal…
View article: Concerted Efforts Are Needed to Control and Mitigate Antibiotic Pollution in Coastal Waters of China
Concerted Efforts Are Needed to Control and Mitigate Antibiotic Pollution in Coastal Waters of China Open
Antibiotics have been applied for decades and antibiotic pollution is of great concern due to the risk for promoting resistant genes. Human activities such as mariculture and land-based discharge can lead to the antibiotic pollution in coa…
View article: Identification of the complete mitochondrial genome of the king penguin<i>Aptenodytes patagonicus</i>(Sphenisciformes: Spheniscidae: Aptenodytes)
Identification of the complete mitochondrial genome of the king penguin<i>Aptenodytes patagonicus</i>(Sphenisciformes: Spheniscidae: Aptenodytes) Open
The complete mitochondrial genome of the king penguin Aptenodytes patagonicus was firstly determined. The mitogenome is 17,477 bp in length and contains 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, 2 ribosomal RNA (rRNA) g…
View article: Complete mitochondrial genome of South American sea lion <i>Otaria byronia</i> (Carnivora: Otariidae)
Complete mitochondrial genome of South American sea lion <i>Otaria byronia</i> (Carnivora: Otariidae) Open
The complete mitochondrial genome of Otaria byronia was sequenced for the first time. The mitogenome is 16,640 bp long and encodes 13 protein-coding genes (PCGs), 22 tRNA genes, two rRNA genes, one origin of light strand replication (OL), …
View article: Role of ginsenosides in reactive oxygen species-mediated anticancer therapy
Role of ginsenosides in reactive oxygen species-mediated anticancer therapy Open
Cancer is still a global public health problem, which is the leading cause of death in most countries. Ginseng has been used for centuries all over the world as a panacea that promotes longevity. As the king of herb plants, ginseng holds g…
View article: Evaluation of pilotage dispatching operation for Dalian Port in China based on FCE–AHP method
Evaluation of pilotage dispatching operation for Dalian Port in China based on FCE–AHP method Open
Objective: The continuous expansion of the port with the critical shortage for maritime pilots and vessels calls for an effective pilotage dispatching operation, which can ensure the timely delivery of information and rational utilization …
View article: Functions of Circular RNAs in the Research of Reproductive and Developmental Medicine
Functions of Circular RNAs in the Research of Reproductive and Developmental Medicine Open
Circular RNAs (circRNAs) represent a mysterious class of noncoding RNAs that are generated by the circularization of exons or introns and characterized as being highly stable and abundant. Although circRNAs have been studied for several de…
View article: Serious Game for Human Environmental Consciousness Education in Residents Daily Life
Serious Game for Human Environmental Consciousness Education in Residents Daily Life Open
It has been challenging to find ways to educate people to have better environmental consciousness. In some cases, people do not know what the right behaviors are to protect the environment. Game engine has been used in the AEC industry for…