Jie Chen
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View article: Implications of DNA damage response and immunotherapy in tumor therapy
Implications of DNA damage response and immunotherapy in tumor therapy Open
View article: Research on aging behaviors of insulating silicone oil for cable terminals based on chromatographic and spectroscopic analysis
Research on aging behaviors of insulating silicone oil for cable terminals based on chromatographic and spectroscopic analysis Open
With the widespread deployment of high-voltage cable terminals in power systems, insulating silicone oil has become a critical medium due to its superior dielectric and thermal properties. However, conventional diagnostic methods such as t…
View article: From overlooked metric to clinical action: ascending aortic length as a translational breakthrough in elective thoracic aneurysm surgery
From overlooked metric to clinical action: ascending aortic length as a translational breakthrough in elective thoracic aneurysm surgery Open
Background: Ascending aortic length (AAL) has long been overlooked in assessing the risk of adverse aortic events (AAE) in patients with ascending thoracic aortic aneurysm (ATAA). Our team was among the first globally to investigate AAL’s …
View article: Multidisciplinary Management in the Diabetes Reversal Clinic Promotes Diabetes Remission
Multidisciplinary Management in the Diabetes Reversal Clinic Promotes Diabetes Remission Open
View article: MOLECULAR CHARACTERIZATION AND TISSUE EXPRESSION OF THE <italic>BIM</italic> GENE IN <italic>MEGALOBRAMA AMBLYCEPHALA</italic> AND ITS RELATIONSHIP VERIFICATION WITH MAM-MIR-24-3
MOLECULAR CHARACTERIZATION AND TISSUE EXPRESSION OF THE <italic>BIM</italic> GENE IN <italic>MEGALOBRAMA AMBLYCEPHALA</italic> AND ITS RELATIONSHIP VERIFICATION WITH MAM-MIR-24-3 Open
View article: Ubiquitinated hepatitis D antigen-induced CD8+ T-cell responses inhibit HDV replication in HDV-infected liver organoids
Ubiquitinated hepatitis D antigen-induced CD8+ T-cell responses inhibit HDV replication in HDV-infected liver organoids Open
We successfully developed HBV/HDV superinfected liver organoids and suggest that Ub-S-HDAg facilitates DC maturation, inducing CD8+ T cell proliferation through the JAK/STAT signalling pathway, leading to a stronger antiviral im…
View article: Association between Non high density lipoprotein to high density lipoprotein cholesterol ratio and bone mineral density
Association between Non high density lipoprotein to high density lipoprotein cholesterol ratio and bone mineral density Open
View article: Hydrogels in cancer treatment: mapping the future of precision drug delivery
Hydrogels in cancer treatment: mapping the future of precision drug delivery Open
Background Current primary tumor treatments include curative resection, chemotherapy, and radiotherapy. However, these conventional methods lack precise drug delivery. Hydrogels, adaptable to the biological characteristics of different tum…
View article: Identifying Patients’ Preference During Their Hospital Experience. A Sentiment and Topic Analysis of Patient-Experience Comments via Natural Language Techniques
Identifying Patients’ Preference During Their Hospital Experience. A Sentiment and Topic Analysis of Patient-Experience Comments via Natural Language Techniques Open
The results of this study highlight the interpersonal and functional aspects of care, especially the interpersonal aspects, which are often the "moment of truth" during a service encounter when patients critically evaluate hospital service…
View article: Naphthalene Metabolites From Long‐Term Environmental Tobacco Smoke Induce the Aging of Retinal Pigment Epithelium
Naphthalene Metabolites From Long‐Term Environmental Tobacco Smoke Induce the Aging of Retinal Pigment Epithelium Open
Tobacco use is the main source of indoor air pollution and contains a variety of toxic components. The smoke from burning cigarettes is a key environmental risk factor that leads to accelerated aging and the occurrence of numerous diseases…
View article: Predicting protein stability changes upon mutations with dual-view ensemble learning from single sequence
Predicting protein stability changes upon mutations with dual-view ensemble learning from single sequence Open
Predicting the protein stability changes upon mutations is one of the effective ways to improve the efficiency of protein engineering. Here, we propose a dual-view ensemble learning-based framework, DVE-stability, for mutation-induced prot…
View article: Drug delivery agent that acts as a drug for synergistic activity
Drug delivery agent that acts as a drug for synergistic activity Open
View article: A Polymeric mRNA Vaccine Featuring Enhanced Site‐Specific mRNA Delivery and Inherent STING‐Stimulating Performance for Tumor Immunotherapy
A Polymeric mRNA Vaccine Featuring Enhanced Site‐Specific mRNA Delivery and Inherent STING‐Stimulating Performance for Tumor Immunotherapy Open
The development of mRNA delivery carriers with innate immune stimulation functions has emerged as a focal point in the field of mRNA vaccines. Nonetheless, the expression of mRNA in specific sites and innate immune stimulation at specific …
View article: A pilot randomized controlled trial of Kangmin Ⅰ decoction as a treatment for atopic eczema
A pilot randomized controlled trial of Kangmin Ⅰ decoction as a treatment for atopic eczema Open
View article: Mycorrhizal and nutrient controls of carbon sequestration in tropical rainforest soil
Mycorrhizal and nutrient controls of carbon sequestration in tropical rainforest soil Open
http://dx.doi.org/10.13039/501100001809 National Natural Science Foundation of China
View article: Inspired by Juslin: A New Model to Snapshot Music Stimuli’s Functionalities in Music Emotion Research
Inspired by Juslin: A New Model to Snapshot Music Stimuli’s Functionalities in Music Emotion Research Open
Since the turn of the 20th century, empirical studies using music stimuli to test key theories in music affects have mushroomed, in which selecting or designing music stimuli became a common practice. However, the majority of the studies d…
View article: Antifungal activity and mechanisms of 2-nonanone, a volatile organic compound produced by Bacillus velezensis TCS001, against Botrytis cinerea
Antifungal activity and mechanisms of 2-nonanone, a volatile organic compound produced by Bacillus velezensis TCS001, against Botrytis cinerea Open
View article: Assessment of the Correlations Among Three Stages of Maillard Reaction Products and Raw Material Chemical Components Of Fried Shiitake Mushroom (Lentinula Edodes) Crisps
Assessment of the Correlations Among Three Stages of Maillard Reaction Products and Raw Material Chemical Components Of Fried Shiitake Mushroom (Lentinula Edodes) Crisps Open
View article: Engineering the Substrate-Binding Pocket of Cellobiose 2-Epimerase for Enhancing Lactulose Biosynthesis
Engineering the Substrate-Binding Pocket of Cellobiose 2-Epimerase for Enhancing Lactulose Biosynthesis Open
View article: Research and Application of Key Parameters of Entry Formed by Roof‐Cutting in Inclined Coal Seam
Research and Application of Key Parameters of Entry Formed by Roof‐Cutting in Inclined Coal Seam Open
The dynamic and complex stress concentration phenomenon during overburden structure stabilization after inclined coal seam mining significantly affects the surrounding rock stability of gob‐side entries. To advance the application of entry…
View article: Genome Mining and Metabolite Profiling Uncover the Dual Functional Potential of Bacillus Velezensis Tcs001 as a Biocontrol Agent
Genome Mining and Metabolite Profiling Uncover the Dual Functional Potential of Bacillus Velezensis Tcs001 as a Biocontrol Agent Open
View article: Thermal management matters in photovoltaic–electrocatalysis for solar hydrogen production
Thermal management matters in photovoltaic–electrocatalysis for solar hydrogen production Open
Photovoltaic–electrolysis (PV‐EC) system currently exhibits the highest solar to hydrogen conversion efficiency (STH) among various technical routes. This perspective shifts the focus from the materials exploration in photovoltaics and ele…
View article: Study on the painting methods, amount and thermal properties of waterborne acrylic paint on bamboo-laminated lumber for furniture
Study on the painting methods, amount and thermal properties of waterborne acrylic paint on bamboo-laminated lumber for furniture Open
In order to understand the finishing effect of Waterborne Acrylic Paint under different painting methods and amount, bamboo-laminated lumber for furniture was coated with waterborne acrylic paint, then the effects of different painting met…
View article: Research progress of metalloporphyrin against neurodegene-rative diseases
Research progress of metalloporphyrin against neurodegene-rative diseases Open
Neurodegenerative diseases are a group of diseases caused by the degeneration and apoptosis of neurons in the brain and spinal cord, which seriously affect human ability of motion perception, memory and cognition. Peroxynitrite can cause o…
View article: Single cell-spatial transcriptomics and bulk multi-omics analysis of heterogeneity and ecosystems in hepatocellular carcinoma
Single cell-spatial transcriptomics and bulk multi-omics analysis of heterogeneity and ecosystems in hepatocellular carcinoma Open
View article: Remote Sensing Image Segmentation Using Vision Mamba and Multi-Scale Multi-Frequency Feature Fusion
Remote Sensing Image Segmentation Using Vision Mamba and Multi-Scale Multi-Frequency Feature Fusion Open
As remote sensing imaging technology continues to advance and evolve, processing high-resolution and diversified satellite imagery to improve segmentation accuracy and enhance interpretation efficiency emerg as a pivotal area of investigat…
View article: An electroactive microfluidic platform integrated with AM-pDEP focusing and side-counter design for selective cell sorting and single-cell quantification
An electroactive microfluidic platform integrated with AM-pDEP focusing and side-counter design for selective cell sorting and single-cell quantification Open
Rapid isolation and precise quantification of target cancer cells are crucial for precision medicine applications. Conventional fluorescence-based methods require bulky optical instrumentation and specialized expertise. Recent advances in …
View article: On-chip dielectrophoretic single-cell manipulation
On-chip dielectrophoretic single-cell manipulation Open
View article: Exploration and Practice of the Model of Integration of Production and Education in Higher Vocational Economics and Management
Exploration and Practice of the Model of Integration of Production and Education in Higher Vocational Economics and Management Open
In view of the problems encountered in the implementation of the integration of production and education, such as "school hot, enterprise cold", "emphasis on education over production", and "school and enterprise two sheets", this paper ai…
View article: Chronicles of racial discrimination: redlining’s influence on hypertension risk in women – Nurses Health Study II (1989 – 2019)
Chronicles of racial discrimination: redlining’s influence on hypertension risk in women – Nurses Health Study II (1989 – 2019) Open