Jingchuan Xue
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View article: Reservoir methane emission response to varying organic carbon loads under multiple socioeconomic development scenarios
Reservoir methane emission response to varying organic carbon loads under multiple socioeconomic development scenarios Open
View article: MeP Induces Metabolic Disorder and Liver Damage at Human-Relevant Exposure Levels: Role of the Gut Microbiota
MeP Induces Metabolic Disorder and Liver Damage at Human-Relevant Exposure Levels: Role of the Gut Microbiota Open
Methylparaben (MeP) is a widely used preservative found in many consumer products that leads to extensive human exposure. Despite some health concerns, our understanding of MeP's effects on metabolic homeostasis remains limited. This study…
View article: Urinary exposure level of emerging chemicals in Chinese pregnant women and their associations with oxidative stress
Urinary exposure level of emerging chemicals in Chinese pregnant women and their associations with oxidative stress Open
View article: Exposure to carcinogenic primary aromatic amines and associated health risks among the Chinese general population: A nationwide biomonitoring study
Exposure to carcinogenic primary aromatic amines and associated health risks among the Chinese general population: A nationwide biomonitoring study Open
Primary aromatic amines (PAAs) are a class of chemicals that are produced in large quantities and used widely. However, studies on internal exposure levels of these chemicals in the general population in China are limited. This study prese…
View article: Deciphering the universal role of gut microbiota in pollutant transformation
Deciphering the universal role of gut microbiota in pollutant transformation Open
The gut microbiota represents a critical yet underexplored “second genome” in the host that functions as a key driver of pollutant transformation across Earth’s ecosystems. This review synthesizes the current understanding of over 490 poll…
View article: Prenatal per- and polyfluoroalkyl substances (PFAS) exposure and maternal thyroid homeostasis: Nonlinear, compound-specific, and mixture effects
Prenatal per- and polyfluoroalkyl substances (PFAS) exposure and maternal thyroid homeostasis: Nonlinear, compound-specific, and mixture effects Open
View article: Surface protonation amplifies carbon nitride nanosheet-induced phospholipid extraction: Mechanistic insights into enhanced cytotoxicity
Surface protonation amplifies carbon nitride nanosheet-induced phospholipid extraction: Mechanistic insights into enhanced cytotoxicity Open
The transformation of graphitic carbon nitride (g-C3N4) in biological and environmental systems can significantly alter its properties and toxicity, posing potential risks to human health and biological systems. This study systematically e…
View article: Metabolomics reveals the metabolic disturbance caused by arsenic in the mouse model of inflammatory bowel disease
Metabolomics reveals the metabolic disturbance caused by arsenic in the mouse model of inflammatory bowel disease Open
Arsenic exposure has long been a significant global health concern due to its association with various human diseases. The adverse health effects of arsenic can be influenced by multiple factors, resulting in considerable individual variab…
View article: Enhancing Ppcp and Salt Separation in Polyamide Nanofiltration Membranes with Polydopamine and Zno Functionalized Nanofiber Support
Enhancing Ppcp and Salt Separation in Polyamide Nanofiltration Membranes with Polydopamine and Zno Functionalized Nanofiber Support Open
View article: Changing on the Concentrations of Neonicotinoids in Rice and Drinking Water through Heat Treatment Process
Changing on the Concentrations of Neonicotinoids in Rice and Drinking Water through Heat Treatment Process Open
Neonicotinoids (NEOs) have become the most widely used insecticides in the world since the mid-1990s. According to Chinese dietary habits, rice and water are usually heated before being consumed, but the information about the alteration th…
View article: Deciphering Gut Microbiome Responses upon Microplastic Exposure via Integrating Metagenomics and Activity-Based Metabolomics
Deciphering Gut Microbiome Responses upon Microplastic Exposure via Integrating Metagenomics and Activity-Based Metabolomics Open
Perturbations of the gut microbiome are often intertwined with the onset and development of diverse metabolic diseases. It has been suggested that gut microbiome perturbation could be a potential mechanism through which environmental chemi…
View article: Quantitative multiple fragment monitoring with enhanced in-source fragmentation/annotation mass spectrometry
Quantitative multiple fragment monitoring with enhanced in-source fragmentation/annotation mass spectrometry Open
View article: Changing on the Concentrations of Neonicotinoids in Rice and Drinking Water Through Heating Treatment Process: An Unusual Increase in Imidacloprid
Changing on the Concentrations of Neonicotinoids in Rice and Drinking Water Through Heating Treatment Process: An Unusual Increase in Imidacloprid Open
View article: Occurrence and Fate of Antibiotics and Antibiotic Resistant Genes in a Wastewater Treatment Plant of South China: Removal Performance, Interaction and Host Analysis
Occurrence and Fate of Antibiotics and Antibiotic Resistant Genes in a Wastewater Treatment Plant of South China: Removal Performance, Interaction and Host Analysis Open
View article: Placental transfer of bisphenol diglycidyl ethers (BDGEs) and its association with maternal health in a population in South of China
Placental transfer of bisphenol diglycidyl ethers (BDGEs) and its association with maternal health in a population in South of China Open
View article: Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension
Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension Open
View article: A review of properties, production, human exposure, biomonitoring, toxicity, and regulation of bisphenol A diglycidyl ethers and novolac glycidyl ethers
A review of properties, production, human exposure, biomonitoring, toxicity, and regulation of bisphenol A diglycidyl ethers and novolac glycidyl ethers Open
Although numerous studies have investigated environmental occurrence, human exposure, and toxic effects of bisphenol analogues including bisphenol A (BPA), little is known about closely related chemical classes namely, bisphenol A diglycid…
View article: Proteomics with Enhanced In-Source Fragmentation/Annotation: Applying XCMS-EISA Informatics and Q-MRM High-Sensitivity Quantification
Proteomics with Enhanced In-Source Fragmentation/Annotation: Applying XCMS-EISA Informatics and Q-MRM High-Sensitivity Quantification Open
Enhanced in-source fragmentation/annotation (EISA) has recently been shown to produce fragment ions that match tandem mass spectrometry data across a wide range of small molecules. EISA has been developed to facilitate data-dependent acqui…
View article: Occurrence of Phthalates in Bottled Drinks in the Chinese Market and Its Implications for Dietary Exposure
Occurrence of Phthalates in Bottled Drinks in the Chinese Market and Its Implications for Dietary Exposure Open
Ubiquitous occurrences of phthalic acid esters (PAEs) or phthalates in a variety of consumer products have been demonstrated. Nevertheless, studies on their occurrence in various types of bottled drinks are limited. In this study, fifteen …
View article: Deciphering Microbial Metal Toxicity Responses via Random Bar Code Transposon Site Sequencing and Activity-Based Metabolomics
Deciphering Microbial Metal Toxicity Responses via Random Bar Code Transposon Site Sequencing and Activity-Based Metabolomics Open
Studying microbial interactions with their environment can lead to a deeper understanding of biological molecular mechanisms. In the manuscript, two global techniques, RB-TnSeq and activity metabolomics, were successfully used to probe the…
View article: Single Quadrupole Multiple Reaction Monitoring Q-MRM enables Quantitative Mass Spectrometry
Single Quadrupole Multiple Reaction Monitoring Q-MRM enables Quantitative Mass Spectrometry Open
A single quadrupole combined with enhanced in-source fragmentation/annotation (EISA) was used to perform multiple reaction monitoring (Q-MRM) for quantitative mass spectrometry analysis. EISA amplifies fragmentation of traditional soft ele…
View article: Single Quadrupole Multiple Reaction Monitoring Q-MRM enables Quantitative Mass Spectrometry
Single Quadrupole Multiple Reaction Monitoring Q-MRM enables Quantitative Mass Spectrometry Open
A single quadrupole combined with enhanced in-source fragmentation/annotation (EISA) was used to perform multiple reaction monitoring (Q-MRM) for quantitative mass spectrometry analysis. EISA amplifies fragmentation of traditional soft el…
View article: EISA-MRM: Multiple Reaction Monitoring with Single Quadrupole Mass Spectrometry
EISA-MRM: Multiple Reaction Monitoring with Single Quadrupole Mass Spectrometry Open
Enhanced in-source fragmentation annotation combined with single quadrupole multiple reaction monitoring (EISA-MRM) has been designed for quantitative mass spectrometry analysis. EISA contrasts to traditional electrospray as a soft ionizat…
View article: Lysine metabolism conveys kidney protection in hypertension
Lysine metabolism conveys kidney protection in hypertension Open
Hypertension and kidney disease, two related, common, and severe disease entities, have been repeatedly associated with genomic variants and metabolic alterations of lysine metabolism. Here, we developed a stable isotope labeling strategy …
View article: METLIN MS2 molecular standards database: a broad chemical and biological resource
METLIN MS2 molecular standards database: a broad chemical and biological resource Open
View article: Cloud‐based archived metabolomics data: A resource for in‐source fragmentation/annotation, meta‐analysis and systems biology
Cloud‐based archived metabolomics data: A resource for in‐source fragmentation/annotation, meta‐analysis and systems biology Open
Archived metabolomics data represent a broad resource for the scientific community. However, the absence of tools for the meta‐analysis of heterogeneous data types makes it challenging to perform direct comparisons in a single and cohesive…
View article: Enhanced Electrospray In-source Fragmentation for Higher Sensitivity Data Independent Acquisition and Autonomous METLIN Molecular Identification
Enhanced Electrospray In-source Fragmentation for Higher Sensitivity Data Independent Acquisition and Autonomous METLIN Molecular Identification Open
Electrospray ionization (ESI) in-source fragmentation (ISF) has traditionally been minimized to promote precursor molecular ion formation, and therefore its value in molecular identification underappreciated. Recently a METLIN-guided in-so…
View article: Lipid and Cholesterol Homeostasis after Arsenic Exposure and Antibiotic Treatment in Mice: Potential Role of the Microbiota
Lipid and Cholesterol Homeostasis after Arsenic Exposure and Antibiotic Treatment in Mice: Potential Role of the Microbiota Open
Our results suggest that in mice, the gut microbiota may be a critical factor regulating arsenic-induced LXR/RXR signaling perturbation, suggesting that modulation of the gut microbiota might be an intervention strategy to reduce the toxic…
View article: Serum Metabolomics Identifies Altered Bioenergetics, Signaling Cascades in Parallel with Exposome Markers in Crohn’s Disease
Serum Metabolomics Identifies Altered Bioenergetics, Signaling Cascades in Parallel with Exposome Markers in Crohn’s Disease Open
Inflammatory bowel disease (IBD) has stimulated much interest due to its surging incidences and health impacts in the U.S. and worldwide. However, the exact cause of IBD remains incompletely understood, and biomarker is lacking towards ear…
View article: Exposure to bisphenols and phthalates and association with oxidant stress, insulin resistance, and endothelial dysfunction in children
Exposure to bisphenols and phthalates and association with oxidant stress, insulin resistance, and endothelial dysfunction in children Open