Jiejie Lu
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View article: Effects of Ecological Environment on Physiological Indicators of Facial Skin in Hainan
Effects of Ecological Environment on Physiological Indicators of Facial Skin in Hainan Open
Objective To investigate the differences in facial skin physiological parameters among women living in distinct ecological environments across five regions of Hainan Province, China. Methods A total of 140 healthy adult women (28 per city)…
View article: Successful Treatment of Ixekizumab-Induced Paradoxical Eczematous Reaction with JAK Inhibitors: A Case Report
Successful Treatment of Ixekizumab-Induced Paradoxical Eczematous Reaction with JAK Inhibitors: A Case Report Open
With the widespread long-term use of biologics in plaque psoriasis, reports of paradoxical eczema caused by interleukin-17A (IL-17A) monoclonal antibodies are increasing. This paradoxical eczema (PE) can occasionally require termination of…
View article: Intense Pulsed Light Improves Facial Telangiectasia and Acne‐Induced Post‐Inflammatory Erythema in Systemic Lupus Erythematosus Patient: A Case Report
Intense Pulsed Light Improves Facial Telangiectasia and Acne‐Induced Post‐Inflammatory Erythema in Systemic Lupus Erythematosus Patient: A Case Report Open
Background Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease. Standard treatment typically involves corticosteroids, antimalarials, and immunosuppressants; however, long‐term corticosteroid use can lead to adv…
View article: Successful Treatment of Cutaneous Foreign Body Granuloma with JAK Inhibitor Abrocitinib and Prednisone: A Case Report
Successful Treatment of Cutaneous Foreign Body Granuloma with JAK Inhibitor Abrocitinib and Prednisone: A Case Report Open
This report provides preliminary evidence for JAK inhibitors' efficacy in managing refractory filler-induced FBG. Large-scale controlled trials are warranted to validate long-term safety and therapeutic benefits.
View article: Successful Treatment of Delayed Onset Nodules After Dermal Fillers Injection with Abrocitinib: A Case Report
Successful Treatment of Delayed Onset Nodules After Dermal Fillers Injection with Abrocitinib: A Case Report Open
Delayed-onset nodules (DONs) are masses that occurs primarily at or near the injection site stemmed from the injection of dermal fillers. This term is descriptive and encompasses a range of potential underlying diagnoses, including product…
View article: Histopathological Subtypes and Clinical Presentation of Seborrheic Keratosis: A 15-Year Retrospective Analysis of 1,169 Cases in Hainan, China
Histopathological Subtypes and Clinical Presentation of Seborrheic Keratosis: A 15-Year Retrospective Analysis of 1,169 Cases in Hainan, China Open
Our study confirms the acanthotic subtype as the most common histological type of SK, predominantly observed in patients aged 40-59 years. The head, face, and neck emerged as the most frequently involved sites. Ultraviolet radiation may pl…
View article: Abrocitinib Treatment for Localized Type of Generalized Pustular Psoriasis: A Case Report
Abrocitinib Treatment for Localized Type of Generalized Pustular Psoriasis: A Case Report Open
Generalized Pustular Psoriasis (GPP) is a recurrent dermatological condition characterized by widespread erythematous plaques, scaling, and sterile pustules. Notably, in a subset of patients, these lesions manifest exclusively in localized…
View article: A Case of Superficial Mycoses in a Patient with Systemic Lupus Erythematosus
A Case of Superficial Mycoses in a Patient with Systemic Lupus Erythematosus Open
Superficial mycoses are characterized by the infection of keratinized tissues such as the epidermis, hair, and nails. A 52-year-old woman from Hainan Province, China is reported in this study. The patient presents with large erythematous s…
View article: Giant Scapular Vascular Eccrine Spiroadenomas: A Rare Case Report
Giant Scapular Vascular Eccrine Spiroadenomas: A Rare Case Report Open
Giant vascular eccrine spiradenoma (GVES) is a dermal adnexal neoplasm, representing a malignant variant of eccrine spiradenoma. We report a case of giant scapular vascular eccrine spiroadenomas. This case is characterized by its large siz…
View article: Rare Case Report of Primary Active Pulmonary Tuberculosis During Ixekizumab Treatment for Plaque Psoriasis
Rare Case Report of Primary Active Pulmonary Tuberculosis During Ixekizumab Treatment for Plaque Psoriasis Open
Biologic agents have become a mainstay in the treatment of psoriasis, particularly in moderate to severe, refractory, and special types of the disease. Among these, ixekizumab is a humanized IgG4 monoclonal antibody targeting interleukin-1…
View article: A Case of Eosinophilic Pustular Folliculitis Misdiagnosed as Eczema
A Case of Eosinophilic Pustular Folliculitis Misdiagnosed as Eczema Open
Eosinophilic pustular folliculitis (EPF) is a rare skin disease. The typical skin lesions of classic EPF are localized on the upper limbs' face, trunk, and extensor surfaces. However, when the skin lesions initially appear on the palms and…
View article: Clinical and Pathological Analysis of 10 Cases of Eosinophilic Pustular Folliculitis
Clinical and Pathological Analysis of 10 Cases of Eosinophilic Pustular Folliculitis Open
We conducted a retrospective analysis of clinical and pathologic data from January 2020 to June 2023, focusing on 10 patients diagnosed with eosinophilic pustular folliculitis at our dermatology clinic. Four of the ten patients had the fir…
View article: The Role of Reflectance Confocal Microscopy in the Diagnosis and Therapeutic Evaluation of Rare Disease Eosinophilic Pustular Folliculitis
The Role of Reflectance Confocal Microscopy in the Diagnosis and Therapeutic Evaluation of Rare Disease Eosinophilic Pustular Folliculitis Open
Eosinophilic pustular folliculitis (EPF) is a rare skin disease for which the gold standard of diagnosis relies on the invasive examination of pathological tissue sections. However, due to its invasive nature, many patients tend to refuse …
View article: Successful Treatment of Minocycline-Induced Facial Hyperpigmentation with a Combination of Chemical Peels and Intense Pulsed Light
Successful Treatment of Minocycline-Induced Facial Hyperpigmentation with a Combination of Chemical Peels and Intense Pulsed Light Open
Minocycline is a tetracycline derivative antibiotic commonly used to treat acne, rosacea, and other inflammatory skin conditions. Taking minocycline risks inducing skin pigmentation. If minocycline-induced hyperpigmentation is not treated,…
View article: Vulvar Verruciform Xanthoma: A Comprehensive Literature Review
Vulvar Verruciform Xanthoma: A Comprehensive Literature Review Open
Verruciform xanthoma (VX) is a rare, benign, mucocutaneous, verrucous, papillary lesion. This paper retrospectively summarizes clinical and pathologic features of 32 vulvar verruciform xanthoma reported from China and abroad. The skin lesi…
View article: Clinical and Pathological Characteristics of 755 Patients with Skin Cancers in Hainan, China: A 12-Year Retrospective Study
Clinical and Pathological Characteristics of 755 Patients with Skin Cancers in Hainan, China: A 12-Year Retrospective Study Open
Lengbing Sun,1,2,* Jiejie Lu,1,* Ming Zhang,1 Xianxu Yang,1 Weiwei Wu,1 Qiao Liu2,3 1Department of Dermatology, The Fifth People’s Hospital of Hainan Province, Haikou, People’s Republic of China; 2School of Clinical Medicine, Jiangxi Unive…
View article: A Case Report of Porokeratosis Ptychotropica in a Chinese Man
A Case Report of Porokeratosis Ptychotropica in a Chinese Man Open
Porokeratosis ptychotropica is a rare form of porokeratosis characterized by dyskeratotic skin lesions around genital area or gluteal cleft. Herein, a case of porokeratosis ptychotropica was reported. The patient was a 35-year-old man, who…
View article: Founder Effects Contribute to the Population Genetic Structure of the Major Dermatophytosis Pathogen Trichophyton rubrum on Hainan Island, China
Founder Effects Contribute to the Population Genetic Structure of the Major Dermatophytosis Pathogen Trichophyton rubrum on Hainan Island, China Open
This study is the first to discuss general ecological and evolutionary principles related to pathogenic fungi. Our findings reveal a founder effect during the origination of T. rubrum on Hainan Island and provide guidance regarding prevent…
View article: Pemphigus Herpetiformis-Type Drug Reaction Caused by Programmed Cell Death Protein-1 Inhibitor Treatment
Pemphigus Herpetiformis-Type Drug Reaction Caused by Programmed Cell Death Protein-1 Inhibitor Treatment Open
Reports of immune-related adverse events caused by programmed cell death protein-1 inhibitor are becoming increasingly frequent. Herein, we report the first case of pemphigus herpetiformis-type drug reaction presented after the treatment o…
View article: Wells Syndrome Successfully Treated with Tripterygium Glycosides
Wells Syndrome Successfully Treated with Tripterygium Glycosides Open
Wells syndrome (WS), also known as eosinophilic cellulitis, is a rare inflammatory dermatosis of unknown etiology that typically presents with pruritic cellulitis-like plaques. The first line treatment options for WS are topical or systemi…
View article: Clinical and Pathological Characteristics of 755 Patients with Skin Cancers in Hainan, China: A 12-Year Retrospective Study
Clinical and Pathological Characteristics of 755 Patients with Skin Cancers in Hainan, China: A 12-Year Retrospective Study Open
Background : Skin cancers are the most frequent types of all malignant tumours with increasing incidence rates worldwide. Objectives : This study aimed to analyze the clinical–pathological characteristics of skin cancers in patients visite…
View article: Zosteriform Lymphangitic Metastases of Eccrine Porocarcinoma
Zosteriform Lymphangitic Metastases of Eccrine Porocarcinoma Open
Eccrine porocarcinoma (EPC) is a rare malignant neoplasm which originates from the intraepidermal portion of eccrine sweat glands or acrosyringium. Here, we report a unique case of cutaneous metastases of EPC presenting with an erosive pla…