Explanipedia

Nanopore detection of single-nucleotide RNA mutations and modifications with programmable nanolatches Open

Yunxuan Li, Shan Meng, Yesheng Wang, Casey M. Platnich, Max Earle , et al. · 2025

A Highly Efficient Chelating Agent Assisted the Synthesis of Prussian Blue as a Cathode Material for Sodium Ion Batteries Open

Yuhang Wang, Zanyu Sun, Jun Zhu, Feng Ye, Jinbo Zhu , et al. · 2025

Ionic Liquid-Chelated Prussian Blue Crystals for Sodium-Ion Batteries: Synthesis, Characterization, and Electrochemical Performance Open

Jiayi Fu, Yuhang Wang, Zanyu Sun, Jun Zhu, Jinbo Zhu , et al. · 2025

One pot RNA:DNA assembly for ribosomal RNA detection of pathogenic bacteria with single-molecule sensitivity Open

Filip Bošković, Sarah E. Sandler, Simon Brauburger, Yuan Shui, B. V. Vijaya Kumar , et al. · 2024

Effective treatment of infectious diseases hinges on timely and accurate diagnosis. Current methods face challenges in distinguishing between pathogens that cause a similar symptom and where appropriate treatment may be hindered by antimic…

Hybrid regularization inspired by total variation and deep denoiser prior for image restoration Open

Liang Hu, Jiahao Zhang, Daisen Wei, Jinbo Zhu · 2024

Image restoration is a fundamental problem in computer vision, with the goal of restoring high-quality images from degraded low-quality observation images. However, the ill-posedness of restoration problem often leads to artifacts in the r…

DNA Carrier-Assisted Molecular Ping-Pong in an Asymmetric Nanopore Open

Fei Zheng, Mohammed F. Alawami, Jinbo Zhu, Casey M. Platnich, Jingjie Sha , et al. · 2023

Nanopore analysis relies on ensemble averaging of translocation signals obtained from numerous molecules, requiring a relatively high sample concentration and a long turnaround time from the sample to results. The recapture and subsequent …

DNA Volume, Topology, and Flexibility Dictate Nanopore Current Signals Open

Yunxuan Li, Sarah E. Sandler, Ulrich F. Keyser, Jinbo Zhu · 2023

Nanopores have developed into powerful single-molecule sensors capable of identifying and characterizing small polymers, such as DNA, by electrophoretically driving them through a nanoscale pore and monitoring temporary blockades in the io…

Multiplexed Nanopore-Based Nucleic Acid Sensing and Bacterial Identification Using DNA Dumbbell Nanoswitches Open

Jinbo Zhu, Ran Tivony, Filip Bošković, Joana Pereira-Dias, Sarah E. Sandler , et al. · 2023

Multiplexed nucleic acid sensing methods with high specificity are vital for clinical diagnostics and infectious disease control, especially in the postpandemic era. Nanopore sensing techniques have developed in the past two decades, offer…

Simultaneous identification of viruses and viral variants with programmable DNA nanobait Open

Filip Bošković, Jinbo Zhu, Ran Tivony, Alexander Ohmann, Kaikai Chen , et al. · 2023

Damage Security Intelligent Identification of Wharf Concrete Structures under Deep Learning and Digital Image Technology Open

Jinbo Zhu, Yuesong Li, Pengrui Zhu · 2023

Artificial Intelligence (AI) technology has quickly developed under the mighty computing power of computers. At this stage, there are many mature non-destructive testing methods in civil engineering, but they are generally only suitable fo…

Influence of Temperature and Oxytetracycline Stress on Continuous Anaerobic Digestion: Methane Production, Antibiotic Resistance Genes Distribution and Microbial Response Open

Huiban He, Hongyang Xu, Haoxing He, Jinbo Zhu, Weiwei Wang , et al. · 2023

Long-Term Influence of Temperature and Oxytetracycline on Methane Production and Antibiotic Resistance Genes in Continuous Anaerobic Digestion Open

Huiban He, Hongyang Xu, Haoxing He, Jinbo Zhu, Weiwei Wang , et al. · 2023

DNA-Based Optical Quantification of Ion Transport across Giant Vesicles Open

Marcus Fletcher, Jinbo Zhu, Roger Rubio‐Sánchez, Sarah E. Sandler, Kareem Al Nahas , et al. · 2022

Accurate measurements of ion permeability through cellular membranes remains challenging due to the lack of suitable ion-selective probes. Here we use giant unilamellar vesicles (GUVs) as membrane models for the direct visualization of mas…

Split G-Quadruplexes Enhance Nanopore Signals for Simultaneous Identification of Multiple Nucleic Acids Open

Jinbo Zhu, Filip Bošković, Ulrich F. Keyser · 2022

Assembly of DNA structures based on hybridization like split G-quadruplex (GQ) have great potential for the base-pair specific identification of nucleic acid targets. Herein, we combine multiple split G-quadruplex (GQ) assemblies on design…

Lifetime of glass nanopores in a PDMS chip for single-molecule sensing Open

Mohammed F. Alawami, Filip Bošković, Jinbo Zhu, Kaikai Chen, Sarah E. Sandler , et al. · 2022

Parallel DNA circuits by autocatalytic strand displacement and nanopore readout Open

Jinbo Zhu, Jinglin Kong, Ulrich F. Keyser, Erkang Wang · 2022

Parallel DNA circuits are constructed using autocatalytic strand displacement reactions and measured using a nanopore multiplexed sensing platform.

Simultaneous identification of viruses and viral variants with programmable DNA nanobait Open

Filip Bošković, Jinbo Zhu, Ran Tivony, Alexander Ohmann, Kaikai Chen , et al. · 2021

Respiratory infections are the major cause of death from infectious disease worldwide. Multiplexed diagnostic approaches are essential as many respiratory viruses have indistinguishable symptoms. We created self-assembled DNA nanobait that…

FeII4L4 tetrahedron binds and aggregates DNA G-quadruplexes Open

Jinbo Zhu, Zhiqiang Yan, Filip Bošković, Cally J. E. Haynes, Marion Kieffer , et al. · 2021

Since the discovery of the G-quadruplex (G4) structure in telomeres in 1980s, studies have established the role it plays in various biological processes. Here we report binding between DNA G4 and a self-assembled tetrahedral metal-organic …

DNA breathing initiated strand displacement circuits for mimicking ant foraging with nanopore readout Open

Jinbo Zhu, Jinglin Kong, Ulrich F. Keyser, Erkang Wang · 2021

DNA strand displacement reaction is essential for the development of molecular computing based on DNA nanotechnology. Additional DNA strand exchange strategies with high selectivity for input will enable novel complex systems including bio…

DNA breathing initiated DNA parallel circuits with nanopore readout Open

Jinbo Zhu, Jinglin Kong, Ulrich F. Keyser, Erkang Wang · 2021

Fluorescence and nanopore current data are provided here accompanying the publication.

DNA breathing initiated DNA parallel circuits with nanopore readout Open

Jinbo Zhu, Jinglin Kong, Ulrich F. Keyser, Erkang Wang · 2021

Fluorescence and nanopore current data are provided here accompanying the publication.

Image Encoding Using Multi‐Level DNA Barcodes with Nanopore Readout Open

Jinbo Zhu, Niklas Ermann, Kaikai Chen, Ulrich F. Keyser · 2021

Deoxyribonucleic acid (DNA) nanostructure‐based data encoding is an emerging information storage mode, offering rewritable, editable, and secure data storage. Herein, a DNA nanostructure‐based storage method established on a solid‐state na…

CCDC 1890517: Experimental Crystal Structure Determination Open

Alex J. Plajer, Jinbo Zhu, Patrick Proehm, Andrew D. Bond, Ulrich F. Keyser , et al. · 2021

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1890516: Experimental Crystal Structure Determination Open

Alex J. Plajer, Jinbo Zhu, Patrick Proehm, Andrew D. Bond, Ulrich F. Keyser , et al. · 2021

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1890522: Experimental Crystal Structure Determination Open

Alex J. Plajer, Jinbo Zhu, Patrick Proehm, Andrew D. Bond, Ulrich F. Keyser , et al. · 2021

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1890521: Experimental Crystal Structure Determination Open

Alex J. Plajer, Jinbo Zhu, Patrick Proehm, Andrew D. Bond, Ulrich F. Keyser , et al. · 2021

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Kinetics of Toehold-Mediated DNA Strand Displacement Depend on FeII4L4 Tetrahedron Concentration Open

Jinbo Zhu, Filip Bošković, Bao‐Nguyen T. Nguyen, Jonathan R. Nitschke, Ulrich F. Keyser · 2021

The toehold-mediated strand displacement reaction (SDR) is a powerful enzyme-free tool for molecular manipulation, DNA computing, signal amplification, etc. However, precise modulation of SDR kinetics without changing the original design r…

Storage and Cleaning Extend Lifetime of Glass Nanopores for Biosensing Open

Mohammed F. Alawami, Filip Bošković, Jinbo Zhu, Kaikai Chen, Sarah E. Sandler , et al. · 2021

FeII4L4 tetrahedron binds and aggregates DNA G-quadruplexes Open

Jinbo Zhu, Zhiqiang Yan, Filip Bošković, Cally J. E. Haynes, Marion Kieffer , et al. · 2021

We find FeII4L 4 binds to G-quadruplex and forms aggregates. G-quadruplex in the aggregates is protected from digestion by S 1 nuclease.

Nanopore-Based DNA Hard Drives for Rewritable and Secure Data Storage Open

Kaikai Chen, Jinbo Zhu, Filip Bošković, Ulrich F. Keyser · 2020

Nanopores are powerful single-molecule tools for label-free sensing of nanoscale molecules including DNA that can be used for building designed nanostructures and performing computations. Here, DNA hard drives (DNA-HDs) are introduced base…

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