Jingxin Gou
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View article: Formulation and Evaluation of Self-Emulsifying Drug Delivery Systems of Larotaxel for Oral Administration
Formulation and Evaluation of Self-Emulsifying Drug Delivery Systems of Larotaxel for Oral Administration Open
The objective of the present study was to develop a self-emulsifying drug delivery system of larotaxel and evaluate its in vitro and in vivo performance. The prepared larotaxel loaded self-emulsifying drug delivery system spontaneously for…
View article: Neovascularization-directed bionic eye drops for noninvasive renovation of age-related macular degeneration
Neovascularization-directed bionic eye drops for noninvasive renovation of age-related macular degeneration Open
The current treatment of wet age-related macular degeneration (wAMD) relies on monthly intravitreal or intravenously injection of vascular endothelial growth factor (VEGF) inhibitor or photodynamic (PDT) agents to inhibit choroidal neovasc…
View article: Rod-shaped nintedanib nanocrystals improved oral bioavailability through multiple intestinal absorption pathways
Rod-shaped nintedanib nanocrystals improved oral bioavailability through multiple intestinal absorption pathways Open
Nintedanib (BIBF) is a biopharmaceutical classification system II (BCS II) drug that has a good therapeutic effect for the treatment of nonsmall cell lung cancer; however, it shows poor oral bioavailability due to low dissolution and intes…
View article: Synergistic Antitumor Efficacy Mediated by Liposomal Co-Delivery of Polymeric Micelles of Vinorelbine and Cisplatin in Non-Small Cell Lung Cancer
Synergistic Antitumor Efficacy Mediated by Liposomal Co-Delivery of Polymeric Micelles of Vinorelbine and Cisplatin in Non-Small Cell Lung Cancer Open
CoNP-lips are a promising formulation for targeted therapy in NSCLC.
View article: Improving Breviscapine Oral Bioavailability by Preparing Nanosuspensions, Liposomes and Phospholipid Complexes
Improving Breviscapine Oral Bioavailability by Preparing Nanosuspensions, Liposomes and Phospholipid Complexes Open
Breviscapine (BVP), a flavonoid compound, is widely used in the treatment of cardiovascular and cerebrovascular diseases; however, the low oral bioavailability and short half-life properties limit its application. The aim of this study was…
View article: Simple and tunable surface coatings via polydopamine for modulating pharmacokinetics, cell uptake and biodistribution of polymeric nanoparticles
Simple and tunable surface coatings via polydopamine for modulating pharmacokinetics, cell uptake and biodistribution of polymeric nanoparticles Open
A strategy that can modulate biological response such as pharmacokinetics, cell uptake and biodistribution of NPs simply by tunable coatings was established.