Jinfen Wang
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View article: Deep learning radiomics of elastography for diagnosing compensated advanced chronic liver disease: an international multicenter study
Deep learning radiomics of elastography for diagnosing compensated advanced chronic liver disease: an international multicenter study Open
Accurate, noninvasive diagnosis of compensated advanced chronic liver disease (cACLD) is essential for effective clinical management but remains challenging. This study aimed to develop a deep learning-based radiomics model using internati…
View article: Dynamic changes in liver stiffness measurement by 2D shear-wave elastography predict hepatocellular carcinoma in patients with chronic hepatitis B and well-controlled viremia: a retrospective study
Dynamic changes in liver stiffness measurement by 2D shear-wave elastography predict hepatocellular carcinoma in patients with chronic hepatitis B and well-controlled viremia: a retrospective study Open
Dynamic LSM changes can predict HCC in patients with CHB who have well-controlled viremia, especially in non-cirrhotic patients.
View article: <italic>In vitro</italic> heat insulation efficacy of 5% dextrose versus 0.9% saline during radiofrequency ablation
In vitro heat insulation efficacy of 5% dextrose versus 0.9% saline during radiofrequency ablation Open
Purpose: This study compared the efficacy of heat insulation between 5% dextrose and 0.9% saline in radiofrequency ablation (RFA). Accordingly, temperature variations and maximum temperatures were assessed at identical distances and heat f…
View article: Comparison between spleen and liver stiffness measurements by sound touch elastography for diagnosing cirrhosis at different aminotransferase levels: a prospective multicenter study
Comparison between spleen and liver stiffness measurements by sound touch elastography for diagnosing cirrhosis at different aminotransferase levels: a prospective multicenter study Open
• Spleen stiffness measurement performed by sound touch elastography was proven to have similar applicability and repeatability to liver stiffness measurement in this prospective multicenter study. • Spleen stiffness measurement demonstrat…
View article: A Prognostic Nomogram with High Accuracy Based on 2D-SWE in Patients with Acute-on-chronic Liver Failure
A Prognostic Nomogram with High Accuracy Based on 2D-SWE in Patients with Acute-on-chronic Liver Failure Open
We established and validated a 2D-SWE-based noninvasive nomogram to predict the prognosis of ACLF patients that was more accurate than other prognostic models.
View article: Blastic plasmacytoid dendritic cell neoplasm with skin and bone marrow involvement: Report of three cases
Blastic plasmacytoid dendritic cell neoplasm with skin and bone marrow involvement: Report of three cases Open
An accurate pathological diagnosis is a precondition for treatment, and the diagnosis of BPDCN should be based on a combination of clinical symptoms, pathological characteristics, immunophenotype, and other auxiliary examinations. It is ne…
View article: Deep learning radiomics model accurately predicts hepatocellular carcinoma occurrence in chronic hepatitis B patients: a five-year follow-up.
Deep learning radiomics model accurately predicts hepatocellular carcinoma occurrence in chronic hepatitis B patients: a five-year follow-up. Open
An early and accurate prediction of hepatocellular carcinoma (HCC) is beneficial for individualized treatment and follow-up of chronic hepatitis B (CHB) patients. We aimed to establish a prediction model for HCC by radiomics analysis in CH…
View article: <html>Prognostic impact of c-Rel nuclear expression and <i>REL</i> amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma</html>
Prognostic impact of c-Rel nuclear expression and <i>REL</i> amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma Open
Dysregulated NF-κB signaling is critical for lymphomagenesis. The regulation, function, and clinical relevance of c-Rel/NF-κB activation in diffuse large B-cell lymphoma (DLBCL) have not been well studied. In this study we analyzed the pro…
View article: Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma
Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma Open
(The American Journal of Human Genetics 96, 597–611; April 2, 2015) In the article referenced here, Figure 6B mistakenly includes the immunohistochemical image of AKT1 for normal tissue instead of tumor tissue on the right panel. A correct…
View article: Management of bleeding associated with radiofrequency ablation of benign thyroid nodules
Management of bleeding associated with radiofrequency ablation of benign thyroid nodules Open
Objective This study was performed to explore the effective management of bleeding associated with radiofrequency ablation (RFA) of benign thyroid nodules. Methods Thirty-five patients with benign thyroid nodules who were treated with ultr…
View article: Short-Term Prediction of Available Parking Space Based on Machine Learning Approaches
Short-Term Prediction of Available Parking Space Based on Machine Learning Approaches Open
Reliable short-term prediction of available parking space (APS) is the basic theory of parking guidance information system (PGIS). Based on the Intelligent parking system at the Eastern New Town, Yinzhou District, Ningbo, China, this study…
View article: Clinical-Pathologic Analysis of Breast Cancer With PIK3CA Mutations in Chinese Women
Clinical-Pathologic Analysis of Breast Cancer With PIK3CA Mutations in Chinese Women Open
Purpose: Mutations of PIK3CA have recently been shown to play an important role in the pathogenesis and progression of breast neoplasms. The prevalence of PIK3CA in Chinese breast cancer patients may be underestimated. Therefore, we invest…
View article: CDK6 overexpression resulted from microRNA‑320d downregulation promotes cell proliferation in diffuse large B‑cell lymphoma
CDK6 overexpression resulted from microRNA‑320d downregulation promotes cell proliferation in diffuse large B‑cell lymphoma Open
The molecular and clinical heterogeneity in diffuse large B‑cell lymphoma (DLBCL) has raised a need for the investigation of potential therapeutic biomarkers. MicroRNA‑320 (miR‑320) and CDK6 are both involved in the regulation of cell prol…
View article: A decision tree-based prediction model for fluorescence <i>in situ</i> hybridization <i>HER2</i> gene status in HER2 immunohistochemistry-2+ breast cancers: a 2538-case multicenter study on consecutive surgical specimens
A decision tree-based prediction model for fluorescence <i>in situ</i> hybridization <i>HER2</i> gene status in HER2 immunohistochemistry-2+ breast cancers: a 2538-case multicenter study on consecutive surgical specimens Open
Objective: To investigate the proportion of HER2 gene amplifications and the association between the HER2-IHC-staining pattern and gene status in IHC-2+ breast cancers according to 2013 American Society of Clinical Oncology (ASCO)/College …
View article: Hepatitis C virus positive diffuse large B-cell lymphomas have distinct molecular features and lack BCL2 translocations
Hepatitis C virus positive diffuse large B-cell lymphomas have distinct molecular features and lack BCL2 translocations Open
HCV-positive DLBCL have distinct molecular and pathological features compared to the HCV-negative counterparts.
View article: Complications Following Radiofrequency Ablation of Benign Thyroid Nodules
Complications Following Radiofrequency Ablation of Benign Thyroid Nodules Open
RFA appears to be a safe and well-tolerated treatment modality for BTNs. More research is needed to characterize the complications of RFA for thyroid nodules.
View article: Oncogenic Signaling Pathways and Pathway-Based Therapeutic Biomarkers in Lymphoid Malignancies
Oncogenic Signaling Pathways and Pathway-Based Therapeutic Biomarkers in Lymphoid Malignancies Open
Lymphoma is characterized by heterogeneous biology, pathologic features, and clinical outcome. This has been proven by accumulating pathologic and molecular evidence attributed to underlying aberrant alterations at genetic, epigenetic, tra…
View article: Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma
Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma Open
Background Esophageal squamous cell carcinoma (ESCC) is the sixth most lethal cancer worldwide and the fourth most lethal cancer in China. Genomic characterization of tumors, particularly those of different stages, is likely to reveal addi…
View article: Mutually exclusive mutations in<i>NOTCH1</i>and<i>PIK3CA</i>associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China
Mutually exclusive mutations in<i>NOTCH1</i>and<i>PIK3CA</i>associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China Open
BACKGROUND: Recurrent genetic abnormalities that correlate with clinical features could be used to determine patients' prognosis, select treatments and predict responses to therapy. Esophageal squamous cell carcinoma (ESCC) contains genomi…
View article: Prognostic impact of c-Rel nuclear expression and<i>REL</i>amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma
Prognostic impact of c-Rel nuclear expression and<i>REL</i>amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma Open
Dysregulated NF-κB signaling is critical for lymphomagenesis. The regulation, function, and clinical relevance of c-Rel/NF-κB activation in diffuse large B-cell lymphoma (DLBCL) have not been well studied. In this study we analyzed the pro…