Jian Du
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View article: Multicenter epidemiological investigation and analysis of factors associated with transient synovitis of the hip in 5065 children treated across 32 tertiary children’s hospitals in China
Multicenter epidemiological investigation and analysis of factors associated with transient synovitis of the hip in 5065 children treated across 32 tertiary children’s hospitals in China Open
View article: The emerging role of miR-22 in inflammation
The emerging role of miR-22 in inflammation Open
MicroRNA-22 (miR-22), discovered in 2007, is a small non-coding RNA comprising 22 nucleotides. It is widely expressed in organisms and conserved across different species. A series of studies have shown that miR-22 not only regulates the gr…
View article: GWO-elman based composite detection of transformer oil flow temperature
GWO-elman based composite detection of transformer oil flow temperature Open
View article: Association Between Influenza Vaccine and Immune Thrombocytopenia: A Systematic Review and Meta-Analysis
Association Between Influenza Vaccine and Immune Thrombocytopenia: A Systematic Review and Meta-Analysis Open
Background: Immune thrombocytopenia (ITP) is an uncommon but serious adverse reaction after vaccination. However, its association with vaccines other than the measles–mumps–rubella vaccine remains debatable. This study aimed to analyze ITP…
View article: Multicenter epidemiological analysis of related factors in 10,808 hospitalized children with lower limb and pelvic fractures in China
Multicenter epidemiological analysis of related factors in 10,808 hospitalized children with lower limb and pelvic fractures in China Open
View article: Rubella antibody levels in the healthy Chinese population: a meta-analysis
Rubella antibody levels in the healthy Chinese population: a meta-analysis Open
Objectives To gain a comprehensive understanding of rubella seroprevalence in the healthy population in China and to offer data-driven support for the goal of rubella elimination. Methods CNKI, Wanfang database, VIP database, CBM, PubMed, …
View article: Association between influenza vaccine and immune thrombocytopenia
Association between influenza vaccine and immune thrombocytopenia Open
View article: Analysis of Adverse Events Post-13-Valent Pneumococcal Vaccination among Children in Hangzhou, China
Analysis of Adverse Events Post-13-Valent Pneumococcal Vaccination among Children in Hangzhou, China Open
With the widespread use of the 13-valent pneumonia vaccine (PCV13) in China, monitoring adverse events following immunization (AEFIs) is critical. We conducted a descriptive analysis of the AEFI occurrences reported within Hangzhou between…
View article: The health economics evaluation of HPV vaccine with different immunization strategies in Zhejiang Province based on the PRIME tool
The health economics evaluation of HPV vaccine with different immunization strategies in Zhejiang Province based on the PRIME tool Open
Objective: To evaluate the health economics of human papillomavirus (HPV) vaccination for school-age female children in Zhejiang Province under different immunization regimens. Methods: The PRIME tool recommended by the World Health Organi…
View article: Rubella antibody levels in the healthy Chinese population:a meta-analysis
Rubella antibody levels in the healthy Chinese population:a meta-analysis Open
Objectives To gain a comprehensive understanding of rubella antibody levels in the healthy population in China and to offer data-driven support for the goal of rubella elimination. Methods CNKI, Wanfang database, VIP database, CBM, PubMed,…
View article: Jiedu Xiaozheng Yin Extract Targets Cancer Stem Cells by Wnt Signaling Pathway in Colorectal Cancer
Jiedu Xiaozheng Yin Extract Targets Cancer Stem Cells by Wnt Signaling Pathway in Colorectal Cancer Open
View article: NUP85 alleviates lipid metabolism and inflammation by regulating PI3K/AKT signaling pathway in nonalcoholic fatty liver disease
NUP85 alleviates lipid metabolism and inflammation by regulating PI3K/AKT signaling pathway in nonalcoholic fatty liver disease Open
Nonalcoholic fatty liver disease (NAFLD) is one of the common causes of chronic liver disease in the world. The problem of NAFLD had become increasingly prominent. However, its pathogenesis is still indistinct. As we all know, NAFLD begins…
View article: Acceptance of influenza vaccination and associated factors among teachers in China: A cross-sectional study based on health belief model
Acceptance of influenza vaccination and associated factors among teachers in China: A cross-sectional study based on health belief model Open
Teachers played an important role on the transmission of influenza in schools and communities. The study aims to investigate the influenza vaccination coverage and the factors determining flu vaccination acceptance among teachers in Hangzh…
View article: Do adolescents need a rubella vaccination campaign? Rubella serosurvey among healthy children in Hangzhou, China
Do adolescents need a rubella vaccination campaign? Rubella serosurvey among healthy children in Hangzhou, China Open
The aim of this study was to evaluate the seroprevalence of rubella antibodies and factors associated with antibody seropositivity after vaccination among healthy children aged 14 and below. A multi-stage stratified random sampling method …
View article: Analysis of 13-valent pneumococcal polysaccharide conjugate vaccine among children born in Hangzhou from 2017 to 2021
Analysis of 13-valent pneumococcal polysaccharide conjugate vaccine among children born in Hangzhou from 2017 to 2021 Open
Background 13-valent pneumococcal polysaccharide conjugate vaccine (PCV13) has been introduced in Hangzhou since 2017, whereas its current immunization state in children is not clear. Therefore, this study aims to describe the PCV13 vaccin…
View article: Studies on the mechanism of Toxoplasma gondii Chinese 1 genotype Wh6 strain causing mice abnormal cognitive behavior
Studies on the mechanism of Toxoplasma gondii Chinese 1 genotype Wh6 strain causing mice abnormal cognitive behavior Open
View article: Protection Against Diphtheria in Hangzhou, China after Over 40 Years of Vaccination: Results from a Seroepidemiological Study
Protection Against Diphtheria in Hangzhou, China after Over 40 Years of Vaccination: Results from a Seroepidemiological Study Open
View article: Impact of Toxoplasmosis on domestic animal production and its significance in the risk of human infection in China
Impact of Toxoplasmosis on domestic animal production and its significance in the risk of human infection in China Open
Toxoplasma gondii is a ubiquitous zoonotic food-borne parasite [1]. Nearly one-third of the world’s population has been exposed to the parasite, with prevalence ranging from ~10% to 50% depending on the geographical area. Human infection i…
View article: Cost-effectiveness of various immunization schedules with inactivated Sabin strain polio vaccine in Hangzhou, China
Cost-effectiveness of various immunization schedules with inactivated Sabin strain polio vaccine in Hangzhou, China Open
Background It is necessary to select suitable inactivated poliovirus vaccine(IPV) and live, attenuated oral poliovirus vaccine (OPV) sequential immunization programs and configure the corresponding health resources. An economic evaluation …
View article: Application and progress of the detection technologies in hepatocellular carcinoma
Application and progress of the detection technologies in hepatocellular carcinoma Open
Hepatocellular carcinoma (HCC) has a very high incidence and fatality rate, and in most cases, it is already at an advanced stage when diagnosed. Therefore, early prevention and detection of HCC are two of the most effective strategies. Ho…
View article: Epidemiological characteristic of rubella by age group during 12 years after the national introduction of rubella vaccine in Hangzhou, China
Epidemiological characteristic of rubella by age group during 12 years after the national introduction of rubella vaccine in Hangzhou, China Open
This study aimed to evaluate the implementation and impact of rubella-containing vaccine (RCV) by describing the rubella epidemiology and seroepidemiology in Hangzhou. We collected rubella cases of Hangzhou in the Information System for Di…
View article: Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis Open
Liver ischemia/reperfusion (I/R) injury is a primary complication in major liver surgery. Our previous study about proteome profiling has revealed that the PPAR signaling cascade was significantly upregulated during liver ischemia/reperfus…
View article: Cancer associated fibroblasts (CAFs) derived exosomes with A promoted liver metastasis of pancreatic cancer by regulating C through transcription factor B
Cancer associated fibroblasts (CAFs) derived exosomes with A promoted liver metastasis of pancreatic cancer by regulating C through transcription factor B Open
Cancer-associated fibroblasts (CAFs) comprise the majority of the tumor bulk of pancreatic ductal adenocarcinomas (PDACs). Despite the long-standing recognition of the prominence of CAFs in PDAC, the effect of extracellular vesicles derive…
View article: Hepatitis B virus infection seromarkers among college freshmen and their immune responses to different vaccination policies of hepatitis B vaccine
Hepatitis B virus infection seromarkers among college freshmen and their immune responses to different vaccination policies of hepatitis B vaccine Open
The HBsAg carrying rate and anti-HBs positive rate of college freshmen were low, and the HepB has a good effect on the immunity of college freshmen. Increasing the immunization rate of HepB is very important for the prevention and control …
View article: Safety and efficacy of S1 monotherapy or combined with nab-paclitaxel in advanced elderly pancreatic cancer patients
Safety and efficacy of S1 monotherapy or combined with nab-paclitaxel in advanced elderly pancreatic cancer patients Open
Objective: To evaluate the therapeutic efficacy and safety of S1 monotherapy or combination with nab-paclitaxel for the treatment of elderly patients with metastatic or locally advanced pancreatic adenocarcinoma. Method: PubMed, Embase, Co…
View article: [Inhibiting autophagy by silencing ATG5 and ATG7 enhances inhibitory effect of DDP on DDP-resistant I-10 testicular cancer cells].
[Inhibiting autophagy by silencing ATG5 and ATG7 enhances inhibitory effect of DDP on DDP-resistant I-10 testicular cancer cells]. Open
Silencing ATG5 and ATG7 inhibits cisplatin-mediated autophagy and enhances the inhibitory effect of cisplatin on inhibiting cell proliferation.
View article: RNF2 Mediates Hepatic Stellate Cells Activation by Regulating ERK/p38 Signaling Pathway in LX-2 Cells
RNF2 Mediates Hepatic Stellate Cells Activation by Regulating ERK/p38 Signaling Pathway in LX-2 Cells Open
The therapeutic approach of liver fibrosis is still an unsolved clinical problem worldwide. Notably, the accumulation of extracellular matrix (ECM) in the liver is mediated by the production of cytokines and growth factors, such as transfo…
View article: Correction for: LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA
Correction for: LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA Open
View article: Epidemiology and association rules analysis for pulmonary tuberculosis cases with extrapulmonary tuberculosis from age and gender perspective: a large-scale multi-center observational study in China
Epidemiology and association rules analysis for pulmonary tuberculosis cases with extrapulmonary tuberculosis from age and gender perspective: a large-scale multi-center observational study in China Open
Background Tuberculosis (TB), a multi-systemic disease with protean presentation, remains a major global health problem. Although concurrent pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) cases are commonly observed cl…
View article: Global proteome profiling of human livers upon ischemia/reperfusion treatment
Global proteome profiling of human livers upon ischemia/reperfusion treatment Open