Jindong Wan
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View article: Transcatheter adrenal artery ablation: A preclinical safety assessment in a porcine model
Transcatheter adrenal artery ablation: A preclinical safety assessment in a porcine model Open
TAAE is a feasible and well-tolerated method for targeted adrenal ablation in a porcine model. This study provides foundational preclinical evidence supporting further investigation of TAAE as a minimally invasive, organ-sparing approach f…
View article: Effects of psycho-cardiology care on psychological and clinical outcomes among primary aldosteronism patients undergoing adrenal vein sampling: A randomized controlled study
Effects of psycho-cardiology care on psychological and clinical outcomes among primary aldosteronism patients undergoing adrenal vein sampling: A randomized controlled study Open
Adrenal vein sampling (AVS) is considered the gold standard for the subtyping diagnosis of primary aldosteronism (PA), which is essential for preventing adverse cardiovascular outcomes. Nevertheless, the AVS procedure might induce anxiety …
View article: Role of G-protein-coupled receptor kinase 4 on the dysfunction of renal Mas receptor in hypertension
Role of G-protein-coupled receptor kinase 4 on the dysfunction of renal Mas receptor in hypertension Open
The angiotensin converting enzyme 2/angiotensin-(1–7)/Mas receptor axis plays an important role in the regulation of blood pressure. G protein-coupled receptor kinase 4 (GRK4) has attracted more attentions by modulating G protein-coupled r…
View article: Relationship between first pass effect NLR and PLR in mechanical thrombectomy for acute anterior circulation large-vessel occlusion
Relationship between first pass effect NLR and PLR in mechanical thrombectomy for acute anterior circulation large-vessel occlusion Open
Purpose The study investigated the correlation between the neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) concerning the first-pass effect (FPE) observed during mechanical thrombectomy subsequent to acute ischemi…
View article: Causal association between genetically predicted primary aldosteronism and aortic aneurysm and aortic dissection: A Mendelian randomization study
Causal association between genetically predicted primary aldosteronism and aortic aneurysm and aortic dissection: A Mendelian randomization study Open
Emerging research indicates a potential pathogenic overlap between primary aldosteronism (PA) and aortic aneurysm (AA)/aortic dissection (AD). Despite case reports suggest a potential link between PA and AA/AD, the causality of this relati…
View article: Exploration of the shared gene signatures and comorbidity mechanisms of primary aldosteronism and atrial fibrillation
Exploration of the shared gene signatures and comorbidity mechanisms of primary aldosteronism and atrial fibrillation Open
Background Primary aldosteronism (PA) is a prevalent cause of endocrine hypertension characterized by an excess of aldosterone that can induce proinflammatory, prooxidant and profibrotic effects on the heart. Emerging evidence indicates a …
View article: Association between high-mobility group box 2 and subclinical hypertension-mediated organ damage in young adults
Association between high-mobility group box 2 and subclinical hypertension-mediated organ damage in young adults Open
Background: Hypertension-mediated organ damage (HMOD) is an emerging problem among young adults. The potential role of chronic immune-mediated inflammation in the pathogenesis of HMOD is increasingly being recognized. High-mobility group b…
View article: Adipose-derived exosomes impairs endothelial transient receptor potential vanilloid 4 channels and elevates blood pressure in abdominal obesity
Adipose-derived exosomes impairs endothelial transient receptor potential vanilloid 4 channels and elevates blood pressure in abdominal obesity Open
Aim Large epidemiological studies have found that abdominal obesity is a strong risk factor for hypertension. Impaired endothelium-dependent vasodilation is a hallmark of obesity-induced hypertension. Adipose-derived exosomes can regulate …
View article: Renal denervation in a patient with a highly tortuous renal artery using a guide extension catheter: a case report
Renal denervation in a patient with a highly tortuous renal artery using a guide extension catheter: a case report Open
View article: Feasibility and effectiveness of a single-catheter approach for adrenal vein sampling in patients with primary aldosteronism
Feasibility and effectiveness of a single-catheter approach for adrenal vein sampling in patients with primary aldosteronism Open
View article: Dietary chlorogenic acid ameliorates oxidative stress and improves endothelial function in diabetic mice via Nrf2 activation
Dietary chlorogenic acid ameliorates oxidative stress and improves endothelial function in diabetic mice via Nrf2 activation Open
Objectives Chlorogenic acid (CGA) is an antioxidant dietary factor. We investigated the effects of CGA on endothelial cell dysfunction in diabetic mice and the mechanistic role of nuclear factor erythroid-related factor 2 (Nrf2) in the ant…
View article: Development and validation of a prognostic prediction model for antithrombotic-related chronic subdural hematoma in patients with recent acute myocardial infarction
Development and validation of a prognostic prediction model for antithrombotic-related chronic subdural hematoma in patients with recent acute myocardial infarction Open
This model provided a risk stratification tool to predict unfavorable outcomes in patients with recent AMI with antithrombotic-related CSDH. Because the study was based on ten readily practical and available variables, it may be widely app…
View article: Cinnamaldehyde Ameliorates Vascular Dysfunction in Diabetic Mice by Activating Nrf2
Cinnamaldehyde Ameliorates Vascular Dysfunction in Diabetic Mice by Activating Nrf2 Open
BACKGROUND Oxidative stress is known to be associated with the development of diabetes. Cinnamaldehyde (CA) is a spice compound in cinnamon that enhances the antioxidant defense against reactive oxygen species (ROS) by activating nuclear f…
View article: Trajectories of Waist-to-Hip Ratio and Adverse Outcomes in Heart Failure with Mid-Range Ejection Fraction
Trajectories of Waist-to-Hip Ratio and Adverse Outcomes in Heart Failure with Mid-Range Ejection Fraction Open
Background: Waist-to-hip ratio (WHR) is a strong predictor of mortality in patients with heart failure (HF). However, common WHR trajectories are not well established in HF with mid-range ejection fraction (HFmrEF) persons, a…
View article: Supplementary Material for: Predictors and Management of Antiplatelet-Related Bleeding Complications for Acute Coronary Syndrome in Chinese Elderly Patients
Supplementary Material for: Predictors and Management of Antiplatelet-Related Bleeding Complications for Acute Coronary Syndrome in Chinese Elderly Patients Open
Background/Aims: Bleeding complications after percutaneous coronary intervention (PCI) are strongly associated with adverse patient outcomes. However, there are no specific guidelines for the predictors and management of anti…
View article: Predictors and Management of Antiplatelet-Related Bleeding Complications for Acute Coronary Syndrome in Chinese Elderly Patients
Predictors and Management of Antiplatelet-Related Bleeding Complications for Acute Coronary Syndrome in Chinese Elderly Patients Open
Background/Aims: Bleeding complications after percutaneous coronary intervention (PCI) are strongly associated with adverse patient outcomes. However, there are no specific guidelines for the predictors and management of antiplatelet-relat…