Jin Xu
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View article: Burden of common infectious diseases in children with growth failure from 1990 to 2021: analysis of the Global Burden of Disease Study
Burden of common infectious diseases in children with growth failure from 1990 to 2021: analysis of the Global Burden of Disease Study Open
Background Child undernutrition is a serious public health problem that is associated with various infectious diseases (diarrheal diseases, malaria, measles, respiratory infections and tuberculosis). However, an assessment of the global bu…
View article: Blood neurofilament light chain as a predictive biomarker for functional outcome of acute ischemic stroke: a systematic review and meta-analysis
Blood neurofilament light chain as a predictive biomarker for functional outcome of acute ischemic stroke: a systematic review and meta-analysis Open
Aim: Ischemic stroke continues to be a significant contributor to mortality and disability on a global scale. The blood neurofilament light chain (bNfL) as a prognostic indicator for stroke functional outcomes is a topic of ongoing debate.…
View article: [Prognostic value of the FS-15 frailty score in patients with myelodysplastic syndromes].
[Prognostic value of the FS-15 frailty score in patients with myelodysplastic syndromes]. Open
Objective: To identify the prognostic value of the Revised 15-item Myelodysplastic Syndrome-specific frailty scale (FS-15) in Chinese patients with myelodysplastic syndromes (MDS) . Methods: This retrospective study analyzed …
View article: The optimal childbearing age and birth spacing in china: a multicenter retrospective cohort study
The optimal childbearing age and birth spacing in china: a multicenter retrospective cohort study Open
View article: Letter to the editor regarding “Fractal analysis based on Gd-EOB-DTPA-enhanced MRI for prediction of vessels that encapsulate tumor clusters in patients with hepatocellular carcinoma.”
Letter to the editor regarding “Fractal analysis based on Gd-EOB-DTPA-enhanced MRI for prediction of vessels that encapsulate tumor clusters in patients with hepatocellular carcinoma.” Open
View article: Differential risk and clinical characteristics of placenta accreta spectrum in twin and singleton pregnancies: implications for perinatal outcomes
Differential risk and clinical characteristics of placenta accreta spectrum in twin and singleton pregnancies: implications for perinatal outcomes Open
Twin gestation, regardless of known risk factors, increases the risk of placenta accreta and adverse perinatal outcomes compared to singleton pregnancies. Antenatal interventions and delivery risk management are essential for twin pregnanc…
View article: Oxidative Balance Score and Osteoarthritis: A Multi-Omics Study Based on NHANES, RNA-seq, and Mendelian Randomization
Oxidative Balance Score and Osteoarthritis: A Multi-Omics Study Based on NHANES, RNA-seq, and Mendelian Randomization Open
This study employs a multi-omics approach to investigate the association between the Oxidative Balance Score (OBS) and Osteoarthritis (OA), aiming to uncover molecular mechanisms and identify therapeutic targets. Analyzing baseline charact…
View article: Obstructive sleep apnea-associated hypertensive disorders in pregnancy: a literature review and clinical management strategies
Obstructive sleep apnea-associated hypertensive disorders in pregnancy: a literature review and clinical management strategies Open
View article: The trajectory of frailty index and its association with rapid decline in kidney function and the incidence of chronic kidney disease: evidence from the China health and retirement longitudinal study
The trajectory of frailty index and its association with rapid decline in kidney function and the incidence of chronic kidney disease: evidence from the China health and retirement longitudinal study Open
A higher FI trajectory is associated with an increased risk of rapid decline in kidney function. The findings underscore the critical importance of monitoring the dynamic changes in frailty among middle-aged and older adults.
View article: Comparative clinical outcomes of surgical versus conservative treatment for multiple rib fractures: A retrospective analysis
Comparative clinical outcomes of surgical versus conservative treatment for multiple rib fractures: A retrospective analysis Open
This study explores the clinical effects of surgical treating and conservative treating for multiple rib fractures (MRF). The study selected patients with MRF admitted to the thoracic surgery and emergency department of our hospital from 2…
View article: Construction of Maoist Cultural Heritage Corridor in Pingxiang City Based on MCR Model
Construction of Maoist Cultural Heritage Corridor in Pingxiang City Based on MCR Model Open
Heritage corridor, as a comprehensive regional heritage preservation method, has gradually become a crucial tool for enhancing the value of heritage utilization and promoting tourism development. However, there is currently a lack of resea…
View article: Impact of antenatal corticosteroid therapy on neonatal outcomes in twin pregnancies
Impact of antenatal corticosteroid therapy on neonatal outcomes in twin pregnancies Open
Antenatal corticosteroids, whether in early or late preterm births, may not prevent NRDS and respiratory composite outcomes in twin neonates, but they are effective in reducing adverse neonatal outcomes such as pneumonia, low birth weight,…
View article: Associations between meteorological factors and pregnancy complications during different pregnancy trimesters: a multicenter retrospective study in eastern China
Associations between meteorological factors and pregnancy complications during different pregnancy trimesters: a multicenter retrospective study in eastern China Open
Background Previous studies have demonstrated the effects of ambient temperature on the risk of pregnancy complications. However, the associations between multiple meteorological factors and pregnancy complications have rarely been studied…
View article: Steroid Sulfatase Regulates Metabolic Reprogramming in Advanced Prostate Cancer
Steroid Sulfatase Regulates Metabolic Reprogramming in Advanced Prostate Cancer Open
Background/Objective: The expression of human steroid sulfatase (STS) is upregulated in castration-resistant prostate cancer (CRPC) and is associated with resistance to anti-androgen drugs, such as enzalutamide (Enza) and abiraterone (Abi)…
View article: The global burden of polycystic ovary syndrome, endometriosis, uterine fibroids, cervical cancer, uterine cancer, and ovarian cancer from 1990 to 2021
The global burden of polycystic ovary syndrome, endometriosis, uterine fibroids, cervical cancer, uterine cancer, and ovarian cancer from 1990 to 2021 Open
View article: The association between the cardiac metabolic index and rapid kidney function decline and CKD in individuals with different glucose metabolism statuses: results from the China health and retirement longitudinal study
The association between the cardiac metabolic index and rapid kidney function decline and CKD in individuals with different glucose metabolism statuses: results from the China health and retirement longitudinal study Open
View article: The Evolution of Ischemia‐Reperfusion Injury Research in Ischemic Stroke: Insights From a Two‐Decade Bibliometric Analysis
The Evolution of Ischemia‐Reperfusion Injury Research in Ischemic Stroke: Insights From a Two‐Decade Bibliometric Analysis Open
Background Ischemic stroke is a complex disease with high mortality and disability rates. Ischemia‐reperfusion injury is a common aftermath. There have been significant advancements in understanding ischemia‐reperfusion injury in ischemic …
View article: [Familial erythrocytosis type 2 due to VHL germline mutations: a case report and literature review].
[Familial erythrocytosis type 2 due to VHL germline mutations: a case report and literature review]. Open
To enhance the understanding of familial erythrocytosis type 2 (ECYT2) resulting from compound heterozygous mutations in the VHL gene. Methods: We conducted a retrospective analysis of the case data from a patient with ECYT2 to inve…
View article: Sleep features and the risk of type 2 diabetes mellitus: a systematic review and meta-analysis
Sleep features and the risk of type 2 diabetes mellitus: a systematic review and meta-analysis Open
A U-shaped relationship was observed between sleep duration and type 2 diabetes mellitus (T2DM), with the lowest risk occurring at a sleep duration of 7 to 8 h. Additionally, poor sleep quality, evening chronotypes, and daytime napping exc…
View article: The Impact of the First Trimester and Second Trimester Temperature, Air Pollutants, and Seasonal Variations on the Risk of Gestational Diabetes Mellitus in Twin Pregnancies
The Impact of the First Trimester and Second Trimester Temperature, Air Pollutants, and Seasonal Variations on the Risk of Gestational Diabetes Mellitus in Twin Pregnancies Open
Background: Recent studies have primarily focused on the impact of environmental factors on gestational diabetes mellitus (GDM) in singleton pregnancies, with limited research on their effects in twin pregnancies. This study investigates h…
View article: Neoadjuvant adebrelimab combined with chemotherapy (cisplatin/carboplatin and etoposide) for limited-stage small-cell lung cancer: a study protocol of phase 2 trial (NIUS)
Neoadjuvant adebrelimab combined with chemotherapy (cisplatin/carboplatin and etoposide) for limited-stage small-cell lung cancer: a study protocol of phase 2 trial (NIUS) Open
Introduction Small-cell lung cancer (SCLC) is a highly malignant neuroendocrine tumour, and concurrent chemoradiotherapy is the current recommended treatment for limited-stage SCLC. However, the overall survival (OS) of patients with SCLC …
View article: Evaluation On Five-Dimensions Of A Patient Counseling MHealth App In Ambulatory Care Pharmacy: A Cross-Sectional Study On Pediatric Caregiver’s Opinion
Evaluation On Five-Dimensions Of A Patient Counseling MHealth App In Ambulatory Care Pharmacy: A Cross-Sectional Study On Pediatric Caregiver’s Opinion Open
To improve a pediatric mHealth app for patient counselling, we developed a multi-dimensional evaluation method assessing caregivers' feedback via a cross-sectional survey. Using random questionnaires at a children's hospital outpatient dep…
View article: Robust Uav Power Line Detection Using Transformer-Based Reinforcement Learning in Gps-Denied and Wind Disturbances Environments
Robust Uav Power Line Detection Using Transformer-Based Reinforcement Learning in Gps-Denied and Wind Disturbances Environments Open
View article: Immunoengineering Approaches for Cancer Immunotherapy and Autoimmune Diseases
Immunoengineering Approaches for Cancer Immunotherapy and Autoimmune Diseases Open
Immunotherapy, which leverages the host immune system to combat diseases, has thrived in addressing numerous intractable conditions, including cancer, autoimmune disorders, infectious diseases, and allergies. Despite its breakthroughs, sig…
View article: Genetically predicted immune cells mediate the association between gut microbiota and autoimmune liver diseases
Genetically predicted immune cells mediate the association between gut microbiota and autoimmune liver diseases Open
Background Increasing evidence suggests an association between gut microbiota and Autoimmune Liver Diseases (AILDs). However, causal inference remains controversial due to confounding bias in observational studies. Additionally, there is c…
View article: Identification of hsa_circ_0076957 and miR-4512-targeted COL19A1 as regulators in clopidogrel resistance among stable coronary heart disease patients through comprehensive circRNA and miRNA analysis
Identification of hsa_circ_0076957 and miR-4512-targeted COL19A1 as regulators in clopidogrel resistance among stable coronary heart disease patients through comprehensive circRNA and miRNA analysis Open
These findings highlight hsa_circ_0057714 and hsa_circ_0076957 as novel biomarkers for CR and suggest that circ-0076957 may regulate COL19A1 expression by targeting miR-4512, providing insights that could improve management of clopidogrel …
View article: Spatiotemporal trends of Type 2 diabetes due to low physical activity from 1990 to 2019 and forecasted prevalence in 2050: A Global Burden of Disease Study 2019
Spatiotemporal trends of Type 2 diabetes due to low physical activity from 1990 to 2019 and forecasted prevalence in 2050: A Global Burden of Disease Study 2019 Open
LPA significantly impacts T2DM, particularly in low SDI regions. Promotion of physical activity is crucial to reduce this burden, particularly in regions where the disease's impact is most severe.
View article: Machine-learning-based prediction by stacking ensemble strategy for surgical outcomes in patients with degenerative cervical myelopathy
Machine-learning-based prediction by stacking ensemble strategy for surgical outcomes in patients with degenerative cervical myelopathy Open
The ensemble classifiers successfully predict the JOA recovery rate in DCM patients, which showed a high potential for assisting physicians in managing DCM patients and making full use of medical resources.
View article: Evaluation of the Role of Endomyocardial Biopsy in Rare Myocardial Disorders: Six Case Reports and Narratives
Evaluation of the Role of Endomyocardial Biopsy in Rare Myocardial Disorders: Six Case Reports and Narratives Open
This study conducts an observational analysis of 6 cases of rare myocardial diseases, aiming to clarify the diagnostic value and clinical utility of endomyocardial biopsy (EMB) in the 2007 American Heart Association, American College of Ca…
View article: Tislelizumab for treatment of a pediatric patient with primary mediastinal choriocarcinoma: a case report
Tislelizumab for treatment of a pediatric patient with primary mediastinal choriocarcinoma: a case report Open
The effectiveness of chemotherapy for PCC is limited. Tislelizumab may potentially serve as salvage treatment options for PCC.