Jichun Wang
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View article: An Efficient Deep Learning Framework for Revealing the Evolution of Characterization Methods in Nanoscience
An Efficient Deep Learning Framework for Revealing the Evolution of Characterization Methods in Nanoscience Open
View article: A comprehensive evaluation of a novel targeted-sequencing workflow for Mycobacterium species identification and anti-tuberculosis drug-resistance detection
A comprehensive evaluation of a novel targeted-sequencing workflow for Mycobacterium species identification and anti-tuberculosis drug-resistance detection Open
Background Although several World Health Organization–endorsed targeted next-generation sequencing (tNGS) assays exist for tuberculosis (TB) drug-resistance detection, their target selection and diagnostic accuracy vary widely. In this stu…
View article: Correction: Abdulrahim et al. Evaluation of Tissue Tropism and Horizontal Transmission of a Duck Enteritis Virus Vectored Vaccine in One-Day-Old Chicken. Viruses 2024, 16, 1681
Correction: Abdulrahim et al. Evaluation of Tissue Tropism and Horizontal Transmission of a Duck Enteritis Virus Vectored Vaccine in One-Day-Old Chicken. Viruses 2024, 16, 1681 Open
In the original publication [...]
View article: Evaluation of Tissue Tropism and Horizontal Transmission of a Duck Enteritis Virus Vectored Vaccine in One-Day-Old Chicken
Evaluation of Tissue Tropism and Horizontal Transmission of a Duck Enteritis Virus Vectored Vaccine in One-Day-Old Chicken Open
Herpesvirus of turkey (HVT) recombinant vector vaccines are widely used in the poultry industry. However, due to limitations in loading multiple foreign antigens into a single HVT vector, other viral vectors are urgently needed. Since chic…
View article: Assessing the association between the circulating levels of inflammatory cytokines and the risk of tuberculosis: A bidirectional two-sample mendelian randomization study
Assessing the association between the circulating levels of inflammatory cytokines and the risk of tuberculosis: A bidirectional two-sample mendelian randomization study Open
The study has illuminated the causal link between inflammatory cytokines and TB, thereby enhancing our comprehension of the potential mechanisms underlying TB pathogenesis. This discovery offers promising avenues for the identification of …
View article: Construction of pseudorabies virus variant attenuated vaccine: codon deoptimization of US3 and UL56 genes based on PRV gE/TK deletion strain
Construction of pseudorabies virus variant attenuated vaccine: codon deoptimization of US3 and UL56 genes based on PRV gE/TK deletion strain Open
Since 2011, pseudorabies based on the pseudorabies virus (PRV) variant has emerged as a serious health issue in pig farms in China. The PRV gE/TK or gE/gI/TK deletion strains protect against emerging PRV variants. However, these variants m…
View article: Impact factors of Blastocystis hominis infection in persons living with human immunodeficiency virus: a large-scale, multi-center observational study from China
Impact factors of Blastocystis hominis infection in persons living with human immunodeficiency virus: a large-scale, multi-center observational study from China Open
View article: A Novel Strategy of US3 Codon De-Optimization for Construction of an Attenuated Pseudorabies Virus against High Virulent Chinese Pseudorabies Virus Variant
A Novel Strategy of US3 Codon De-Optimization for Construction of an Attenuated Pseudorabies Virus against High Virulent Chinese Pseudorabies Virus Variant Open
In this study, we applied bacterial artificial chromosome (BAC) technology with PRVΔTK/gE/gI as the base material to replace the first, central, and terminal segments of the US3 gene with codon-deoptimized fragments via two-step Red-mediat…
View article: Construction and Mechanism of Microspheres with Tunable and Control Released Hydrophobicity: Ultra-Low-Density Proppants
Construction and Mechanism of Microspheres with Tunable and Control Released Hydrophobicity: Ultra-Low-Density Proppants Open
View article: Synergistic Effects of Rotavirus and Co-Infecting Viral Enteric Pathogens on Diarrheal Disease — Guangzhou City, Guangdong Province, China, 2019
Synergistic Effects of Rotavirus and Co-Infecting Viral Enteric Pathogens on Diarrheal Disease — Guangzhou City, Guangdong Province, China, 2019 Open
Implementing sensitive diagnostic techniques and comprehensive monitoring is paramount in identifying co-infections. Such strategies can provide physicians with critical insights into disease progression, thus considerably reducing the bur…
View article: A Cross-Sectional Survey of Iodized Salt Usage in Dining Establishments — 13 PLADs, China, 2021–2022
A Cross-Sectional Survey of Iodized Salt Usage in Dining Establishments — 13 PLADs, China, 2021–2022 Open
The data compiled could potentially fill the void in the national data concerning the use of iodized salt in dining establishments throughout China. It is of the utmost importance to increase the awareness of restaurant operators, particul…
View article: The “Hand as Foot” teaching method in pleural effusion
The “Hand as Foot” teaching method in pleural effusion Open
View article: Construction of a Novel Infectious Clone of Recombinant Herpesvirus of Turkey Fc-126 Expressing VP2 of IBDV
Construction of a Novel Infectious Clone of Recombinant Herpesvirus of Turkey Fc-126 Expressing VP2 of IBDV Open
The increased virulence of infectious bursal disease virus (IBDV) is a threat to the chicken industry. The construction of novel herpesvirus of turkey-vectored (HVT) vaccines expressing VP2 of virulent IBDV may be a promising vaccine candi…
View article: Establishment of a Special Platform for the Research of Prion and the Diagnosis of Human Prion Disease - China's Studies.
Establishment of a Special Platform for the Research of Prion and the Diagnosis of Human Prion Disease - China's Studies. Open
The studies of prions and prion disease usually need many special platforms and techniques that differ from those for classical microbes. Search of new biomarkers and establishment of new methods for the diagnosis of human prion diseases a…
View article: Extensive Disturbances of Intracellular Components and Dysfunctions of Biological Pathways in the Brain Tissues During Prion Infection - China's Studies.
Extensive Disturbances of Intracellular Components and Dysfunctions of Biological Pathways in the Brain Tissues During Prion Infection - China's Studies. Open
The study describes some of the major findings of changes in intracellular components and biological pathways in the brain during prion infection and hypothesizes some important physiological and pathological approaches mainly based on our…
View article: Activation of Innate Immunity and Autophagy in Brain Tissues with Prion Disease and Degradation of Abnormal PrPs in Cells - China's Studies.
Activation of Innate Immunity and Autophagy in Brain Tissues with Prion Disease and Degradation of Abnormal PrPs in Cells - China's Studies. Open
Unlike infectious diseases caused by conventional microbes, there are no detectable specific humoral or cellular immunoresponses to prion infection. However, extensive and active gliosis is observable in affected brain regions along with s…
View article: Characteristics of Different Types of Prion Diseases - China's Surveillance.
Characteristics of Different Types of Prion Diseases - China's Surveillance. Open
This report briefly described the establishment and implementation of national surveillance for human prion disease (PrD) in China. Reported cases came from Chinese surveillance network for PrD. Immunohistochemistry, Western blot, enzyme-l…
View article: The “Hand as Foot” teaching method in laryngomalacia
The “Hand as Foot” teaching method in laryngomalacia Open
View article: The “Hand as Foot” teaching method in tonsil enlargement grading
The “Hand as Foot” teaching method in tonsil enlargement grading Open
View article: Engineering and Characterization of Avian Coronavirus Mutants Expressing Fluorescent Reporter Proteins from the Replicase Gene
Engineering and Characterization of Avian Coronavirus Mutants Expressing Fluorescent Reporter Proteins from the Replicase Gene Open
Reverse genetics systems based on bacterial artificial chromosomes (BACs) are the most valuable systems in coronavirus research. Here, we describe the establishment of a reverse genetics system for the avian coronavirus strain Beaudette, t…
View article: Pachyderma in children: A clinically silent cutaneous fibromatosis
Pachyderma in children: A clinically silent cutaneous fibromatosis Open
View article: The “Hand as Foot” teaching method in thorax
The “Hand as Foot” teaching method in thorax Open
View article: The “Hand as Foot” figural teaching method in the rheumatoid arthritis
The “Hand as Foot” figural teaching method in the rheumatoid arthritis Open
View article: The “Hand as Foot” teaching method of nasal cavity
The “Hand as Foot” teaching method of nasal cavity Open
View article: The “Hand as Foot” teaching method in the respiratory membrane
The “Hand as Foot” teaching method in the respiratory membrane Open
View article: Identification of four insertion sites for foreign genes in a pseudorabies virus vector
Identification of four insertion sites for foreign genes in a pseudorabies virus vector Open
View article: Identification of the Suitable Insertion Site for Expression of Spike Gene of A Porcine Epidemic Diarrhea Virus Variant in A Pseudorabies Virus Vector
Identification of the Suitable Insertion Site for Expression of Spike Gene of A Porcine Epidemic Diarrhea Virus Variant in A Pseudorabies Virus Vector Open
Background: The emergence of variant porcine epidemic diarrhea virus (PEDV) strain and pseudorabies virus (PRV) in China in recent years has decreased the effectiveness of CV777 and Bartha K61 vaccines, causing significant loss to the swin…
View article: Up-regulation of PERK/Nrf2/HO-1 axis protects myocardial tissues of mice from damage triggered by ischemia-reperfusion through ameliorating endoplasmic reticulum stress
Up-regulation of PERK/Nrf2/HO-1 axis protects myocardial tissues of mice from damage triggered by ischemia-reperfusion through ameliorating endoplasmic reticulum stress Open
We, for the first time, discovered that up-regulation of PERK/Nrf2/HO-1 axis improved I/R-induced myocardial injury via reducing ERS-related signal molecules and downstream pro-apoptotic factors.
View article: Reduction of Postweaning Multisystemic Wasting Syndrome-Associated Clinical Symptoms by Virus-Like Particle Vaccine Against Porcine Parvovirus and Porcine Circovirus Type 2
Reduction of Postweaning Multisystemic Wasting Syndrome-Associated Clinical Symptoms by Virus-Like Particle Vaccine Against Porcine Parvovirus and Porcine Circovirus Type 2 Open
The porcine circovirus type 2 (PCV2) capsid (Cap) protein and porcine parvovirus (PPV) VP2 protein have been studied in vaccines to control postweaning multisystemic wasting syndrome (PMWS). Virus-like particle (VLP) vaccines are nonreplic…
View article: Table S2. Anatomy of two Permian greenschist- to blueschist-facies tectonic mélanges in the Solonker Suture Zone (Inner Mongolia, NE China): Evidences for divergent double subduction and soft collision
Table S2. Anatomy of two Permian greenschist- to blueschist-facies tectonic mélanges in the Solonker Suture Zone (Inner Mongolia, NE China): Evidences for divergent double subduction and soft collision Open
Table S2: Zircon U–Pb analytical results.