Jin‐Ah Lee
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View article: Mesenchymal stem cells with an enhanced antioxidant capacity integrate as smooth muscle cells in a model of diabetic detrusor underactivity
Mesenchymal stem cells with an enhanced antioxidant capacity integrate as smooth muscle cells in a model of diabetic detrusor underactivity Open
View article: Lindera obtusiloba Blume Alleviates Non-Alcoholic Fatty Liver Disease Promoted by Nε-(carboxymethyl)lysine
Lindera obtusiloba Blume Alleviates Non-Alcoholic Fatty Liver Disease Promoted by Nε-(carboxymethyl)lysine Open
Non-alcoholic fatty liver disease (NAFLD) is a major issue because it is closely associated with metabolic diseases. Advanced glycation end products (AGEs) are implicated as risk factors for steatosis during NAFLD progression. AGEs influen…
View article: Chronic Social Defeat Stress Gives Rise to Social Avoidance Through Fear Learning
Chronic Social Defeat Stress Gives Rise to Social Avoidance Through Fear Learning Open
Chronic social defeat stress (CSDS), a widely used rodent model of stress, reliably leads to decreased social interaction in stress susceptible animals. Here, we investigate a role for fear learning in this response using 129Sv/Ev mice, a …
View article: Discovery of (−)-epigallocatechin gallate, a novel olfactory receptor 2AT4 agonist that regulates proliferation and apoptosis in leukemia cells
Discovery of (−)-epigallocatechin gallate, a novel olfactory receptor 2AT4 agonist that regulates proliferation and apoptosis in leukemia cells Open
View article: Cases and Implications of Residences for Elderly People with Service in Japan
Cases and Implications of Residences for Elderly People with Service in Japan Open
서비스 제공 고령자 주택은 생활지원 서비스가 지원되는 주택으로 고령자가 안심하고 생활할 수 있는 주거 만들기를 위해 제정된 것이다. 본 연구는 일본에서 실시하고 있는 서비스 제공 고령자 주택 현황 및 사례 등을 살펴보고 우리나라 고령자 주택에 대한 시사점을 알아보는 것이다. 이러한 목적을 달성하기 위해 일본의 후생노동성, 국토교통부 등에서 발간한 보고서 및 관련자료 그리고 학계 논문 등의 문헌을 중심으로 살펴보았다. 일본의 …
View article: Stimuli-Responsive Biodegradable Soft Gripper Composed of Ph-Responsive Alginate/Gelatin/Acrylic Acid and Non-Ph-Responsive Acrylamide Bilayer
Stimuli-Responsive Biodegradable Soft Gripper Composed of Ph-Responsive Alginate/Gelatin/Acrylic Acid and Non-Ph-Responsive Acrylamide Bilayer Open
View article: Engineering of Cell Derived-Nanovesicle as an Alternative to Exosome Therapy
Engineering of Cell Derived-Nanovesicle as an Alternative to Exosome Therapy Open
View article: Glutathione dynamics is a potential predictive and therapeutic trait for neoadjuvant chemotherapy response in bladder cancer
Glutathione dynamics is a potential predictive and therapeutic trait for neoadjuvant chemotherapy response in bladder cancer Open
View article: Effect of surface matching mismatch of focal knee articular prosthetic on tibiofemoral contact stress using finite element analysis
Effect of surface matching mismatch of focal knee articular prosthetic on tibiofemoral contact stress using finite element analysis Open
Aims Focal knee arthroplasty is an attractive alternative to knee arthroplasty for young patients because it allows preservation of a large amount of bone for potential revisions. However, the mechanical behaviour of cartilage has not yet …
View article: Exploring Australia’s Carer Support -Focused on Family Carers Taking Care of the Elderly-
Exploring Australia’s Carer Support -Focused on Family Carers Taking Care of the Elderly- Open
본 연구는 호주에서 시행하고 있는 돌봄자, 특히 노인을 돌보는 가족돌봄자에 대한 지원 관련 시책 및 서비스 내용을 중심으로 관련 자료 등을 문헌조사를 통해 살펴보았다. 그리고 이를 바탕으로 우리나라 노인을 돌보는 가족돌봄자 지원에 대한 시사점을 찾고자 하는 목적을 가진다. 우리나라와 다른 호주의 특징 중 하나는 돌봄자들의 사회적, 경제적 공헌을 공식적으로 인정하는 “돌봄자인정법”이 2010년 제정되었다는 점이다. 또한 가족의…
View article: Exploring Competencies for Interprofessional Collaboration in Health, Medical, and Welfare Fields -Focused on America, Canada, and Japan-
Exploring Competencies for Interprofessional Collaboration in Health, Medical, and Welfare Fields -Focused on America, Canada, and Japan- Open
복합적인 욕구를 지닌 클라이언트가 증가하는 상황 속에서 이들의 욕구를 충족하고 적절한 서비스를 제공하기 위해서는 보건·의료·복지 등의 분야에서의 협력적 접근 및 다직종 연계에 대한 노력이 요구된다. 이러한 다직종 연계를 위해서는 협력적 실천 및 교육적 개입 개발과 실행에 있어서 요구되는 핵심적 역량 파악이 매우 중요하다. 이러한 점에 기반하여 본 연구에서는 다직종 연계 및 연계 역량과 관련한 내용을 미국, 캐나다, 일본을 중…
View article: Computational analysis of tibial slope adjustment with fixed-bearing medial unicompartmental knee arthroplasty in ACL- and PCL-deficient models
Computational analysis of tibial slope adjustment with fixed-bearing medial unicompartmental knee arthroplasty in ACL- and PCL-deficient models Open
Aims A functional anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL) has been assumed to be required for patients undergoing unicompartmental knee arthroplasty (UKA). However, this assumption has not been thoroughly test…
View article: Exploring Factors and Countermeasures Related to Abusers of the Elderly in Korea and Japan
Exploring Factors and Countermeasures Related to Abusers of the Elderly in Korea and Japan Open
본 연구의 목적은 한국과 일본의 노인학대 행위자의 학대 행위 관련 요인 및 이들에 대한 법률적 대응 내용을 탐색하고, 이를 기반으로 우리나라의 노인학대 예방 및 학대 재발 방지를 위한 방안을 모색하는 것이다. 이러한 목적을 달성하기 위한 연구 방법으로 두 나라의 노인학대행위자 관련 문헌 및 법률의 내용을 비교 분석하였다. 연구 결과 한국의 경우 학대 행위자에 대한 대응에 있어서 정보 및 상담제공 수준에 머무르고 있으며 노인보…
View article: Retraction Note: Effect of sagittal femoral component alignment on biomechanics after mobile-bearing total knee arthroplasty
Retraction Note: Effect of sagittal femoral component alignment on biomechanics after mobile-bearing total knee arthroplasty Open
View article: Skin Brightening Efficacy of Exosomes Derived from Human Adipose Tissue-Derived Stem/Stromal Cells: A Prospective, Split-Face, Randomized Placebo-Controlled Study
Skin Brightening Efficacy of Exosomes Derived from Human Adipose Tissue-Derived Stem/Stromal Cells: A Prospective, Split-Face, Randomized Placebo-Controlled Study Open
Studies have shown that stem cells and their derivatives, including conditioned media (CM), have inhibitory effects on skin pigmentation. However, evidence supporting the skin brightening effect of exosomes derived from stem cells is lacki…
View article: Effects of contact stress on patellarfemoral joint and quadriceps force in fixed and mobile-bearing medial unicompartmental knee arthroplasty
Effects of contact stress on patellarfemoral joint and quadriceps force in fixed and mobile-bearing medial unicompartmental knee arthroplasty Open
Background Unicompartmental knee arthroplasty (UKA) is an effective treatment for end-stage, symptomatic unicompartmental osteoarthritis of the knee joint. However, patellofemoral joint degeneration is a contraindication to medial UKA. The…
View article: Effects of contact stress on patellarfemoral joint and quadriceps force in fixed and mobile-bearing medial unicompartmental knee arthroplasty
Effects of contact stress on patellarfemoral joint and quadriceps force in fixed and mobile-bearing medial unicompartmental knee arthroplasty Open
Background Unicompartmental knee arthroplasty (UKA) is an effective treatment for end-stage, symptomatic unicompartmental osteoarthritis of the knee joint. However, patellofemoral joint degeneration is a contraindication to medial UKA. The…
View article: Effects of contact stress on patellarfemoral joint and quadriceps force in fixed and mobile-bearing medial unicompartmental knee arthroplasty
Effects of contact stress on patellarfemoral joint and quadriceps force in fixed and mobile-bearing medial unicompartmental knee arthroplasty Open
Background Unicompartmental knee arthroplasty (UKA) is an effective treatment for end-stage, symptomatic unicompartmental osteoarthritis of the knee joint. However, patellofemoral joint degeneration is a contraindication to medial UKA. The…
View article: Biomechanical effect of tibial slope on the stability of medial unicompartmental knee arthroplasty in posterior cruciate ligament-deficient knees
Biomechanical effect of tibial slope on the stability of medial unicompartmental knee arthroplasty in posterior cruciate ligament-deficient knees Open
Aims Unicompartmental knee arthroplasty (UKA) has become a popular method of treating knee localized osteoarthritis (OA). Additionally, the posterior cruciate ligament (PCL) is essential to maintaining the physiological kinematics and func…
View article: Restoration of normal knee kinematics with respect to tibial insert design in mobile bearing lateral unicompartmental arthroplasty using computational simulation
Restoration of normal knee kinematics with respect to tibial insert design in mobile bearing lateral unicompartmental arthroplasty using computational simulation Open
Aims Mobile-bearing unicompartmental knee arthroplasty (UKA) with a flat tibial plateau has not performed well in the lateral compartment, leading to a high rate of dislocation. For this reason, the Domed Lateral UKA with a biconcave beari…
View article: Biomechanical and Clinical Effect of Patient-Specific or Customized Knee Implants: A Review
Biomechanical and Clinical Effect of Patient-Specific or Customized Knee Implants: A Review Open
(1) Background: Although knee arthroplasty or knee replacement is already an effective clinical treatment, it continues to undergo clinical and biomechanical improvements. For an increasing number of conditions, prosthesis based on an indi…
View article: Biomechanical effect of a lateral hinge fracture for a medial opening wedge high tibial osteotomy: finite element study
Biomechanical effect of a lateral hinge fracture for a medial opening wedge high tibial osteotomy: finite element study Open
View article: Effects of contact stress on patellarfemoral joint and quadriceps force in fixed and mobile-bearing medial unicompartmental knee arthroplasty
Effects of contact stress on patellarfemoral joint and quadriceps force in fixed and mobile-bearing medial unicompartmental knee arthroplasty Open
Background Unicompartmental knee arthroplasty (UKA) is an effective treatment for end-stage, symptomatic unicompartmental osteoarthritis (OA) of the knee joint. However, patellofemoral (PF) joint degeneration is a contraindication to media…
View article: Reduction in tibiofemoral conformity in lateral unicompartmental knee arthroplasty is more representative of normal knee kinematics
Reduction in tibiofemoral conformity in lateral unicompartmental knee arthroplasty is more representative of normal knee kinematics Open
Aims Commonly performed unicompartmental knee arthroplasty (UKA) is not designed for the lateral compartment. Additionally, the anatomical medial and lateral tibial plateaus have asymmetrical geometries, with a slightly dished medial plate…
View article: RETRACTED ARTICLE: Effect of sagittal femoral component alignment on biomechanics after mobile-bearing total knee arthroplasty
RETRACTED ARTICLE: Effect of sagittal femoral component alignment on biomechanics after mobile-bearing total knee arthroplasty Open
View article: Computational wear prediction of insert conformity and material on mobile-bearing unicompartmental knee arthroplasty
Computational wear prediction of insert conformity and material on mobile-bearing unicompartmental knee arthroplasty Open
Objectives Unicompartmental knee arthroplasty (UKA) is an alternative to total knee arthroplasty with isolated medial or lateral compartment osteoarthritis. However, polyethylene wear can significantly reduce the lifespan of UKA. Different…
View article: Computational biomechanics of knee joint arthroplasty : a review
Computational biomechanics of knee joint arthroplasty : a review Open
Computational models have been widely used for more than four decades to evaluate the mechanical behavior of knee joint arthroplasty. Validated computational models provide a virtual platform to develop optimal articular surfaces which ach…
View article: Biomechanical influence of lateral meniscal allograft transplantation on knee joint mechanics during the gait cycle
Biomechanical influence of lateral meniscal allograft transplantation on knee joint mechanics during the gait cycle Open
View article: Cover Feature: Target Identification of a 1,3,4‐Oxadiazin‐5(6<i>H</i>)‐One Anticancer Agent via Photoaffinity Labelling (Asian J. Org. Chem. 9/2019)
Cover Feature: Target Identification of a 1,3,4‐Oxadiazin‐5(6<i>H</i>)‐One Anticancer Agent via Photoaffinity Labelling (Asian J. Org. Chem. 9/2019) Open
Photoaffinity labelling probes, OPALs, were rationally designed and synthesized to identify interacting protein targets of 1,3,4-oxadiazin-5(6H)-one (LL-2003). The labelling strategy enabled successful photo-crosslinking with target protei…
View article: Biomechanical Evaluation of the Effect of Mesenchymal Stem Cells on Cartilage Regeneration in Knee Joint Osteoarthritis
Biomechanical Evaluation of the Effect of Mesenchymal Stem Cells on Cartilage Regeneration in Knee Joint Osteoarthritis Open
Numerous clinical studies have reported cell-based treatments for cartilage regeneration in knee joint osteoarthritis using mesenchymal stem cells (MSCs). However, the post-surgery rehabilitation and weight-bearing times remain unclear. Ph…