Jingjing Xiang
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View article: Transplacental transfer of metformin and interaction of metformin with the uptake transporters of placental trophoblast cells
Transplacental transfer of metformin and interaction of metformin with the uptake transporters of placental trophoblast cells Open
Metformin is among the most widely prescribed antidiabetic agents, with increasingly accepted by women with gestational diabetes mellitus due to its more convenient administration. Knowledge of the interaction of metformin with the uptake …
View article: Combining a novel ensemble model and multiplex methylation SNaPshot assays for saliva age prediction and cross-platform data analysis
Combining a novel ensemble model and multiplex methylation SNaPshot assays for saliva age prediction and cross-platform data analysis Open
View article: Proteomic analysis reveals modulation of key proteins in follicular thyroid cancer progression
Proteomic analysis reveals modulation of key proteins in follicular thyroid cancer progression Open
Background: Cytopathology cannot be used to reliably distinguish follicular thyroid adenoma (FTA) from follicular thyroid carcinoma (FTC), the second most common form of thyroid cancer, because they exhibit nearly identical cellular morpho…
View article: Combining a novel ensemble model and multiplex methylation SNaPshot assays for saliva age prediction and cross-platform data analysis
Combining a novel ensemble model and multiplex methylation SNaPshot assays for saliva age prediction and cross-platform data analysis Open
Background DNA methylation is a pivotal biomarker for age prediction. However, most studies focus on blood-derived data, with limited research on saliva, and the inability to directly analyze methylation data across diverse platforms const…
View article: Research Progress on the Mildew of Bamboo
Research Progress on the Mildew of Bamboo Open
Bamboo is widely cultivated in China, but it is generally prone to discoloration and rapid development. As an important renewable resource, it broads application prospects in various fields such as architecture, furniture, paper making, et…
View article: DFRot: Achieving Outlier-Free and Massive Activation-Free for Rotated LLMs with Refined Rotation
DFRot: Achieving Outlier-Free and Massive Activation-Free for Rotated LLMs with Refined Rotation Open
Rotating the activation and weight matrices to reduce the influence of outliers in large language models (LLMs) has recently attracted significant attention, particularly in the context of model quantization. Prior studies have shown that …
View article: Sex ratio and spatial distribution of <i>Cycas panzhihuaensis</i> in <scp>Sichuan Panzhihua</scp> cycad <scp>National Nature Reserve</scp>
Sex ratio and spatial distribution of <i>Cycas panzhihuaensis</i> in <span>Sichuan Panzhihua</span> cycad <span>National Nature Reserve</span> Open
The sex ratio of the endemic gymnosperm Cycas panzhihuaensis was investigated within a 1 ha permanent plot in the Sichuan Panzhihua Cycad National Nature Reserve, with a total of 1034 individuals. The study was based on the potential sex‐d…
View article: Precise Molecular Engineering of Multi‐Suborganelle Targeted NIR Type‑I AIE Photosensitizer and Design of Cell Membrane‐Anchored Anti‐Tumor Pyroptosis Vaccine
Precise Molecular Engineering of Multi‐Suborganelle Targeted NIR Type‑I AIE Photosensitizer and Design of Cell Membrane‐Anchored Anti‐Tumor Pyroptosis Vaccine Open
Photodynamically induced cell immunogenic death has emerged as an effective antitumor strategy because of its capacity to stimulate anti‐tumor immunity for eliminating primary tumors and metastases. Considering that the short‐lived reactiv…
View article: An Evaluation of the Corrosion Inhibition Performance of Chitosan Modified by Quaternary Ammonium Salt for Carbon Steel in Stone Processing Wastewater
An Evaluation of the Corrosion Inhibition Performance of Chitosan Modified by Quaternary Ammonium Salt for Carbon Steel in Stone Processing Wastewater Open
Chitosan was used as the raw material. A quaternization reaction was carried out between 2,3-epoxypropyltrimethylammonium chloride and water-soluble chitosan to prepare quaternary ammonium salt water-soluble chitosan (QWSC), and its corros…
View article: Analysis and Innovative Strategies of Tax Preferential Policies to Promote the Sustainable Development of Small-Scale Individual Businesses
Analysis and Innovative Strategies of Tax Preferential Policies to Promote the Sustainable Development of Small-Scale Individual Businesses Open
This study conducted an in-depth analysis of the current tax preferential policies for small-scale individual businesses and compared them with similar policies both domestically and internationally, aiming to reveal the advantages and dis…
View article: Combining a Novel Ensemble Model and Multiplex Methylation Snapshot Assays for Saliva Age Prediction and Cross-Platform Data Analysis
Combining a Novel Ensemble Model and Multiplex Methylation Snapshot Assays for Saliva Age Prediction and Cross-Platform Data Analysis Open
View article: Clinical Reasoning: A 60-Year-Old Man With Asymmetric Weakness and Persistent Fever
Clinical Reasoning: A 60-Year-Old Man With Asymmetric Weakness and Persistent Fever Open
Peripheral neuropathies, especially those with atypical features, remain a diagnostic challenge. In this case, a 60-year-old patient presented with acute-onset weakness starting in the right hand then sequentially involving the left leg, l…
View article: Dysregulated Immune and Metabolic Microenvironment Is Associated with the Post-Operative Relapse in Stage I Non-Small Cell Lung Cancer
Dysregulated Immune and Metabolic Microenvironment Is Associated with the Post-Operative Relapse in Stage I Non-Small Cell Lung Cancer Open
The underlying mechanism of post-operative relapse of non-small cell lung cancer (NSCLC) remains poorly understood. We enrolled 57 stage I NSCLC patients with or without relapse and performed whole-exome sequencing (WES) and RNA sequencing…
View article: N6-methyladenosine methylation modification patterns reveal immune profiling in pancreatic adenocarcinoma
N6-methyladenosine methylation modification patterns reveal immune profiling in pancreatic adenocarcinoma Open
View article: Association between plasma somatic copy number variations and response to immunotherapy in patients with programmed death-ligand 1-negative non-small cell lung cancer
Association between plasma somatic copy number variations and response to immunotherapy in patients with programmed death-ligand 1-negative non-small cell lung cancer Open
Objective To determine how patients with non-small cell lung cancer (NSCLC) with programmed death-ligand 1 (PD-L1)-negative and/or a low tumor mutation burden status benefit from immune checkpoint inhibitors (ICI). Methods We determined th…
View article: Classification of Hepatocellular Carcinoma Based on N6-Methylandenosine–Related lncRNAs Profiling
Classification of Hepatocellular Carcinoma Based on N6-Methylandenosine–Related lncRNAs Profiling Open
HCC is one of the most common types of malignancies worldwide and the fourth-leading cause of cancer deaths. Thus, there is an urgent need to search for novel targeted therapies in HCC. 186 m6a-related lncRNAs were screened for subsequent …
View article: Correction for: Curcumin in combination with homoharringtonine suppresses lymphoma cell growth by inhibiting the TGF-β/Smad3 signaling pathway
Correction for: Curcumin in combination with homoharringtonine suppresses lymphoma cell growth by inhibiting the TGF-β/Smad3 signaling pathway Open
View article: Additional file 7 of N6-methyladenosine methylation modification patterns reveal immune profiling in pancreatic adenocarcinoma
Additional file 7 of N6-methyladenosine methylation modification patterns reveal immune profiling in pancreatic adenocarcinoma Open
Additional file 7. Additional Tables.
View article: Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma With Micropapillary Component
Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma With Micropapillary Component Open
Background Micropapillary adenocarcinoma is one of the most aggressive histologic subtypes of lung adenocarcinoma (LADC), and even a minor proportion of micropapillary component (MPC) within the LADC could contribute to poor prognosis. Com…
View article: Adult Primary Pineal Alveolar Rhabdomyosarcoma With FOXO1 Gene Rearrangement and OLIG2 Expression: a Case Report and the Literature Review
Adult Primary Pineal Alveolar Rhabdomyosarcoma With FOXO1 Gene Rearrangement and OLIG2 Expression: a Case Report and the Literature Review Open
Introduction: Alveolar rhabdomyosarcoma (ARMS) is a common malignant soft tissue tumor in child and adolescents. When diagnosed in adults, it is an aggressive, often fatal disease. Intracranial ARMS in adults is rare, especially in the pin…
View article: P35.22 WITHDRAWN
P35.22 WITHDRAWN Open
pulmonary lymphoepithelioma-like carcinoma (PLELC), a rare subtype of non-small cell lung cancer (NSCLC).However, the understanding of the treatment for EBV-infected NSCLC was still elusive.Immunotherapy that targets PD-1/PD-L1 has been ut…
View article: P35.23 Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma with Micropapillary Component
P35.23 Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma with Micropapillary Component Open
Micropapillary adenocarcinoma is one of the most aggressive histologic subtypes of lung adenocarcinoma (LADC), and even a minor proportion of micropapillary component (MPC) within the LADC could contribute to poor prognosis. Comprehensive …
View article: The Diagnostic Role of Computed Tomography for ACR TI-RADS 4–5 Thyroid Nodules With Coarse Calcifications
The Diagnostic Role of Computed Tomography for ACR TI-RADS 4–5 Thyroid Nodules With Coarse Calcifications Open
Objectives: Coarse calcifications are prone to cause echo attenuation during ultrasonography (US) and hence affect the classification of benign and malignant nodules. This study aimed to investigate the diagnostic role of computed t…
View article: <p>Hounsfield Unit Values in ACR TI-RADS 4-5 Thyroid Nodules with Coarse Calcifications: An Important Imaging Feature Helpful for Diagnosis</p>
Hounsfield Unit Values in ACR TI-RADS 4-5 Thyroid Nodules with Coarse Calcifications: An Important Imaging Feature Helpful for Diagnosis Open
PURPOSE: The purpose of this study is to investigate the diagnostic role of Hounsfield unit (HU) values on noncontrast computed tomography (CT) for differentiating benignity from malignancy in the American College of Radiology (ACR) Thyroi…
View article: Renal cell carcinoma associated with idiopathic thrombocytopenic purpura
Renal cell carcinoma associated with idiopathic thrombocytopenic purpura Open
We presented the clinical data of one patient with renal cell carcinoma associated with idiopathic thrombocytopenic purpura in this case report. We reported a 56-year-old man who presented with petechiae and ecchymoses. Laboratory studies …
View article: LINC00511 influences cellular proliferation through cyclin-dependent kinases in papillary thyroid carcinoma
LINC00511 influences cellular proliferation through cyclin-dependent kinases in papillary thyroid carcinoma Open
Background: Proverbially, the incidence rate of papillary thyroid carcinoma (PTC) has increased year by year. Many long noncoding RNAs (lncRNAs) have been discovered having a relationship with tumor genesis tightly recently. Thanks …
View article: Diagnostic value of computed tomography (CT) histogram analysis in thyroid benign solitary coarse calcification nodules
Diagnostic value of computed tomography (CT) histogram analysis in thyroid benign solitary coarse calcification nodules Open
This study was to investigate the diagnostic value of the computed tomography (CT) histogram in thyroid benign solitary coarse calcification nodules (BSCNs). A total of 89 thyroid solitary coarse calcification nodules (coarse calcification…
View article: Evaluation of automated breast volume scanner for breast conservation surgery in ductal carcinoma in situ
Evaluation of automated breast volume scanner for breast conservation surgery in ductal carcinoma in situ Open
The present is a retrospective study examining the use of automated breast volume scanner (ABVS) for guiding breast conservation surgery in ductal carcinoma in situ (DCIS). A total of 142 patients with pathologically confirmed DCIS …
View article: Establishment of a HEK293T cell line able to site-specifically integrate and stably express GDNF by rAAV-2 vector
Establishment of a HEK293T cell line able to site-specifically integrate and stably express GDNF by rAAV-2 vector Open
Background: Using recombinant adeno-associated virus 2 (rAAV-2), we attempted to establish a HEK293T cell line that is able to site-specifically integrate and stably express glial cell line-derived neurotrophic factor (GDNF). Results: Reco…
View article: Diagnostic value of CT artifacts for solitary coarse calcifications in thyroid nodules.
Diagnostic value of CT artifacts for solitary coarse calcifications in thyroid nodules. Open
This study aimed to estimate the diagnostic value of CT artifacts for solitary coarse calcifications (SCC) in thyroid nodules. A total of 78 SCCs (coarse calcifications >2 mm, no definite mass lesion around calcification) in 63 cases recei…