Jun Xu
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View article: Publisher Correction: Single-cell and bulk transcriptomics uncovers PRKD2-driven tumor stemness and progression in multiple myeloma
Publisher Correction: Single-cell and bulk transcriptomics uncovers PRKD2-driven tumor stemness and progression in multiple myeloma Open
View article: Single-cell and bulk transcriptomics uncovers PRKD2-driven tumor stemness and progression in multiple myeloma
Single-cell and bulk transcriptomics uncovers PRKD2-driven tumor stemness and progression in multiple myeloma Open
View article: Influence of the gut microbiota on the pharmacokinetics of tacrolimus in liver transplant recipients: insights from microbiome analysis
Influence of the gut microbiota on the pharmacokinetics of tacrolimus in liver transplant recipients: insights from microbiome analysis Open
Introduction Tacrolimus is crucial for immunosuppression after liver transplantation, but its pharmacokinetics vary markedly among individuals. Emerging evidence suggests that the gut microbiota may influence its metabolism, although the u…
View article: Fecal microbiota transplantation for refractory chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation: a pilot open-label, non-placebo-controlled study
Fecal microbiota transplantation for refractory chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation: a pilot open-label, non-placebo-controlled study Open
View article: Exopolysaccharides from Rhizopus nigricans inhibit proliferation and induce apoptosis in human lung adenocarcinoma A549 cells
Exopolysaccharides from Rhizopus nigricans inhibit proliferation and induce apoptosis in human lung adenocarcinoma A549 cells Open
Objective: To analyse the effects of an exopolysaccharide (EPS2-1) obtained from the fermentation broth of Rhizopus nigricans on the viability and apoptosis of human lung adenocarcinoma (A549) cells. Methods: Lung cancer cells were culture…
View article: Clinical diagnosis and treatment of 37 cases of gallbladder neuroendocrine carcinoma
Clinical diagnosis and treatment of 37 cases of gallbladder neuroendocrine carcinoma Open
View article: The impact of high-altitude and cold environment on brain and heart damage in rats with hemorrhagic shock
The impact of high-altitude and cold environment on brain and heart damage in rats with hemorrhagic shock Open
BACKGROUND: Hemorrhagic shock (HS) causes severe organ damage, worsened by high-altitude conditions with lower oxygen and temperatures. Existing research lacks specific insights on brain and heart damage under these conditions. This study …
View article: Relationship between glucocorticoids and viral load during the Omicron wave in mainland China
Relationship between glucocorticoids and viral load during the Omicron wave in mainland China Open
View article: A novel predictor of unsustained return of spontaneous circulation in cardiac arrest patients through a combination of capnography and pulse oximetry: a multicenter observational study
A novel predictor of unsustained return of spontaneous circulation in cardiac arrest patients through a combination of capnography and pulse oximetry: a multicenter observational study Open
Patients with unsustained ROSC have a poor prognosis. The combination of ΔETCO2 and ΔAUCp showed significant predictive value for unsustained ROSC.
View article: Endothelial extracellular vesicles induce acute lung injury via follistatin-like protein 1
Endothelial extracellular vesicles induce acute lung injury via follistatin-like protein 1 Open
View article: Altered Mitochondrial Functions and Morphologies in Epithelial Cells Are Associated With Pathogenesis of Chronic Rhinosinusitis With Nasal Polyps
Altered Mitochondrial Functions and Morphologies in Epithelial Cells Are Associated With Pathogenesis of Chronic Rhinosinusitis With Nasal Polyps Open
Production of mtROS, disrupted mitochondrial function, and structural changes in nasal epithelial cells might be involved in the pathogenesis of CRSwNP.
View article: Chloroquine Treatment Suppresses Mucosal Inflammation in a Mouse Model of Eosinophilic Chronic Rhinosinusitis
Chloroquine Treatment Suppresses Mucosal Inflammation in a Mouse Model of Eosinophilic Chronic Rhinosinusitis Open
Chloroquine may be used for the treatment of patients with eosinophilic CRS.
View article: The Role of Periostin in the Occurrence and Progression of Eosinophilic Chronic Sinusitis with Nasal Polyps
The Role of Periostin in the Occurrence and Progression of Eosinophilic Chronic Sinusitis with Nasal Polyps Open
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a highly heterogeneous disease with different host defence responses. However, whether periostin and vascular endothelial growth factor (VEGF) are similarly impaired in patients with eos…
View article: Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis
Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis Open
View article: The Serum Profile of Hypercytokinemia Factors Identified in H7N9-Infected Patients can Predict Fatal Outcomes
The Serum Profile of Hypercytokinemia Factors Identified in H7N9-Infected Patients can Predict Fatal Outcomes Open
View article: Epithelium‐Specific Ets‐Like Transcription Factor 1, ESE‐1, Regulates ICAM‐1 Expression in Cultured Lung Epithelial Cell Lines
Epithelium‐Specific Ets‐Like Transcription Factor 1, ESE‐1, Regulates ICAM‐1 Expression in Cultured Lung Epithelial Cell Lines Open
Cystic fibrosis (CF) patients suffer from chronic airway inflammation with excessive neutrophil infiltration. Migration of neutrophils to the lung requires chemokine and cytokine signaling as well as cell adhesion molecules, such as interc…
View article: H5N1 Virus Hemagglutinin Inhibition of cAMP-Dependent CFTR via TLR4-Mediated Janus Tyrosine Kinase 3 Activation Exacerbates Lung Inflammation
H5N1 Virus Hemagglutinin Inhibition of cAMP-Dependent CFTR via TLR4-Mediated Janus Tyrosine Kinase 3 Activation Exacerbates Lung Inflammation Open
The host tolerance mechanisms to avian influenza virus (H5N1) infection that limit tissue injury remain unknown. Emerging evidence indicates that cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP-dependent Cl(-) channel, m…