Jimmy Yu Wai Chan
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View article: Detection of CSF1 gene derangement in ‘sclerosing mucoepidermoid carcinoma with eosinophilia’ of the parotid gland masquerading as Langerhans cell histiocytosis
Detection of CSF1 gene derangement in ‘sclerosing mucoepidermoid carcinoma with eosinophilia’ of the parotid gland masquerading as Langerhans cell histiocytosis Open
View article: Cell transplantation techniques for cartilage restoration
Cell transplantation techniques for cartilage restoration Open
Background: Focal articular chondral lesions are a common finding among patients presenting with knee pain. If symptomatic and unresponsive to conservative treatment, cell transplantation techniques offer a unique solution to address large…
View article: Novel approach to reduce SARS-CoV-2 transmission during trans-oral robotic surgery
Novel approach to reduce SARS-CoV-2 transmission during trans-oral robotic surgery Open
View article: Impact of COVID-19 Pandemic on Patients Perceptions of Safety and Need for Elective Foot and Ankle Surgery in the United States
Impact of COVID-19 Pandemic on Patients Perceptions of Safety and Need for Elective Foot and Ankle Surgery in the United States Open
Category: Ankle; Ankle Arthritis; Arthroscopy; Bunion; Hindfoot; Lesser Toes; Midfoot/Forefoot; Sports Introduction/Purpose: With the development of the COVID-19 pandemic, elective foot and ankle surgeries were delayed throughout the U.S. …
View article: Recommendations for surgical management of recurrent nasopharyngeal carcinoma during <scp>COVID</scp>‐19 pandemic
Recommendations for surgical management of recurrent nasopharyngeal carcinoma during <span>COVID</span>‐19 pandemic Open
Nasopharyngeal carcinoma is endemic in southern parts of China including Hong Kong. Primary treatment entails radiotherapy ± chemotherapy depending on disease stage at presentation. Surgery is offered as a means of salvage for persistent a…
View article: Tracheostomy during <scp>COVID</scp>‐19 pandemic—Novel approach
Tracheostomy during <span>COVID</span>‐19 pandemic—Novel approach Open
Background This study describes a novel approach in reducing SARS‐CoV‐2 transmission during tracheostomy. Methods Five patients underwent tracheostomy between April 1, 2020 and April 17, 2020. A clear and sterile plastic drape was used as …
View article: Transpalatal Approaches to the Skull Base and Reconstruction: Indications, Technique, and Associated Morbidity
Transpalatal Approaches to the Skull Base and Reconstruction: Indications, Technique, and Associated Morbidity Open
Multiple anterior surgical approaches are available to obtain access to the nasopharynx, clivus, and craniocervical junction. These include the direct and transoral robotic surgery transpalatal, maxillary swing, and endoscopic endonasal ap…
View article: Conservation of personal protective equipment for head and neck cancer surgery during <scp>COVID</scp>‐19 pandemic
Conservation of personal protective equipment for head and neck cancer surgery during <span>COVID</span>‐19 pandemic Open
Background COVID‐19 pandemic has led to a global shortage of personal protective equipment (PPE). This study aims to stratify face shield needs when performing head and neck cancer surgery. Methods Fifteen patients underwent surgery betwee…
View article: Management of locally recurrent nasopharyngeal carcinoma
Management of locally recurrent nasopharyngeal carcinoma Open
View article: Reply to Human papillomavirus and World Health Organization type III nasopharyngeal carcinoma: Multicenter study from an endemic area in Southern China
Reply to Human papillomavirus and World Health Organization type III nasopharyngeal carcinoma: Multicenter study from an endemic area in Southern China Open
Nasopharyngeal carcinoma is common in the southern part of China, which includes Hong Kong. In this endemic part of the world, it is well known that Epstein-Barr virus (EBV) plays an important role in the etiology of the cancer, and this i…
View article: Application of three-dimensional printing technology in orbital floor fracture reconstruction
Application of three-dimensional printing technology in orbital floor fracture reconstruction Open
View article: Epstein‑Barr virus‑encoded microRNA BART7 downregulates major histocompatibility complex class I chain‑related peptide A and reduces the cytotoxicity of natural killer cells to nasopharyngeal carcinoma
Epstein‑Barr virus‑encoded microRNA BART7 downregulates major histocompatibility complex class I chain‑related peptide A and reduces the cytotoxicity of natural killer cells to nasopharyngeal carcinoma Open
Evasion from natural killer (NK) cell surveillance enables cancer to proliferate and spread at the early stages. NK cells mediate specific cytolysis by activation of the triggering receptors on their cell surface, of which the communicatio…
View article: Human papillomavirus and World Health Organization type III nasopharyngeal carcinoma: Multicenter study from an endemic area in Southern China
Human papillomavirus and World Health Organization type III nasopharyngeal carcinoma: Multicenter study from an endemic area in Southern China Open
BACKGROUND The current study was conducted to study the incidence of human papillomavirus (HPV)‐associated nasopharyngeal carcinoma (NPC) in Southern China and the corresponding treatment outcome. METHODS A retrospective chart review with …
View article: Head and neck cancer in Hong Kong
Head and neck cancer in Hong Kong Open
Head and neck cancer is a major cause of morbidity and mortality in Hong Kong. HNC is well-known for its heterogeneity in epidemiology, clinical behavior, clinic-pathological features and patient characteristics. Treatment strategies for t…
View article: The Efficacy of Triamcinolone Acetonide in Keloid Treatment: A Systematic Review and Meta-analysis
The Efficacy of Triamcinolone Acetonide in Keloid Treatment: A Systematic Review and Meta-analysis Open
Keloid is a cutaneous dermal outgrowth resulting from uncontrolled deposition of collagen and glycosaminoglycan around the wound. The uncontrolled and persistent growth of keloids scar will result in cosmetic disfigurement, functional impa…
View article: MicroRNA 744-3p promotes MMP-9-mediated metastasis by simultaneously suppressing PDCD4 and PTEN in laryngeal squamous cell carcinoma
MicroRNA 744-3p promotes MMP-9-mediated metastasis by simultaneously suppressing PDCD4 and PTEN in laryngeal squamous cell carcinoma Open
MicroRNA controls cancer invasion by governing the expression of gene regulating migration and invasion. Here, we reported a novel regulatory pathway controlled by miR-744-3p, which enhanced expression of matrix metallopeptidase 9 (MMP-9) …
View article: Decreased brain-expressed X-linked 4 (BEX4) expression promotes growth of oral squamous cell carcinoma
Decreased brain-expressed X-linked 4 (BEX4) expression promotes growth of oral squamous cell carcinoma Open
View article: Diagnostic Value of Methylated Human Telomerase Reverse Transcriptase in Human Cancers: A Meta-Analysis
Diagnostic Value of Methylated Human Telomerase Reverse Transcriptase in Human Cancers: A Meta-Analysis Open
Human telomerase reverse transcriptase (hTERT) plays a critical role in the pathogenesis of human malignancies. Overexpression of hTERT is essential in controlling the propagation of cancer cells. The CpG island located at hTERT promoter r…
View article: The role of Epstein‐Barr virus–encoded microRNA BART7 status of resection margins in the prediction of local recurrence after salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma
The role of Epstein‐Barr virus–encoded microRNA BART7 status of resection margins in the prediction of local recurrence after salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma Open
BACKGROUND Local recurrence is the major cause of treatment failure in patients who undergo surgical salvage of recurrent nasopharyngeal carcinoma (NPC) after radiotherapy. The authors investigated the role of Epstein‐Barr virus (EBV)‐enco…