Jiming Liang
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View article: Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects
Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects Open
As the most common primary malignant bone tumor, osteosarcoma (OS) is characterized by drug resistance and poor prognosis, highlighting the urgent need for promising therapeutic agents. Formononetin (FMN), a natural product derived from Sp…
View article: Prognostic significance of T cells and NK cells in osteosarcoma: a dual-center retrospective study
Prognostic significance of T cells and NK cells in osteosarcoma: a dual-center retrospective study Open
View article: Single-cell and spatial transcriptomics reveal metastasis mechanism and microenvironment remodeling of lymph node in osteosarcoma
Single-cell and spatial transcriptomics reveal metastasis mechanism and microenvironment remodeling of lymph node in osteosarcoma Open
View article: Interaction gene set between osteoclasts and regulatory <scp>CD4<sup>+</sup></scp> T cells can accurately predict the prognosis of patients with osteosarcoma
Interaction gene set between osteoclasts and regulatory <span>CD4<sup>+</sup></span> T cells can accurately predict the prognosis of patients with osteosarcoma Open
Osteoclasts (OCs) and regulatory CD4 + T cells (CD4 + Tregs) are important components in the tumor microenvironment (TME) of osteosarcoma. In this study, we collected six osteosarcoma samples from our previous study (GSE162454). We also in…
View article: A novel molecular signature for predicting prognosis and immunotherapy response in osteosarcoma based on tumor-infiltrating cell marker genes
A novel molecular signature for predicting prognosis and immunotherapy response in osteosarcoma based on tumor-infiltrating cell marker genes Open
Background Tumor infiltrating lymphocytes (TILs), the main component in the tumor microenvironment, play a critical role in the antitumor immune response. Few studies have developed a prognostic model based on TILs in osteosarcoma. Methods…
View article: Treatment of Posterior Malleolus Fracture through Posterolateral Approach
Treatment of Posterior Malleolus Fracture through Posterolateral Approach Open
Posterior malleolus fractures are quite common and usually result from rotational ankle injuries. For the management of posterior malleolus fractures, more studies are still required, though it is already well-recognized for medial and lat…