Jing Tian
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View article: Advanced ovarian cancer with malignant bowel obstruction treated with multidisciplinary therapy resulting in long progression-free survival: a case report
Advanced ovarian cancer with malignant bowel obstruction treated with multidisciplinary therapy resulting in long progression-free survival: a case report Open
Patients with advanced ovarian cancer who are initially diagnosed with an inoperable malignant bowel obstruction may still derive a substantial survival benefit from an integrated multidisciplinary treatment regimen. The findings of this s…
View article: Environmental noise and self-rated health in older surgical patients undergoing general anesthesia: a cross-sectional study of anxiety as a behavioral pathway for healthy aging
Environmental noise and self-rated health in older surgical patients undergoing general anesthesia: a cross-sectional study of anxiety as a behavioral pathway for healthy aging Open
Background Promoting healthy aging—a core public-health objective—demands hospital environments that support functional recovery and well-being. Excessive ward noise, however, is a modifiable environmental factor that may thwart this goal …
View article: Validation of the Longitudinal Effect of an Integrated Nursing Intervention Based on the Integrated Theory of Health Behavior Change (ITHBC) on Multidimensional Health Indicators in Older Radiotherapy Patients
Validation of the Longitudinal Effect of an Integrated Nursing Intervention Based on the Integrated Theory of Health Behavior Change (ITHBC) on Multidimensional Health Indicators in Older Radiotherapy Patients Open
These findings confirm the efficacy of the ITHBC-based nursing model in enhancing cognitive, behavioral, and psychosocial outcomes in older patients undergoing radiotherapy. Structuring geriatric oncology care around behavioral theories, s…
View article: The association between cystatin C and hypertension risk in diabetes patients: A multi-cohort cross-sectional study
The association between cystatin C and hypertension risk in diabetes patients: A multi-cohort cross-sectional study Open
Diabetes mellitus with hypertension (DM + HTN) markedly elevates cardiovascular risks, yet its predictors remain unclear. Analyzing 5210 DM patients from three cohorts, this study identified serum cystatin C (CysC) as an independent risk f…
View article: Alterations of brain white matter network topological properties in overt hypothyroidism
Alterations of brain white matter network topological properties in overt hypothyroidism Open
Purpose This study examined the topological properties of brain white matter networks in overt hypothyroidism (OH) patients and their links to cognitive and emotional dysfunction. Materials and methods Fifty OH patients and 92 healthy cont…
View article: Structural alteration of hippocampal subfields in type 2 diabetes mellitus patients with dyslipidemia
Structural alteration of hippocampal subfields in type 2 diabetes mellitus patients with dyslipidemia Open
T2DM patients with dyslipidemia, especially those with MCI, exhibit significant atrophy in hippocampal subfield volumes, with correlations observed between lipid levels and hippocampal subfield volume changes. These findings suggest that l…
View article: Delayed immune-related adverse events profile associated with immune checkpoint inhibitors: a real-world analysis
Delayed immune-related adverse events profile associated with immune checkpoint inhibitors: a real-world analysis Open
Background Immune-related adverse events (irAEs) typically occur within 3 months of initiating immune-checkpoint inhibitors (ICIs), which has been extensively documented. But the clinical profiles of late-onset irAEs remain inadequately ch…
View article: Structural and functional alterations of the hippocampal subfields in <scp>T2DM</scp> with mild cognitive impairment and insulin resistance: A prospective study
Structural and functional alterations of the hippocampal subfields in <span>T2DM</span> with mild cognitive impairment and insulin resistance: A prospective study Open
Background Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance (IR) and is often accompanied by mild cognitive impairment (MCI). The detrimental effects of T2DM and IR on the hippocampus have been extensively demonstrate…
View article: Efficacy and tolerability of blonanserin in schizophrenia: A systematic review and meta-analysis of randomized controlled trials
Efficacy and tolerability of blonanserin in schizophrenia: A systematic review and meta-analysis of randomized controlled trials Open
Our study suggests that differences in efficacy between blonanserin and other antipsychotics are small and that blonanserin has a different tolerability profile than haloperidol and risperidone.
View article: Association of systemic inflammatory biomarkers with hearing loss: Results from NHANES 1999–2020 analyses
Association of systemic inflammatory biomarkers with hearing loss: Results from NHANES 1999–2020 analyses Open
Background:Hearing loss (HL) is a prevalent global health issue with a complex etiology in whichinflammation plays a significant role. The systemic immune inflammatory index (SII), a novel biomarker reflecting systemic inflammation, is hyp…
View article: Frequency-Specific Alterations of Fractional Amplitude of Low-Frequency Fluctuations in Adult-Onset Hypothyroidism
Frequency-Specific Alterations of Fractional Amplitude of Low-Frequency Fluctuations in Adult-Onset Hypothyroidism Open
Background: The neuropathophysiological mechanisms of brain damage underlying hypothyroidism remain unclear. Fractional amplitude of low-frequency fluctuations (fALFF) has been established as a reliable indicator for investigation of abnor…
View article: Frequency-specific alterations of fractional amplitude of low-frequency fluctuations in adult-onset hypothyroidism
Frequency-specific alterations of fractional amplitude of low-frequency fluctuations in adult-onset hypothyroidism Open
Purpose Abnormal spontaneous neuronal activities associated with cognitive deficits and emotional dysfunction were found in hypothyroidism. However, routine method employs a relatively broader range of spontaneous fluctuations and would mi…
View article: Effects of chin tuck against resistance exercise on post-stroke dysphagia rehabilitation: A systematic review and meta-analysis
Effects of chin tuck against resistance exercise on post-stroke dysphagia rehabilitation: A systematic review and meta-analysis Open
Background Chin tuck against resistance (CTAR) exercise was introduced to substitute for the commonly used Shaker exercise for dysphagia rehabilitation. The effects of CTAR exercise in stroke survivors needs to be validated. Objective To i…
View article: Optimal cut-off value of waist circumference-to-height ratio to predict central obesity in children and adolescents: A systematic review and meta-analysis of diagnostic studies
Optimal cut-off value of waist circumference-to-height ratio to predict central obesity in children and adolescents: A systematic review and meta-analysis of diagnostic studies Open
Introduction Waist circumference-to-height ratio (WHtR) is a simple anthropometric index with good screening power and fast interpretation for early detection of childhood abdominal obesity. This systematic review and meta-analysis aims to…
View article: Supplementary Material for: The reduced gray matter volume and functional connectivity of the cerebellum in T2DM with high insulin resistance
Supplementary Material for: The reduced gray matter volume and functional connectivity of the cerebellum in T2DM with high insulin resistance Open
Introduction: Insulin resistance is widely thought to be a critical feature in type 2 diabetes mellitus (T2DM), and there is significant evidence indicating a higher abundance of insulin receptors in the human cerebellum than cerebrum. How…
View article: Economic Assessment of Food Legumes Breeding in China: Evidence Using a Provincial Level Dataset
Economic Assessment of Food Legumes Breeding in China: Evidence Using a Provincial Level Dataset Open
Advances in crop breeding techniques and economic evaluation are critical to ensuring and improving crop yields and sustainable development. Based on the provincial data on food legumes breeding (FLB) in China from 2001 to 2020, the resear…
View article: Serum Concentrations of Losartan Metabolites Correlate With Improved Physical Function in a Pilot Study of Prefrail Older Adults
Serum Concentrations of Losartan Metabolites Correlate With Improved Physical Function in a Pilot Study of Prefrail Older Adults Open
Losartan is an oral antihypertensive agent that is rapidly metabolized to EXP3174 (angiotensin-subtype-1-receptor blocker) and EXP3179 (peroxisome proliferator-activated receptor gamma [PPARγ] agonist), which was shown in animal studies to…
View article: Trans-cinnamaldehyde protects against phenylephrine-induced cardiomyocyte hypertrophy through the CaMKII/ERK pathway
Trans-cinnamaldehyde protects against phenylephrine-induced cardiomyocyte hypertrophy through the CaMKII/ERK pathway Open
Background Trans-cinnamaldehyde (TCA) is one of the main pharmaceutical ingredients of Cinnamomum cassia Presl , which has been shown to have therapeutic effects on a variety of cardiovascular diseases. This study was carried out to charac…
View article: Clinical Outcomes in Vitrectomized versus Non-vitrectomized Eyes in Patients with Primary Vitreoretinal Lymphoma
Clinical Outcomes in Vitrectomized versus Non-vitrectomized Eyes in Patients with Primary Vitreoretinal Lymphoma Open
Vitrectomy had no effect on the relapse rate in eyes with PVRL. However, the decrease in vitreous cell and debris led to vitrectomized eyes having better visual acuity than non-vitrectomized eyes.
View article: Transcutaneous electrical cranial-auricular acupoints stimulation (TECAS) for treatment of the depressive disorder with insomnia as the complaint (DDI): A case series
Transcutaneous electrical cranial-auricular acupoints stimulation (TECAS) for treatment of the depressive disorder with insomnia as the complaint (DDI): A case series Open
Epidemiologic studies have shown that above 80% of Major depressive disorder (MDD) patients have insomnia disorder (ID) [[1]Steiger A. Pawlowski M. Depression and Sleep.Int J Mol Sci. 2019; 20: 607PubMed Google Scholar], MDD and ID are hig…