Jill Gregory
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View article: Legal and ethical considerations around the use of existing illustrations to generate new illustrations in the anatomical sciences
Legal and ethical considerations around the use of existing illustrations to generate new illustrations in the anatomical sciences Open
It is likely existing anatomical illustrations are often used as the basis for new illustrative works, given not all illustrators have access to human tissues, bodies, or prosections on which to base their illustrations. Potential issues a…
View article: Association between Exposure to Metals during Pregnancy, Childhood Gut Microbiome, and Risk of Intestinal Inflammation in Late Childhood
Association between Exposure to Metals during Pregnancy, Childhood Gut Microbiome, and Risk of Intestinal Inflammation in Late Childhood Open
Alterations to the gut microbiome and exposure to metals during pregnancy have been suggested to impact inflammatory bowel disease. Nonetheless, how prenatal exposure to metals eventually results in long-term effects on the gut microbiome,…
View article: Sensory neurons promote immune homeostasis in the lung
Sensory neurons promote immune homeostasis in the lung Open
Cytokines employ downstream Janus kinases (JAKs) to promote chronic inflammatory diseases. JAK1-dependent type 2 cytokines drive allergic inflammation, and patients with JAK1 gain-of-function (GoF) variants develop atopic dermatitis (AD) a…
View article: Prenatal Lead Exposure Is Associated with Reduced Abundance of Beneficial Gut Microbial Cliques in Late Childhood: An Investigation Using Microbial Co-Occurrence Analysis (MiCA)
Prenatal Lead Exposure Is Associated with Reduced Abundance of Beneficial Gut Microbial Cliques in Late Childhood: An Investigation Using Microbial Co-Occurrence Analysis (MiCA) Open
Many analytical methods used in gut microbiome research focus on either single bacterial taxa or the whole microbiome, ignoring multibacteria relationships (microbial cliques). We present a novel analytical approach to identify microbial c…
View article: Weighted quantile sum regression and machine-learning assisted discovery of interactions between environmental chemicals in child neurodevelopment
Weighted quantile sum regression and machine-learning assisted discovery of interactions between environmental chemicals in child neurodevelopment Open
BACKGROUND AND AIM: A growing body of literature suggests that developmental exposure to individual or mixtures of environmental chemicals (ECs) is associated with autism spectrum disorder (ASD). However, evaluating interactive effects wit…
View article: Machine Learning Assisted Discovery of Interactions between Pesticides, Phthalates, Phenols, and Trace Elements in Child Neurodevelopment
Machine Learning Assisted Discovery of Interactions between Pesticides, Phthalates, Phenols, and Trace Elements in Child Neurodevelopment Open
A growing body of literature suggests that developmental exposure to individual or mixtures of environmental chemicals (ECs) is associated with autism spectrum disorder (ASD). However, investigating the effect of interactions among these E…
View article: Molecular Profiling of COVID-19 Autopsies Uncovers Novel Disease Mechanisms
Molecular Profiling of COVID-19 Autopsies Uncovers Novel Disease Mechanisms Open
Background Current understanding of COVID-19 pathophysiology is limited by disease heterogeneity, complexity, and a paucity of studies evaluating patient tissues with advanced molecular tools. Methods Autopsy tissues from two COVID-19 pati…
View article: Targeted Parathyroidectomy—Use of the Atraumatic Microvascular Clamp
Targeted Parathyroidectomy—Use of the Atraumatic Microvascular Clamp Open
This diagnostic study describes the use of a microvascular clamp to identify adenomas in patients with hyperparathyroidism.
View article: Long-Term Behavioral Effects of Post-weaning Social Isolation in Males and Females
Long-Term Behavioral Effects of Post-weaning Social Isolation in Males and Females Open
Adolescence is a developmental period associated with vast neural and behavioral changes which are accompanied by altered sensitivity to stimuli, both stressful and rewarding. Perturbations, especially stressful stimuli, during this period…
View article: The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening
The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening Open
Current applications of human induced pluripotent stem cell (hiPSC) technologies in patient-specific models of neurodegenerative and neuropsychiatric disorders tend to focus on neuronal phenotypes. Here, we review recent efforts toward adv…