Explanipedia

Age differences in spontaneous cerebrovascular reactivity at rest Open

Allison Engstrom, Shubir Dutt, John Paul M. Alitin, Arunima Kapoor, Trevor Lohman , et al. · 2025

Deficits in cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) may indicate vulnerability to vascular dysfunction and cognitive impairment. Prior findings on age-related change in CVR are mixed, and no studies to date have inve…

Relating Domain-Specific Risk-Taking Behavior to Cognitive Functions in Older Adults Open

Leah H. Waltrip, Silvia Chapman, Madison Bouchard-Liporto, Jillian L. Joyce, Michael R. Kann , et al. · 2025

Background/Objectives: Risk taking, a crucial component of decision-making, is domain-specific. However, most literature has focused on financial risk-taking in relation to cognitive functioning. The current study investigated the associat…

Relating Domain-Specific Risk-Taking Behavior to Cognitive Functions in Older Adults Open

Leah Waltrip, Silvia Chapman, Madison Bouchard-Liporto, Jillian L. Joyce, Michael R. Kann , et al. · 2025

Background/Objectives: Risk taking, a crucial component of decision-making, is domain-specific. However, most literature has focused on financial risk-taking in relation to cognitive functioning. The current study investigated the associat…

Digital Cognitive Screening Outcomes in Older Women at the Annual Well Woman Visit Open

Sandra Rizer, Jillian L. Joyce, Samantha A. Dargie, Silvia Chapman, David J. Libon , et al. · 2024

Background Mild cognitive impairment, a precursor to Alzheimer’s disease and related disorders (ADRD), is widely underdiagnosed. Routine screenings are key for identifying older adults with emerging neurodegenerative disease. As women have…

Preliminary Findings from EMPOWER: Evaluating Memory as Part of Women’s Routine Care Open

Jillian L. Joyce, Stephanie Cosentino, Sandra Rizer, Samantha A. Dargie, Silvia Chapman , et al. · 2024

Background Despite evidence that Alzheimer’s disease (AD) related pathological changes occur earlier in women than men, women are diagnosed later. To address this care disparity, the Evaluating Memory as Part of Women’s Routine Care (EMPOW…

Risk‐taking behavior in older adults is related to cognitive outcomes in a domain‐specific manner Open

Leah H. Waltrip, Jillian L. Joyce, Silvia Chapman, Stephanie Cosentino, Preeti Sunderaraman · 2023

Background Risk tolerance, a crucial component of decision‐making, has been shown to be highly domain‐specific (Blais, 2006). Nevertheless, when risk‐taking behavior is studied in the context of aging, it is almost exclusively examined usi…

Relationship between psychiatric symptoms and bidirectional change in subjective cognitive decline Open

Michael Kann, Silvia Chapman, Jillian L. Joyce, Leah H. Waltrip, Peter Zeiger , et al. · 2023

Background Subjective Cognitive Decline (SCD) is increasingly recognized as a prodromal risk state for Alzheimer’s disease. However, relatively little is known about trajectories of SCD within cognitively normal older adults, or the factor…

The Effect of the COVID‐19 Pandemic on Subjective Cognitive Decline and Mood Open

Angelique Loor, Silvia Chapman, Jillian L. Joyce, Leah H. Waltrip, Sandra Rizer , et al. · 2023

Background Subjective Cognitive Decline (SCD) is being recognized as one of the earliest clinical signs of Alzheimer’s disease (AD). However, SCD is susceptible to a range of task factors (e.g., how SCD is measured) and person factors (e.g…

Sex/gender differences in subjective cognitive decline’s association to cognition and depression Open

Jillian L. Joyce, Silvia Chapman, Katherine A. Gifford, Shaina Shagalow, Leah H. Waltrip , et al. · 2023

Background Despite the fact that women are more likely to develop Alzheimer’s disease (AD) than men, and develop pathological changes at an earlier age, women often receive diagnoses later. This disparity is possibly due to women’s verbal …

79 Brief Subjective Memory Screener Predicts Memory Dysfunction Open

Jillian L. Joyce, Sandra Rizer, Shaina Shagalow, Leah Waltrip, Silvia Chapman , et al. · 2023

Objective: Alzheimer’s disease (AD) is expected to affect over 7 million older Americans by 2025. Development of fast and inexpensive screening measures for routine screening is critical for identifying those suffering from the earliest st…

88 Single Trial of Biber Figure Learning Test Captures Subjective Cognitive Decline Open

Michael Kann, Peter Zeiger, Silvia Chapman, Shaina Shagalow, Jillian L. Joyce , et al. · 2023

Objective: The Biber Figure Learning Test (BFLT) is a serial figure learning assessment previously been shown to be sensitive to various biomarkers of the aging brain. BFLT is an extensive assessment requiring about 30 minutes for administ…

39 The role of Subjective Cognitive Decline and Aging Perceptions in Help Seeking across White and Non-White older adults Open

Martina Azar, Jillian L. Joyce, Silvia Chapman, Sandra Rizer, Leah Waltrip , et al. · 2023

Objective: Research has indicated that racial and ethnic minoritized groups in the United States are disproportionately affected by dementia (e.g., Alzheimer’s disease), and seek help (HS) later in the disease course, if at all. It has als…

49 Health Literacy and Well-Being in Older Adults Open

Miji A Suhr, Silvia Chapman, Jillian L. Joyce, Yaakov Stern, Stephanie Cosentino , et al. · 2023

Objective: Although health problems are often a natural consequence of aging, many older adults struggle to manage their health care problems. Health literacy refers to the ability to access, process, and use health information to make app…

18 Which cognitive complaints among older adults are more concerning than others? Analysis of items in a Subjective Cognitive Decline Questionnaire Open

Michelle Hernandez, Jillian L. Joyce, Silvia Chapman, Martina Azar, Leah Waltrip , et al. · 2023

Objective: Subjective Cognitive Decline (SCD) is the self-reported experience of one’s own declining cognition prior to objective impairment on clinical neuropsychological testing. While SCD is a promising marker of preclinical Alzheimer’s…

12 Examining Illness Perception Among Cognitively Healthy Older Adults Open

Elizabeth Soto, Martina Azar, Jillian L. Joyce, Silvia Chapman, Leah Waltrip , et al. · 2023

Objective: An individual with dementia suffers from cognitive decline affecting not only memory but at least one of the other domains, such as personality, praxis, abstract thought, language, executive functioning, attention, and social sk…

84 Utilizing the DSM-5 Cross Cutting Measure to Characterize the Neuropsychiatric Correlates of Subjective and Objective Cognition Open

Leah Waltrip, Jillian L. Joyce, Silvia Chapman, Sandra Rizer, Shaina Shagalow , et al. · 2023

Objective: Historically, psychiatric conditions and neurodegenerative diseases have been considered differential diagnoses in older adults with cognitive impairment. However, recent evidence has shown that neuropsychiatric symptoms may be …

92 Biber Figure Learning Test Outperforms Other Cognitive Measures in Predicting Subjective Cognitive Decline Open

Shaina Shagalow, Silvia Chapman, Peter J. Zeiger, Michael R. Kann, Leah Waltrip , et al. · 2023

Objective: Subjective Cognitive Decline (SCD), the perception of deteriorating cognition in the absence of apparent impairment on objective testing, has gained momentum in recent literature as a risk marker for AD. Traditional neuropsychol…

93 Impact of Childhood Socioeconomic Status on Subjective Cognitive Decline Open

Stella M. Garriga, Jillian L. Joyce, Martina Azar, Leah Waltrip, Peter Zeiger , et al. · 2023

Objective: Subjective cognitive decline (SCD) is increasingly being considered one of the earliest clinical signs of Alzheimer’s Disease (AD). Certain characteristics of early life, such as childhood socioeconomic status (SES), have been a…

50 Remote Assessment has Minimal Effect on Test-Retest Reliability Among Older Adults with Essential Tremor Open

Sandra Rizer, Silvia Chapman, Jillian L. Joyce, Nikki Delgado, Margaret McGurn , et al. · 2023

Objective: The COVID-19 pandemic increased utilization of remote assessment to allow clinicians and researchers to continue valuable work while maintaining quarantine guidelines. With guidelines relaxing, researchers have returned to in-pe…

4 Ushering in Modern and Objective Ways of Assessing Financial Decision Making in Clinical Settings: The Development and Validation of an Online Money Management Credit Card Task Open

Preeti Sunderaraman, Silvia Chapman, Whitney Hartstone, Jillian L. Joyce, Yaakov Stern , et al. · 2023

Objective: Historically, assessment of financial decision making (FDM) has largely relied on self- or informant-reports, and paper-and-pencil tests. However, subjective report is prone to under/over-estimation biases, and most available te…

Education as a Moderator of Help Seeking Behavior in Subjective Cognitive Decline Open

Martina Azar, Silvia Chapman, Jillian L. Joyce, Maria T. Schultheis, Zoe Zhang , et al. · 2023

Objective: Disparities in Alzheimer disease (AD) and differences in help seeking (HS) across sociodemographic groups warrant public health concern. Research addressing such disparities must shift toward the earliest clinical manifestations…

Financial Behaviors and Experiences of Financial Loss in those with Alzheimer’s disease and Frontotemporal Dementia: Preliminary findings from a survey Open

Claudine K. Narayan, Colin Stein, Jeannie M. Ake, Andrea Benavides, Edward D. Huey , et al. · 2023

Background Older adults are increasingly experiencing financial loss, with annual costs estimated to be about $2.9 billion. The risk of experiencing financial loss is magnified in those with neurodegenerative conditions, including Alzheime…

Association of Subjective Cognitive Decline With Progression to Dementia in a Cognitively Unimpaired Multiracial Community Sample Open

Silvia Chapman, Miguel Arce Rentería, Jordan D. Dworkin, Stella M. Garriga, Megan S. Barker , et al. · 2022

Overall results of this study support SCD as a prodromal marker of dementia in a multiracial community sample, and in Latinx and non-Latinx Black individuals in particular. Because models examining the risk of dementia were adjusted for ba…

INVESTIGATION INTO THE PREDICTORS OF HELP-SEEKING BEHAVIOR IN OLDER ADULTS Open

Michael Kann, Silvia Chapman, Martina Azar, Jillian L. Joyce, Leah Waltrip , et al. · 2022

Early help seeking (HS) among patients with emerging Alzheimer’s disease and related dementias (AD/ADRD) can have considerable implications for treatment course, access to clinical trials, lifestyle, and future quality of life. Previous st…

Examining the Role of Aging Perceptions in Subjective Cognitive Decline Open

Silvia Chapman, David Weiss, Hana M. Broulíková, Preeti Sunderaraman, Megan S. Barker , et al. · 2022

Objective: While subjective cognitive decline (SCD) is gaining ground as a “preclinical” risk state for Alzheimer disease, its utility depends on our understanding of the factors linked to SCD. Rarely examined sociocultural factors includi…

Perinatal Depression and Breastfeeding: A Mixed Methods Study Among South Sudanese Refugees in the West Nile Region in Uganda Open

Christine Walters, Joel Komakech, Hasina Rakotomanana, Margaret Kabahenda, Jillian L. Joyce , et al. · 2022

The specific study objectives were: 1) to identify perceived common stressors among parents in refugee settlements, 2) to analyze the associations of perinatal depression and early initiation of breastfeeding and 3) to analyze the associat…

Correction to: Self-awareness for financial decision making abilities is linked to right temporal cortical thickness in older adults Open

Preeti Sunderaraman, Seonjoo Lee, Eleanna Varangis, Christian Habeck, Silvia Chapman , et al. · 2022

Subjective Cognitive Decline Is More Accurate When Metamemory Is Better Open

Silvia Chapman, Jillian L. Joyce, Megan S. Barker, Preeti Sunderaraman, Sandra Rizer , et al. · 2022

Objective Subjective cognitive decline (SCD) has emerged as one of the first manifestations of Alzheimer’s disease (AD). However, discrepancies in its relationship with tests of memory and other cognitive abilities have hindered SCD’s diag…

Financial decision‐making and self‐awareness for financial decision‐making is associated with white matter integrity in older adults Open

Preeti Sunderaraman, Yunglin Gazes, Gema Ortiz, Christopher Langfield, Ashley Mensing , et al. · 2022

Financial decision‐making (FDM) and awareness of the integrity of one's FDM abilities (or financial awareness) are both critical for preventing financial mistakes. We examined the white matter correlates of these constructs and hypothesize…

White matter integrity is associated with self‐awareness of financial decision‐making in cognitively healthy older adults Open

Preeti Sunderaraman, Yunglin Gazes, Gema Ortiz, Silvia Chapman, Jillian L. Joyce , et al. · 2021

Background Reduced awareness of one’s financial decision‐making abilities (financial awareness) can result in costly financial mistakes (e.g., forgetting to pay credit card dues) and increase one’s vulnerability to financial exploitation (…

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