J.D. Hendricks
YOU?
Author Swipe
View article: A World Apart? Bridging the Gap Between Theory and Applied Social Gerontology
A World Apart? Bridging the Gap Between Theory and Applied Social Gerontology Open
This article is based on the premise that there is inadequate attention to the link between theory and applied research in social gerontology. The article contends that applied research studies do not often or effectively employ a theoreti…
View article: The importance of carcinogen dose in chemoprevention studies: quantitative interrelationships between, dibenzo[a,l]pyrene dose, chlorophyllin dose, target organ DNA adduct biomarkers and final tumor outcome
The importance of carcinogen dose in chemoprevention studies: quantitative interrelationships between, dibenzo[a,l]pyrene dose, chlorophyllin dose, target organ DNA adduct biomarkers and final tumor outcome Open
Chlorophyllin (CHL) is a potent antimutagen in vitro, an effective anti-carcinogen in several animal models, and significantly reduced urinary biomarkers of aflatoxin B(1) (AFB(1)) exposure in a human population. Here we report an expanded…
View article: Modulation of aflatoxin-B1 hepatocarcinogenesis in trout by dehydroepiandrosterone: initiation/post-initiation and latency effects
Modulation of aflatoxin-B1 hepatocarcinogenesis in trout by dehydroepiandrosterone: initiation/post-initiation and latency effects Open
Previously, we demonstrated that dehydroepiandrosterone (DHEA) enhances aflatoxin B1 (AFB1) hepatocarcinogenesis in trout when administered following AFB1 exposure. This paper examines the effect of DHEA on tumor latency and the comparativ…
View article: The Search for New Solutions
The Search for New Solutions Open
Conceptual development in social gerontology is overdue for infusions of innovative thinking. To date, theorizing has evolved in dialectical fashion from an emphasis on individual adaptation, to structural constraints, to interactive proce…
View article: Fish models for environmental carcinogenesis: the rainbow trout.
Fish models for environmental carcinogenesis: the rainbow trout. Open
Progress over the past 30 years has revealed many strengths of the rainbow trout as an alternative model for environmental carcinogenesis research. These include low rearing costs, an early life-stage ultrasensitive bioassay, sensitivity t…
View article: Inter-relationships among aflatoxin B1 (AFB1) metabolism, DNA-binding, cytotoxicity, and hepatocarcinogenesis in rainbow trout Oncorhynchus mykiss
Inter-relationships among aflatoxin B1 (AFB1) metabolism, DNA-binding, cytotoxicity, and hepatocarcinogenesis in rainbow trout Oncorhynchus mykiss Open
The roles of metabolism in aflatoxin B, (AFBI) cytotoxicity and of cytotoxicity in AFB, hepatocarcinogenesis in rainbow trout Oncorhynchus mykiss have been examined.Groups of rainbow trout fry were exposed to carcinogenic aqueous solutions…
View article: Rare renal neoplasms in Salmo gairdneri exposed to MNNG (N-methyl-N'-nitro-N-nitroso-guanidine)
Rare renal neoplasms in Salmo gairdneri exposed to MNNG (N-methyl-N'-nitro-N-nitroso-guanidine) Open
N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) is a potent liver, stomach, kidney, and swimbladder carcinogen in rainbow trout Salmo gairdnen.Histopathological examination of tissues from trout exposed as fry to 50 ppm MNNG for 30 min reveale…
View article: Enhancement of aflatoxin B1 and N-methyl-N'-nitro-N-nitrosoguanidine hepatocarcinogenesis in rainbow trout Salmo gairdneri by 17-B-estradiol and other organic chemicals
Enhancement of aflatoxin B1 and N-methyl-N'-nitro-N-nitrosoguanidine hepatocarcinogenesis in rainbow trout Salmo gairdneri by 17-B-estradiol and other organic chemicals Open
Twenty-one-day-old rainbow trout Salmo gairdneri embryos were exposed to static solutions of aflatoxin B, (AFB,) (0.5 pprn for 30 min) or N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) (50 ppm for 60 min) to initiate neoplasms of the liver (A…
View article: Initiation, promotion, and inhibition of carcinogenesis in rainbow trout.
Initiation, promotion, and inhibition of carcinogenesis in rainbow trout. Open
The identification of etiological agents in feral fish neoplasia epizootics has been hampered in part by the lack of suitable fish models, and complicated by the likely existence of environmental agents which can act to stimulate or reduce…