Hui Zhuan Tan
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View article: #1875 Physician-directed nudge for glycemic and lipid management in older patients with glomerulonephritis treated with immunosuppressants
#1875 Physician-directed nudge for glycemic and lipid management in older patients with glomerulonephritis treated with immunosuppressants Open
Background and Aims Glomerulonephritis and its treatment may be associated with cardiometabolic disease. Hence, optimizing glycemic and lipid control is important to reduce adverse health outcomes. We implemented an electronic medical reco…
View article: #1244 Metabolic disease assessment and control among adults diagnosed with severe podocytopathies
#1244 Metabolic disease assessment and control among adults diagnosed with severe podocytopathies Open
Background and Aims Primary podocytopathies such as minimal change disease and focal segmental glomerulosclerosis (FSGS) with nephrotic syndrome are treated with immunosuppressants such as high-dose steroids or calcineurin inhibitors. Thes…
View article: #2538 Remission and relapses in lupus nephritis among multi-racial Southeast Asians: a single center retrospective study
#2538 Remission and relapses in lupus nephritis among multi-racial Southeast Asians: a single center retrospective study Open
Background and Aims Lupus nephritis occurs in up to 60% of all patients with systemic lupus erythematosus (SLE) and has a relapsing/remitting course that can progress to kidney failure. This study aims to assess the treatment outcomes in a…
View article: #1360 Mortality and kidney failure among adults with primary podocytopathies
#1360 Mortality and kidney failure among adults with primary podocytopathies Open
Background and Aims Primary podocytopathies such as minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) with nephrotic syndrome are at risk of adverse outcomes. We aimed to describe the long-term kidney and patient o…
View article: ATP/P2X7 receptor/NLRP3 pathway facilitates renal tubular epithelial-myofibroblast transdifferentiation and interstitial fibrosis in rats with unilateral ureteral obstruction
ATP/P2X7 receptor/NLRP3 pathway facilitates renal tubular epithelial-myofibroblast transdifferentiation and interstitial fibrosis in rats with unilateral ureteral obstruction Open
Background P2X7 receptor (P2X7R) is reported involved in renal fibrosis and the activation of NOD-like receptor protein 3 (NLRP3) inflammasome. This study aimed to investigate the role of the P2X7R and NLRP3 in renal tubular epithelial-myo…
View article: Clinical Implementation of Nephrologist-Led Genomic Testing for Glomerular Diseases in Singapore: Rationale and Protocol
Clinical Implementation of Nephrologist-Led Genomic Testing for Glomerular Diseases in Singapore: Rationale and Protocol Open
Introduction: The early diagnosis and appropriate treatment of monogenic glomerular diseases can reduce kidney failure, avoid unnecessary investigations such as kidney biopsies and ineffective treatment with immunosuppressants, guide trans…
View article: #401 Cardiovascular risk evaluation in lupus nephritis and ANCA-associated vasculitis
#401 Cardiovascular risk evaluation in lupus nephritis and ANCA-associated vasculitis Open
Background and Aims Individuals with lupus nephritis (LN) and renal ANCA-associated vasculitis (AAV) have amplified cardiovascular risks. Early recognition and intervention for metabolic disease may mitigate cardiovascular risk. We aimed t…
View article: #933 Serum and kidney complement and severity of ANCA associated vasculitis in the kidney
#933 Serum and kidney complement and severity of ANCA associated vasculitis in the kidney Open
Background and Aims Kidney involvement in ANCA associated vasculitis (AAV) is commonly described as pauci-immune based on histological characteristics. However, we now know that the complement system is activated and contributes to the pat…
View article: AL amyloidosis: Singapore Myeloma Study Group consensus guidelines on diagnosis, treatment and management
AL amyloidosis: Singapore Myeloma Study Group consensus guidelines on diagnosis, treatment and management Open
AL amyloidosis is the most common form of systemic amyloidosis. However, the non-specific nature of presenting symptoms requires the need for a heightened clinical suspicion to detect unexplained manifestations in the appropriate clinical …
View article: Proton pump inhibitors and adverse kidney outcomes during immune checkpoint blockade: time to sound the alarm?
Proton pump inhibitors and adverse kidney outcomes during immune checkpoint blockade: time to sound the alarm? Open
Immune checkpoint inhibitors (ICIs) have significantly altered the treatment landscape for cancer in the last decade. However, their benefits are often offset by therapy-limiting immune-related adverse events (irAEs). Acute interstitial ne…
View article: Phenotyping Diabetes Mellitus on Aggregated Electronic Health Records from Disparate Health Systems
Phenotyping Diabetes Mellitus on Aggregated Electronic Health Records from Disparate Health Systems Open
Background: Identifying patients with diabetes mellitus (DM) is often performed in epidemiological studies using electronic health records (EHR), but currently available algorithms have features that limit their generalizability. Methods: …
View article: #6227 SPONTANEOUS REMISSION OF MEMBRANOUS VARIANT OF PGNMID WITH MONOCLONAL IGG2κ
#6227 SPONTANEOUS REMISSION OF MEMBRANOUS VARIANT OF PGNMID WITH MONOCLONAL IGG2κ Open
Background and Aims The clinical significance of the morphological patterns of glomerular injury and of each IgG subclass in proliferative glomerulonephritis (GN) with monoclonal immunoglobulin deposits (PGNMID) is not well understood. Lit…
View article: #2610 NURSE-LED OPTIMIZATION OF VOLUME AND BLOOD PRESSURE IN KIDNEY DISEASE – ENABLING AT MULTI-LEVELS USING A TECHNOLOGY (NOVELTY) PROGRAM
#2610 NURSE-LED OPTIMIZATION OF VOLUME AND BLOOD PRESSURE IN KIDNEY DISEASE – ENABLING AT MULTI-LEVELS USING A TECHNOLOGY (NOVELTY) PROGRAM Open
Background and Aims Fluid overload and hypertension are common in chronic kidney disease (CKD). They increase healthcare utilization due to frequent ambulatory consults and/or hospitalizations but can be avoided with self-management. We ev…
View article: #6294 UTILITY OF KIDNEY BIOPSY AND SPECTRUM OF BIOPSY PROVEN KIDNEY DISEASES IN PATIENTS WITH MALIGNANCY: A RETROSPECTIVE SINGLE-CENTER EXPERIENCE
#6294 UTILITY OF KIDNEY BIOPSY AND SPECTRUM OF BIOPSY PROVEN KIDNEY DISEASES IN PATIENTS WITH MALIGNANCY: A RETROSPECTIVE SINGLE-CENTER EXPERIENCE Open
Background and Aims Kidney biopsy may improve diagnostic accuracy and aid in the management of cancer patients with kidney diseases. However, literature on the utility of kidney biopsy in cancer patients and survivors is lacking. We aimed …
View article: Counselling for Kidney Biopsy and Immunosuppression in Glomerulonephritis Using Simulation
Counselling for Kidney Biopsy and Immunosuppression in Glomerulonephritis Using Simulation Open
not applicable for letter in response to recent publication in this journal
View article: MO1043: Influenza Vaccine Awareness and Acceptance Among Individuals with Glomerulonephritis and Renal Vasculitis During the Corononavirus Disease 2019 Pandemic
MO1043: Influenza Vaccine Awareness and Acceptance Among Individuals with Glomerulonephritis and Renal Vasculitis During the Corononavirus Disease 2019 Pandemic Open
BACKGROUND AND AIMS Patients with glomerulonephritis may have an increased risk of influenza infection and morbidity, but vaccine coverage remained low with little data on acceptance in glomerulonephritis. We aimed to assess influenza vacc…
View article: <scp>COVID</scp>‐19 vaccine acceptance among patients with glomerulonephritis
<span>COVID</span>‐19 vaccine acceptance among patients with glomerulonephritis Open
The recent Nephrology editorial highlighted concerns regarding post-vaccine glomerulonephritis relapse.1 However, the recent coronavirus disease 2019 (COVID-19) infection waves caused by the SARS-CoV-2 variants have added impetus to vaccin…
View article: POS-152 COMPARISON OF CLINICAL FEATURES AND OUTCOMES BETWEEN PATIENTS WITH DE NOVO ADULT-ONSET AND LATE-ONSET LUPUS NEPHRITIS
POS-152 COMPARISON OF CLINICAL FEATURES AND OUTCOMES BETWEEN PATIENTS WITH DE NOVO ADULT-ONSET AND LATE-ONSET LUPUS NEPHRITIS Open
Lupus nephritis (LN) affects approximately 60% of patients with systemic lupus erythematosus (SLE) and is a significant cause of morbidity. The influence of age of onset on presentation and disease outcomes is unclear. We aim to compare th…
View article: POS-133 PERCEIVED DIFFICULTIES IN HEALTH LITERACY COMPETENCIES AND DOMAINS AMONG PATIENTS WITH IMMUNOGLOBULIN A NEPHROPATHY
POS-133 PERCEIVED DIFFICULTIES IN HEALTH LITERACY COMPETENCIES AND DOMAINS AMONG PATIENTS WITH IMMUNOGLOBULIN A NEPHROPATHY Open
Immunoglobulin A (IgA) nephropathy is the most prevalent glomerulonephritis worldwide and treatment requires lifestyle modifications and high-risk immunosuppressive therapy. Health literacy (HL) can aid shared decision-making to optimize o…
View article: A Descriptive Evaluation of Health Literacy and Determinants of COVID-19 Vaccine Acceptance among Patients with IgA Nephropathy with High Vaccine Uptake
A Descriptive Evaluation of Health Literacy and Determinants of COVID-19 Vaccine Acceptance among Patients with IgA Nephropathy with High Vaccine Uptake Open
Aims: Shared decision-making regarding COVID-19 vaccination in IgA nephropathy involves the ability to handle health information regarding potential benefits and risk of flare, but few studies have evaluated health literacy in the context …
View article: Immune checkpoint inhibitor-induced acute tubulointerstitial nephritis
Immune checkpoint inhibitor-induced acute tubulointerstitial nephritis Open
A 69-year-old Chinese man was hospitalized for Common Terminology Criteria for Adverse Events (CTCAE) grade 2 acute kidney injury 8 months following treatment initiation with combination cytotoxic T-lymphocyte-associated protein 4 and prog…
View article: Health Literacy in Glomerulonephritis and Renal Vasculitis Attending Nephrology Clinics
Health Literacy in Glomerulonephritis and Renal Vasculitis Attending Nephrology Clinics Open
Aims: Glomerulonephritis is one of the leading causes of progressive chronic kidney disease worldwide and treatment requires shared decision-making to improve self-care and plan immunosuppressant therapy. However, information on health lit…
View article: Changes in metabolic parameters and adverse kidney and cardiovascular events during glomerulonephritis and renal vasculitis treatment in patients with and without diabetes mellitus
Changes in metabolic parameters and adverse kidney and cardiovascular events during glomerulonephritis and renal vasculitis treatment in patients with and without diabetes mellitus Open
DM was strongly associated with kidney failure and hospitalization for cardiovascular events in patients with biopsy-proven glomerulonephritis.
View article: The value of deep learning-based computer aided diagnostic system in improving diagnostic performance of rib fractures in acute blunt trauma
The value of deep learning-based computer aided diagnostic system in improving diagnostic performance of rib fractures in acute blunt trauma Open
Purpose To evaluate the value of a deep learning-based computer-aided diagnostic system (DL-CAD) in improving the diagnostic performance of acute rib fractures in patients with chest trauma. Methods CT images of 214 patients with acute blu…